Fluconazole is also sometimes used to treat serious fungal infections that begin in the lungs and can spread through the body and fungal infections of the eye, skin and nails. Fluconazole is also sometimes used to prevent fungal infections in people who are likely to become infected because they have human immunodeficiency virus (HIV) or cancer or have had a transplant operation (surgery to remove an organ and replace it with a donor or artificial organ). Talk to your doctor about the possible risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

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To our knowledge, this is the first demonstration of inactivation of a negative RNA element within a coding region without alteration of the expressed protein. Computer navigation in total knee arthroplasty: where are we and where are we heading? We objectified the classification differences between these categories. Abnormalities of the thalamus are thought to be central to the pathophysiology of schizophrenia.

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Pyruvate oxidation is enhanced by exercise-induced increase in pyruvate dehydrogenase activity and is relatively impaired by low oxygen availability and low mitochondrial oxidative capacity. A new gas-liquid chromatographic procedure for the identification-quantitation of nonulosonates in poly(oligo)meric forms is described. A subclass of LDL, lipoprotein(a), is also of interest with respect to atherogenic potential, particularly since it has a plasminogen-like moiety as part of its structure. Differential expression of IL-10 receptor by epithelial cells and alveolar macrophages. The second step involved the selective removal (or dealloying) of Ag from the alloy nanoboxes with an aqueous etchant based on Fe(NO3)3 or NH4OH.

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Thus, while both alpha 5 beta 1A and alpha v beta 3 are able to support adhesion to fibronectin, alpha v beta 3 dominates in the formation of focal contacts, and alpha 5 beta 1A has a prime function in fibronectin matrix assembly. SETTING AND SOURCES OF DATA: The study was conducted in an academic medical center and was based on analysis of 34,985 patients who completed a 50-item survey rating the care received during a recent outpatient visit to a physician or midlevel provider. Maternal and neonatal effects of remifentanil for general anaesthesia for Caesarean delivery Acinetoferrin and its derivatives, especially those containing a cyclic imide group, were able to deliver iron or gallium into M.

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In the present investigation, pairs of excitatory postsynaptic potentials (EPSPs) were recorded intracellularly from bullfrog paravertebral sympathetic ganglia for an analysis of the site and mechanism responsible for the phenomena of facilitation and depression of ganglionic transmission. Equilibrium swelling measurements of the hydrogels were carried out in distilled water and also in simulated gastric and intestinal fluids. Therefore, in these cases an increased fetal risk could be expected. Extensive direct-tandem organization of a long repeat DNA sequence on the Y chromosome of chinook salmon (Oncorhynchus tshawytscha).

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More importantly, elevated B7-H1 expression is also closely associated with the suppression of T cell immune function. We also observed a correlation between MRI findings and severity of both clinical and histological manifestations, suggesting that MRI may provide prognostic criteria in focal myositis. The diagnostic workup still revolves around fine needle aspiration biopsy. Investigation of oral alpha-streptococcus showing inhibitory activity against pathogens in children with tonsillitis.

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In the second half, deciduoma could not be induced and few histological reactions were recognized. General aspects and progress of the etiological survey in experimental oncology The numerical values of these volume changes have allowed the construction of a thermodynamic cycle that includes many of the redox intermediates. Central, newly obtained experimental and clinical results that have profoundly improved our understanding of the origin and biology of anti-DNA antibodies will be presented and discussed below.

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The chapter also describes the characteristics of each technique, including the advantages and disadvantages of each method. However, a gradual deterioration of mechanical properties, associated with collagen necrosis and an ineffectual reparative response, was evident.

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Human coronary endothelial cells (HCAECs), human umbilical endothelial cells (HUVECs), and human coronary smooth muscle cells (HCMSMCs) were cultured and identified. Posttranscriptional regulation by the human immunodeficiency virus type 1 Rev and human T-cell leukemia virus type I Rex proteins through a heterologous RNA binding site. This study evaluated the role of COX-2-derived PG in radiation treatment by using the NMF11.2 mammary tumor cell line originally obtained from HER-2/neu mice that overexpress HER-2/neu. Significant increases in large densely granular mast cells occurred at 2 MED in the lower dermis, in association with a UVB-exacerbated granulomatous reaction. Data were collected from patient records and nursing observation records.

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The proposed measure is an entomological indicator that estimates the number of risky bites that a human being receives per night. A case of metachronous presentation of renal cell carcinoma and testicular seminoma is reported. Role of cyclic nucleotides in the regulation of mitochondrial calcium uptake and efflux kinetics. Respiratory symptoms and pulmonary function in coal miners: looking into the effects of simple pneumoconiosis. We identify here at least four different proteins that bind specifically to the insulin GAGA box.

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A simple barrier system was used successfully to exclude Mycoplasma pulmonis and Sendai virus from a conventional mouse room. Thyroid hormone correlates of sensation seeking and anxiety in healthy human females. Nine healthy, young male volunteers at rest after an overnight fast.

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Shift of the fetal sex ratio in hCG selected pregnancies at risk for Down syndrome. The splenic epidermoid cyst is a true congenital one, that can cause signs and symptoms, or suffer complications. HA synthesis by the cells was not significantly augmented by TNF alpha or by IFN gamma. This potentially important contribution of oncogenes to tumor growth and development may prove to have an impact on how various signal transduction inhibitors that are now in early phase clinical trials, e.g., monoclonal neutralizing antibodies to the human EGF receptor (70), function in vivo as anti-tumor agents.

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We show that hair follicles in the resting phase express low levels of Jagged1 and Hes1, and other Notch target genes are undetectable. Major adverse events are less frequent with the endograft despite the need for late reinterventions. The yeast cells with high trehalose level (HT cells) had higher viability than those with low trehalose level (LT cells) after freeze drying and storage for 90 days.

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The data were collected by using the self-care agency scale and a questionnaire designed to determine the socio demographic features, and evaluated by means of percentage calculation and chi-square tests. The methodology will be illustrated using the controlled introduction of a new technology, called microarray analysis, into the clinical practice of breast cancer treatment as a case study. The various procedures are described, and the sensitivity of the test is discussed. Recent biomedical studies have produced new theories about how alcohol affects neurotransmitters in the brain. Smoke and mirrors: magnified beliefs that cigarette smoking suppresses weight.

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granulosus and in phylogenetic analysis of the genus Echinococcus. For those patients who had computed tomography scans available, the Sanders et al classification was applied and documented.

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Overexpression studies demonstrate that both proteins have the same dorsalizing properties as their Xenopus homologues. Valve-surgery patients had the lowest incidence and patients with combined procedures had the highest incidence of cerebral complications. While variations in Lp2A-I PI content have little effect on the interfacial binding of LCAT, increasing POPC content appears to directly increase the binding affinity of LCAT for the different Lp2A-I particles. We conclude that resistance of macrophages and resistance of the whole animal are two facets of the same phenomenon.

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Using H2SO4 the EEP was found at a lower pH value than compared with the point of maximum coacervate yield. The essence of the method is to discriminate between good and bad sensor measurements and combine only the good readings to derive an optimal heart rate estimate. The existence of the Medical Subject Headings and MEDLINE make the biomedical domain a prime candidate for application of this technique. Possible PFCL invasion into an open optic-haptic junction in three-piece IOLs could not be excluded using this method. Occurrence and clinical correlates of psychiatric comorbidity in patients with psychotic disorders.

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Although preincubation with DEX was sufficient to induce a type 2 switch in short-term mitogen cultures, PBMC cultures for extended periods of time required DEX at the initiation and throughout the duration of culture. Gossypol inhibits proliferation of endometrioma cells in culture. Cross-sectional mail survey of a probability sample of primary care physicians. Stated versus actual lipase activity in pancreatic enzyme supplements: implications for clinical use. The severe toxicity and erratic absorption relegated this compound to the research laboratory until the 1980s when the topoisomerase enzyme was identified as the cellular target of camptothecin, the topoisomerase enzyme was found to be overexpressed in cancer cells and a structure-activity relationship was determined for camptothecin.

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Our results suggest that TTCE may affect dolichol functions in rat liver. Specifically, individuals with the TI deletion had more compulsions regarding personal cleanliness (i.e. Recent advances in the field of micro-analytical systems can be classified according to instrument performance (which refers here to the desired property of the analytical tool of interest) and two important features specifically related to miniaturisation, namely reduction of the sample volume and the time-to-result.

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Interleukin-10 (IL-10) is a pleiotropic cytokine with potent antiinflammatory effects in many cells lines. The protocol can be used for routine purposes or for more detailed kinetic analyses. As the plant matures, flowers and develops seeds, these sinks receive a relatively high proportion of the available assimilate.

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Presenting to an emergency department was found to be three times more likely for women aged 30 to 59 years with all three risk factors and ten times more likely for women aged 60 years or more who reported high risk alcohol consumption and high psychological distress than women of these age groups without these risk factors. Surgical resection was performed and no evidences of tumour recurrence were observed after 6 years of the treatment. Immunoblastic lymphadenitis is a T-cell immune hyper-response to antigenic stimulation.

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Hypericum extract: a superior option for the treatment of mild-to-medium severe depression Exposure of dexamethasone-treated cells to Alamar Blue did not interfere with the performance of apoptosis assays, such as flow cytometric analysis of PI-stained cells and microscopic examination of ethidium bromide/acridine orange-stained cells. Bisphosphonates are attractive antiresorptive drugs for osteoporosis. The 47 kDa protease showed activity on several macromolecules such as elastin and collagen type VI besides gelatin and casein.

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Some apparatuses are highly sensitive and can only be handled by highly trained persons. Depressive symptoms were assessed in 184 newly diagnosed diabetic subjects and 768 randomly selected individuals without diabetes.

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Improving the detection of antibodies to hepatitis C virus in blood component donors However, adrenalectomy 2 or 8 days before did not modify CRF secretion induced by IL-1 from the in vitro perifused hypothalami. Since the closure of the IMLS fellowship course in 1972, fewer opportunities for specialised training in parasitology are available: more training is needed. Anti-CagA antibodies are associated with atrophic gastritis in a population at high gastric cancer risk: a morphometric study by computerized image analysis. Pediatricians and pediatric dentists should consider the need for water analysis prior to supplementation and should continue the use of fluoride supplements until 16 years of age.

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The hearing loss begins peripherally and may become central as the condition progresses. Of the four patients with major vascular injuries due to complicated orthopaedic injuries, two had successful repair of the vascular injury but the other two underwent amputation. The tissues with high levels (greater than 10 mug/g) of drug at the one hour period were kidney cortex and medulla, urine, blood serum and the injection site. Alterations in homologous recombination (HR) and non-homologous end-joining (NHEJ) also contribute to the development of pancreatic cancer. Dendritic cell-like cells (Mo-DCs) generated from peripheral blood monocytes with interleukin-4 (IL-4) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been used as tools to treat cancer patients (DC-vaccines).

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The STE5 protein contains a putative PEST motif for ubiquitin-dependent protein degradation, and its level may be important for regulation of pheromone signal transduction. Photographs from some printers were as good or better than traditional darkroom prints of the same film when evaluated for resolution, image quality, and costs.

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These conditions often give rise to social, legal, and ethical concerns which impede the proper treatment of these patients, commonly involving the prescription of anti-psychotics for non-psychotic indications. Study of indications for fusafungin, a new antibiotic, in dermatology Our observations define an unusual form of cooperation between bHLH and ETS proteins and suggest mechanisms by which tissue-restricted and ubiquitous factors combine to generate tissue-specific enhancer activity. However, determining treatment efficacy by clinical evaluation suffers from limited objectivity, sensitivity, and specificity for the underlying pathophysiologic aspects, which may constitute the target of a given therapy. After polymerization the embedded filter was sawn into small blocks and the cell layer was sectioned tangentially on an ultramicrotome.

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In localized scleroderma, a marked increase in lysyl oxidase was observed in mononuclear cells and fibroblasts near blood vessels in the lower dermis and in the subcutaneous fat tissue, in addition to the extracellular deposits between collagen bundles. Local expression of IL-4 in ACD indicates either TH2 or TH0 immunoregulation in some allergic contact dermatitis lesions. The techniques employed were CsCl density gradient centrifugation, glycerol gradient centrifugation, and ethidium bromide-CsCl density gradient centrifugation in combination with nucleic acid hybridization, as well as electron microscopy contour length measurements of purified circular EBV DNA. Transdermal fentanyl: little absorption in two patients with systemic sclerosis?

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In cases where surgical treatment is advocated, laparoscopic surgery is a safe and feasible technique with reasonable operating time as well as limited blood loss, hospital stay and convalescence. To achieve the highest insufflation selectivity and reduce patient discomfort, we have devised a small caliber balloon-tipped catheter to easily reach even the minor branches of the bronchial tree.

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A Pygeum africanum extract with so-called phyto-estrogenic action markedly reduces the volume of true and large prostatic hypertrophy. Our study suggests that competition alone is not a sufficient condition for the development of resource polymorphism because overly strong competition is typically associated with increased temporal variation (environmental instability). Its spectral properties are very similar to those of the other cytochromes c3 (molecular weight, 13,000) of Desulfovibrio and show that it contains four hemes per molecule. Anesthesia and surgery exert immunomodulatory effects and some authors argue that they may exert additive or synergistic influences on vaccine efficacy and safety.

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Acute hydrothorax can be prevented and treated using graduated cycle volumes, and is not a contraindication for peritoneal dialysis. Nebulizable medications often are mixed to simplify asthma medication regimens. Effect of estradiol on the rat brain synaptosomal phosphoinositide composition

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Although rapid pathogen-induced AtWRKY33 expression does not require salicylic acid (SA) signaling, it is dependent on PAD4, a key regulator upstream of SA. Relative increase in apolipoprotein CII content of VLDL and chylomicrons in a case with massive type V hyperlipoproteinaemia by nicotinic acid treatment. One hundred eighty-seven eyes of 187 normal subjects (age range, 5-75 years) who satisfied the inclusion and exclusion criteria were included.

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DNA fingerprints were generated by gel electrophoresis of PCR products derived from either unlabeled standard repetitive sequence-based oligonucleotide primers or fluorescent primers. Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. Absorption of the tumor nucleolar antibodies with whole tumor cells or whole liver pressate did not alter band formation with no-Ag1.

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The relationship among ethnic identity, psychological well-being, and intergroup competence: an investigation of two biracial groups. Health promotion through self-care and community participation: elements of a proposed programme in the developing countries. Field-induced hexagonal blue phases in positive and negative dielectric anisotropy systems: Phase diagrams and topological properties.

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Between August 1997 and February 2000 a randomised clinical trial with a total of 200 patients was performed. Invasive bladder cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up.

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The future outlook of surgical therapy for carcinoma of the esophagus. Drug provision within the German statutory health insurance system has undergone several reforms, including the introduction of drug macrobudgets in 1993.

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This paper provides theoretical estimates of the signal-to-noise (S/N) ratio advantage that can be gained from a radio microphone (FM) system used with an environmental (EV) microphone, compared with the S/N ratio delivered by a conventional hearing aid alone. Tensin is a cytoskeletal protein that links integrins to the actin cytoskeleton at sites of cell-matrix adhesion. Forty-one samples were analyzed by primed in situ labeling: 35 direct preparations of chorionic villi and 6 uncultured amniotic fluid samples. This study of patients treated in clinical practice with infliximab demonstrated that secondary non-response occurred in around half the patients in the first year.