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Tenofovir is an antiviral medicine. It is prescribed for human immunodeficiency virus (HIV) infection. It slows the progress of HIV infection, but it is not a cure. HIV destroys cells in the body, called CD4 T cells. These cells are a type of white blood cell and are important because they are involved in protecting your body from infection. If left untreated, the HIV infection weakens your immune system so that your body cannot defend itself against bacteria, viruses and other germs. Tenofovir slows down the progress of HIV infection by reducing the amount of virus in your body. It does this by stopping the virus from copying (replicating) itself.

Other names for this medication:
Tenofovir, Atripla, Tenvir, Trioday, Truvada, Viraday, Viread,

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Tenofovir is used in combination with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immunodeficiency syndrome (AIDS).

Tenofovir will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay problems that are usually related to AIDS or HIV disease from occurring. Tenofovir will not keep you from spreading HIV to other people. People who receive this medicine may continue to have some of the problems usually related to AIDS or HIV disease.

Tenofovir is also used to treat chronic (long-term) hepatitis B virus (HBV) infection.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Powder

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Hybrid method coupling fluctuating hydrodynamics and molecular dynamics for the simulation of macromolecules. After analgesia with 5 mg nalbuphine hydrochloride administered subcutaneously, the response to FAS was again recorded. Quantitation of IFN types I and II in the culture supernatant showed the presence of IFN-beta as the major cytokine, while IFN-gamma was undetectable. Synthesis and elaboration of functionalised carbohydrate-derived spiroketals.

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Munc18 blocks syntaxin interactions with cognate SNARE proteins and thereby act as an inhibitor of exocytosis. All components of the inner ear derive from the embryonic otic placode. Studies in experimental animals, initially the rabbit and more recently the mouse, have been a great importance in establishing present day concepts concerning the phenomenon of herpesvirus latency. In summary, viral infections of the skin that occur at adolescence include those typical of childhood and those associated with sexual maturity.

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The polymorphism in IL-6 gene promoter (-174 G/C) does not appear to be a genetic risk factor for HSP in Northwest Spain. Enzyme-linked immunosorbent assay (ELISA) and agar gel immunodiffusion (AGID) were conducted using the expressed proteins to detect antibodies from experimentally infected horses. The authors describe a case of a classical variant of papillary thyroid carcinoma arising in a struma ovarii of a 22-year-old female. Finally, early changes occurring within photoreceptors can now be studied. To determine the role of MYLK gene variants in asthma among African Caribbean and African American populations.

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used as perioperative analgesics. Differential subcellular localization of Ror tyrosine kinase receptors in cultured astrocytes. Antimicrobial agents are widely utilized in the prevention and treatment of infection in patients with cardiovascular diseases.

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The considerable effort invested in the development of QSARs during the past decade has resulted in only rather modest progress. Irreversible thermal denaturation of Torpedo californica acetylcholinesterase. Thirty-day AO was defined as AMI, percutaneous coronary intervention, coronary artery bypass grafting (CABG), or cardiac death occurring within 30 days of initial ED visit. Low energy electron irradiation induced deep level defects in 6H-SiC: the implication for the microstructure of the deep levels E1/E2.

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These results indicate that this benzophenone-based isoprenoid analogue will be useful for identifying enzymes that utilize farnesyl diphosphate as a substrate. Use of this model enables individualization of vancomycin dosage in patients receiving concurrent aminoglycoside therapy and minimizes vancomycin serum concentration monitoring. Purification of T lymphocytes into CD45RO and CD45RA subsets showed that only naive CD45RA T lymphocytes are co-stimulated by anti-CD31 mAb.

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Five month survival in a calf supported with an intraventricular axial flow blood pump. Involvement of the CNS by a granulosa cell tumor of the ovary is rare. Four different mixtures were used and a fifth was designed on the basis of this experience.

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In the gut lumen, however, regulatory peptides retain their biological activity much longer, especially in newborn and young animals. Then, activation of NF-kappaB in the lungs was assessed by conducting electrophoretic mobility shift assays (EMSA). Radiographic observation showed successful new bone formation in the lengthened area. The water content of the airway increased after the 2nd antigen inhalation.

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According to the kinetic model of Huxley and Simmons, the extent that a cross-bridge progresses through the working stroke depends on the mechanical conditions. For example, all the cells that compose the final sense organ are derived from a unique cell through a well-established lineage, whereas each muscle is formed by fusion of myoblasts that belong to two different populations: a founder cell and a pool of fusion competent cells. Further experiments combining this method with measuring the activity of particular tyrosine kinases of the activation cascade may bring the necessary information explaining the nature of T-cell dysfunction. Forty patients with uterine myoma diagnosed histologically were treated by abdominal simple total hysterectomy using an intraoperative blood salvage apparatus.

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These glomerular changes have not been reported previously as a complication of this form of malignancy and are similar to lesions reported in newborn rats and mice receiving interferon alpha. Penetration of human vaginal and buccal mucosa by 4.4-kd and 12-kd fluorescein-isothiocyanate-labeled dextrans. The equivalence of two assays is determined using the sensitivity and specificity relative to a gold standard. Report of 2 cases observed in adults and treated by hepatic resection The proper approach to the patient at risk of falling is to address the contributing factors that place the patient at risk and, where possible, correct them.

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The femora of normal-growing beagle dogs were examined histologically at 6 and 12 mo of age to clarify the morphologic changes occurring in the femoral growth plate as background data for studies of chondrosseous toxicology. It is plausible that she developed recurrent rather than de novo lupus nephritis following transplantation. In conclusion, morphometrical analyses reveal a large amount of significant differences which may be related to speciation and to the divergence of ecological niches. The number of DCs present in the specimens was quantified microscopically and compared statistically with patient outcome and staging. Parenting children with anorectal malformations: implications and experiences.

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A reduction in bed availability for observation purposes shortens patient length of stay. The other two groups of 5 adult males had adrenal androgen levels suppressed or stimulated while receiving dexamethasone or ACTH. Patient compliance: a review of the research with implications for psychiatric-mental health nursing. Expression, selection, and organellar targeting of the green fluorescent protein in Toxoplasma gondii.

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To assess the utility of spiral computed tomography (CT) with three-dimensional reconstruction in defining aneurysms of the Circle of Willis. The study indicated that calcium and vitamin D-deficiency in adult rats is related with changes of the mandibular bone and teeth.

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Effect of prostaglandin A and tunicamycin on rotavirus assembly VLDL from type III plasma consisted of spherical particles, diameter 31-81 nm, morphologically indistinguishable from normal VLDL.

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The study was single centre, randomised, single blind, 4 treatment crossover design. We postulated that Amadori-modified glycated albumin modulates TGF-beta 1 expression in mesangial cells, and that TGF-beta 1 participates in mediating the glycated albumin-induced increases in mesangial cell matrix production. Quantitative determination of domperidone in rat plasma by high-performance liquid chromatography with fluorescence detection. We show that the ubiquitously expressed v-SNARE cellubrevin localizes to the basolateral membrane and to recycling endosomes, where it colocalizes with AP-1B. Uniform guidelines should be developed to address safety issues associated with sunless tanning booth use.

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Endogenous endophthalmitis caused by Scedosporium apiospermum treated with voriconazole. Patch test results in hairdressers with contact dermatitis in Greece (1985-1994). Major studies related to this topic have been identified through MEDLINE searches and through the published literature.

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The present study evaluates the extent of axillary dissection as part of the primary surgical treatment of operable breast cancer. It is usually not known whether central airway malacia contributes to airflow obstruction. Studies on the single-shelled rotavirus receptor with a synthetic peptide derived from the cytoplasmic domain of NS28.

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The present study is the first linking GI hormones to the leading cause of infant mortality and provides a novel insight for neurogenesis in which materno-fetal communication through GI hormones appears to be important. Even so, correlations of this magnitude can have important deleterious effects on the power to detect important treatment effects in an otherwise well-designed and well-executed study. Primary antiphospholipid syndrome with acute myocardial infarction recanalised by PTCA. Concentrations of these elements, primarily vehicle contributed, compare favorably with those from other studies of RDS. Prior need for hip joint replacement surgery and whether general practice and hospital services were being used as assessed by the questionnaire.

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The central message of this review is that tumor cells are protected from immune damage in hypoxic and immunosuppressive tumor microenvironments due to the inactivation of anti-tumor T cells by the combined action of these two hypoxia-driven mechanisms. We conclude that ketamine/medetomidine, followed by reversal with atipamezole, is an effective technique for chemical restraint in the mouse. For surgeons its reliability and utilization remain questionable. The current in vivo tests can be costly and prolonged and can involve the use of many laboratory animals, making them inappropriate for generalized use on existing chemicals.

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The number of current users of the index prostaglandin at day 180 was the sum of patients who persisted with the index prostaglandin plus patients who restarted the index prostaglandin after a discontinuation. To clarify the significance of anorectal myectomy (ARM) in childhood patients with short segment hypoganglionosis (Hypo), we analyzed the clinical features of these patients before and after ARM. The present investigation supports the assumption that daytime tiredness in nonapneic patients can be linked to increased respiratory effort during sleep and that continuous esophageal pressure measuring may contribute to assessment of this condition. Levels of IL-6 and TNF-alpha in depressed patients were higher than in normal controls. Imaging studies of human and nonhuman primate brain will be presented, and the potential clinical applicability of these agents will be discussed.

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In contrast to white blood cell scanning, which is of limited use in the spine, the low uptake of 99mTc ciprofloxacin into normal bone marrow, combined with its claimed bacterial specificity, makes it, theoretically, an ideal candidate for evaluating postoperative spinal infections. Because it is an important way to achieve an effective weight gain, educational programs for nonspecialized health professionals, as well as regular pediatric follow-up and specialized multi-professional teams, could improve nutritional intake and could move the schedule for surgical procedures forward.

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We also evaluated the effect of the anti-CD4 mAb on syngeneic and allogeneic graft survival in diabetic NOD recipients. The polypeptide contained the same amino acid sequence as N-terminal amino acid sequence of the enzyme and exhibited no homology with any previously published protein sequences. The absolute grey values of the pixels changed when the brightness of the images or other conditions changed. Thus we sought to identify whether changes in breathing patterns occur with the use of a specific face mask, because these patterns are accepted as representative of normal speech breathing.

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Imaging of calcium release in inositol 1,4,5-trisphosphate-sensitive internal stores in permeabilized HSY cells using fluorescent indicators. It is proactive, patient-centered, data-generating, and establishes clear accountability. Moreover, since the immunocytochemical images were similar in wildtype and ERalpha KO mice, these studies suggest that the lack of ERalpha does not influence the expression of ERbeta in the central nervous system. Hostility and serum homocysteine as cardiovascular risk factors in Korean patients with coronary artery disease.

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However, whether blood trace element changes exist that are related to changes in the cardiovascular system are, in most cases, unknown. There has been, and there continues to be a lot of effort in identifying new prognostic factors that have a biologic rationale and these will be discussed. Fluorosis, osteomalacia and pseudohyperparathyroidism in a patient with renal failure. A 7-year-old boy with multiple severe disabilities presented with an acutely reduced level of consciousness, vomiting and progressive dyspnoea.

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We demonstrate that the interactions are dependent upon the presence of a tyrosine kinase, an SH2 domain and a tyrosine containing substrate. Effects of filipin on the structure and biological activity of enveloped viruses. Qualitative intruder-state problems in effective Hamiltonian theory and their solution through intermediate Hamiltonians. A thick, sacrificial carbon coating was identified as a method of reducing defects from the FIB process which included film shrinkage and pore deformation.

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Sexually transmitted diseases (STDs) are a serious health problem for adolescents, occurring in an estimated one-quarter of sexually active teen-agers. Today therapeutic strategies are seen in the first stage of dealing with depressed homicide-suicide attempters.

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To make changes in refraction comparable, vertex distances for the refractions and keratometric index of refraction were considered. Comparative bioavailability of josamycin, a macrolide antibiotic, from a tablet and solution and the influence of dissolution on in vivo release.

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1) To describe the prevalence of eight injury-prone behaviors (IPBs) and the associations of these behaviors with ten standard chronic disease and sociodemographic risk factors (CDSRFs) among internal medicine patients and 2) to identify a subset of patients with multiple IPBs who might be at particularly high risk of injury. Biochemical and immunohistochemical estrogen and progesterone receptors in adenomatous hyperplasia and endometrial carcinoma: correlations with stage and other clinicopathologic features. In the present paper, we review and discuss new modalities of therapy for non-small cell lung cancer (NSCLC) based on biological findings. Both of these approaches at times are technically difficult and time-consuming. Gene-gene and gene-environment interactions between alcohol drinking habit and polymorphisms in alcohol-metabolizing enzyme genes and the risk of head and neck cancer in Japan.

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Myelin debris was found in cells similar to multipotential glia cells (Vaughn and Peters, 1968) as well as in astrocytes and in few oligodendrocytes. Developmental hemostasis: relevance to thromboembolic complications in pediatric patients. Development of a prediction model involves two components: model building and performance assessment. A lack of efforts aimed at vocational rehabilitation as well as the main emphasis in inpatient services is criticized. This maintains normal gene dosage and regulatory responses, as well as eliminates ambiguities caused by expression of the normal and mutant genes in the same cell.

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Changing patterns of invasive Haemophilus influenzae disease in England and Wales after introduction of the Hib vaccination programme. Inhibition of superoxide anion production in non-stimulated guinea pig peritoneal exudate cells by anti-inflammatory drugs. To minimize systematic influences of sleep duration and non-REM-REM sleep alterations, EEG power was measured over the longest common amount of non-REM sleep stages 2-4 (168.5 min), accumulated from sleep onset onwards. Localized familial redundant scalp: atypical cutis verticis gyrata?

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State-to-state measurements of the vibrational predissociation dynamics of HeCl2. The effect of benzodiazepines and flumazenil on motor cortical excitability in the human brain. Continuous monitoring of brain tissue pressure can now be achieved with intracerebral placement of fiberoptic microtransducers. Psychological status and coping with illness in patients with malignant melanoma. Of five patients treated who had refractory chronic cluster headache and one with refractory episodic cluster headache, four had relief judged excellent.

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The enhanced infection was characterized by an increase in viral DNA and increased HIV p24 protein production. To reduce surgical trauma, we performed minimally invasive Port-Access (Heartport Inc, Redwood City, CA) coronary artery bypass grafting with cardiopulmonary bypass and cardioplegic arrest. For a liquid film resting on an elastomeric layer, substrate deformability has a destabilizing effect, as evidenced by an increase in the maximum growth rate and range of unstable wavenumbers.

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The most important European and American epidemiological data are presented, and the diagnostic strategies and appropriate interventions discussed. To study another potentially frequent thrombogenic polymorphism, C46T in the factor XII gene (F12) (F12C46T).

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Fractionated radiation therapy is frequently used to treat prostate cancer with an underlying assumption that each daily dose of ionizing radiation (IR) results in equal cell killing. While only docetaxel (Taxotere)-based chemotherapy has been proven to improve survival in this setting, a wide range of therapies may be effective for any individual. Treatment of ischemic heart disease with a hypolipoproteinemic drug pericit The lesion of the mitral leaflet was diagnosed with echocardiography and successfully repaired with autologous pericardial tissue. It was found that ultrastructural changes of Candida albicans cells in the presence of Cyclosporin A.

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To determine the frequency of headaches during endovascular procedures (HdEVP) and to define their characteristics and risk factors for their occurrence. According to the 1998 guidelines of the Federal Office for Public Health, the physician will be informed of the screening assay result without the need to await a confirmatory test in case of a reactive screening assay in the first sample.

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Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. Likewise, PLs are more common among women, obese individuals, and those with a shorter duration of HIV infection. Changes in the C/N ratio with time give no indication of progressive N saturation and suggest sudden breakthrough of N in drainage water is not imminent. Facility-level QMs were estimated from minimum data set (MDS) assessments for approximately 31,000 Minnesota nursing home residents in 393 facilities. High curative resection rate with weekly cisplatin, 5-fluorouracil, epidoxorubicin, 6S-leucovorin, glutathione, and filgastrim in patients with locally advanced, unresectable gastric cancer: a report from the Italian Group for the Study of Digestive Tract Cancer (GISCAD).

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Moreover, defective IGF2 and IGF1R protein production was detected in GK pancreatic rudiment as early as E13.5. Co-administration of ezetimibe and simvastatin in acute myocardial infarction. This is also the first study showing that a bacterial beta-CA can be a drug target. Primary abscess of the baclopar tablets for kids psoas muscle caused by Streptococcus milleri.

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After major trauma of the knee joint, conservation and reconstruction of the different bony, ligamentary and soft tissue structures is usually attempted. A correlation between quality of life and objective functional abilities can not always be found. A case of myocardial abscess evaluated by radionuclide techniques: case report. Occurrence of a diverse protozoa population such as the ciliates, Prorodon, Vorticella, Cyclidium, Spathidium, Loxodes, Metopus were observed in stable anaerobic systems and the flagellates, Rhynchomonas, Naeglaria, Amoeboflagellates, Tetramitus, Trepomonas and Bodo during increased VFA concentration and affected periods of biomethanation. Cardiovascular effects of nepicastat cliofar crema antibiotics side (RS-25560-197), a novel dopamine beta-hydroxylase inhibitor.

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High percentages of monocytes were associated with a decreased vazkor 10 mg nedir az HIV-1 replication and proliferation that could not be reversed by addition of antibodies against the cytokines IL-1, transforming growth factor-beta (TGF-beta) or indomethacin. Vitamin C (ASC) is well known as an outstanding antioxidant in animal tissues. In normal rats, dexamethasone (5, ip) increased the content of liver glycogen and decreased the Bmax of glucocorticoid receptors (GCR) in liver cytosol.

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New biologically active triterpenoid saponins from Scabiosa tschiliensis. There was a positive correlation observed between fecal pellet output and GC of colonic transit in response to restraint stress, but not CRF, when the number of excreted feces was suhagra tablet cipla more than three.

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Human lactase-phlorizin hydrolase (LPH) is a digestive enzyme that is expressed in the small intestinal brush-border membrane. Cervical-spine radiology may not be necessary in patients without spinous tenderness in the neck, intoxication, altered level of alertness, or other severely painful injury. Self-efficacy as a predictor of weight change in African-American women. Qigong practice among chronically ill patients during the SARS outbreak. fox 125 mg of clavam 1000 for fish Procoagulant surface exposure and apoptosis in rabbit platelets: association with shortened survival and steady-state senescence.

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In vitro cytokine-primed leukaemia cells induce in vivo T cell responsiveness in chronic myeloid leukaemia. Since the description climadan acne cream of female siblings with unique clinical and biochemical features by Jaeken (1980) and the discovery of unique isoforms of serum transferrin in the patients by Jaeken (1984), more than 120 patients have been diagnosed. Immediate surgical exploration through a median sternotomy is necessary to control the proximal and distal innominate artery.

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During the first stage, a retrograde revascularization of the superior mesenteric and renal arteries from the infrarenal aorta was done, associated in two cases to a metolazone max dose of gabapentin concomitant repair of an infrarenal aortic aneurysm. Its occurrence late after drug-eluting stent (DES) deployment has led to concerns regarding their long-term safety. Structure and expression of several bean (Phaseolus vulgaris) nuclear transfer RNA genes: relevance to the process of tRNA import into plant mitochondria. To address the possibility that they may influence monocyte-endothelial interactions, we used an in vitro assay to examine their effects on the adhesion of monocytes to human umbilical vein endothelial cells (HUVEC).

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A main feature of leaf klavunat bid 1000 mg shqiptarja senescence is the hydrolysis of macromolecules by hydrolases of various types, and redistribution of released materials. Factors influencing the outcome of hyperopic lamellar keratoplasty. Rash from antiepileptic drugs: influence by gender, age, and learning disability.

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The special hemodynamic circumstances of the normal heart having to saltillo minus rapidus tablet pump an excessive amount of blood for a long period of time will influence the chance of survival of this fetus. Participation of young severely disabled children is influenced by their intrinsic impairments and environment. Angiotensin-converting enzyme inhibitor-enhanced renal scintigraphy was performed and the result was interpreted as positive for bilateral renovascular disease.