Warfarin is a type of medicine known as an anticoagulant, or blood thinner.

It makes your blood flow through your veins more easily. This means your blood will be less likely to make a dangerous blood clot.

Warfarin is used to treat people who have had a previous blood clot, such as:

• a blood clot in the leg (deep vein thrombosis, or DVT)
• a blood clot in the lungs (pulmonary embolism)

It's also used to prevent blood clots if you're at high risk of having them in the future.

This includes people with: * have an abnormal heartbeat (atrial fibrillation) * a replacement or mechanical heart valve * a blood clotting disorder, such as thrombophilia * a higher chance of having a blood clot after an operation

Warfarin is only available on prescription. It comes as tablets and as a liquid that you swallow.

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Together, these results suggest that the differential expression of PTPmu within the retina is instructive for RGC guidance and that the magnitude of PKCdelta activation in response to PTPmu signaling results in the distinct cellular behaviors of nasal and temporal RGCs. However, a number of experimental data, together with clinical observations, indicate a stimulatory action of LF in myelopoiesis. The carboxyhemoglobin method for estimating bilirubin production in neonates. Functional complementation of an xcpY mutant required the XcpY protein to be expressed at a low level.

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A postoperative questionnaire and grading scale were used to judge clinical success. Practical peritoneal dialysis--the Tenckhoff catheter in acute renal failure. Sialoadenitis developed in untreated TLR-3-/- mice and in TLR-3-/- mice treated with mouse Y3 RNA, but sialoadenitis was not present in TLR--/-) mice treated with mouse Y1 RNA.

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She needed a thoracentesis for evacuation of the large pleural effusion. We confirm that Ly-49A recognizes the alpha1 and amino-terminal alpha2 domains of Dd by analysis of recombinant H-2Kd-H-2Dd molecules.

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Adrenal cortico-steriods are the major regulators of the RES function and of the synthesis of acute phase proteins. S6 and A1 tags were selected for useful levels of orthogonality in reactivities with the PPTases: the catalytic efficiency, kcat/Km of Sfp-catalyzed S6 serine phosphopantetheinylation was 442-fold greater than that for AcpS. We first examine in detail the particular properties of neuroanatomical connection data. The remaining AEDs dosages could be adjusted as needed, but a new AED could not be introduced.

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Treatment of advanced heart failure in a young man with familial cardiomyopathy. However, this conclusion is limited by the fact that in the present study teachers and nurses had lower than expected breast cancer risk with or without adjustment for established risk factors. To compare types and anatomic distribution of injuries between cross-country skiers using the classic and skating ski techniques. Research in aerobic and anaerobic decomposition of carbohydrates in the saliva

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Isolation of myelin basic protein-specific T cells predominantly from the memory T-cell compartment in multiple sclerosis. Single spike and irregular spike were discharges, however, occurred more frequently during slow-wave sleep. Constipation and diarrhea often represent a major concern and source of discomfort for the cancer patients. This project team recommends viewing family relationships as an integral component where placement is one option on a continuum that includes letters, phone calls, and visits. In our experience, Helicobacter pylori eradication does not favour gastric ulcer healing but does positively influence the subsequent natural history.

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Other abnormalities can be observed in the Bardet-Biedl syndrome, but few cutaneous abnormalities have been described. A more pronounced reduction of migration ability was shown in mouse and rat transformed cells and less in human ones. Markedly attenuated acute and chronic pain responses in mice lacking adenylyl cyclase-5. Characterization of enterococci populations in livestock manure using BIOLOG. In all, 239 different occupations, distributed across 11 occupational categories, were studied.

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No significant differences in either the virion envelope glycoproteins or other major virion proteins were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Calculations of the 1993 YPLL rates for Florida counties with populations greater than 50,000 and of inter-county variability in YPLL rates were used to train county health agencies in the use of YPLL.

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Long-term effectiveness of presacral neurectomy for the treatment of severe dysmenorrhea due to endometriosis. Contribution of epidemiology in Poland for better understanding of the natural history of diseases in gastrointestinal tract. Direct activation of axons outside the STN suggests that other brain regions may be involved in the beneficial effects of DBS when treating Parkinsonian symptoms. Genetic characterization of a human isolate of Puumala hantavirus from France.

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Previous disease, effects of cyclosporin, tacrolimus and steroid immunosuppression and cardiac denervation are major contributory factors. Commonly used discrete dynamic Bayesian networks perform inferior and this result can be attributed to the inevitable information loss by discretization of expression data. These effects of statins may explain their antiatherogenic actions. The amount of knowledge and understanding about the human immune system has expanded rapidly in the past several decades. Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response.

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In addition, there was no difference in individual aqueous humor protein concentration between the two eyes. The role and the future of dentists in the health team of the future. Population-genetic models suggest that this pattern could be caused by an interaction between recombination rate and the efficacy of natural selection.

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lamin A/C, programmed cell death 6 interacting protein) or indirectly (i.e. Conspecific and heterospecific song discrimination in male zebra finches with lesions in the anterior forebrain pathway. At inflammatory sites, proteoglycans are both secreted by activated mononuclear leukocytes and released as a consequence of extracellular matrix degradation.

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Atrazine degradation and residues distribution in two acid soils from temperate humid zone. The movement of the coronary artery after stabilization appears to be still significant. Immunohistochemical staining for EGF receptors was assessed in tumors of human conjunctiva, eyelid, lacrimal glands, and orbit with monoclonal antibodies (EGF-R1 and clone 29.1).

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The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. Drug advertizing with bibliographic citations in a recent court decision Nevertheless, hearing loss remains problematic, and continued efforts are required to improve worker safety.

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This study indicated that there were no significant differences of central corneal thickness between NTG patients and healthy subjects in our clinic. Exposure of HUVECs to LPS for 12 hours caused significant decrease of TFPI protein activities and mRNA expression. We studied receptor matrix proteins on freshly isolated chondrocytes obtained from 10 patients with osteoarthritis (OA). Patient psychoeducation: the therapeutic use of knowledge for the mentally ill.

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After an implantation period of twelve weeks, the bone-implant interface was evaluated histologically. A novel 95-kD protein is located in a linker between cytoplasmic microtubules and basal bodies in a green flagellate and forms striated filaments in vitro.

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Interestingly, G2-arrested cells reinitiated DNA synthesis, resulting in giant cells with high DNA contents. Acoustic pharyngometry may provide access to noninvasive quantitative measurement of velopharyngeal movement and a better understanding of the pattern of movement in C(L)P-patients. Osteochondral defects filled with HA-MA were infiltrated with cells, appeared to integrate well with native tissue, and also accumulated substantial cartilaginous matrix by 2 weeks after surgery. In the organ bath, strips from human and rabbit corpus cavernosum were precontracted and increasing doses of PDE inhibitors were added.

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In combination with surgical extirpation, such hormonally based treatment may be curative of advanced GI cancer. Administration of CMV-specific CD8 lymphocytes was beneficial for immunocompromised hemopoietic stem cell (HSC) graft recipients.

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To characterize aviation fatalities in agriculture, CDC analyzed data on fatal injuries to pilots working in U.S. Muscle or musculocutaneous flaps have been used more for these defects.

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Twenty-three beta-lactamase-producing bacteria were isolated from 16 (43 per cent) patients. Urinary lithiasis induced by sulfamethoxazole in a patient with tetraplegia. In addition, the material examined in this article includes articles published in the journals covered by the Science Citation Index and MedLine. Cumulative live birth rates following IVF in 41- to 43-year-old women presenting with favourable ovarian reserve characteristics. In addition, the compounds also enhance the inhibitory effect of GABA ergic long projection neurones in the substantia nigra and the lateral vestibular nucleus of Deiters.

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Risk factor-based protocols hold some promise to reduce GBS disease, but clinical strategies to promote protocol adherence are needed. An extremely rare case of intramedullary spinal cord metastasis (Carcinoma solidum metastaticum) is presented. Lung inhomogeneities can lead to significant variations in delivered dose between patients treated in a clinical trial. A total of 212 respondents from three age groups valued the same six hypothetical health states using three different methods: a Visual Analogue Scale (VAS) and two variants of the Time trade-off (TTO). Such representations allow us to carry out numerical simulations that provide mechanistic insights into complex behaviours of biological systems and also generate hypotheses that can be experimentally tested.

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EACC-cell cultures were incubated with different concentrations of sulindac sulfone (400 and 800 micromol). These results suggest that NO or a related compound may be either a neurotransmitter or neuromodulator contributing to the autonomic nerve-induced vasodilatation in the submandibular gland of the cat.

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No correlation was found with serum HA concentration and we conclude that serum HA level is of no prognostic significance in breast cancer. The validity of this finding as well as that of the commonly used 2,4-dinitrophenylhydrazine procedure for the measurement of protein carbonyls was recently called into question by Cao and Cutler ((1995) Arch. The role of bile salts in increasing the size of adenomas and their malignant change is accepted.

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Droloxifene (3-hydroxytamoxifen) has membrane antioxidant ability: potential relevance to its mechanism of therapeutic action in breast cancer. Isolation and partial characterisation of highly toxic lectins from Abrus pulchellus seeds. Undulating membraneous structures associated with the endoplasmic reticulum in tumour cells.

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Visual loss depended on the extent of the burn and did not tend to improve despite vasoprotector and corticosteroid treatments. This is exemplified by remaining tendencies within federal and state agencies to use worst-case approaches for exposure assessment. Although largely unidentified, the existence of these genes offers the possibility for their incorporation into dairy breeds through crossbreeding or on an individual-gene basis. Near-complete transection of the median nerve associated with greenstick fractures of the shaft of the left radius and ulna in a 13-year-old boy is described.

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The National Blood Service (England) approach to evaluation of kits for detecting infectious agents. This vector was designed to incorporate a cleavage site for the enzyme Genenase I, a myc peptide tag, and an amber codon between the heavy chain cloning site and the truncated M13 phage gene III. Flow-cytometric enumeration of micronucleated polychromatic erythrocytes in mouse peripheral blood. Ginkgo biloba is not a smart drug: an updated systematic review of randomised clinical trials testing the nootropic effects of G.

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Nonlethal experimental inoculation of Columbia black-tailed deer (Odocoileus hemionus columbianus) with virus of epizootic hemorrhagic deer disease. Effects of uridine on the performance and the metabolism of oxygenated and hypoxic rabbit hearts. Arthritic lesions are currently treated by total knee arthroplasty (TKA). These findings reverse a previous one (Jones, 1989) that was reproduced in Experiment 3 and shown to stem from a small group of unusually difficult target definitions.

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Computed tomography scan showed a right cystic adnexal mass measuring 10 x 10 cm, and another tumor measuring 3 x 2 cm at the right kidney. The cell viability experiment proves the low cytotoxicity of ALG/CHI nanotubes. Nucleoli appeared compact with no evidence for segregation of nucleolar components. The results showed that decidual culture supernatant markedly blocked in vivo antigen presentation by DCs and inhibited their capacity to induce interferon gamma (but not interleukin-10) production by primed lymphocytes.

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An adenovirus survey of poultry flocks during the growing and laying periods. Epidemiology of cleft palate alone and cleft palate with accompanying defects.

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Consequently, both increases and decreases in blood volume are a natural biological stress associated with aquatic and terrestrial environments. Improved EUS performance is sought by providing contextual information to support US probe positioning and identification of features in US images. Here we describe the protocols for negative or reverse detection of proteins, nucleic acids and lipopolysaccharides separated in polyacrylamide electrophoresis gels. The increased contraction of asthmatic ASM cells may be responsible for exaggerated bronchial constriction in asthma.