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A 34-yr-old nulliparous black woman presented with hair loss, facial hirsutism, irregular menses and infertility associated with greatly increased serum total testosterone levels. Microglia activation accompanies PrP(Res) deposition representing an early event in the progression of these diseases. The effect of administered monopreparations on changes in the level of both homologous and heterologous antibodies was tested. Heterotrophic growth at steady state and during transient states caused by the sudden change of the concentration of the limiting factor in the feed medium was investigated experimentally for continuous cultures of Aquaspirillum autotrophicum limited by pyruvate.

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Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth. Detailed prospective and retrospective data collection was therefore undertaken to evaluate the results of surgical intervention in 120 patients who underwent endoscopic sinus surgery. The negative influence of N-mediated TMV resistance on yield in tobacco: linkage drag versus pleiotropy. An electron microscopic contribution to the pathology of the cytocentre.

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Using this information, a pediatric finite element head model will be created, using parametric mesh generation software, to measure head injury in children in a motor vehicle crash. Knowledge of how these systems interact is important for understanding the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA) and to open new therapeutic perspectives. Automatic search for model to simulate the differentiation of T lymphocytes within the thymus. Chlorpropamide inhibited prostaglandin E biosynthesis during vasopressin-, theophylline- and cyclic AMP-stimulated water flow. Between 1979 and 1996, 176 patients with LABC were prospectively managed by chemotherapy (CT)-irradiation (RT)-CT without routine mastectomy.

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In addition, this preference was reversed in subjects trained thirsty (Experiments 1 and 2) if the associated nutrient had been devalued prior to the test or the preference for the nonextinguished cue was attenuated by nutrient devaluation in subjects trained hungry (Experiments 3 and 4). Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells. Placebo-controlled studies are now warranted to evaluate if IvIg treatment also has any effects on the clinical manifestations of PPS. Changes in ERK phosphorylation in IRS-4-depleted cells were independent of ras/raf/MEK1/2- and PI3K/Akt-cascades.

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Hyperlipidemia in a poorly controlled diabetic presenting with lipemic aqueous and lipemia retinalis. Problems of corticosteroid-induced adrenal insufficiency in surgery External validation of the San Francisco Syncope Rule in the Australian context.

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CT irradiation at typical clinical doses results in oversensing of ICRMDs in the majority of devices tested, although the identified effects were predominantly transient. These molecular toxicities can affect non-adipose tissues, and together with secondary effects on lipid and glucose metabolism of changes in body fat mass, help to contribute to the dyslipidemia and insulin resistance characteristic of this syndrome. Two E-rosette (spontaneous rosette with sheep red blood cells)-forming lymphoid cell lines were established.

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This paper describes the development of an ETAAS method for the quantification of the molar gold concentration in HT-29 colon carcinoma cells. This phenomenon merits attention within Sweden, and beyond, in countries with less comprehensive welfare systems. It is argued here that such relatively brief studies of symptom or specific behavioral change do not address what is meant by personality disorder.

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Laparoscopic surgery adapts poorly to apprenticeship models for general surgical training. Reduction in thrombotic events with heparin-coated Palmaz-Schatz stents in normal porcine coronary arteries. Bioabsorbable interference screw for ligament reconstructions in the knee SNMS profiles of nitrogen reveal a distinct tail which is attributed to enhanced diffusion of nitrogen along grain boundaries. If microsatellites are conserved among species, then those developed for one species can be used on related species, which would save the time and effort of developing new loci.

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Proficient deoxyribonucleic acid repair of methylation damage in hamster ERCC-gene mutants. We report herein the unusual case of a 55-year-old man with multiple endocrine neoplasia type 1 presenting as hyperparathyroidism, hyperpituitarism, insulinoma, and gastrinoma with postbulbar duodenal ulcers. A 6.7 kb mRNA of very high abundance was uniquely present on Northern blots containing mRNA or total RNA from the pigment epithelium. One cone type was labelled by the monoclonal antibody COS-1 specific to the middle-to-long wave sensitive visual pigment of the mammals, while the other type was stained by the shortwave-specific monoclonal antibody (OS-2).

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We have previously shown that during vegetative growth, AppA protein is partly accumulated in the periplasm of M. A rational basis for the use of combined heparin/aspirin and IVIG immunotherapy in the treatment of recurrent IVF failure associated with antiphospholipid antibodies. The purpose of this study was to review the characteristics of patients who were admitted with chest pain, to evaluate the appropriateness of admissions and the outcomes. We assessed the in utero and neonatal role of two key regulators of pancreatic insulin secretion by studying birthweight and the incidence of neonatal hypoglycaemia in patients with heterozygous mutations in the maturity-onset diabetes of the young (MODY) genes HNF4A (encoding HNF-4alpha) and HNF1A/TCF1 (encoding HNF-1alpha), and the effect of pancreatic deletion of Hnf4a on foetal and neonatal insulin secretion in mice. The results correlated well with those of another assay performed in a separate laboratory.

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In this study, several antiparasitic drugs were studied in Gallotia caesaris (Lacertida) from La Gomera, the Canary Islands, Spain. Acetylcholine injected into the sinus node artery affected the lower left atrium whereas no microspheres could be found in this region upon microscopic examination. The interaction of hCG with rat adipose tissue: apparent lack of hCG--LH receptors. Rheumatic diseases in a medical center for construction and utility workers

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cDNA constructs for wild-type and coding alleles of CYP26A1 were constructed in a pcDNA3.1 expression vector and expressed in Cos-1 cells. A fundamental system of cellular energy homeostasis regulated by PGC-1alpha. Magnetic resonance imaging of the hypothalamic-neurohypophyseal system. Spinal stabilisation in Duchenne muscular dystrophy does not alter the decline in pulmonary function, nor does it improve survival. Detection of cytokine mRNA-expressing cells in peripheral blood of patients with IgA nephropathy using non-radioactive in situ hybridization.

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GONGYLONEMA PULCHRUM MOLIN, 1857, FROM SLAUGHTERHOUSE ANIMALS FROM THE LUBLIN REGION The antiproliferative and apoptotic effects of 17beta-estradiol alone or in combination with Nkx3.1 were estimated on PC3 cells by using MTT growth tests and flow cytometric analyses. This study will attempt to test the predictive validity of these models based on the clinical observations that antipsychotics are not fully effective until after 2-3 weeks of administration in patients and that patients do not relapse immediately following abrupt withdrawal of medication. Old male rats had similar micturition frequencies during the light and dark cycles, in contrast to females and young males, where the number of micturitions during the dark cycle was significantly greater than those during the light cycle. This is shown by some isodose distribution charts (fixed field-, box-, multiple field- and rotation-technique, AL-treatment).

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A number of pyruvic acid and methylpyruvate alpha-(N)-heterocyclic hydrazones has been synthesized. Study of the epiphysis: behavior of blood proteins and of the electrophoretic picture of the blood in rabbits treated with watery pineal extracts In contrast, some WD haplotypes were identified in more than one group. It occurs at all ages and locations but has a preference for the extremities and the retroperitoneum. To test this hypothesis, circulating EPC and EPC-derived endothelial cell colony formation of individuals with asthma or allergic rhinitis and health controls was evaluated.

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Effect of thyro-parathyroidectomy of the development of primary phenomena in the uterus following estrogen stimulation Candida albicans septic thrombosis of the right atrium is associated with a central venous catheter. The NSPs generated similar, relatively stable, disulfide cross-linked immunoreactive fragments of approximately 35 kDa (reduced), and sequencing of a major catheptic fragment definitively localized the major sites of cleavage to a highly conserved subregion of the carbohydrate recognition domain. The advent of customized component corneal transplantation techniques may allow the use of 1 donor cornea to treat multiple patients. Selective T-cell costimulation modulation: a new approach to treating rheumatoid arthritis.

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Rural-urban differences in hospitalization rates of primary care patients with depression. We searched the Cochrane Central Register of Controlled Trials (Central), MEDLINE, EMBASE, BIOSIS, CINAHL, HEALTHSTAR, Current Controlled Trials and reference lists.

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New methods of diagnosis of ventilation disorders and of monitoring are regarded as promising. The type of definitive surgery is dependent of the degree of instability of the anterior and posterior pelvic ring.

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Although it contains only 25 amino acid residues, omega-conotoxin MVIIA folds into a well-defined three-dimensional structure that is stabilized by 3 disulfide bonds. The results suggest that the neutralizing activity of mMCA is inhibited more by anti-idiotypic than by anti-isotypic antibodies against mMCA. Despite intensifying research, the etiology of fibromyalgia has remained unclear.

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Here we describe evidence that sperm also promote egg laying, the release of embryos from the uterus. Although, in this condition, fibrosis may develop in several organs, there have been few reports of fibrosis involving the lung or pleura. This study was designed to evaluate the relationship between minor trauma and surgical results of cervical ossification of the posterior longitudinal ligament (OPLL), focusing on static compressive and dynamic factors contributing to cord compression plus the type of attendant OPLL. Screening of an E.coli genomic library revealed a potential interaction between UvrD and MutL, a component of the methyl-directed mismatch repair pathway. The designer cytokine hyper-interleukin-6 is a potent activator of STAT3-dependent gene transcription in vivo and in vitro.

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We report a sixth case of carcinoid tumor arising in a tailgut cyst. The high SO2 deposition at the northern Illinois location is a consequence of the higher air concentrations observed there. The average amplitude of the agonal inward currents in VH neurons was significantly bigger than that of DH neurons. A clinical comparison between our patient and previously reported AMS cases aids in delineating the adult phenotype of AMS and further broadens the clinical spectrum of this condition. A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity.

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Specific protein-protein interactions between alpha-NAC/1.9.2 and GAL4/VP-16 were demonstrated by gel retardation, affinity chromatography, and protein blotting assays, while interactions with TATA box-binding protein (TBP) were detected by immunoprecipitation, affinity chromatography, and protein blotting assays. Detection of amphiregulin and Cripto-1 in mammary tumors from transgenic mice.

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These large spontaneous fluctuations (up to 0.75 log), observed daily, weekly, and monthly, raise doubt about the clinical value of a single assessment of pretherapeutic viremia. Although natural CDs have been used extensively to improve pharmaceutical properties, the effects of chemically modified CDs on the solubility, dissolution rate, and stability of drugs are overproportional. Interaction of acetylcholinesterase inhibitor donepezil with ionic channels of the neuronal membrane. FISH analysis in patients with clinical diagnosis of Williams syndrome.

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Thus, the data obtained from the present study indicate that the IgM-like protein is an anti-idiotypic antibody against the anti-CA125 monoclonal antibody (OC125). Characterization of in vitro and in vivo mutations in non-conserved nucleotides in the ribosomal RNA recognition domain for the ribotoxins ricin and sarcin and the translation elongation factors.

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This explains why organoleptic and gas chromatographic diagnosis scores better than a portable sulfide monitor. Data on facial nerve stimulation rates postoperatively were collected. Single-nucleotide polymorphisms and lung disease: clinical implications.

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In both isthmic spondylolysis and control groups, considerable shifts were noticed from sagittally oriented articular facets at L1 to frontally oriented facets at L5. 39 patients with chronic wrist pain underwent arthrography and arthroscopy to reveal disruptions of the triangular fibrocartilage complex (TFCC) and/or interosseous ligaments. Atrial fibrillation in endomyocardial fibrosis is a marker of worse prognosis. Except that beagles had no melanocytes in epidermis, there was no essential difference in ultrastructural characteristics of epidermis between hairless dogs and beagles.

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A morphologic study based on computer-assisted three-dimensional reconstructions. Additionally, male RBCs were found to have higher mechanical fragility. This difference was less pronounced in the 12- and 24-week animals.

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In patients presenting symptoms with a suspicion of ehrlichiosis we determined antiehrlichia antibodies and investigated the presence of Ehrlichia nucleic acid in the plasma. sordellii by 3 methods (culture, fluorescent antibody test, and immunohistochemistry) and on gross and histopathologic findings. A number of risk factors are now known, but the etiology of the disease is not fully understood. Wild-type cytochrome b562 and seven variants, displaying a range of intracellular expression levels, were purified. Role of non-adrenergic non-cholinergic inhibitory nerves in the colon of patients with ulcerative colitis.

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Neoblasts that pass through S-phase led to a maximum of mitoses after 48 hr. Some of these microbial differences could have clinical significance. These observations indicate that major matrix changes occur at the same time in male and female first rib cartilages.

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RNA4-encoded p31 of beet necrotic yellow vein virus is involved in efficient vector transmission, symptom severity and silencing suppression in roots. In 2001-2002, adolescents from the Child Development Supplement of the Panel Study of Income Dynamics completed 24-hour time diaries on a random weekday and weekend. To assess the impact of a reoperation due to a regrowth of a pituitary macroadenoma on mortality, taking into account other candidate prognostic factors.

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Despite excellent locoregional control, freedom from recurrence, and overall survival proved disappointing reflecting the frequency of distant metastases. In turn, PGE2 directly acts on GnRH neurons to stimulate the release of GnRH. Diabetes produces dramatic changes in retinal microvasculature, triggering endothelial cell proliferation and microaneurysms.

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Increased abundance of proteins involved in phytosiderophore production in boron-tolerant barley. Aromatase P450-containing cells in the medial preoptico-amygdaloid region, which were devoid of Ad4BP, persisted even in the brain of the gene disrupted mice. ACTIVITY ON URINARY ELECTROLYTES OF VARIOUS TRIAMTERENE AND HYDROCHLOROTHIAZIDE ASSOCIATIONS Novel GUS expression patterns following transposition of an enhancer trap Ds element in Arabidopsis. This paper presents a model of continuous exposure to 226Ra by water consumption over a 55-year period.

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Regulation of chloroplast phosphoribulokinase by the ferredoxin/thioredoxin system. FMD constitutes a recent modification of the standard denaturing gradient gel electrophoresis (DGGE) technique, which combines multiplex PCR amplification of target DNA using fluorescently labeled primers with DGGE separation of the amplicon mixture, allowing immediate identification of sequence variants by wet gel scanning.

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Glucocorticoid receptor expression in the postnatal rat cochlea. This should alert the pediatrician, since most tuberculosis infections in childhood start with contacts of infected adults with children. The overall objective of this study was to evaluate whether data from available U.S.

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Immunoreactivity for mGluR2/3 and mGluR5 as observed in fibers and putative axonal processes in the interstitial, intermediate, and dorsolateral subnuclei of the NTS. Mutual stimulation of oncornavirus and herpetic infections in experiments in vivo and in vitro When NH4(99)TcO4, which cannot go through the blood-brain barrier, was injected into rats 4 d after treatment with 6-OHDA, 99Tc was concentrated in the ipsilateral substantia nigra 30 min after 99Tc injection, but no longer detectable 6 d after injection.