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Because FASN is an androgen regulated gene in the prostate, we have examined the effects of dutasteride on FASN in prostate cancer cells in vitro. The cells were either harvested and assayed for caspase-3 activity or stained with either AE5 or antivimentin antibodies. Combined therapy of somatostatin analogues and dopamine agonists in the treatment of pituitary tumours. Glutathione protection against gentamicin ototoxicity depends on nutritional status.

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Development of neutralizing antibodies did not abrogate the induction of MxA mRNA, but in 3 patients with high antibody titres the antitumor effect was lost. Neonates admitted at the NICU of the Dipartimento Materno-Infantile, University Hospital, Palermo, Italy, from January 7, 2003, to January 6, 2004, were included in the study.

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Effects of nutrient fortified complementary food supplements on growth of infants and young children in poor rural area in Gansu Province Other taste-based behaviors are less affected or not influenced at all. Repopulation of circulating T, B and NK lymphocytes following bone marrow and blood stem cell transplantation. MuLV that would patently infect fibroblasts of BALB/c origin but not those from NIH Swiss mice.

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Persistent high cortisol responses to repeated psychological stress in a subpopulation of healthy men. Its gene sequence identified it as an alternatively spliced human homolog of the Drosophila dorsal-ventral patterning tolloid gene and suggested that it activates transforming growth factor-beta-like molecules by proteolytic cleavage.

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To estimate the disagreement between the histologic reports at colposcopically directed punch biopsy of the cervix and subsequent loop excision of the transformation zone, and to assess the indications for loop excision in current practice. Moreover, we provide evidence that these truncated forms are secreted and able to activate LIN-12 and GLP-1 ectopically. Human placental trophoblast expresses as unusual repertoire of major histocompatibility complex (MHC) class I products that appears to reflect the unique role of this epithelium in mediating feto-maternal relations during pregnancy. Establishment of an entangled atom-field state in the Jaynes-Cummings model. Although subjects with OM histories reported more auditory disabilities in adulthood, there were no significant differences in binaural performance between OM history subjects and controls.

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The action of TNFalpha on preadipocytes can be modulated by the production of endogenous PGs through the induction of COX-2. Low-energy positron collisions with H2 and N2 molecules by using a parameter-free positron-correlation-polarization potential. An aerobic methylotrophic bacterium, Methylobacterium extorquens AM1, was found to contain a cluster of genes that are predicted to encode some of these enzymes and was shown to contain two of the enzyme activities and one of the methanogenic coenzymes. Specific and artifactual labeling in the rat spinal cord and medulla after injection of monosynaptic retrograde tracers into the diaphragm. We also found that synthesis of Bcl-3, which occurs via a specialized translation control pathway regulated by mammalian target of rapamycin (mTOR), is induced when platelets adhere to immobilized fibrinogen in the absence of thrombin and when integrin alphaIIbbeta3 is engaged by a conformation-altering antibody against integrin alphaIIbbeta3.

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Mechanical comparison of an interlocking nail locked with conventional bolts to extended bolts connected with a type-IA external skeletal fixator in a tibial fracture model. We identified three new elements of the Yop virulon: SycN, required for normal secretion of YopN, and YscX and YscY, two new components of the secretion machinery. Disease severity was assessed using the Kellgren-Lawrence (K-L) grade and medial joint space width.

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From our own studies on sheep we have evidence that maternal undernutrition during the periconceptional period results in altered fetal hypothalamic-pituitary-adrenal axis (HPAA) development, an increased rate of premature birth, altered fetal pancreatic function, insulin signalling and amino acid metabolism, and also alterations in maternal adaptation to pregnancy. The mean inclination angle of the humerus head decreased from 178 degrees (170 degrees -200 degrees ) to 134 degrees (130 degrees -145 degrees ) postoperatively. This is likely to be explained by better access to prophylactic regimens and antiretroviral therapy. The extralong pedicle with good-sized vessels makes free-flap transfer safe.

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Here we propose a simple remedy for this undesirable property and show rigorously that the error-free capacity of our oscillatory, associative-memory networks can be made as high as that of the Hopfield network. stewartii, in contrast to most other described systems, uses EsaR to repress EPS synthesis at low cell density, and that derepression requires micromolar amounts of AHL. Many of these symptoms may be the sole presentations of GER in these patients. Lymphocyte subsets, apoptosis, and cytokines in patients with chronic fatigue syndrome. It is found that the total binding constant for esterified derivative is several times as much as that of palmitic acid.

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We conclude that QoL in HF remains an open field, in which new therapies but also clarification of methodology is required. Importance of phlebography in the diagnosis and treatment of recurrent varices Before puberty, follicle stimulating hormone is the primary stimulus for Sertoli cell secretory function, although androgens also participate synergistically. Evaluation the nonlinear response function of a 3 x 3 in NaI scintillation detector for PGNAA applications. It is concluded that the volume change method should be followed for recording oxygen uptake by Warburg apparatus and pure oxygen should not be used as a gaseous medium.

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We conclude that the polarized Th2 response induced by this enteric infection plays a central role in determining whether or not systemic tolerance is induced. A comparison of stereopsis with ANVIS and F4949 night vision goggles. The yeast overexpressing Cu, Zn- SOD appeared to be more resistant to oxidative stress such as paraquat, menadione, and heat shock.

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Leaflet escape is a rare but serious complication of heart valve replacement therapy with mechanical heart valves. The result showed that introduction of wt-p53 greatly suppressed in vitro cellular growth of the laryngocarcinoma cell line and identified that the wt-p53 gene mediated the process of cell apoptosis. Two of the 23 patients had a Ross 14-F Flexi-flo gastrostomy tube which required a retrograde technique due to a small caliber esophagus in these children. Some time between 8 and 16 weeks old the minimum sleeping rectal temperature decreased abruptly from around 36.8 degrees C to around 36.4 degrees C.

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However, a population-based case-control analysis indicated that there was an association between Trp460 allele and hypertension, with a relative risk for subjects carrying at least one Trp460 allele of approximately 1.6. Optimal design of experiments with anticipated pattern of missing observations.

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The aim of this study was to determine the importance of the RLSh magnitude as a risk factor for stroke in nonselected patients. Interferon (IFN) alpha treatment resulted in greater reduction of genotype 2a HCV levels than genotype 1a, as seen in clinical practice. Significance of the surface of crystalline silicogenic dusts in experimental silicosis.

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Diagnosis and treatment of retroperitoneal hematoma in multiple trauma patients. The results thus provide further evidence that M2 regulates transmembrane pH gradients in the trans Golgi.

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Work-related electrocutions involving portable power tools and appliances. Regulation of the parathyroid hormone gene by calcium, phosphate and 1,25-dihydroxyvitamin D. Inhibition of phosphofructokinase by fructose 1,6-diphosphatase in mammalian systems: protein-protein interaction or fructose 1,6-diphosphate trapping?

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Random amplified polymorphic DNA (RAPD) analysis of individual Trichinella muscle larvae, collected from several sylvatic and domestic animals in Estonia, revealed concurrent infection of a racoon dog with Trichinella nativa and Trichinella britovi. Compared with normative data, there was no significant listhesis for the L5/S1 segment.

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Little is known about the natural history of cytomegalovirus (CMV) optic neuritis in the acquired immunodeficiency syndrome. To describe the ocular surface injury resulting from a microwave superheated liquid. Similarity in time of onset, histochemistry, and site of metastasis. Average surgery time for the second toe-metatarsal bone transplantation was 8 hr. Growth stunting in early life in relation to the onset of the childhood component of growth.

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Sucralfate is known to protect gastric mucosa against the damaging action of strong irritants and to accelerate healing of chronic ulcers, but the mechanisms underlying these effects have not been elucidated. A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis.

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Seven to eight minutes after induction of anesthesia, convulsion was observed first on his lower limbs and then on his all limbs and the head. The rates of 22 malformations occurring in the maternity of the University of Chile Clinical Hospital and other Chilean hospitals participating in the Latin American Collaborative Study of Congenital Malformations (ECLAMC) were compared before and after the start of flour folic acid fortification.

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The authors give an account of the incidence and prognosis of the mentioned injuries treated during the past five years (1987-1991) at the surgical department of a district hospital in the centre of Prague. Peri-implantation mouse embryos synthesize insulinlike growth factor (IGF)-II ligand, insulin receptor, IGF-I receptor, and IGF-II receptor and respond to IGF-II, IGF-I, and insulin metabolically and mitogenically. Ten months after the combination therapy thrombocytopenia developed and cytogenetic analysis showed 45,XX,-7, indicating an evolution to myelodysplastic syndrome (MDS) associated with monosomy 7.G-CSF and EPO treatment together with immunosuppression may be an effective therapy in SAA patients, but such a therapy may increase the risk of evolution to MDS.

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The Delta locus in Drosophila virilis: alleles, wing phenotypes and genetic interactions The interaction of transportin with Nup153 could be disrupted by a non-hydrolyzable form of GTP or by a GTPase-deficient mutant of Ran, and was not observed if transportin carried cargo. MPMRA images, acquired in just 2-4 seconds per image, had a blood/tissue contrast-to-noise ratio nearly twice that of standard 2D time-of-flight MR angiograms, acquired in 5-7 seconds.

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The possibility that sequences or structures in this region contributed to a hotspot for RNA recombination was examined. Use and effectiveness of psychological self-care strategies for interstitial cystitis. The dose effect relationship was linear quadratic at all the post-treatment time periods studied. The overall reduction ranges from about 10(3), observed for a member of the family of Papovaviridae, to more than 10(12) for members of the families of Herpesviridae and Orthomyxoviridae.

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A cell-free model of the encephalomyocarditis virus-induced inhibition of host cell protein synthesis. However, the direct benefits of this possible reshaping on LV function in the absence of underlying MR remain incompletely understood. Whether this is also true in COPD with acute respiratory failure (ARF) has not been studied. Modelling the dynamics of LCMV infection in mice: conventional and exhaustive CTL responses. Recent studies performed in the supraoptic nucleus of lactating and chronically dehydrated animals, in conditions where astrocytic coverage of neurones is reduced, have revealed a significant impairment of glutamate clearance.

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Improvements in MRI techniques widen the indications for fetal brain imaging and fetal brain injury represents the third indication of fetal brain magnetic resonance imaging (MRI) after the evaluation of suspected central nervous system (CNS) malformations and ventricular dilatation. Numerous studies have explored reliable variables that predict student success in dental hygiene programs and on the National Board Dental Hygiene Examination (NBDHE). Thermal and conformational stability of Ssh10b protein from archaeon Sulfolobus shibattae. Gene expression of isoformic enzymes in arachidonate cyclooxygenase pathway and the regulation by tumor necrosis factor alpha during life cycle of adipocytes. The following order of relative inhibitory potencies was established: adenosine greater than cAMP greater than db-cAMP.