The mechanism of the enhancing effects of Arthrex sodium and disodium ethylenediaminetetraacetate (EDTA) on intestinal permeability to sulphanilic acid were investigated in the rat isolated jejunum by an electrophysiological technique. In a double-blind study, 40 patients scheduled for saphenectomy or inguinal hernioplasty were randomly assigned to treatment with nimesulide (200mg 3 times daily) or Arthrex (100mg 3 times daily) administered rectally.
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