Atocor is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins. " It works by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks. In addition to eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking. Consult your doctor for more details.

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The effects of the desorbing solvent composition, in this case a mixture of methanol and water, and of flow rate, are evaluated. Results from COX-1 and COX-2 silencing and selective inhibition showed that both COX-1 and COX-2 were involved in the biosynthesis of PGE(2) and their relative contribution depended on the time of incubation with IL-1beta.

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Moreover the causes and the prevalence of unwanted side-effects are discussed. These results justify the conclusion that THVs are members of the subfamily Betaherpes-virinae.

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The aim of this study was to assess and compare the diagnostic quality of polyps obtained using the hot biopsy and cold biopsy techniques. These findings demonstrate that it was impossible to completely eliminate the patches using methylazoxymethanol injections during the period of patch neurogenesis. To determine complication rates for aspirin, warfarin, and intravenous heparin administered for secondary stroke prevention after first episodes of ischemic stroke, transient ischemic attack, or amaurosis fugax in a community. The inter-coherence reduction suggests a spatial inter-electrode dependence during the task, rather than a neuronal specialization. Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements.

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24 children aged 0.6-16 years with chronic active or chronic persistent hepatitis B were included in the study. Abnormalities of chromosome 16q in myeloid malignancy: 14 new cases and a review of the literature.

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However, as a result of the derived toxic effects of these oxidative processes, antioxidants molecules appeared in the very early stages of the evolution and they are able to control the production of these reactants and their dangerous effects. Two-week-old diabetic rats have decreased renal type I IP3R protein and mRNA levels.

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Use of double ventricular extrastimulation to determine the preexcitation index in atrioventricular nodal reentrant tachycardia. We studied its action on eukaryotic cells, with the long-term goal of understanding the pathophysiology of the disease.

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Two patients presented rhabdomyolysis due to drug abuse, one due to intense exercise and the last one due to long unconsciousness with compression of the paravertebral musculature. 2: Flammable liquid, disinfectants and cleansing media, cytostatics, pressurized gases, liquid nitrogen, narcotic gases, mailing of diagnostic samples, hazardous waste Direct HIV cytopathicity cannot account for CD4 decline in AIDS in the presence of homeostasis: a worst-case dynamic analysis. elegans, mab-5 also acts in P8.p specification, but mab-5 mutant animals do not develop differs between species, indicating that alterations in the intrinsic properties of P8.p and corresponding changes in the functional specificity of mab-5 have occurred during evolution. Another mutation which increases the affinity of Rad51 for DNA was also found to increase gene repair when overexpressed in the cell.

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To determine if DNA quantification, studied in cytologic samples obtained by fiberendoscopy, has predictive value in gastric adenocarcinoma. The amygdala and hippocampal complex, two medial temporal lobe structures, are linked to two independent memory systems, each with unique characteristic functions. Research is needed to evaluate whether it is more effective than standard clinical interventions for tobacco use cessation. Investigation of the regioselectivity for the staudinger reaction and its application for the synthesis of aminoglycosides with N-1 modification.

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For preventing or treating intracardiac thrombi and emboli, antithrombic drugs may be used in large heart dilations, atrial fibrillations, ventricular aneurysms, dilated cardiomyopathies and patients with embolic history. Single cell oil sources of docosahexaenoic acid: clinical studies. Amelioration of hot flashes may reduce some complaints of poor sleep but will not necessarily alleviate underlying primary sleep disorders. In most cases, conventional radiographs provide sufficient information. Acute liver failure caused by isoniazid in a child receiving carbamazepine.

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Because the structural transition is described by very few parameters, over-fitting of real experimental data is easily detected by using a cross-validation test. The vulnerability of developing oligodendroglia to Oct-6 deregulation provides evidence that the POU factor may play a direct role in myelin disease pathogenesis in the mammalian CNS.

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The aim of this article is to illustrate, through a specific example, the quality of DI as a simple procedure for assessing breastfeeding trends. The need to quantify right-to-left shunt in acute ischemic stroke: a case-control study. Previous studies have demonstrated that the third domain of FcgammaRI plays a crucial role in high affinity IgG binding of the receptor, with the first and second domains together forming a low affinity IgG binding motif.

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The major piroplasm surface protein (MPSP), a conserved protein in all Theileria species, has been used as a maker for epidemiological and phylogenetical studies of benign Theileria species. Temnothorax albipennis colonies use a sophisticated strategy to select a new nest when the need arises. The secretion pattern of putuitary growth hormone (GH) in rodents is sexually dimorphic and regulates the expression of some hepatic genes. 1 Investigations were made into the effects of prostaglandin E(2) (PGE(2)) and a prostaglandin endoperoxide analogue (Upjohn compound U-46619) on the responses of the rat anococcygeus muscle to field stimulation of the intrinsic sympathetic nerves, and to exogenous noradrenaline.

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Macrophage stimulation using a group B-streptococcus exotoxin (CM101) leads to axonal regrowth in the injured optic nerve. The compound proved to be superior to the reference drugs in the rate and duration of antiarrhythmic and antifibrillatory action. In most cases they can be solved in case-focussed team conferences. Rotavirus is the most common cause of acute childhood gastroenteritis. Disruption of primary sensory afferents by mechanical (deafferentation by dorsal rhizotomy) or chemical (exposure to the primary afferent neurotoxin, capsaicin) methods virtually abolished endomorphin-2-like immunoreactivity in the dorsal horn.

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In patients with severe pulmonary congestion and oedema, combined use of loop diuretics and thiazides may improve the therapeutic response. Fifteen bacterial strains from inflamed and six from noninflamed colonic tissues from IBD patients. Sample volume as high as 1 microL was injected into the WE system and reasonable efficiency was obtained for separation of the test compounds. Although there are several articles describing the light microscopic structure of the organ, the data presented are rather conflicting especially when comparing glomus tumors and normal coccygeal bodies.

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DNA-DNA hybridization with total genomic probes also revealed four major distinctive entities that corresponded to those identified by multilocus enzyme electrophoresis. The pharmacokinetic studies were carried out following administration of 40 mg/kg of racemic HCQ to diabetic, insulin-treated diabetic, adjuvant arthritic and control rats.

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Littoral zooplankton responses to acid and aluminum stress during short-term laboratory bioassays. It is likely that the mortality and morbidity associated with breast cancer motivates this increased use.

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Within the superior olive, choline acetyltransferase (ChAT) was expressed differentially. Women randomised to screen-and-treat received appropriate antibiotics only if screening proved positive for one or more infection. Lewis (RT.1(l)) rats were injected subcutaneously with heat-killed Mycobacterium tuberculosis H37Ra to induce AIA. Analysis by polymerase chain reaction showed that the granule cells in culture expressed predominantly the B0 isoform of agrin mRNA. Microsurgical anastomoses and nerve coaptation continue to be challenges in free muscle transplantation.

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Analysis of combined data from the treatment and placebo arms of a large, negative, sepsis trial. Morbidity and mortality have been reduced by improvements in management, including screening programmes, non-invasive ultrasound evaluation and invasive procedures. It is found that a degree of periodontal atrophy strongly and directly correlates with the age of rats. For the calculation of changes in oxyhaemoglobin, deoxyhaemoglobin and the redox state of cytochrome-c-oxidase from attenuation data via a modified Beer-Lambert equation the wavelength dependence of the differential pathlength factor (DPF(lambda)) has to be taken into account.

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High-molecular-weight substances such as proteins can pass the epidermis only if it is damaged and cause a sensitization. A sample of (15)N-delta 1-L-histidine lyophilized from a solution of pH 6.3 and a (15)N-delta 1-L-His labeled transmembrane helical peptide in hydrated lipid bilayers were used to illustrate the advantages of this scheme.

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To establish whether 24 h urinary excretion of the potent vasodilator calcitonin gene-related peptide (CGRP) was higher in postmenopausal women with vasomotor symptoms compared to the level in women without symptoms. The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors. The results are compared with those already published in the literature.

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Why children die: an under-5 health care survey in Mafikeng region. The scan time has been reduced 16- to 64-fold from previous techniques. The liquid structure of the LA/PPA mixture was clarified through the SAXS and also the SANS measurements.

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Estrogen acts in the brain to regulate female reproductive physiology and behavior, and protein kinase C (PKC) is estrogen-regulated in many estrogen-responsive tissues. Researchers and journal editors do a disservice to the interests of the public and others involved in healthcare decision-making by acquiescing in this situation. Childhood depression, anxiety, and aggression: a reanalysis of Epkins and Meyers (1994). The fourth, HIV-27924A, obtained from a patient with AIDS, was xR4-tropic.

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Safety was assessed by comparing adverse event profiles between anakinra and placebo patients according to concomitant medications received. Resonance profiles for electron-ion photorecombination at an isolated resonance.

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Physical changes in the epsilon prototoxin molecule of Clostridium perfringens during enzymatic activation. This sample was statistically compared with a numerically identical standard sample, selected at random. We have isolated and characterised three candidate genes for controlling limb identity in the chick.

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The American Optometric Association has taken steps to address the challenge of increasing the pool of qualified applicants to the schools and colleges of optometry. Dietary factors appear to be associated with onset of menopause. Mechanical circulatory support as a bridge to heart transplantation: what remains? Residential and occupational exposures to 50-Hz magnetic fields and breast cancer in women: a population-based study.

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Many glomerular diseases are associated with mesangial cell proliferation and the accumulation of extracellular matrix. Such defects may cause reflexive overproduction of TNF and other pro-apoptotic cytokines. Specific patient characteristics and potential risk factors, of which less is known, may influence treatment decisions. Characterization and regulation of adenosine transport in T84 intestinal epithelial cells. Better knowledge of the disease and of evolving diagnostics can enable recognition of unusual manifestations.

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Abnormalities of thickness may be seen in the internal sphincters and defects in both. Concurrent administration of phenobarbital with disulfiram or diethyldithiocarbamate led to potentiation or antagonism of the primary effects of each compound when given alone. We have studied gluconeogenesis and glycolysis pathways in intact hepatocytes isolated from fasted rats submitted to 24 h of hypoxic in vivo exposure.

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Portal hypertension, testicular atrophy and arthropathy were not improved. The protocol describes the isolation of mitochondria from animal tissue, initial establishment and optimization of the oxygen consumption assay, subsequent screening of compounds for mitochondrial toxicity (uncoupling and inhibition), data analysis and generation of dose-response curves. No beneficial effect of the universal leukocyte reduction in cardiac surgery was found for culture-positive infection rates, 90-day mortality, or length of intensive care stay.

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Antibodies against nucleotide-peptides of beef heart do crossreact with nucleotide-peptides of other beef organs, but with nucleotide-peptides of Ehrlich tumor cells. Nucleoside diphosphate kinase (Ndk) is an important enzyme that generates nucleoside triphosphates (NTPs) or their deoxy derivatives by terminal phosphotransfer from an NTP such as ATP or GTP to any nucleoside diphosphate or its deoxy derivative. Tyrosinase activity was increased 2.2 fold after 16 hours of incubation with 10 microM paclitaxel. The time of appearance and distribution of substance P (SP)-like immunoreactivity in the granular convoluted tubule cells of the developing male mouse submandibular glands were examined, and the subcellular localization of SP-like immunoreactivity was investiagted by electron microscopy. However, BXL-628 did not inhibit 5 alpha-reductase 1 and 2, did not bind to the androgen receptor (AR) in BPH homogenates and did not affect AR-coupled luciferase activity.

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Behavioral/psychoeducational group training in therapy for overtaxed men. Comparison of Asian and English non-attenders at a hospital outpatient department.

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Purified Gln506-FVa, generated either by thrombin or by FXa, was resistant to APC. A commercial service provided all newspaper clippings reporting unintentional injury events between July and September 1995 from 17 daily and 55 weekly newspapers published in Connecticut, USA.

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The Falant grades the severity of color deficiency and identifies subjects with different types of deficiency. Cholesterol absorption was accompanied by cholesterol esterification and secretion. The actin cytoskeletal network was visualized by phalloidin staining. By combined column affinity chromatography and preparative electrophoresis, a lipoprotein was isolated from the electrophoretically defined pre-alpha-region.

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In the presence of TPA, the release of IR-ET-1 from the cells was higher than the control level for up to 8 h, but was lower thereafter and reached a plateau after 48 h. Interactions with the GalNAc predominate in the binding of the disaccharide. We studied HCA concentration in relation to preparation habits among 63 volunteers. They received wound infiltration at the end of surgery and through an intraarticular catheter 24 h postoperatively.

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Stage I non-small cell lung cancer: results for surgery in a patterns-of-care study in Sydney and for high-dose concurrent end-phase boost accelerated radiotherapy. Immunosuppressive effect of paracoccidioidomycosis sera on the proliferative response of normal mononuclear cells. On the bioavailability of methyl isocyanate in the Bhopal gas leak. This article categorizes the various lateral skull-base approaches, outlines the principles of the surgical exposures, and discusses the indications for their use. The interferon regulatory factor 7 (IRF-7), a member of the IRF family of transcription factors, is a key player in the innate immune response against viral infections.

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Poly (ADP-ribose) polymerase, a nuclear protein-modifying enzyme, binds to the internucleosomal linker region of chromatin, although it modifies certain core nucleosomal histones in addition to histone H1. This chapter describes a retroviral insertion mutagenesis approach using replication-deficient myeloproliferative sarcoma virus retroviral vectors to identify apoptosis regulatory genes in the interleukin-3-dependent Baf-3 cell line. Preterm and term infants have a similar decline in antibody titers during the first 3 years, but preterm infants generally have a lower titer.