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This low level of neutering accounted for the finding that 69 and 78 per cent of the entire bitches and queens had had litters in the 12 months preceding the survey. Immunocytochemical ABC method was performed in cell suspension, the specific antiserum (1:200 diluted) was rabbit anti-human CGRP. Music therapy is widely used in the treatment of acute and chronic pain. However, through careful clinical observation we now believe that the only abnormality present is herniation of breast tissue through the nipple-areola complex.

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Enhanced p38 activity in DS and DM rats was not associated with increases in expression of active mitogen-activated protein kinase 3/6, an activator of p38, but paralleled with increased expression of scaffolding protein transforming growth factor-beta-activated protein kinase 1-binding protein 1. None of the previously reported degradation products, such as the epi- and anhydro-compounds, were detected as the final degradation products. This may be explained by the difficulty in making an early diagnosis of this problem, at a time when therapeutic intervention may be more effective, and, on the other hand, the lack of a well-established prevention and treatment approach for patients with VOD. The incident reporting system does not detect adverse drug events: a problem for quality improvement. Local injection of cisplatin for vaginal stump recurrence of gynecological malignant tumor

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The authors formulate a Car-Parrinello treatment for the density-functional-based tight-binding method with and without self-consistent charge corrections. Tooth movement velocities from 0 to 1 week and from 1 to 2 weeks after the corticotomies were significantly faster on the experimental side than on the sham side. Enhanced capillary formation stimulated by a chimeric vascular endothelial growth factor/vascular endothelial growth factor-C silk domain fusion protein.

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there is a 72-kD constitutive form, a 64-kD form that may have appeared during evolution of C4 metabolism, and a 62-kD form that is necessary for the complete functioning of C4 photosynthesis. The HSS method extracted the heterochromatin region, suggesting that it is composed mostly of DNA rich in A-T base pairs.

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We report two cases of transepidermal elimination of elastic fibers after laser resurfacing with the carbon dioxide (CO2) laser for rhytides. Women showed a stronger negative reaction to high wind speed than men. Therefore, molecular cytogenetic analysis of somatic mosaicism is warranted in children with unexplained autism. Selective enhancement of P-type calcium currents by isoproterenol in the rat amygdala.

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This could represent a mechanism by which tobacco smoke is carcinogenic. Immunohistochemical surface marker study revealed both tumors were B cell lymphoma. The higher rate of slow flow in infarct related artery after PCI observed in diabetics can be one of reasons for higher 30 day mortality in this group. The results are explained on the hypothesis that periodic fluctuations occur in Ca concentration inside the presynaptic nerve terminal.

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The ASP receptor C5L2 is regulated by metabolic hormones associated with insulin resistance. Circulating corticotropin releasing factor-like activity in man.

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The presence of the electrode inside the 40 nL microchannel enables the detection of the redox active enzyme substrate directly inside the reaction channel. A previous study documented the presence of mutations in mprF that accompanied the loss of daptomycin susceptibility among Staphylococcus aureus isolates following exposure to the drug. Introduction of adjuncts and their influence on changing results in 402 consecutive thoracoabdominal aortic aneurysm repairs. A total of 357 genes differed significantly in expression between infected and non-infected lung tissue, 713 genes differed in expression in liver tissue from infected versus non-infected animals and 130 genes differed in expression in tracheobronchial lymph node tissue from infected versus non-infected animals.

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Pyramid image representations via tree structures are recognized methods for region-based image analysis. It is suggested that the observed recession of transmission disturbances may be caused by partial adaptation of blockade of the tetanic response, post-tetanic inhibition of twitch blockade of enzymatic hydrolysis of acetylcholine. Fusarium graminearum A 3/5 as a novel host for heterologous protein production. Increasing the ratio of wood to acid caused a steady decline in metal removal. Among these 3 regimens that of isoniazid, rifampicin and pyrazinamide for 2 months, followed by isoniazid and rifampicin twice a week for 4 months had the lowest costs (Baht 1,499).

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Accordingly, Cav-3 expression was further increased during hypertrophy of L6C5 myoblasts treated with Arg(8)-vasopressin and in hypertrophic muscles of MLC/mIGF-1 transgenic mice. The technique of atom probe tomography (APT) is reviewed with an emphasis on illustrating what is possible with the technique both now and in the future. Positive immunoreactivity manifested as diffuse, homogeneous, moderate or strong, cytoplasmic staining, confined to tumor epithelium. The timeline for these experiments varies from 2 days to 2 months. Following infarction, the mast cell density at the subepicardial site of the infarction gradually increased, reaching a maximum of 25 cells per mm2 on day 21, while a non-significant increase was observed at the subendocardial site.

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In high-pH anion-exchange HPLC of the oligosaccharides released from native rFVIIa by hydrazinolysis the major peaks elute as oligosaccharides with 1 or 2 N-acetyl-neuraminic acids. To determine whether ketone bodies sustain neuronal function as energy substrates, we examined the effects of beta-hydroxybutyrate (betaHB) on synaptic transmission and morphological integrity during glucose deprivation in rat hippocampal slices. The effects of alpha 2-adrenoceptor blockade or activation on glucose, insulin, free fatty acids (FFA), and glycerol responses to a mixed meal were studied in the beagle dog.

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Continuity of care and intermediate outcomes of type 2 diabetes mellitus. Previous investigations suggest a crucial role of the pedunculopontine tegmental nucleus (PPTg) in elicitation of cortical EEG alterations during paradoxical sleep. Oncology nurses can significantly influence the quality of care given to patients who develop diarrhea as a symptom of cancer or as a sequela of cancer therapy. Synaptic currents due to transmitter release at sets of synapses, such as those formed by a single nerve terminal on adjacent smooth muscle cells or a nerve terminal on a dendrite, possess different amplitudes and time courses, that is different shapes. A new clustering system for protein sequences and its application to constraints discovery in protein evolution.

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Tryptase, via its proteolytic activity, also potentiated GM-CSF, but not RANTES, release from asthmatic and nonasthmatic ASM cells induced by both cytokines. Thus, the mechanisms required to make high-affinity antibody develop gradually during the first year of life. Human cytomegalovirus protease complexes its substrate recognition sequences in an extended peptide conformation. Except for a significant difference in preoperative FSH-level between both groups, there were no significant differences regarding age, Body Mass Index (BMI), oestradiol (E2) or the percentage of women with vasomotor complaints.

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A process integration approach to industrial water conservation: a case study for a Chinese steel plant. Electron microscopy showed particles similar to those seen previously and some newly described morphologies. Our results indicate that single amino acid mutations in the alpha-catenin binding site of homologs of Armadillo could prevent a stable association with alpha-catenin, thus affecting cadherin-mediated adhesion. Additional MC techniques were developed to focus specifically on the interseed attenuation and tissue effects. A variety of modes of teaching and learning should be used to meet the learning needs of students.

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This study investigated the role of the CD28/B7 (blocked by CTLA4Ig) and CD40/CD40L (blocked by MR1) costimulation pathways on in vivo host T-cell- mediated immune responses to allogeneic hepatocytes. This tumour location is generally non-resectable for cure and, since adjuvant chemotherapy is ineffective, patients die from the tumour thrombus formation causing tumour emboli and metastatic disease to the lungs. The Haemophilus somnus disease complex (Hemophilosis): A review.

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Mutation of a threonine residue to alanine in the conserved amino-terminal regions of Ets1 and Ets2 (threonine 38 and threonine 72, respectively) abrogated the ability of each of these proteins to superactivate reporter gene expression. The large tumor antigen (TAg) of simian virus 40 regulates transcription of the viral genes. DNA was studied by Southern blotting and by the single strand conformation polymorphism (SSCP) protocol to identify mutations. This study investigated the relationship between serum levels of two neurotrophic factors, insulin-like growth factor-1 (IGF-1) and hepatocyte growth factor (HGF), and carotid atherosclerosis and cognitive function in the elderly.

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Influenza pandemic: perception of risk and individual precautions in a general population. Shear bond strength was measured with a universal testing machine. The chapter shows that transgenic mice are a most suitable model for studying various aspects of malignant transformation from the molecular to the organismal and populational levels. Quantitative dependence of structure-antiseizure activity in a series of macrocyclic compounds

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However, in five cases, the markers could not be identified by this assay, most likely because of very low levels of mosaicism and/or their small size and lack of detectable euchromatin. Our findings indicate that Theileria parasite molecules that are transported to the leukocyte nucleus have the potential to modulate the phenotype of infected cells. Transmission and protection in leprosy: indications of the role of mucosal immunity. BALB/c mice were immunized with phosphorylcholine conjugated to keyhole limpet hemocyanin (PC-KLH) and simultaneously treated with 1 microgram recombinant murine IL-12 for 3 consecutive days.

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Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo. Percentage changes from 1997 to 2002 were calculated for PTA and intravascular stent placement procedures. However, problems such as heparin-induced thrombocytopenia, protamine shock, and antithrombin III deficiency exist related to CPB with heparinization. Improved monitoring of rainforests helps pierce haze of deforestation.

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While relatively easy to conceptualize, the stages of melanoma progression are not necessarily discrete, nor are they unambiguously defined at the morphologic or molecular levels. Most respondents attempted to suppress preterm labour for steroid administration and/or transfer. A new hemagglutination method to determine antibodies against Entamoeba histolytica We report here a 36-year-old Arab female with beta-mannosidosis who presented with mental retardation and multiple angiokeratomas. Case management has been suggested as an innovative strategy which facilitates the linking of quality and cost-effective care.

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An endopath subcutaneous dissector was subsequently inserted along the anterior surface of the saphenous vein with the assistance of an endoscope and video monitor. Chicken keratin-19: cloning of cDNA and analysis of expression in the chicken embryonic gut. To meet the growing demand for objective outcomes measurement during treatment of chronic pain, we developed an instrument to track outcomes of individual patients. The systems currently used for grading the severity of neurologic injuries have serious limitations. The complement system was studied prospectively in 29 patients, predominantly renal (25), with systemic lupus erythematosus (SLE) to examine the value of complement assays in the distinction between active and inactive disease.

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Although various periodontal regenerative therapies are used, their effects on non-contained infrabony defects are unpredictable. The influence of primary structure on the consequences of particular amino acid changes was further emphasized by the contrasting effects of the G34E mutation on the activities of two closely related proteins, causing an increase in the activity of the M2 of A/chicken/Germany/27 (Weybridge) as opposed to the decrease in activity of the Rostock protein. Common cancerous specificity of human tumors of various localizations

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Meteors do not break exogenous organic molecules into high yields of diatomics. Differences in stroke volume were calculated as percentage change from the first recording.

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IL-4 locus remodeling is accompanied by demethylation and requires both antigen stimulation and STAT6 activation. Neural tube and craniofacial defects with special emphasis on folate pathway genes. The majority of reported cases occur in conjunction with scimitar syndrome, including hypoplasia of the right lung, anomalous right pulmonary venous return and systemic arterial supply to the lung.

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In pine shoots, total free amino acid concentration and the concentrations of ornithine, lysine, histidine and arginine were significantly negatively correlated with the distance from the pulp mill, while in spruce only the individual amino acids glycine, ornithine, lysine and histidine showed a significant negative correlation with distance. Although the reversed halo sign is relatively specific for cryptogenic organizing pneumonia, we report a case of cellular nonspecific interstitial pneumonia showing this sign on chest HRCT. Salicylic acid dependent signaling promotes basal thermotolerance but is not essential for acquired thermotolerance in Arabidopsis thaliana. Thus, our data provide circumstantial evidence that the lungs of patients with acute respiratory failure might exhibit some relative resistance to prolonged oxygen exposure.

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Further longitudinal studies must examine in depth the possible modes of transmission of the organism in young children. On the west side of the mountain range, a pattern of isolation by distance was detected. The published data regarding this unusual condition are reviewed.

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In addition, as determined by the concurrent microiontophoretic application of flibanserin and 5-HT, flibanserin behaved as a full agonist in the dorsal raphe nucleus (DRN) and the medial prefrontal cortex (mPFC), but as a partial agonist in the CA3 region of the hippocampus. Redundancies of the 2(8) different binary patterns were reduced by two different procedures. Inhibition of fatty acid oxidation has recently emerged as a promising approach to the prevention of these adverse effects of fatty acids. Real-time fMRI of cortico-limbic brain activity during emotional processing. The result is a highly esthetically pleasing restoration that is functional and very conservative compared with traditional crowns.

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Experiments using DNA binding and competition assays showed that the proximal element B (-87/-72) binds strongly, in addition to HNF-4, ARP-1, EAR-2, and EAR-3, heterodimers of RXRalpha with RARalpha, and less efficiently, homodimers of RARalpha and heterodimers of RXRalpha with T3Rbeta or PPARalpha. Progression to type 2 diabetes characterized by moderate then rapid glucose increases. Three of four transgenic families expressing the truncated FGF receptor exhibited lens defects ranging from cataracts to severe microphthalmia.

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The geographic distribution of the A(-6) variant leads to the intriguing hypothesis that the G(-6) promoter variant has been selectively advantageous outside Africa. Evidence for the replication of bovine leukemia virus in the B lymphocytes. We have visualized the redistribution of coronin by fluorescence imaging of motile cells that have been transfected with an expression plasmid containing the coding sequence of coronin fused to the sequence encoding the green fluorescent protein (GFP).

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In contrast, in all the subjects with latent MTrPs, only unilateral motor unit activation could be obtained in the muscle on the same side of the needle stimulation. Sublethal alterations and sustained cell proliferation associated with the diethylstilbestrol-induced renal carcinogenesis in male Syrian golden hamsters. From 96 surgical interventions in the child, the authors studied the repartition of tumours according to their histological nature, their benignity or malignancy. Therapy produced a significant deterioration of carbohydrate tolerance with sequential preparations containing 100 microgram of ethinyl oestradiol or graduated doses of mestranol up to 50 microgram. Thermoacoustic theory is extended to stacks made of random bulk media.

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Four cases of herpes encephalitis treated with dexamethasone and cytarabine. PNAs are DNA mimics that are more sensitive to mismatches than DNA probes, and will not serve as primers for DNA polymerases. The frequency of suctioning, catheter-size, suction pressure and open versus closed systems are discussed.

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In this article, ionic models described in the literature are reviewed and compared, with a view to examining their effectiveness in reproducing known chronotropic responses to vagal stimulation. The presence of diffuse idiopathic skeletal hyperostosis and spondyloarthropathy was also recorded. This was a cross-sectional study of 553 consecutive patients who presented for family medicine well visits. This truncated FGF receptor is thought to act as a dominant negative protein by heterodimerization with endogenous FGF receptors.

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Similar to the effects of gating modifier toxins (hanatoxin and SGTx) on the voltage-gated potassium (Kv) 2.1 channel, APETx1 shifts the voltage-dependence of hERG activation in the positive direction and suppresses its current amplitudes elicited by strong depolarizing pulses that maximally activate the channels. Results from the panel data estimations indicate that the business cycle effect is insignificant on overall rates of incidence, mortality and lethality.

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Nonsteroidal antiinflammatory drugs (NSAIDs) such as indomethacin decrease mucosal PGE(2) production by inhibiting cyclooxygenase (COX) activity and produce damage in the small intestine. Considering that the term homology is essentially a comparative concept, making emphasis on structural correspondences between organs or body parts, I use the term evolutionary, or phylogenetic homology to denote a common evolutionary origin of two characters.

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The medical records of women who received enhanced perinatal services from specially certified Medicaid providers in California were abstracted for information on nutrition risk assessment and outcomes. Despite 13 days of intensive supportive care, the dog was euthanased due to continued haematemesis and anorexia. During the past 30 years, antibiotic prophylaxis has proved of enormous efficacy in reducing the incidence of surgical wound infections, postoperative morbidity and mortality, the duration of the postoperative period, and the overall cost of surgical treatment. Five hours before killing the animals were injected with 5 mg colchicine/kg. Five years after the baseline evaluations, the incidence of cardiovascular disease was assessed by a self-administered questionnaire.

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If pruritus is the most constant symptom of onchocerciasis, hanging groin is usually observed only in hyperendemic areas in association with high microfilarial density. A review of the limited treatments that have been reported to date are also provided in this article. In the case of flavor and aroma constituents, it is not sufficient to depend upon mass spectrometric identifications based solely on comparison with commercial databases. In various situations producing PVCM, multiple system atrophy (MSA) is a representative neurological disease causing nocturnal laryngeal stridor attributed to PVCM. Nurses are optimally prepared to identify the early signs of cardiometabolic risk by testing for and assessing the metabolic syndrome.

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After a 4-year follow-up, there has been no recurrence and no metastasis. In mice these antibodies selectively reduce serum IgE, inhibit antigen induced skin reactions, cytokine production by lung Th2 cells, and pulmonary eosinophil infiltration.

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This should be considered during assessment of clinically normal animals with GSO as they can be a potential reservoir for infection in human beings. Tyrosine-phosphorylated ITIMs allow PIR-B to associate with SHP-1 but not with SHIP. Very good agreement was observed between dielectric and shear relaxation times, and those obtained from the heating rate dependence of the Tg, for dry indomethacin as a function of temperature above Tg. After 45 years of age, the overall frequency of spondylolysis declined, indicating that even complete defects occasionally healed.

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A total of 900 consecutive patients admitted to a UGIH unit between October 1995 and July 1998 were analysed prospectively. An improved high throughput protein-protein interaction assay for nuclear hormone receptors. Nevertheless, synergistic effects by sGnRH and E2 were evident for all three GTH subunit mRNAs. Practical and dogmatic differentiation between benign lesion and malignant lesion Initiated either by thermal injury or mechanical trauma, the systemic inflammatory response syndrome stimulates activation of coagulation and fibrinolysis, evolving into a subclinical disseminated intravascular coagulation.

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Taking into consideration the age of the child, the sexually transmittable agent and the localization of the infection helps in assessing the possibility of sexual abuse. Decreased potency of MDR-modulators under serum conditions determined by a functional assay. However, nutrient composition varies among different plant foods. Application of SELDI-TOF mass spectrometry for the identification of differentially expressed proteins in transformed follicular lymphoma.

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For typical domestic wastewater, which has a relatively high BOD(L)-to-TKN ratio, the step-feed process will outperform the Modified Ludzack-Ettinger process for nitrogen removal, when the flow to each step is optimally distributed. With the progress of imaging technologies such as CT and MR imaging, we can obtain various informations from CT and MR images.

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He underwent a second operation due to mitral regurgitation caused by retraction of the mitral apparatus by the patch scarring. For understanding the local immune response in human non-small cell lung cancer (NSCLC), we investigated both Th1 and Th2-type as well as TGF-beta1 cytokine mRNA expression in 10 fresh tumor biopsies, the corresponding tumor and short term TIL cell lines as well as patient PBMC. It appeared that the immobilized antibodies adsorbed two forms equally well and could not distinguish between them under the conditions used. Melatonin restores and enhances the human type B tonsillar lymphocyte subset in recurrent acute tonsillitis. Interestingly, a large number of neural stem cells, vascular endothelial growth factor-immunopositive cells and new blood vessels were observed only around the region of infarction, and none in the corresponding brain areas of the healthy control.

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Ovaries from breeder mice (BR) or females subjected to incessant ovulation (IO) were compared at 6-, 9- and 12-months of age. Performance of a 7-parameter DLT method for the calibration of stereophotogrammetric systems using 1-D transducers. In this study DC numbers, phenotype and DC responses to the Toll-like receptor (TLR)-3 ligand, poly I:C, were examined in new-onset Type 1 diabetes (T1D) patients (ND) and in established T1D patients (ED). We describe the anesthetic management of a patient with PNH who underwent general anesthesia for cesarean delivery. coli O26:B6), a trigger for thrombosis in septicemic patients, we could not detect an increased TF activity of HUVEC on its surface.