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Calan (Verapamil)

In the younger subjects exercise performance was not changed after Calan ingestion. Prevention of acute cyclosporin nephrotoxicity by Calan and atrial natriuretic factor in the rat. Using either the calcium channel blocker Calan or anti-calmodulin drugs (diazepam, trifluoperazine,) the cytoprotective effect of prostacyclin can be inhibited.

Other names for this medication:
Verapamil, Calan, Calaptin, Isoptin, Verelan,

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Calan is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Calan is called a calcium channel blocker. It works by relaxing blood vessels so blood can flow more easily. It may also lower the heart rate. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat other heart diseases (such as hypertrophic cardiomyopathy, fast/irregular heartbeats) and to prevent chest pain (angina).

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Phytosphingosine-1-phosphate (PhS1P) was found to stimulate an intracellular calcium increase via phospholipase C but not pertussis toxin (PTX)-sensitive G-proteins in L2071 mouse fibroblasts. The PPSS instrument is valid and reliable and the only specific instrument measuring postnatal sense of security that is useful for both parents. The difference in the stroke mortality ratio before versus after adjustment for county provides an estimate of the proportion of the excess stroke mortality inappropriately attributed to race (that is in fact attributable to geographic region). The patient had a markedly deformed and depressed plaque surrounded by erythema on the right cheek.

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In contrast, the tachykinin decreased the rate of alkalinization in rats subjected to elevated intraluminal pressure and treated with indomethacin. Total protein as well as excretion of essential metals (Cu, Zn) with the urine were determined 24 hr after 1, 3 and 7 dosages as well as 3 and 7 days after the termination of administration. Reproducibility of the peritoneal equilibration test in CAPD patients.

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The mother centriole is not a bona fide template but a platform for a set of regulatory molecules that catalyzes and regulates daughter centriole assembly. The newly developed method of SH2D1A mutation analysis may be suitable in the diagnosis of XLP in Chinese. Further studies on the differences in serum dependence in EBV negative lymphoma lines and their in vitro EBV converted, virus-genome carrying sublines. Chromosomal regions specific to pathogenic isolates of Escherichia coli have a phylogenetically clustered distribution. Plasma catecholamines were low and unaffected by either drug, as was the QRS duration.

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Changes were symmetrical and were not restricted to joints with tendon ruptures or fractures in the anamnesis. To determine the value of intramucosal pH for evaluating the effectiveness of treatment for hemorrhagic shock. Comparison of two surgical methods for treatment of crib-biting in horses.

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Applications of organ precursor cell therapy: can lessons from embryonic kidney transplantation be applied to the endocrine pancreas? Mutations affecting at least two different genes have thus been shown to underlie NPC. The MAP kinase activation was inhibited by either the angiotensin AT1 receptor antagonist losartan or the endothelin ETA receptor antagonist BQ 123. Factor analysis of a response probability matrix revealed two orthogonal axes.

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Furthermore, a strong correlation between SIV env-specific MHC-restricted CTL in the LP and protection against colonic mucosal challenge was observed. The effects of aftercare on chronic patients and frail elderly patients when discharged from hospital: a systematic review. Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors.

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It is therefore critical to monitor treatment response, particularly in the immuno-deficient population. Sex and gender differences in lung development and their clinical significance. In contrast, cell division arrest late in G1, at START, was accompanied by a selective downregulation of only the first dolichol pathway gene, ALG7, and not of the genes functioning later in the pathway. Action of histones and nonhistone chromatin proteins on the differentiation of embryonic systems

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The paper draws attention to the importance of rare, but important anatomical variety of nervus laryngeus recurrens, s.c. Staggered endoproteolytic cleavage after adjacent arginine residues 506 and 507 separates the 42 kDa C-terminal subunit containing all the cysteine residues from the serine and threonine rich N-terminal region. A study to determine optimal molar ratios of Protein A to laccase for the synthesis of their conjugate by periodate method is presented. The bioavailability of PAHs for microorganisms, but not for mammals, was shown to be considerably reduced in the presence of high total organic carbon (TOC) values of the soil samples. The results further suggest that future studies of the effects of hibernation on learning and retention of active avoidance tasks employ low-level aversive stimuli.

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Main Outcome Measure Traumatic events and PTS were assessed from child and parent reports annually to 16 years of age. Role of the general physician in a screening strategy for cancer of the cervix uteri Because the proto-oncogene c-myc can modulate apoptosis in response to cytotoxic insults and is commonly overexpressed in pancreatic cancer, we investigated the value of c-myc as a potential modulator of cellular response to various chemotherapeutic agents. Maternal risk factors for testicular cancer: a population-based case-control study (UK). Myocardial ischemia in generalized coronary artery-left ventricular microfistulae.

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During the preventive phase, a partial inhibition of CFRs was induced by ketorolac and aspirin. Guatemala is a nation of 10 million persons, at the northern point of the chain of five Republics derived from Spanish colonies on the Isthmus of Central America. An enzymatic assay for microsomal acyl-CoA: cholesterol acyltransferase (ACAT) activity in chicken hepatic tissues was developed using silicic acid chromatography. Its prognosis is usually poor without surgical intervention and long-term survival into adulthood is rare. To date, the ADP receptor antagonist, clopidogrel, appears to provide the best antithrombotic result with the fewest side effects.

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Luciferase reporter/promoter studies revealed multiple elements being required for the activation and for the spatial control of transcription. Rats receiving gentamicin demonstrated progressive renal proximal tubular necrosis at the end of 7 days administration.

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To the extent society views these transfers as meritorious, our findings suggest caution regarding initiatives to limit or eliminate the tax subsidy. The potency and efficacy of clonidine to inhibit peristalsis were markedly decreased after endotoxin administration, while the potency of the other test drugs was less attenuated. The presence of S-layer proteins in Lactobacillus brevis was examined by SDS-PAGE analysis.

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In addition, our data suggest that Vpr governs HIV-1 nuclear import through a distinct pathway. We then measured the expression of mRNA encoding dentin sialophosphoprotein (DSPP) as a marker of odontoblasts in rhBMP-2-stimulated human pulp cells using a quantitative polymerase chain reaction. Effect of vertebrate hormones on the cyclic AMP level in Tetrahymena. Very few giant serotonin neuron output synapses were found in either lobe. Failure of trabeculectomy is attributed to an exaggerated wound healing response at the episcleral level.

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Animal experiments and epidemiologic data have suggested that the use of nonsteroidal antiinflammatory drugs (NSAIDs) may decrease the incidence of large bowel carcinoma. The antiphospholipid (aPL) antibody syndrome is characterized by severe pregnancy complications, the cause of which remains unknown. A directed Medline literature review of nanotechnology was performed. An inhibitor of p38, SB 202190 or a DNM of p38alpha kinase (DNM-p38alpha) suppressed UVA-induced phosphorylation of eIF2alpha (Ser(51)) but had no effect on phosphorylation of PKR (Thr(451)). In contrast, SigB, although showing some overlap in function with SigA, is more like the alternative sigma factor, sigmaS, which controls the transcription of the gearbox type of promoters.

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In order to elucidate the genetic basis of autosomal dominant retinitis pigmentosa (adRP) in a large eight-generation family (UCLA-RP09) of British descent, we assessed linkage between the UCLA-RP09 adRP gene and numerous genetic loci, including eight adRP candidate genes, five anonymous adRP-linked DNA loci, and 20 phenotypic markers. Interpretation of the SF-12 summary scores in our study would have overlooked seemingly important differences in health that were picked up by the RAND-12 summary scores. We used a random-effects model and explored for sources of heterogeneity. Effect of smoking cessation on the respiratory health of general population

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Additionally, there is a body of literature which reports that leukemia cells produce GMCSF, IL6, and other cytokines. The relatively rare occurrence of these tumors and the varied extent of disease have made it difficult for surgeons to establish definitive surgical indications or predict favorable neurological outcomes based on preoperative imaging data. Oxidative stress is a major cause of cardiovascular tissue fibrosis. Although therapeutic developments have improved the prognosis for those with cardiovascular disease, mortality rates have nevertheless remained virtually unchanged in the last twenty years.

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Psychotherapy and survival in cancer: the conflict between hope and evidence. Neither orthostasis nor blood loss caused significant changes in the umbilical systolic/diastolic ratio.

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Fortunately, with increased monitoring of the blood supply, they have been reduced. The aim of this study was to assess the direct medical costs of patients suffering from ADHD and their quality of life as well as the direct medical costs of their mothers. We now demonstrate that monoubiquitination on a single lysine residue is sufficient to signal receptor internalization, a modification distinct from that required for proteasome recognition. Effect of mass medication with antibiotics at feedlot entry on the health and growth rate of cattle destined for the Australian domestic market.

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The formulation of cationic polymers of polyethylenimine (PEI) with plasmid DNA has been optimized to deliver genes into the Xenopus tadpole brain in vivo. The checkpoint kinase 1 (Chk1) preserves genome integrity when replication is performed on damaged templates.

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We have raised some arguments for the existence of trans-active regulators, acting as repressors of Amy1-2 in adults. Our results demonstrate that pH and concentration of intravesical oxybutynin solution may play an important role in relaxation of the bladder.

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More data on larger patient groups are needed and will certainly shed new light on the importance of impaired fibrinolytic function in the etiology of CHD in the near future. THE MICROSCOPIC EXAMINATION OF LARGE NUMBERS OF SERIAL SECTIONS USING A SLIDE FRAME The paper uses a cross-sectional design with (1) a standard regression framework to estimate the impact of prescription coverage on utilization controlling for potential selection bias with covariate control based on the Diagnostic Cost Group/Hierarchical Condition Category (DCG/HCC) risk adjuster, and (2) a multistage residual inclusion method using instrumental variables to control for selection bias and identify the insurance coverage effect. These results were documented by electron microscopic observations which revealed the different steps in the invasion pathway, including a fusion event between phagosomes containing S. Its complex with the 40S ribosomal subunit (48S preinitiation complex) was then isolated by sucrose gradient sedimentation from ascites carcinoma Krebs2 cell extracts after preincubation with the transcript.

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During a 1-year period, the data of age, body mass index, antipsychotic drugs and fasting blood samples for serum lipid profiles were collected at baseline and endpoint of 3 weeks. The effect of LIGHT in inducing maturation of monocyte-derived dendritic cells from MDS patients. On the basis of previously reported experiments in heterologous expression systems, we suggest that the modulation of channel open time is related to the expression of the AChR incorporating the gammas subunit.

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Three WHO regions--the Region of the Americas (1994), Western Pacific Region (2000), and European Region (2002)--have already been certified free of indigenous wild poliovirus. However, many of the current vaccines are deficient in efficiency, potency, or safety.

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Upregulation of endothelial nitric oxide synthase (eNOS) activity is pursued as a strategy for the prevention of cardiovascular diseases. In both experimental groups, the multi-unit auditory receptive fields were broad and all spatial tuning parameter values were significantly greater than the equivalent values from a control group of normal animals.

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It was shown that structure and chemical properties of out-of-equilbrium states can differ considerably from the equilibrium ones. The diagnosis of pneumocystis pneumonia (PCP) is difficult because it requires microscopic examination to identify pneumocystis from induced sputum or BAL fluid. Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins.

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Novel broad-range reverse transcription-PCR/nested assays targeting the region coding for the RNA-dependent RNA polymerase were developed, amplifying fragments of 516 bp and 687 bp in the nested reactions for genogroups II and I, respectively. Symptomatic patients with achalasia were randomised to botulinum toxin (22 patients, median age 57 years) or pneumatic dilatation (20 patients, median age 56 years). Radiation therapy plays an important role in the management of primary and metastatic tumors of the CNS. Four clones were established, out of which clone M1 had the highest amounts of PGI2 production, as well as plasminogen activator activity and internalized acetylated low density lipoprotein. Esomeprazole is approved for the treatment of symptomatic gastroesophageal reflux disease, the healing of erosive esophagitis, and maintenance of healing.

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Visualization analysis and half-quantitative analysis were used to determine the signal characteristics. Preoperative use of recombinant human erythropoietin in pediatric orthopedics: a decision model for long-term outcomes. Although there is no clear evidence of harmfulness, there is general agreement that occupational exposure should be minimized for precautionary reasons. Diagnosis of mycobacterial disease by biochemical and immunological parameters

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From the Connecticut Tumor Registry, we obtained data on 25,091 patients with localized (node-negative) and regionally metastatic (node-positive) breast cancer who were diagnosed over the two decades between 1965 and 1984, with follow-up through 1993. Last decades numerous experimental studies show that UV rays damage DNA, cause gene mutations leading to the development of malignant tumors such basal cell carcinomas, squamous cell carcinomas and melanomas.

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Within-group comparison of pretreatment and posttreatment outcome measures demonstrated that while the NST group did not change significantly with regard to symptomatology, the CBT-SAP group had highly significant symptomatic improvement on most outcome measures. The prevalence of the metabolic syndrome (MetS), CVD and type 2 diabetes (T2D) is known to be higher in populations from the Indian subcontinent compared with the general UK population.

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Mass balance calculations showed that limit concentrations are not exceeded either for worst case loading and considering 15 years of operation. This paper reports the evaluation of an expert system whose output is a three-dimensional geometric solid.

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Implementation of real-time two-dimensional nuclear magnetic resonance spectroscopy for on-flow high-performance liquid chromatography. Special projections are reported for tomography of the temporal bone, with special emphasis on the indications for such procedures.

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DL-tetrahydropalmatine-produced hypotension and bradycardia in rats through the inhibition of central nervous dopaminergic mechanisms. To develop a prediction rule for the use of chest radiographs in evaluating for community-acquired pneumonia (CAP) based on presenting signs and symptoms.

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In vivo and ex vivo magnetic resonance spectroscopy as applied to pharmacokinetic studies with anticancer agents: a review. Increased complexity of wild-type adeno-associated virus-chromosomal junctions as determined by analysis of unselected cellular genomes. Every line is scanned 128 times by a line sampling rate of 4000 Hz. Two different invasive versus noninvasive strategies in the management of non-ST elevation acute coronary syndromes. This article will review current developments in drug discovery alongside contemporary evidence for potential substrates and mechanisms of antipsychotic action.

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Gln192Arg polymorphism of the PON1 gene is not associated with sporadic AD in Chinese. During SWS substantial part of neurons displayed changes in activity which were phased-locked with sleep spindles. The ways of sleep activity propagation in the neuronally isolated cortex are discussed. To define the frequency and characteristics of human immunodeficiency virus (HIV)-associated rheumatic manifestations in patients receiving highly active antiretroviral therapy (HAART) referred to a rheumatology clinic. Fusion of Sendai virus with the target cell membrane is required for T cell cytotoxicity.

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Data are from the National Heart, Lung, and Blood Institute Twin Study-a longitudinal cardiovascular epidemiologic study of World War II male veteran twins currently in its 27th year of follow-up. The segregation of cells into germ layers is one of the earliest events in the establishment of cell fate in the embryo. At this time histopathology revealed an early invasive lentigo maligna melanoma.

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Determination of the psychosocial status and assessment of the level of satisfaction in Malaysian cleft palate patients and their parents. Although only five of these patients made a further attempt during the period of clarithromycin 250 mg for tonsillitis antibiotics review, the method of selection of patients does not allow definite conclusions to be made. Rapid evaluation of soluble HLA-G levels in supernatants of in vitro fertilized embryos. The cefoperazone pharmacokinetics was studied in the patients with normal renal functions after surgical operations on the organs of the chest and abdominal cavity. These results have shown that nonspecific immunosuppression by cyclophosphamide treatment strongly affects the expression of AMV in age-resistant chickens.

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Detection of sodium channel activators by a rapid fluorimetric microplate assay. Small amounts of virus-specific enzyme could be detected using this combination of electrophoresis and antibodies and replacing ATP by CTP in the substrate medium. Furthermore, this cytokine induces expression of Lyb-5 alloantigen on B cells from immunodeficient mice. Synthesis of the inner ethambutol hcl cas no mitochondrial membrane and the intercalation of respiratory enzymes during the cell cycle of Chlorella.

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Their discovery opened the door for new chemistry solox denatured alcohol of synthetic fungicides. Neuromodulatory inputs maintain expression of a lobster motor pattern-generating network in a modulation-dependent state: evidence from long-term decentralization in vitro. Further on, in a short literature survey, we depict the meaning of collective drug experiences with plants containing atropine-like substances in ancient and modern times. Metallic-net filters were more effective than glass filters in suppressing EM radiation. The cases are found mainly in areas undergoing development outside the old centre of the city, and may be associated with poor waste disposal and heaps of construction waste.

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In this paper the concept and technical developments of fiber FISH are reviewed with the emphasis of comparison on the various protocols. Using data from a prospectively collected population-based database of admissions to neonatal intensive care units in New South Wales and the Australian Capital Territory, we identified all low-birthweight infants undergoing cardiac surgery between 1992 and 2001. From the Asian perspective, we are more susceptible to having a higher chance of both false negative and false positive FDG-PET erazon gel polish cases. Therefore, these neurons are well positioned to mediate leptin effect on reproductive control.

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Acquired segmental iris dilator muscle synkinesis due to deglutition. Awareness of the condition and high index of suspicion vicodin and ibuprofen interaction are keys to early diagnosis and prompt intervention. Intermediate filament protein domain interactions as revealed by two-hybrid screens. CD11b, CD18, and CD32 monoclonal antibodies inhibited degranulation, demonstrating dependence on complement receptor type 3 (CR3), and the low-affinity Fc receptor for IgG.

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Treatment of esophageal varices by endoscopic ligation in children. MyoD interacts directly with both p300/CBP and PCAF, forming a multimeric protein complex on the promoter elements. The solid-phase sequencing method was compared to double-strand sequencing of preparative gel electrophoresis-purified amplification products and found to give more consistent results. Ten preterm infants at term-equivalent age had supratentorial lesions (intraventricular indomethacin pain relief hemorrhage, periventricular leukomalacia, or hemorrhagic parenchymal infarction), and the median thalamic and lentiform volumes for this group were 10.4 and 1.7 cm3, respectively.

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The outcome of interest was a head injury requiring medical attention within the following year ascertained by parental recall or physician claims data. Multiplex ligation-dependent probe amplification (MLPA) genotyping assay for mouse models of down syndrome. Exercise response, metabolism at rest and digestibility in athletic horses fed high-fat oats. Roles of prostaglandins (PG) gabatin vs court of appeals 158 scra 700 F2 alpha, E1, E2, adenosine, oestradiol-17 beta, histone-H2A and progesterone of conceptus, uterine or ovarian origin during early and mid pregnancy in the ewe.

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Cell proliferation in mo lap vs rolap mo weakly metastatic KM12, but not in strongly metastatic KM12SM, was inhibited by heparin on plastic. Although there has been some interest in their use for treatment of dysmenorrhea, the principal clinical venue for such agents has been thought to lie in treatment of preterm labor.