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Activation of Nrf2 by Cr(VI) was accompanied by the nuclear translocation and deubiquitination of Keap1 implicating recycling of Keap1 in Nrf2 signaling. The authors have demonstrated previously that the combination of epirubicin and paclitaxel is very active against metastatic breast carcinoma and tolerated by patients.

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Motor coordination in children with congenital strabismus: effects of late surgery. This study compared the use and efficacy of ciprofloxacin to cefuroxime axetil for adult patients with acute bacterial sinusitis. Effect of IL-10 on the mite antigen-induced IFN-gamma production by peripheral blood lymphocytes from individuals with bronchial asthma

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A DAS server allows exporting the results to the Ensembl viewer where contextual genomic information can be obtained. Regional cerebral blood flow was studied in a patient with Munchausen syndrome using high resolution Tc-99m HMPAO SPECT. EXISTENCE OF A JUXTA-GANGLIONIC ORGAN IN APLYSIA PUNCTATA CUV (OPISTHOBRANCHIATE GASTROPOD) During infection of the gastrointestinal tract, salmonellae induce cytokine production and inflammatory responses which are believed to mediate tissue damage in the host. Subgroups were compared using measurement values on ICU admission.

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Three random translational beta-glucuronidase (gus) gene fusions were previously obtained in Arabidopsis thaliana, using Agrobacterium-mediated transfer of a gus coding sequence without promoter and ATG initiation site. The plasma 17-OHCS concentration was found to be elevated at all sampling hours in breast cancer patients, irrespective of the stage of the disease.

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Height, weight, blood pressure, heart rate, plasma glucose, lipid profiles, serum insulin and leptin levels were measured in the morning after an overnight fast Age as a prognostic factor for late local recurrence of early tongue cancer treated with brachytherapy. Many of the unstable clones were showed similar levels of instability over time. In each of 11 experiments, four calves were exposed first to an aerosol of bovine herpesvirus 1 (BHV1, virus of infectious bovine rhinotracheitis) and second to an aerosol of Pasteurella haemolytica. Similarly BALF-PICP, but not S-PICP, was significantly higher in sarcoidosis.

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The high-resolution field emission scanning electron microscope (FE-SEM) image confirms this observation. Expression of these genes could be restored to wild-type levels by exogenous supply of the photoactivatable nitric oxide donor potassium nitrosylpentachlorouthenate, but this was dependent on the timing of its activation and recovery in gene expression was only evident during the latter stages of osteoblast differentiation associated with its mineralizing activity. Decreased osteoclast formation, inhibition of osteoclast actions, and reduced osteoclast survival represent mechanisms by which antiresorptive agents could act.

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Alternatively, these miHA could be exploited as targets for a more potent graft-versus-malignancy effect. Colocalization of a partially dominant gene for yellow seed colour with a major QTL influencing acid detergent fibre (ADF) content in different crosses of oilseed rape (Brassica napus). The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma. The dialysis fluid, which contains electrolytes and the metabolic waste products, was analyzed for radiocaesium.

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The history of human sleeping sickness in East Africa is characterized by the appearance of disease epidemics interspersed by long periods of endemicity. Examination of peripheral nerve biopsy material in such cases shows evidence of both axonal and Schwann cell abnormalities with evidence of neurogenic atrophy of skeletal muscles. Results often vary in dependence on the examined parameters, on the type of the used or measured estrogens, on the measuring methods and between the different species. Binding of botulinum neurotoxin to the synaptosome fraction of rat brain. To examine the preinjury rates of Axis I disorders and the prospective rates within the first 6 years after traumatic brain injury (TBI).

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Delayed malignancy and altered growth properties of somatic cell hybrids between rat hepatoma and mouse L-cells. Dorsal and ventral NME was measured in seconds until exhaustion in a laying-down position.

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aeruginosa could be detected, which supports the idea of a combination therapy. A study conducted at an urban community hospital found that medication errors are under-reported and that nurses view medication errors as multiple cause incidents.

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The range of virus strains detected and the sensitivity of detection were evaluated by using a representative panel of 21 well-characterized SRSV strains. Importance of timing in the evaluation of hematuria and proteinuria after living-donor kidney transplantation.

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A rapid, sensitive and specific assay is needed to detect positive samples in routine analysis, and immunoassay offers practical advantages over the conventional instrumental methods in rapid analysis of zeranol residues. 81, provides a convincing argument about the need for mental health specialty services for children, adolescents, and their families (Thomas.loc.gov, 2003). The goal of this study is to design a pressure-flow nomogram (PdetQmax/Qmax) and define cut-off values for obstruction. A prevalence study of recurrent shoulder dislocations in young adults. We have used gene competition to distinguish between possible mechanisms of transcriptional activation of the genes of the human beta-globin locus.

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Extension from an immunoreactive complementary DNA clone yielded the entire genome (9392 nucleotides) encoding a polyprotein of 2873 amino acids. This is the first record of a species of Allassogonoporus in South America and the first record of a digenean parasitising D. As judged by circular dichroism, ultracentrifugation and native gel electrophoresis, anti-APCp1 formed a specific, helical, dimeric complex with the target APC coiled coil. Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67. In each case, the results of 3-D TTE were compared with 2-D images to disclose additional qualitative information provided by 3-D examination.

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Training of hypertensive patients is a widely disputable problem. The -250G/A polymorphism in the hepatic lipase gene promoter influences the postprandial lipemic response in healthy men. Antibiotic resistance: epidemiological developments and preventive measures While Alz 50 can be a useful reagent in these studies, there are limitations to the utility of this antibody, and it is important to recognize that appropriate controls must be performed to establish the specificity of observed immunoreactivity. Fifty-eight patients recruited from three rural primary care clinics completed the 36-item Short Form Health Survey (SF-36) and the Typology of Psychic Distress (PsyDis).

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In later stages of development, activity was also detected in ground tissue and parenchyma cells associated with vascular tissues. Associations between body composition, anthropometry, and mortality in women aged 65 years and older. Pretreatment with IRN 24 h before 5-FU increased the number of tumor cells in S-phase and the antitumor activity in a preclinical system. The ER-alpha gene was scanned in a Taiwanese clinical breast cancer group (189 patients) and in healthy individuals (177 healthy control individuals). However, the accumulation of both E2B and E4 mRNAs at all times was severely reduced.

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The comparison of Doppler ultrasonographic measurements of the challenge group before and after the gluten challenge revealed that the peak systolic velocity, resistive index, and blood flow of the superior mesenteric artery were changed significantly. To determine whether specific activation of the MEK/MAPK pathway was sufficient to induce hematopoietic differentiation, U937 cell lines were established that conditionally expressed the activated MEK1 mutant under the control of the human IIa metallothionein promoter. Developmental changes in the pattern of expression of 11 GABA(A) receptor subunits in individual rat embryonic hippocampal neurons on days 1-21 in culture and acutely dissociated hippocampal neurons from postnatal day (PND) 5 rat pups were investigated using the technique of single-cell mRNA amplification. Glutathione S-transferases (GSTs) are a multifunctional group of enzymes, widely distributed in aerobic organisms, that have a critical role in the cellular detoxification process. We included all randomized controlled trials (RCTs) in which one or more antibiotics were tested for the treatment of CAP in ambulatory adolescent or adult patients.

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The objective of this study was to investigate the use of sustained delivery of insulin-like growth factor-1 (IGF-1) for treatment of degenerative discs using the adult male rat as a model. Involvement of the inferior vena cava has traditionally been considered a contraindication to resection for advanced tumors of the liver because the surgical risks are high and the long-term prognosis is poor. Our findings suggest that a diet rich in fiber may have a moderate BP-lowering effect and indicate the need for further investigation of this important question.

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Four aspects of S are briefly discussed in this report: (1) the final biochemical step permitting initiation of DNA synthesis, (2) determination of replication timing of individual genes and its mechanism, (3) S phase processes that lead to the onset of M phase, and (4) resetting the S-phase machinery. The amount of brain-type creatine kinase increased only twofold during P19 differentiation. A variety of devices, often using contralateral shoulder motion, sends signals via a small external controller and transmitting coil to an implanted stimulator.

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Costs of a medical education: comparison with graduate education in law and business. At 2-10 mM NaC concentrations, only primary aggregates were detected. Detailed questionnaires were prospectively collected for all infants with probable neonatal seizures for a period of 5 years.

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The prevalences of PBC and AIH are of the same order of magnitude and about twice as high as that of PSC. The most potent inhibition of phosphorylation was demonstrated by homologous peptides derived from the regions located on cathepsin molecules opposite the oligosaccharide chains which are phosphorylated by the phosphotransferase. Methods are described for the rapid detection of beta-D-glucosidase and phosphatase in mycoplasma cultures using fluorogenic 4-methylumbelliferone substrates. Nine patients underwent full thickness chest wall resection and reconstruction in our department between January 1981 and December 1994.

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Its safety profile is excellent because of the continuous normalcy of plasma T levels. Polymerase chain reaction (PCR)-based assays were developed to detect virulent Rhodococcus equi in transtracheal aspirate samples from sick foals showing respiratory signs. Screening for familial hyper-beta-lipoproteinaemia in children in hospital. The treatment of diabetic foot ulcers: reviewing the literature and a surgical algorithm. For women, those with RRMS had significantly greater belief in their ability to control their MS and function with it than women with progressive forms of MS.

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Patients undergoing scleral buckling and cryotherapy suffer from mild to moderate postoperative pain. In vitro and in vivo immunosuppressive activity of a novel anthracycline, 13-deoxy, 5-iminodoxorubicin. This species was precipitable by monoclonal antibodies specific for relaxin and had a retention time on reverse phase HPLC comparable to that of relaxin. The genomic rate and distribution of effects of deleterious mutations are important parameters in evolutionary theory.

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The effects of A-438079 on evoked firing were diminished or absent in sham rats. Nonorganic hearing loss and child abuse: beyond the sound booth. Interestingly relatively high expression of CENP-B gene was also found in M phase, showing the continuity of the CENP-B gene expression during the cell cycle. The location of activating mutations both within a single receptor and across receptors is widespread, with changes reported in the seven-transmembrane domains, the second and third intracellular loop. Ideal proportion is directly related to divine proportion, and that proportion is 1 to 1.618.

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Nine other patients had been followed with no evidence of local relapse for 23.7 to 54.6 months. Between 2001 and 2004 the social distance toward persons with schizophrenia decreased in the general population. Each phenotype was subject to its own environmental influences that were not shared. In addition, the 71E region contains another gene (I71-1) with the regulatory and biochemical characteristics of the salivary gland intermolt glue proteins. We briefly review the various findings associated with cardiac myxomas (nonfamilial and familial) with emphasis on cutaneous presentations.

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Addressing the needs of basic and clinical research: analysis of graduates of the University of Pennsylvania MD-PhD program. In particular, effects on maturity onset diabetes and hyperuricaemia, as well as a very interesting fibrinolytic potential, have been described for some of them.

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Population models show that these levels of predation are sufficient to cause population decreases. The mtmR gene restored actinorhodin production in Streptomyces coelicolor JF1 mutant, in which the actinorhodin-specific activator ActII-orf4 is inactive, and also stimulated actinorhodin production by Streptomyces lividans TK21. Prevalence and risk factors of diabetic retinopathy among noninsulin-dependent diabetic subjects. Pestiviruses are the only members of the Flaviviridae that encode a nonstructural protease at the N terminus of their polyproteins.

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Hamster embryo cells transformed by herpes simplex virus: reactions with adeno-associated satellite virus (AAV) and its adenovirus helpers. An efficient and safe herpes simplex virus type 1 amplicon vector for transcriptionally targeted therapy of human hepatocellular carcinomas. The role of UDCA in chronic hepatitis and alcohol induced liver disease needs to be clarified in further studies. A novel approach to induce both cellular and humoral immunity is genetic vaccination, the injection of antigen-encoding naked plasmid DNA.

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Relation between slow-wave frequency and spiking activity during the migrating myoelectric complex in dogs. There was no change in the number of Con A-receptors on 3T3 cells after EGF treatment. Southern blot analysis suggested that Mi-vp-2 is probably a member of a small multigene family. Perceptions of contraception, non-protection and induced abortion among a sample of urban Swedish teenage girls: focus group discussions. Tumor-infiltrating lymphocytes from ascites fluid contain cells capable of major histocompatibility complex-restricted and major histocompatibility complex-nonrestricted cytotoxicity.

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Lipoxygenase activity and lipid peroxidation were also increased during low temperatures, suggesting that lipoxygenase-mediated peroxidation of membrane lipids contributes to the oxidative damage occurring in chill-stressed leaves. Oxazolopyrimidine and thiazolopyrimidine derivatives related to the xanthines. Chemical potentials in dense charged classical or quantal systems.

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Excited-state atomic-beam studies of submonolayer adsorption on a fine mesh. Deoxyribose phosphate excision by the N-terminal domain of the polymerase beta: the mechanism revisited. It is concluded, therefore, that hepatitis A-associated virus particles are more likely to be classified with the picornaviruses than with the parvoviruses. Here, we searched for conformational effects of monomer binding to the latter functionally important region.

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The transposon disruptions were mapped to 95 different genes, virtually all of which are also present in the genomes of other F. The terminal products of this process are commonly cells with a complete deletion of the amplified allele of marker genes and are therefore haploid for these loci on the homologous chromosome.

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All the assays revealed a galactose-specific lectinic activity was present that in the flocculent as well as in the non-flocculent strain. A radiation-sensitive host function required for initiation of herpesviral protein synthesis.

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Specific antibodies against alpha-tubulin, acetylated alpha-tubulin, tyrosinated alpha-tubulin and polyglutamylated alpha- and beta-tubulin were used to compare the distribution of posttranslationally modified tubulin in the vestibular end-organs of the gerbil. Here, we report the thermodynamic characterization of the stability, analyzed by differential scanning calorimetry, of three DNA quadruplexes of different molecularity, all containing four G-tetrads. An iterative process of cognitive testing, item revision, and item reduction was followed to identify the most appropriate items and optimal response scales. Healing connections: on moving from suffering to a sense of well-being.

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Federal Section 1915(b) and Section 1115 waivers, through the Health Care Financing Administration, are the primary modes for implementing Medicaid-managed mental health and chemical dependency services. Amino acid residues with aromatic side chains, such as Tyr and Phe, are known to play essential roles in forming and stabilizing the amyloid fibrils of pathogenic polypeptides by affecting their amyloid forming propensity. The effect of suctioning type on VAP and mortality was reported as risk difference (RD) and duration of mechanical ventilation (MV) as mean weighted difference (MWD).

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The density profile was analyzed, and the structure of the films showed an interior region of the bulk density. Endocrine disrupter nonylphenol and bisphenol A contamination in Okinawa and Ishigaki Islands, Japan--within coral reefs and adjacent river mouths.

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GITR activation, upon interaction with its ligand (GITRL), functions as a co-activating signal. We describe a statistical method for estimating the effectiveness of a stock enhancement programme using nuclear DNA loci.