Acupain is a strong painkiller. It's used to treat moderate to severe pain, for example after an operation or a serious injury.

It's also used to treat long-standing pain when weaker painkillers no longer work.

Acupain is available only on prescription. It comes as tablets, capsules and liquid drops that you swallow. It can also be given by injection but this is usually only done in hospital.

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To elucidate the risk factors that can affect the rate of cholangitis after hepatolithiasis treatment. The treatment regimen consists of a total dose of 36.25 Gy delivered at 7.25 Gy per fraction over 10 days. The identification of new prognostic factors is necessary to improve survival. Mutants in the Salmonella Pathogenicity Island 1 (hilA and sipA) and 2 (ssrA) were tested for their potential to induce protection against infection by homologous virulent Salmonella Enteritidis challenge strain, administered 24h later, in chickens.

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Diabetes mellitus (DM) is often combined with arterial hypertension, which increases the risk of serious complications. Behavioural endocrinology and reproduction: an evolutionary perspective. Human papillomaviruses and their possible role in squamous cell carcinomas.

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A three-round Delphi study was conducted, involving 38 selected experts who suggested and assessed potential sources by applying agreed criteria. ON THE WORK OF THE KHARKIV BRANCH OF THE SCIENTIFIC PHARMACEUTICAL SOCIETY The danger of possible superinfection should always be taken into consideration.

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Single-chain antibodies with short CBHI linkers of 11, six and two residues had a tendency to form multimers which led to a higher apparent affinity. Changes in rSO2 were detected before any adverse clinical event was observed.

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The activity on two series of microorganisms, Pseudomonas aeruginosa and Staphylococcus aureus, was examined. Substantial sample sizes are required for performance assessment and model comparison in external validation. Oncologist-patient discussion of adjuvant hormonal therapy in breast cancer: results of a linguistic study focusing on adherence and persistence to therapy. Complete genital prosthetization in patients treated with bilateral orchiectomy for metachronous testicular cancer.

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The results showed that children with GID had more negative emotions and a tonically elevated SCL. This study showed no clinical benefit for repetition of extrastimuli that have failed to induce a ventricular tachyarrhythmia during programmed ventricular stimulation. However, to obtain such accuracy an exchange-correlation functional capable of describing the diffuse Rydberg states must be chosen. Despite a close structural similarity, compounds 2a and 2b induced apoptosis in Jurkat leukemia cells in mechanistically different ways.

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Rats showed a significant weight gain and had no evidence of postoperative leakage. Multiple-locus VNTR analysis revealed extensive diversity within the global isolate set containing B.

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In vitro stimulation of renal tubular p-aminohippurate transport by dexamethasone in kidney tissue of immature and adult rats. We searched the Cochrane Library (Issue 2, 2003), MEDLINE (1966 to May 1996), EMBASE (1980 to 1996), Biological Abstracts (1985 to 2003), the Oxford Pain Relief Database (1950 to 1994), PubMed (1996 to 2003) and reference lists of articles. At the end of surgery, neostigmine 0.04 mg/kg IV was given to reverse the residual block. Since atrial fibrillation is a strong independent risk factor for prolonged intensive care unit stay the preservation of sinus rhythm must be aimed at.

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Scutellarin protects PC12 cells from oxidative stress-induced apoptosis. Phosphorylation of CagA occurs within the C terminus of the protein and is mediated by members of the Src family of tyrosine kinases. Animals were anesthetized and underwent a 1-cm midline lower abdominal incision.

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Six years ago several people had their doubts as to whether a Global International Waters Assessment would be worth the money and effort. A mild case of Friedreich ataxia: lymphocyte and sural nerve analysis for GAA repeat length reveals somatic mosaicism.

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Moreover, natural human mTERF is also a phosphoprotein and its termination activity is inhibited by dephosphorylation. Treatment with an anti-IL-4 monoclonal antibody blocks suppression of collagen-induced arthritis in mice by oral administration of type II collagen. Both sections of the control region were sequenced directly while the ND-5/6 fragment was sequenced in from each end only. Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man. This route is a common mechanism for the evolution of complexes and clusters of protein interactions.

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On the account of particulars from literature they refer to the possibility of using various autolognal venous grafts and also artificial vascular protheses. Direct laryngoscopy with the aid of a fiberoptic bronchoscope for tracheal intubation. The remarkable evolutionary conservation of the vertebrate eye provides the basis for using the zebrafish as a model system for the detection and analysis of genetic defects potentially related to human eye disorders.

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Bactericidal activity of streptomycin and isoniazid in combination with p-aminosalicylic acid against Mycobacterium tuberculosis. This temporal resolution enables the disc sensilla to represent behaviourally relevant changes in heat stimuli in a thermally patchy environment. New compounds can be discovered by screening, modification of existing compounds, rational drug design, and serendipitous basic research observations. In the present studies we have shown that two H7-resistant protein kinase C activities may be isolated from (pituitary) gonadotroph-derived alpha T3-1 cells using hydroxyapatite chromatography. Randomised controlled trials involving adults aged 16 years and over presenting with dental and/or facial injury relating to domestic violence in any healthcare setting.

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The aim of this review is to summarize the meaning and accuracy of current methods and their usefulness in diagnosis and study of thyroid diseases of pediatric patients. Furthermore, in some species H4 gene variants were detected, which result in amino acid differences.

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Utilization of these solvents alone did not produce red and paprika oleoresins that meet commercial specifications. In this study we investigated whether this cell type is present in early stages of prostate development, using keratin antibodies specific for them. Four typed bacterial strains, S aureus ATCC 12600, Bacillus subtilis ATCC 6051, Pseudomonas aeruginosa ATCC 10145 and Escherichia coli ATCC 117755 were included as reference organisms.

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As absorption was specific to the ileum, it was inferred that the conjugated hormone was taken up by the bile salt transporters. The high degree of sleep disruption in this sample may relate to living in a different culture. The microtubular protein, beta-tubulin, appeared to have an altered mobility while the major intermediate filament protein, glial fibrillary acidic protein (GFAP), was decreased.

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They may contribute to the endothelial dysfunction underlying the maternal syndrome of pre-eclampsia. Cyclic AMP formation by the isolated granulosa cells of the follicles in various stages of development was studied in response to the administration in vitro of gonadotrophins. A wide bridge whose width does not vary much with tip-surface distance can increase its volume as distance is increased. Release of lactate dehydrogenase and cellular adenosine triphosphate were measured. In this process, fragments of cleaved polysaccharide are preferentially transferred to other xyloglucan molecules or their oligosaccharide subunits, with overall retention of the anomeric configuration of the glycosidic bond.

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In genetic studies of C57BL/10 and BALB/c mice, inducibility of xenotropic murine leukemia virus from tissue cultures by treatment with 5-iododeoxyuridine shows single gene segregation ratios. Surface-attached ligands were revealed by the indirect immunofluorescent methods.

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In the six pregnancies at risk for galactosemia, four were considered to be unaffected and two to be affected. This demonstrates that it is possible for a peptidyl-tRNA species, in the midst of translation, to be processed by the endoplasmic reticulum signal peptidase implying that the peptidase is closely associated with the mammalian translocon.

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Although INH concentrations in the urine were high at the onset of the instillation, in vitro experiments indicated that the effect of INH may not be caused by killing of the BCG organisms shortly after application in the bladder. Thrombosis remains one of the leading causes of mortality and morbidity in developed countries. Our results indicate that utilizing retrovirally transduced B cells as vehicle may be a feasible approach for tolerance induction in patients with MS. Illustrating experimental results demonstrate a much improved performance of the proposed approach in comparison with existing methods currently used in 3-D mesh smoothing.

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DAK inhibition of membrane-associated AEA amidohydrolase is irreversible because hydrolytic activity is not restored with extensive washing or dialysis of the membranes. In accordance with the literature, this data point to a potential etiologic role of chlorinated hydrocarbons (particularly trichloroethylene) and malignant lymphoma. This review traces the history of poxviruses as pathogens and immunogens, examines some of the approaches that have been taken to design poxviral vaccines for HIV and cancer and summarises the results of existing clinical trials of these vectors. Impairment of cardiac function has also been associated with growth hormone deficiency (GHD). Dissipation of some organochlorine insecticides in cropped and uncropped soil.

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A transvaginal drainage of the abscess was performed and the thrombosis of the vena cava treated with Heparin and thrombectomy. We show in this paper that neither sarcomeric myosin nor actin are required for myoblast fusion or the subsequent morphogenesis of muscle fibres, i.e. We also discuss the applications of PDT for advanced lung cancer and combined therapy using PDT and other treatments for lung cancer. The times to maximum plasma concentrations of nifedipine and its metabolite produced at first pass were reduced when standing or lying on the right side.

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Possibility of EB virus preferentially transforming a subpopulation of human B lymphocytes. Catastrophic progression of the disassembly of a modular acetabular component. This is accompanied by a marked reduction of KIF3Abeta protein levels.

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A prospective multicenter study based on known tumor-cell percentage of fresh frozen carcinoma biopsies was established to determine the HPV prevalence. This study has produced the largest dataset of pre- and post-ban SHS levels in pubs of all worldwide smoke-free legislations introduced to date. Movement artifacts were eliminated by the use of a window technique. This measurement has been proposed for use as a new potential diagnostic method to assess intracavernous fibrosis. Comparative evaluation of life cycle assessment models for solid waste management.

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Objectives for this experience were defined and students evaluated the effectiveness of their preoperative teaching and monitored the patients for potential complications. A prior observation that ganaxolone appeared to reverse the marked behavioral changes induced by the convulsant pentylenetetrazol (PTZ) was systematically examined in the present study. This suggests that arteriolar smooth muscle has a higher capacity for aerobic metabolism than does arterial smooth muscle. Case 3: A 64-year-old female was diagnosed as having pyogenic discitis and osteomyelitis at the L5-S1 level. The reactions of hydrated electrons (eaq-) with amino acids were investigated by the spin-trapping method and by electron spin resonance.

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The indirect method of estimating quantal release (variance method), which assumes release is described by a Poisson distribution, seriously overestimates quantal release. Changes in sequence were restricted to specific regions of gp120, notably those equivalent to V1, V2, V4, and V5 of HIV-1, but not V3. Using a special experimental design, T2-weighted spin-echo images of cartilage-bone plugs were taken under variable angles with respect to the static magnetic field B0 to visualize the angular-dependent representation of internal matrix structures mediated by the collagen network arrangement.

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It is shown that the operating mode with the alternate transfers of the phases provides considerably higher separation efficiency than the mode with simultaneous transfers of both phases. Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130.

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Promoting health, promoting women: the construction of female and professional identities in the discourse of community health workers. The matrix metalloproteinases (MMPs) are a family of secreted and membrane-bound zinc-endopeptidases. The crystal structure at 2.0-A resolution of the complex of the Escherichia coli chemotaxis response regulator CheY and the phosphoacceptor-binding domain (P2) of the kinase CheA is presented. We measured the degree of retropulsion before and after vertebroplasty to evaluate changes in spinal canal dimension.

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Many cell cycle regulatory proteins have been shown to be able to regulate cell death. Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet. Predicting the effect of nonionic surfactants on dispersed droplet radii in submicron oil-in-water emulsions. Products are sensitive to treatment with RNase but not DNase and depend on the splicing activity of the intron.

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The mean Z-line and M-line widths from each of 19 muscle fibers containing the fingerprint inclusions were calculated. Three weeks daily corticosterone treatment (10 mg/day) induced a marked increase of CB-ir exclusively in the CA1 pyramidal cell layer. Horses breathing a gas of greater density than air will exhibit greater transmural pulmonary arterial pressures (TPAP) and more severe EIPH, and horses breathing a gas of lower density than air will exhibit lower TPAP and less severe EIPH, both compared with horses breathing air. Separation and quantitation of intracellular forms of poliovirus RNA by agarose gel electrophoresis. At 41 degrees, the transformation-nonpermissive temperature, alkaline phosphatase activities were similar to those of chick embryo cells.