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Novel doxorubicin-monoclonal anti-carcinoembryonic antigen antibody immunoconjugate activity in vitro. The defibrillators were discharged into resistive loads of 50, 90 and 130 Omega, simulating transthoracic impedance.

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At the age of four, he developed partial paresis of the left limbs after polio immunization. An experiment was conducted in calves to investigate the efficacy of a morantel sustained release trilaminate bolus (MSRT) to control gastrointestinal parasitism and to assess the development of immunity during the use of MSRT. In a public hospital, diagnostic delay is related to inadequate access to surgical consultation and a delay in operating room access.

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Mice from which the TF cytoplasmic domain has been deleted (TF Delta CT mice) show enhanced PAR-2-dependent angiogenesis, in synergy with platelet-derived growth factor BB (PDGF-BB). The results obtained up to 1993 have been recorded in a data base. Using a 125I-deoxyuridine (125I-UdR) release assay, cord cells were shown to also have higher apoptotic LAK activity against YAC-1 target cells.

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All the genes identified on this fragment are transcribed in the same orientation and could form a large operon. Compared with controls, the transplanted pyramidal neurons showed a significant reduction of apical primary dendrites and basal dendritic branches, i.e. These dimensions reflect developmental tasks related to academic achievement, social competence, and conduct important at both age levels in U.S. The large dispersion of 19F isotropic chemical shifts allows the simultaneous measurement of the efficiency of the different substrates, thus identifying the best substrate for screening purposes.

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Competitive repopulation studies demonstrated that overexpression of cyclin D2 accelerated myeloid reconstitution following transplantation, and, in agreement with this, cyclin D2-transduced myeloid progenitors showed an enhanced proliferative response to cytokines in vitro. As revealed by the magnitude of surface pressure increments (DeltaPi), both the quantities and the rates of penetration of the enzymes into these monolayers were lipid chemical nature and enzyme concentration dependent. Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer.

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The RA signal is mediated by two distinct classes of receptors, RA receptors (RARs) and retinoid X receptors (RXRs). These techniques are centered on a very basic understanding of the use of ionizing radiation for the treatment of cancer. Studies of pulmonary and renal immunopathology after nonlethal primary sendai viral infection in normal and cyclophosphamide-treated hamsters.

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The ability of the epidural test dose to detect subarachnoid injection remains unknown. Clinical and laboratory evaluation of patients treated with oral anticoagulation

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We present the first CT scan description and the second description of the findings on MR imaging of intramedullary sarcoidosis. Testing an ultrasonic scanner for determination of urinary bladder volume

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The development of quantitative correlations between the physicochemical properties of a compound and its ability to act as a skin sensitizer is complicated by the number of variables associated with the current sensitization test data, combined with the absence of a truly objective end point. The objective of this study was to explain the variation in cesarean section rates among hospitals (obstetrical departments) in Sweden, and to discuss its potential economic consequences. A single form of cholinesterase was detected in the parasitic nematode Parascaris equorum and purified from a low-salt Triton X-100 extract of whole animals by affinity chromatography on an edrophonium-Sepharose matrix. The ability of polymorphonuclear leukocytes (PMN) to produce H(2)O(2) in response to phagocytic stimulation was examined cytochemically using leukocytes from normal individuals and patients with chronic granulomatous disease (CGD). The lesions were pedunculated in 2 cases and sessile in the remaining 2.

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In the oldest specimens (10 months after surgery), laminated layers of graft and host approached each other and almost reconstructed the normal retinal appearance. Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation.

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Significant difference in the adherence of the tested strains to BEC was observed between HIV carriers who had been taking ascorbic acid over a 3-month period and those who had not. Effects of sequence alignment on the phylogeny of Sarcocystis deduced from 18S rDNA sequences.

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Three groups of pregnant Swiss mice were given by gavage daily doses of Al(OH)3 (166 mg/kg), aluminum lactate (627 mg/kg), or Al(OH)3 (166 mg/kg) concurrent with lactic acid (570 mg/kg) on gestational days 6-15. Residual activity of three slow-release temephos formulations against Aedes aegypti larvae. In our experience, crossed cerebellar atrophy was an uncommon manifestation of extreme prematurity complicated by severe intracranial hemorrhage and/or ischemic necrosis of white matter. Intermittent parathyroid hormone (1-34) enhances mechanical strength and density of new bone after distraction osteogenesis in rats.

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No significant differences in progesterone levels were observed between these two groups during the mid and late luteal phase. In vitro radiosensitization of human cervical carcinoma cells by combined use of 13-cis-retinoic acid and interferon-alpha2a. Results will support policy planning for the Queensland Nurses Union. Symptoms induced in tobacco ranged from a normal mosaic pattern similar to that induced by the parental U1 strain to a unique bright yellow mosaic.

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The experiments provide evidence for an antiphlogistic effect of irradiation with 5 times 1.0 Gy in vivo. Protein binding may be assayed by methods including equilibrium dialysis, ultrafiltration, ultracentrifugation, gel filtration, binding to albumin microspheres and circular dichroism.

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Within the mouth, the loss of these cells leads to mucosal atrophy, necrosis and ulceration. Katrina-related health concerns of Latino survivors and evacuees. The Y175F mutant showed properties similar to wild-type PTR1 in every aspect tested, but all the other mutants were inactive even if they were purified as tetramers. Correlation of the angioarchitectural features of cerebral arteriovenous malformations with clinical presentation of hemorrhage.

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Consistent with this mechanism, the last eight nucleotides of the 81 bases form a consensus sequence for a splice acceptor site. Prevocational medical education at the coalface: report from the 2006 national junior medical officer and director of clinical training/registrar forums.

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They are covered by the following therapeutic groups: JO1 (systemic antibiotics), JO3 (systemic chemotherapeutic drugs), JO4A (anti-tubercular), JO5A (antiviral), GO4A (antiseptic and for urinary infections) and RO5C1 (expectorants combining mucolytics and anti-infectious drugs). In this study, the agreement (i.e., on relative rankings and primary function) across sources of information regarding behavior function was examined for 19 students in a middle school setting.

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Use of coronary calcification scores to predict coronary heart disease. By that method a comparison of mATPase activity and the amount of PV within the same muscle fibre is difficult. Patients underwent transcervical tubal cannulation under fluoroscopic or ultrasound control and local injection of methotrexate (up to 50 mg). Germinal mutations in these genes predispose to appearance of the syndrome. The results of in vivo and in vitro 1H, 13C, 19F and 31P NMR spectroscopy and their correlation with the degree of resistance to anticancer drugs are discussed.

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NPC1L1 gene and protein expression were decreased by sterol influx, whereas cholesterol depletion enhanced NPC1L1 gene and protein expression. Cloning and characterization of the rat glutathione peroxidase gene. Next, animal models of vascular abnormalities will be engineered to elucidate pathogenesis, and these studies, in turn, should lead to development of novel therapies.

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Twenty-four hours after the beginning of balloon occlusion, 15 mCl of 99mTc-pyrophosphate was injected into the cranial mesenteric artery in 8 dogs and into a peripheral vein in 5. Additional evidence for this program was provided by analysis of Foxj1-null mice that failed to dock basal bodies and lacked apical actin. Time to completion, penalty score, and total score were assessed.

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Audiological evaluations were performed initially, a week after the completion of the injections, monthly in the following first 3 months, and at the end of follow-up period in RG. We believe that surgical intervention is required for selected patients. Although anaphylaxis due to trimethoprim seems to be rare, it may be more common than previously thought.

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A neuropsychological examination was used as the best reference test for the diagnosis of SCI. Patients were randomized to receive IFN-gamma (100 microg) or placebo daily by subcutaneous injection for up to 90 days. A fifth or more of a nationally representative sample of school-attending adolescents report engaging in problem behaviors such as skipping school, using alcohol, fighting, shoplifting, and stealing.

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This may explain certain aspects of impaired hippocampal functions in FAS. The influence of home- and clinic-based caring system on the economic burden of heart failure remains unknown. This is not simply due to defective cell proliferation or impaired recombinase expression. Effects of colchicoside on the common reed obtained by internal route

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We found that the glial glutamate transporters GLAST and GLT-1 were down-regulated at 60 days after initiation of chronic and recurrent seizures. Standardization and evaluation of a manual salivation method for the detection of Trypanosoma infection in the tsetse fly (Diptera: Glossinidae) Functions associated with these localizations coincide with those previously reported in yeast, suggesting a conservation of function. TCR beta chain that forms peptide-independent alloreactive TCR transfers reduced reactivity with irrelevant peptide/MHC complex. Helicases are enzymes which can unwind double-stranded regions of DNA or RNA in an ATP-dependent reaction.

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In response to nitrogen starvation, diploid cells of the budding yeast Saccharomyces cerevisiae differentiate into a filamentous, pseudohyphal growth form. The Account discusses the phenomenon of two-state reactivity (TSR) or multistate reactivity (MSR) in high-valent metal-oxo reagents, projecting its wide-ranging applicability starting from the bare species, through the reagents made by Que, Nam, and collaborators, to the Mn(V)-oxo substituted polyoxometalate, all the way to Compound I species of heme enzymes. Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein. The clinical results were evaluated using the Constant-Murley score, the UCLA score, and the DASH score.

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Loss of membrane asymmetry was determined on dexamethasone-treated rat thymocytes using the PS specific probe annexin V. These effects of phenytoin could be reversed by administering theophylline, a phosphodiesterase inhibitor, or by increasing the extracellular concentration of calcium. Neither S1 nor S2 influenced the tone of tube foot and apical muscle preparations but S2 caused relaxation of cardiac stomach preparations, antagonising the contracting action of acetylcholine. Sensitivities were higher in the allergen-specific IgGd assays, but the specificities and positive predictive values were higher in the allergen-specific IgE assays.

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An endogenous protein modulates the affinity of GABA and benzodiazepine receptors in rat brain. Supramolecular assemblies of gold nanoparticles induced by hydrogen bond interactions.

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The most dramatic changes in nucleosome structure occurred when Spt16-Pob3 and the HMG box protein Nhp6 were both present, but Nhp6 alone altered DNase I sensitivity at some specific sites, supporting an independent role for this class of proteins in the general management of chromatin properties. Each of these measures has certain advantages, although neither has been sufficiently validated to warrant large-scale use in clinical trials. The basal surface of follicle cells enlarged due to the formation of processes or ridges and invaginations.

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During the 3-year study the potted seedlings did not develop typical foliar ozone toxicity symptoms, despite the occurrence of as many as 78 h in exceedance of the National Ambient Air Quality Standard of 0.12 ppm. The alpha and beta distribution phases did not appear to be affected by hemodialysis. Although a relation between the adequacy of hemodialysis and mortality has been established, hemodialysis prescription is rarely individualized precisely in adults with end-stage renal disease in the United States. Long-term combination therapy with OHA and CSII with only basic manipulation and optimization of insulin doses exerted on basal rate or on boluses is feasible, effective and well accepted in type 2 diabetes. Systemic family therapy is an useful method of support in the rehabilitation of patients with strokes.

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BLOOD FLOW VELOCITY IN PATIENTS WITH CARDIOVASCULAR DISEASES AS MEASURED BY PNEUMOOXYHEMOGRAPHY In this article, the immediate past president of the American Organization of Nurse Executives describes how some organizations are doing just that.

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Changes in sexual functioning, attitudes and sexual behaviour in local women after mastectomy and conservative breast surgery for breast cancer were assessed in this study. We report our experience with the TCP at the University Hospital of Heidelberg, Germany, and examine the risk of anastomotic leaks with this technique. Diagnosis and management of middle ear osteomas: a case report and literature review.

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The vps mutants were isolated through their loss of ability to correctly sort the vacuolar hydrolase CPY, which travels from Golgi membranes to the vacuole through a prevacuolar compartment. The following aspects of performance are reported: within run variation determined on canine samples, between run variation using a commercial control, correlations between dry reagent and wet reagent methodology on clinical samples, and dry reagent method serum chemistry reference values for the cow, horse and dog. Declarative memory has been reported to rely on the medial temporal lobe system, whereas non-declarative memory depends on basal ganglia structures. Interactive diffusion-based smoothing and segmentation of volumetric datasets on graphics hardware.

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These data were supplemented with clinical information on infections, other diseases, drug intake, and other potentially teratogenic factors during pregnancy. We have first shown that u-PA content is a new independent prognostic marker in patients with superficial bladder cancer. Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state. Subsequently the same patients were treated with a modified FER cycle (mFER) where thawing of the frozen embryos was combined with aspiration of the dominant follicle in the natural cycle. The subiculum receives a substantial input from the caudomedial parvicellular division.

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After vaccinia was identified, investigators interviewed the woman more closely and learned that her new sex partner was a male U.S. The TEM results confirmed the functional integrity of the neutrophils, particularly those phagocytosing HA particles up to 24 h. There are 2 methods of corneal tissue procurement currently in widespread use: in situ extraction of the corneal button directly to preservation media and whole-globe enucleation of eyes with removal of the button to preservation media at a later time.

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In progressive case it is dangerous to remove the tumor for a risk of excessive bleeding and hard adhesion to the chest wall. Elucidating biological networks between proteins appears nowadays as one of the most important challenges in systems biology. Furthermore, the observed breakpoints were associated with genomic regions prone to instability due to the presence of segmental duplications. Improvement in peripheral nerve function immediately after haemodialysis. In the last few years, there have been several reports of PHF cases occurring even in vaccinated horses.