Cartan is a medicine widely used to treat high blood pressure and heart failure, and to protect your kidneys if you have both kidney disease and diabetes.

Cartan helps to prevent future strokes, heart attacks and kidney problems.

It also improves your survival if you're taking it for heart failure or after a heart attack.

This medicine is only available on prescription. It comes as tablets.

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Age-dependent expression of the cystatin-related epididymal spermatogenic (Cres) gene in mouse testis and epididymis. This review attempts to summarize the current array of biological parameters described in the literature as indices of biocompatibility and provide a critique of their utility.

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A model for cultural competence can provide a framework for psychiatric nurses and other mental health professionals (MHPs) to become more aware of Asian-American values and beliefs and provide more culturally sensitive care. Here, we used bioluminescence imaging to monitor Per2 gene expression in tissues and cells from clock mutant mice. Irradiation of cryogenic temperature sensors by gamma dose of 1 MGy. After cDNA synthesis, polymerase chain reaction was initiated using specific primers for alternate forms of the following receptors: hepatocyte growth factor (HGFR), keratinocyte growth factor (KGFR), and transforming growth factor beta receptor II (TGFbetaR-II). MFG-E8 in the microvesicles was reduced when cultured in the low-glucose medium or cultured in the high-glucose medium with antioxidant N-acetyl cysteine.

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In the animal model, humid air inhalation, procaterol and ipratropium completely prevented hyperventilation-induced bronchoconstriction, but cromoglycate caused only partial prevention. To study the role of Helicobacter pylori (HP) persistence in generation of gastric mucosa adenoma. Intravascular lymphomatosis should be considered in patients with a combination of rapidly developing encephalopathy and focal neurological signs.

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The effects of phosphorylation at Ser40 of rat tyrosine hydroxylase on the affinities of catechols have been determined with both the ferric and ferrous forms of the enzyme. The resulting estimators are shown to be consistent and asymptotically normal, with a closed form for the variance-covariance matrix that can be used to obtain a plug-in estimator. Rat cerebellar prostaglandins were not modified by the convulsant agent at either dosage. Under conditions of iron deficiency, graminaceous plants induce the expression of genes involved in the biosynthesis of mugineic acid family phytosiderophores. Use of lysimeters to estimate leaching of pesticides in agricultural soils.

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Neurons and ecdysteroids promote the proliferation of myogenic cells cultured from the developing adult legs of Manduca sexta. Relative influence of 129I sources in a sediment core from the Kattegat area. Effect of opiate peptide dalargin and des-Tyr-dalargin on cardiac pump function during ischemia-reperfusion. Development of a bioremediation process by biostimulation of native microbial consortium through the heap leaching technique.

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In this report, the TNM classification and TANIS system were compared to evaluate this prognostic ability. We used four different immortalized endothelial cell lines to study dynamic interactions with lymphocytes. Translocations and inversions involving a chromosome band 14q32 were extremely common abnormalities reported in PTL and ATL/L. Permanent slow waves were recorded on the electroencephalogram in all patients, even during bursts of abnormal movements.

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32D-derived monocytic leukemias showed hits in Pim2 and Max proto-oncogenes, or the chaperone Hspa4, plus additional signaling genes. The aim is to distinguish between cell nuclei with a positive staining reaction and other cell nuclei, and to make it possible to quantify the reaction.

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The objective of this study was to develop, pretest, and validate a questionnaire to measure quality of life in children with seasonal allergic rhinoconjunctivitis (SAR). The authors developed a novel treatment unit for administering such therapy. To understand the role of proteolysis by FtsH and mechanisms leading to leaf variegation, we characterized the second-site recessive mutation fu-gaeri1 (fug1) that suppressed leaf variegation of var2.

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The importance for the Rho GTPases Rho, Rac, and Cdc42 for the heterogeneity of the actin cytoskeleton is well documented. Furthermore, intraperitoneal injection of lipopolysaccaride (LPS) to induce TNF-alpha expression also accelerated hepatic fat accumulation.

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Immunoblot examination of humoral response of chickens infected with Mycoplasma gallisepticum at various ages. Human Oesophagostomum infection in northern Togo and Ghana: epidemiological aspects. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.

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The molecular approach proved versatile and capable of providing useful epidemiological data which could be used to investigate and interpret coccidiosis outbreaks. Intrahepatic venous shunts between the portal and hepatic veins are very rare and only some are considered congenital. Plasma zinc, copper, leptin, and body composition are associated in elite female judo athletes. The relationship between decreased platelet serotonin and the number of serotonin transport channels in the platelet membrane was explored indirectly by measuring the number of the closely associated imipramine binding sites.

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A water challenge produced hives but serum histamine levels did not change. Glycoprotein Ia C807T gene polymorphism and increased risk of recurrent acute coronary syndromes: a five year follow up. We use a low-dimensional, agent-based bubble model to study the changes in the global dynamics of fluidized beds in response to changes in the frequency of the rising bubbles. The intrinsic defect is refractory to regeneration and is not associated with RIF.

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Hemodynamics of carotid artery atherosclerotic occlusive disease. In many cell types polarized transport directs the movement of mRNAs and proteins from their site of synthesis to their site of action, thus conferring cell polarity. Genetic distances estimated from DNA fingerprints in crosses of white Plymouth Rock chickens. We addressed this question using knockout mice that lack G protein alpha(i2), alpha(i3), or alpha(o) specifically. Initial cellular infiltration by polymorphonuclear leukocytes (PMN) is a consequence of the deposition of immune complexes at discreet sites in the glomerulus.

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Fluorescent PCR was used to amplify 9 short tandem repeat loci simultaneously in 40 plasma samples of 10 pregnant women, and genomic DNA samples from their husbands were amplified by the same method. We studied mitochondrial DNA (mtDNA) replication and transcription in association with major hepatectomy. A contralateral patent processus vaginalis may be present in a surprising number of young patients being evaluated for a known inguinal hernia. Interestingly, phylogenetic analysis using Populus trichocarpa revealed evidence for small RNA-mediated regulatory mechanisms within a similarly expanded group of PPR genes.

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Interaction of the biotinylated gramicidin channels with (strept)avidin has previously been shown to result in the appearance of a long-lasting open state with a doubled transition amplitude in single-channel traces and a deceleration of the macroscopic current kinetics as studied by the sensitized photoinactivation method. Occupational and environmental mesotheliomas due to crocidolite mining activities in Wittenoom, Western Australia. This study has shown that upper airway obstruction is a fairly common complication in the post-anesthesia recovery room and that laryngospasm is the most important aetiology.

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Beam-breakup suppression in a multistage klystronlike free-electron laser: Linear detuning. Prognostic value of coronary calcification and angiographic stenoses in patients undergoing coronary angiography. Heat shock proteins not only can protect host cells against heat stress, they can also enable freeze tolerance as well.

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Under the same conditions, the nondeficient variants B and A undergo folding to produce active dimers with normal mobilities in native gels and normal kinetic properties. Recently, a surface population of Pseudomonas putida bacteria was shown to evolve rapidly by natural selection of better-adapted variants in a mixed-species biofilm consortium (S. These results, together with previous reports of impaired hematopoietic responses to GM-CSF and IL-3 in patients with T1D and in NOD mice, indicate that functional deficiencies of these cytokines contribute to diabetes.

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Lettuce and radishes were planted in sludge- or effluent-flooded soil. reconstruction frequently resulted in radiological sequelae but were usually asymptomatic. Moreover, in the same animals, diabetes decreased lumbar DRG 68-kDa neurofilament mRNA mean steady-state levels by more than half. Models of basal ganglia function and pathophysiology of movement disorders. Some epidemiologic factors and diagnostic tests in blastomycosis, coccidioidomycosis and histoplasmosis.

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A five-page questionnaire was sent to 391 neurologic department heads. No long-term changes in metal concentrations are found in sediment cores, except in the middle estuary (Zn, Cu) due to the development of mining activities on an industrial scale in the 1860s. One hundred fifty-five of the 201 subjects (77 percent) changed their minds at least once when given the same scenario but a different description of the intervention.

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An important research area, related to the control of therapeutic efficacy and efficiency, are the studies that aim to establish the decrease in hospital and home care costs as a consequence of speech-language intervention with patients with oropharyngeal dyspahgia. For larger lesions, the treatment was more complex and combined stronger and also more dangerous agents like absolute ethanol and Histoacryl. To investigate the mechanisms of Ca channel modulation, we compared the G-protein-dependent facilitation of three neuronal Ca channels. These cells express high levels of adenosine A(2A) receptors, which are involved in various intracellular processes, including the expression of immediate early genes and regulation of the dopamine- and cyclic AMP-regulated 32-kDa phosphoprotein DARPP-32. This study investigated vein graft neointimal cell origins using a model of vein-to-artery cross-transplantation between transgenic Rosa26 mice (constitutive expression of bacterial beta-galactosidase marker gene) and wild-type mice.

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These low-dimensional methods are not always adequate in the context of conformal radiotherapy. Since radiologic examinations are usually avoided in pregnant women, mainly because of the radiation risk to the fetus, little is known about the effect of pregnancy on cerebral blood flow and metabolism. In the RA synovium, receptor activator of NF-kappaB ligand (RANKL) which is expressed by T cells and fibroblast-like synoviocytes (FLS) and macrophage colony-stimulating factor (M-CSF) which is expressed by FLS induce the differentiation into osteoclast from macrophage-like synoviocyte.

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The reproductive performance parameters have also been compared with the other available studies. Differential influence of interleukin-12 in the pathogenesis of autoimmune and virus-induced central nervous system demyelination. Ectodermal dysplasia (ED) is a group of heterogeneous disorders that result in hypodontia. To describe an optional method for performing decompressive craniectomy using in situ hinge craniectomy technique in patients with traumatic brain injury and stroke.

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Effects of systemic resiniferatoxin treatment on substance P mRNA in rat dorsal root ganglia and substance P receptor mRNA in the spinal dorsal horn. However, with regard to the principles of surgical oncology, tumor-free resection margins are important and radical surgical procedures are justified in selected patients. Crushing resistance and levels of pigmentation were significantly higher in habitats dominated by aquatic macrophytes, and both traits are phenotypically correlated. Inaccuracies or errors present in the image coordinates generated differences among the six solutions. In two of the patients various immunological tests have been carried out (Coombs test, lymphocyte-migration inhibition, serum and urine immunelectrophoresis) that, by their alterations, provide some elements indicating the immunological origin of the phenomena.

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Hydrolysis-resistant nucleotides were introduced into aleurone protoplasts during transfection with reporter gene constructs. We compiled the consecutive cystectomy experience of 16 experienced surgeons during the last 3 years (2000 to 2002) from 4 institutions. The cleavage specificity of the newly discovered protease(s) suggests that the in vivo truncation of alpha A-crystallin reported earlier may be due to the action of proteases. Previously, these outcomes have been attributed to the adoption of different response-preparation strategies when response pairs are constant (low response-pair uncertainty) versus when they are varied from trial to trial (high response-pair uncertainty). This suggests that the neural drive was not affected in the patellofemoral pain syndrome patients.

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There is a place for the use of chronic oral or transdermal opioid analgesics in the treatment of some patients with CLBP. A stable solution is obtained by solving the complete system of equations with an adaptive choice for the number of modes in each layer. We describe a patient who presented with acute recurrent pancreatitis that was attributed to an intrapapillary pedunculated villous adenoma.

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We now show that 3T3-L1 pre-adipocytes secrete active inhibitory molecules which inhibit DNA synthesis in SP1 cells. Additionally, we propose a number of experiments for testing other predictions and further improve the identification of the network structure. Sensitization of osteosarcoma cells to apoptosis by oncostatin M depends on STAT5 and p53. Redox state of single chain Fv fragments targeted to the endoplasmic reticulum, cytosol and mitochondria.

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Feedback from participating laboratories included over 37,500 qualitative and 33,000 quantitative responses, which were analyzed to determine individual laboratory proficiency levels. The possibility of using myocardial necroses in rats, induced by the application of isopreterenol, as a model for the experimental study of new heart and coronary drugs, is discussed. The effect of radiation on cell cycling was investigated using bromodeoxyuridine uptake. ONOO-, superoxide dismutase (SOD), Nomega-nitro-l-arginine (l-NNA), or oxyhemoglobin were added to the tissue baths. The present analysis has been compared with results of former studies, differences are discussed.

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The production of insulin-like growth factor-I (IGF-I) in extrahepatic tissues supports both autocrine and paracrine functions and is regulated differently from that in liver, which supports endocrine function. Replication of the rotavirus genome involves two steps: (i) transcription and extrusion of transcripts and (ii) minus-strand RNA synthesis in viral complexes containing plus-strand RNA.

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Asymmetries between left and right receptive field position, on and off regions, and intra-receptive field wiring are believed to be the neural mechanisms of disparity detection. As parathyroid tumor cells increase replication, PTH mRNA is reduced. The serum concentration of total ketone bodies was increased on day 7, and that of triglycerides was decreased on day 14. The yield of virus (Lsc 2ab) per cell and per unit of surface growth area were observed to be significantly higher in the perfused system than in parallel stationary bottle culture controls--by factors of three- and five-fold, respectively.

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The strain rates were essentially constant over most of the strain range and fill a three-decade gap in the data from existing methods. By contrast, there were no alterations in any of the markers of collagen synthesis in veins, where blood pressure was only slightly elevated. Monte Carlo simulations are performed to obtain the quantitative behaviour of confocal fluorescence imaging in turbid media. The loss angle is measured and real and imaginary parts of (formula: see text) are determined.

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Male NAR are less hyperlipidemic and are resistant to developing renal damage after uninephrectomy. We examined the language of dyspnea in COPD at different intensity levels of dyspnea. A vesicular skin rash in the inguinal area, and on the abdomen, extremities, and face appeared on day 7-10 postinfection. Further, fluoxetine treatment was associated with augmented NKCA in a subgroup of depressed outpatients exhibiting low NKCA at baseline.

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Multiple bladder biopsy and computed tomography scans at 6, 12 and 18 months proved negative. Characterisation of low free-energy excited states of folded proteins.

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Macrolides have been shown to be extremely effective in the treatment of diffuse panbronchiolitis, improve lung function and symptoms in asthma and CF, and reduce nasal polyps and secretions in sinusitis. Each catchment was surveyed and soils sampled to characterize the chemistry of the main soil units. ED visit rates and patterns are similar in the United States and Ontario, Canada.

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Furthermore, when an additional inside-out signal for fibronectin adhesion is unnecessary such as with HPB-ALL T leukemic or phorbol-myristate-acetate-treated normal T cells, neomycin treatment does not alter adhesion or morphology. Most of the methods reviewed here are based on chromatography combined with mass spectrometry detection. Female enrollment in colleges of osteopathic medicine: five years and five percentage points behind.

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Fetuses with an antenatal sonographic diagnosis of clubfoot often have other anomalies, aneuploidy, or both. Yeast on drugs: Saccharomyces cerevisiae as a tool for anticancer drug research. Differentiation of Clara cell (distal type) antigen in human fetal bronchial epithelial cell line (HFBE). Recent discoveries include advances in lesion classification, identification of B cell clonal expansion in the central nervous system with evidence of antigen targeting, identification of chemokines in MS lesions, and expansion of information on the roles of autoantibodies and complement.