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Asphyxia remains the main cause of death along with hypoxic brain injury and hypothermia. The SDF-1-CXCR4 expression pattern suggested that SDF-1-CXCR4 signaling was important for guiding migration by sensory cells known as the migrating primordium of the posterior lateral line. Suggested is the strong possibility that cigarette smoking enhances the neovascular form of AMD risk in late middle aged males, though the magnitude of risk by smoking variables might be overestimated, in part, because of health oriented controls.

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Pancreatic cancer is the fifth most common cause of death due to cancer. Rapid rates of uptake and release of relatively less lipophilic lower-chlorinated PCBs were observed in the mussels, indicating that the primary mechanism of bioaccumulation of lipophilic pollutants in P. The power of practice: harnessing patient outcomes for clinical decision making. We predicted that non-specific physical symptom complaints would correlate more strongly with pain-related distress than with general measures of distress, and that they would contribute directly to disability. In response to a paper (Hawkins, 1992) arguing that self-efficacy is a predictor but not a cause of behavior, Bandura (1995) has raised a series of counter arguments.

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Mildly hyperglycaemic patients should preferably be treated with metformin, acarbose or thiazolidinediones (which are not associated with any hypoglycaemic risk), while more severely hyperglycaemic individuals should receive a sulphonylurea. Here a model based upon their geometric stochastic approach has been derived in closed form. We are unable to clearly identify a group who would benefit from more aggressive local therapy. We conclude that the total number of copies of the short arm of chromosome 12 in the tumors is most probably a factor contributing to the LDH-1 activity released from the tumors. The basement membrane contributes to both the tissue-specific lactational function and survival of mammary epithelial cells, possibly through a similar beta 1-integrin-dependent mechanism.

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Clonidine, at a dose (0.05 mg/kg s.c.) that prevents the cerebrocortical neurotoxic effects of MK-801, decreased sensitivity to the thermal stimulus equally under all conditions (ligated, sham ligated, unoperated), but did not specifically relieve neuropathic pain in the ligated limb. Time-critical care of seriously injured patients is gaining more and more significance. We used this technique for several reconstructive procedures in more than 30 cases.

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We have isolated and characterized from human prostate novel splice variants of the human alpha1A-adrenoceptor, several of which generate truncated products and one isoform, alpha(1A-4), which has the identical splice site as the three previously described isoforms. Three decades of roentgen-diagnosis of the upper digestive tract in the light of modern endoscopy In the presented model a novel search hypothesis is proposed to incorporate angle and amplitude information of an external input vector to decide whether the input matches the long-term memory (LTM) weights of an active node or not, and the embedded NO retrograde mechanism makes the search procedure a closed loop, which improves the stability and convergence speed of the transmitter releasing mechanism in a synapse.

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A rapid polymerase chain reaction (PCR) method was developed for detection of Listeria monocytogenes in foods. A massive terraced village complex in chihuahua, mexico, 3000 years before present Breast implants are not at high risk of sepsis, in contrast with prosthetic heart valves.

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Kicked quantum rotator with dynamic disorder: A diffusive behavior in momentum space. Neurosurgical treatment of spasticity: selective posterior rhizotomy and intrathecal baclofen.

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The current political changes in South Africa have focused attention on matters such as the availability of medical and psychiatric services for all. Recent studies suggest that mitochondrial permeability transition is the central coordinator of PCD and deciding whether or not a cell will die. Alcohol-based handrub is the new standard for hand hygiene action worldwide and usually requires a system change for its successful introduction in routine care. Changes in nerve conduction and Pi/PCr ratio during denervation-reinnervation of the gastrocsoleus muscles of rats. In this prospective, randomized, controlled study, of 81 patients who experienced unexplained failures of IVF-ET despite having good-morphology embryos, 40 received danazol (400 mg/d orally for 12 weeks) following the unsuccessful IVF-ET cycle.

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The computer-generated sequence of randomised assignments was stratified by centre, allocated participants in blocks and was concealed using a centralised telephone facility. Development of bombesin analogs with conformationally restricted amino acid substitutions with enhanced selectivity for the orphan receptor human bombesin receptor subtype 3. Isolation and characterization of cytoplasmic inclusion bodies from the grey matter of the formalin-fixed brain from new case of generalized sphingolipidosis with failure of myelination.

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The results agree with the experimental data, showing that the phonation threshold pressure is minimum when the vocal folds are slightly separated in a near rectangular glottis. We overexpressed CC10 cDNA in the non-small cell lung cancer cell line A549 to determine its effect on the neoplastic phenotype.

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Two-dimensional configuration of the myoneural junctions of human masticatory muscle detected with matrix electrode. In all instances, the reaction product was found in the cytoplasm, but it was also present in the nuclei of some tumor cells. However, the effects of these lasers at standard fluences on atypical melanocytic lesions have not been examined.

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Patients with cancer produce specific autoantibodies against protein antigens present in limited amount among a large background of immunoglobulins (Igs), nonrelevant as biomarkers, including natural antibodies. The onset of leukoplakia usually takes place after the age of 30 years. A higher free radical-generating activity of the mutant enzyme led to the release of copper ions from the damaged protein. When examined in an electron microscope, these revealed patchy myocytolysis with loss of band structure.

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The causes and prognostic significance of low hemoglobin levels in tumor patients. The wetting characteristics on the patterned surfaces were studied by contact angle measurements. Antibodies reactive to the lung-homing domain of metadherin and siRNA-mediated knockdown of metadherin expression in breast cancer cells inhibited experimental lung metastasis, indicating that tumor cell metadherin mediates localization at the metastatic site.

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In antral follicles, immunostaining was observed only in cumulus and mural granulosa cells, whereas theca cells and oocytes exhibited very little or no detectable staining. Studies on olfactory receptor (OR) pharmacology have been hindered by the poor plasma membrane localization of most ORs in heterologous cells.

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We have obtained the cases for the review through a computer search with the system SilverPlatter 3.11 (SilverPlatter Software Copyright NU 1992). Implementation by team members and hospital staff included policy development, staff education, acquisition of funding, a visiting professorship, development of a lactation consultant coordinator and team, and patient surveys to evaluate the program. To evaluate the role of polytetrafluoroethylene (Gore-Tex) as a ureteral substitute in dogs after resection of a 5 to 8-cm-long middle segment. Xth Congress of the European College of Neuropsychopharmacology. Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality.

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Percoll may offer advantages in terms of the quality of the selected spermatozoa that may influence the outcome of assisted conception techniques. Primary tubule cell cultures, obtained from kidneys of TGF-beta1 knockout mice and their wild-type littermates, were treated with exogenous TGF-beta1 or high glucose. The strongly positive correlation between dose ratio and previous morphine dose suggests the need for a highly individualized and cautious approach when rotating from morphine to methadone in patients with cancer pain. Results revealed that spatial judgments were affected by manipulation of the relative spatial positions of the two target symbols and by the interaction between relative position and viewing orientation.

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No differences were found in depression severity, specific depressive symptoms, or suicidal behavior. There is a strong correlation between the potency of the compounds and the difference between the ab initio energy at 90 degrees and the global minima energy for given compounds. Fetal cells can be found in the maternal circulation in most pregnancies. To our knowledge, this is the first time that a combination of aspirin and glyceryl trinitrate (GTN) has been used in the prophylaxis of preeclampsia and fetal growth retardation, and their use associated with not only Doppler screening of the uterine arteries but also regular Doppler follow-up of the fetal arterial and venous circulation.

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There was a significant trend toward less intoxicant testing in recent years. We have explored these associations in patients with chronic heart failure, taking into account the hyperuricaemic effects of diuretic therapy and insulin resistance. Although double reading has proved effective in reducing errors, there is a national shortage of film readers in the screening programme, and recent extensions to the programme have exacerbated this problem.

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Right ventricular involvement was determined from superimposition of the 45 degree left anterior oblique thallium-201 and technetium-99m pyrophosphate images. In heart sections mRNAs transcripts for all three receptors were colocalized in smooth muscle cells of coronary vessels, while no specific positivity was apparent in myocardium. Apoptosis in the developing tooth: association with an embryonic signaling center and suppression by EGF and FGF-4. Although endurance training increased the expression of HSP72 in all of the tissues examined, this induction was less pronounced in diabetic rats than in nondiabetic controls. The effect of multiple plasmapheresis on levels of apolipoprotein B, fibrinogen and cholesterol in blood donors

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This study of Kansas drinking water supply lakes evaluates the relationship among THM formation potential (THMFP), organic carbon and lake trophic state (LTS). The same study also showed positive results of a rehabilitation programme for these women. PMT increased bone resorption 24 h after its addition and always had to be present to express an effect. Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. Emergency endoscopy in upper gastrointestinal bleeding at a second level unit: clinical results and quality assurance (QA), three year experience.

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Of the patients 40 underwent laparoscopic lymph node dissection and 34 did not. Failure to activate cytosolic phospholipase A2 causes TNF resistance in human leukemic cells. Post-translational processing of murine IL-1: evidence that ATP-induced release of IL-1 alpha and IL-1 beta occurs via a similar mechanism. High estrogen-level, which gives a high expression of nitric oxide synthase in the muscle, accentuates the situation. Parents of 228 children with asthma were recruited from diverse clinical practice sites and asked to report on the level of education received in key content areas the National Asthma Education and Prevention Program identified as critical.

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Our data suggest that among the three putative long-chain fatty acid transporters, FAT and FATP appear to have physiological roles. Geometrical properties of Maslov indices in the semiclassical trace formula for the density of states. In the rabbit, in which most axons are myelinated as they traverse the optic nerve head, organelle accumulations were observed only in a sparse population of unmyelinated axons.

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Previous reports suggest that postmenarcheal maturation and the presence of a vaginal foreign body contributed to water slide injuries in women. Evaluation of taurine metabolism in cats by dual stable isotope analysis. We report the weight, stature, body mass index (BMI), and muscular strength of men about 19 years old who have cleft lip, either with or without cleft palate (CLP), or cleft palate only (CP). Although hypercalcemia may cause drowsiness, lethargy, weakness, confusion and coma it rarely causes seizures or cerebral infarction.

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Clearly, there is a need for alternative strategies for the treatment of cardiovascular disease. In contrast, the Fbw7 pathway targets cyclin E for degradation, and Fbw7 mutations occur commonly in cancers. Only when two particles are positioned symmetrically to the centerline to a very high accuracy can the flow be blocked by two particles completely. To explore potential side effects, this study investigated their influence on cognitive functions comparatively by means of a standardized neuropsychological test battery assessing several cognitive domains.

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subtilis groups for cytotoxicity, and to discuss the presence of cytotoxic Bacillus spp. Inoculation of bacterial suspensions into the colonic wall increased tissue TGF-beta1 and collagen content.

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The mode of synaptic linkage in the cerebro-ponto-cerebellar pathway investigated with intracellular recording from pontine nuclei cells of the cat. The same antibodies absorbed onto isolated STE where similar rodlets were evident. Unlike other members of this kinase family, Rlk lacks a pleckstrin homology (PH) domain near the amino terminus and instead contains a distinctive cysteine string motif.

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The effects of iron deficiency on the absorption of different dietary sources of iron were studied, together with the interactions between iron, calcium, phosphorus, magnesium, copper and zinc in the jejunum-ileum of control and iron-deficient rats. Anomalous interface roughening in porous media: Experiment and model. In advanced or chronic infection, a more radical approach seems favorable. Role of NF-kappaB in constitutive expression of MAIL in epidermal keratinocytes.

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Our results suggest that the reversible phosphorylation of the regulator protein plays an essential role in the regulation of phosphorylase-phosphatase activity. In all recipient eyes, DM could be easily and completely removed from the posterior corneal stroma. PACAP38 produced severe bradycardia after transient tachycardia.

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Importance of the enzyme-linked immunosorbent assay (ELISA) for the serologic diagnosis of tuberculosis UTILITY OF THE SELLEK-FRADE REACTION IN HEPATIC DISEASES AND CONSIDERATIONS ON ITS BEHAVIOR AFTER PREDNISOLONE THERAPY

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Treatment with the cell-permeable PKCzeta-specific inhibitor pseudosubstrate peptide inhibited LH-or forskolin-induced NGFI-B expression, indicating the essential role of PKCzeta. Trauma-induced immune dysfunction: a challenge for critical care. These results demonstrate that a single trial of fear conditioning alters sleep-wake states and EEG oscillations over a 24-hr period, supporting the idea that sleep is modified by experience and that such changes in sleep-wake states and EEG oscillations may play a role in memory consolidation.

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Significant elevation of interleukin-10 concentrations was found in ascites but not in plasma in the patients. All hospitalizations identified for a cohort of AIDS patients diagnosed during 1987 in 40 Massachusetts hospitals were included. Evidence is steadily accumulating which indicates that the patterns of T cell reactivity against the environmental antigens that determine the allergen responder phenotype in adulthood are, in many cases, established during infancy. Both all causes and coronary mortality were indirectly related to the score of physical activity.

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Three groups of in vivo feline models were subjected to 3 cyclic load levels in a series of 6 periods of 10 minutes of work spaced by 10 minutes of rest followed by 7 hours of rest. This paper describes the design and process evaluation of a physical activity intervention, from a randomised trial (RT) that examined the effectiveness of delivery modes (face-to-face, Internet-mediated (combined Internet and face-to-face) and Internet-only). Inhibition of tomato proteases by EPI1 could form a novel type of defense-counterdefense mechanism between plants and microbial pathogens. (1) The role of the family in genetic AD research differs from its role in other biomedical research into AD.

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In order to improve the efficiency and to facilitate the LO procedure, some special specimen mounts that hold both the specimen and the support post at the appropriate working distance have been developed. The data suggest a strong relationship between hematological/biochemical adaptation and life style. Our aim was to evaluate its reliability in ulcerative and tumour-like conditions arising in the skin of the head and neck. HLA-DR3 molecules isolated from T2 transfectants can be efficiently loaded with antigenic peptides by exposure to a low pH in vitro, perhaps reflecting the in vivo conditions in which peptides associate with class II molecules.