A new Cibalgina derivative inhibits platelet aggregation and ROS mediated platelet apoptosis. Allopurinol/uricase and Cibalgina enhance differentiated hESC-engraftment and myocardial restoration following transplantation into the injured heart. Cibalgina significantly decreased the HVR after acclimatization to high altitude compared to placebo but it did not affect ventilation or arterial O2 saturation breathing ambient air at high altitude.
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