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Alcohol use may worsen HCV-related liver disease and interfere with adherence to antiretroviral therapy (ART) and medical care. Accelerated phase of chronic myeloid leukemia presenting with hypercalcemia and a mediastinal mass. In primary tumors, such as cervix carcinomas, head and neck squamous cell carcinomas or rectum adenocarcinomas, elevated lactate levels as a mirror of a high glycolytic activity, are correlated even at the initial diagnosis with a high level of malignancy as indicated by increased formation of metastases or an elevated radiotherapy resistance. This study suggested that Coptidis Rhizoma could protect against ONOO(-)-induced oxidative damage and that this effect was mainly attributable to the constituent alkaloids, especially berberine. The human recombinant CRE-BP1 was phosphorylated by protein kinase C and cyclic AMP-dependent protein kinase.

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The use of very small preliminary panels to predict the effects in larger panels using different volunteers was only of limited value as each volunteer was found to have different irritant thresholds. Chromic-acid formaldehyde fixation of nucleic acids of bacteriophage phi6 and infectious bovine rhinotracheitis virus. Genetic mutations involving oncogenes and tumor-suppressor genes occur in carcinogenesis, and may affect biologic behavior of neoplasms.

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These data indicate that the memory T cell repertoire is composed of a surprisingly diverse set of T cell clonotypes with a limited potential for expansion. The patient reported mediated improvement after surgery and on a follow-up visit was doing well without any neurologic sequelae. The nontumorous liver appears more tolerant to internal radiation than external beam radiation. A flowchart with preventive measures for OHSS is presented derived from the available literature.

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Fourteen pancreatic cancer cell lines and 3 pancreatic cancer surgical specimens were studied for their expression of FasR and FasL by flow cytometry, immunoblotting, and immunohistochemistry, FasR function was tested with an anti-FasR antibody. Apoptosis as a mechanism of cell death in liver allograft rejection. Furthermore, neutralizing anti-Fas IgG Ab failed to inhibit chemotherapeutic drug-induced apoptosis in CEM cells. What should be first considered in the treatment of epileptic patients: control of seizures or increase of quality of life?

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Dinoseb degradation involves reduction of the nitro groups to amino groups followed by replacement with hydroxyl groups. The use of fresh frozen allogeneic bone for maxillary and mandibular reconstruction.

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Modified Lundie loops appear to be helpful in improving the functional health of patients with eyelid apraxia. Polyclonal preparations of anti-tetanus toxoid antibodies derived from a combinatorial library confer protection. It can be caused by a posterior dislocation of the mandibular condyle associated with a fracture of the tympanic bone. This approach to protein minimization should be applicable to other proteins composed of architecturally related subunits, including those that might have arisen by gene duplication.

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Train-of-four stimulations were applied to the ulnar nerve at the wrist in both groups. Thus, IP agonists inhibition of PMA induced megakaryocytopoeisis in HEL cells may involve a cAMP dependent pathway.

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Treatment involves cleaning the canal thoroughly and instilling ototopical broad-spectrum antibiotics. Rapid gain adaptation affects the dynamics of saccadic eye movements in humans. Increase in lipid fluidity of cellular membranes induced by adsorption of RNA and DNA virions.

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A novel method of gene resolution analysis of copy number variation (graCNV) yields high-resolution maps of DNA copy number changes and is applicable to a broad range of organisms for which commercial oligonucleotide expression microarrays are available. Linear measurements made using both techniques from many cerebral structures were compared using a paired t-test.

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Angular distribution of ejected electrons from autoionizing 3pns states of magnesium. We have tested this scanner for accuracy, systematic errors and the training required to use it. The present results are discussed with respect to psychobiological theories concerning facial expression.

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Confocal microscopy, computer modeling, and quantification of glomerular vascular corrosion casts. Diastolic blood pressure was elevated immediately after inflation and remained so until deflation in each trial. Study of microsomal mixed function oxidative demethylation and deformylation of 4-methyl and 4-hydroxymethylene sterols.

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Measurement of plasma total homocysteine by HPLC with coulometric detection. However, because of the limited number of studies available, this evidence should still be interpreted with caution.

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It has been shown that PCs of white rat cells inhibit RNA synthesis in the nuclei of intact as well as nephrectomized (unilateral nephrectomy) animals. After discussion of the modern concepts of pathophysiology of ocular myasthenia the ocular symptoms such as ptosis and eye muscle palsies are discussed.

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Cystic fibrosis lung disease is characterized by a self-propagating cycle of obstruction, infection, and inflammation. In office-based practices, the provider office presence is not diluted by competing indispensable activities, and the demand for service is most often for a single type, or stream, of office-based appointment demand.

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The author discusses the utility of ultrasound in investigating the genitourinary tract in neonates, infants, and children, and emphasizes the inter-dependence of ultrasonography and uroradiology. Neonatal alloimmune thrombocytopenia (NAIT) is usually induced by platelet-specific antibodies against HPA-1a (Zwa) or HPA-5b (Bra). Inhibition of the biosynthesis of long-chain n-6 fatty acids was reflected in a decrease in arachidonic acid (20:4n-6) content of serum lipids when fasting, and also in the phospholipid fatty acids of liver microsomes. It is shown here that L-malate enhanced the growth yield at pH equal or below 4.5 while the presence of citrate in media led to a complete and unexpected inhibition of the growth at pH 3.2.

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However, atypical cases are common and the definition of BECT can become blurred. Although the ring-forming peptides have been shown to possess antimitotic properties when tested with cultured eukaryotic cells (and thus have generated considerable interest as possible agents to be used in the treatment of cancer), it is not our intention to extensively discuss the potential pharmacological properties of the peptides. In the present study, environmental samples from seawater, estuarine water, and effluents of sewage treatment plants were analyzed in order to evaluate the role of environmental surface contamination as a possible vehicle for transmission of norovirus genogroups I and II. Tip60 exerts diverse biological functions through mechanisms that are either dependent or independent on its intrinsic histone acetyltransferase activity. We used immunohistochemical techniques to demonstrate the distribution of receptors for the cytokine tumour necrosis factor-alpha on the popliteal lymph node and the adipose tissue surrounding it for 5 d following a simulated immune challenge to one hind leg in the rat.

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This study examined effort on the Word Memory Test (WMT) in groups with differing external incentives. It is argued that any theoretical model of exercise behaviour should take into account the influence of competing personal goals on the initiation and continuation of exercise during leisure time.

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Noncultivable viruses and neonatal diarrhea: fifteen-month survey in a newborn special care nursery. We have developed a technique to purify this enzyme to homogeneity. Effects of hyperglycemia and hyperinsulinemia on satiety in humans.

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TMT exposure on PND5 (Experiment 1) resulted in CS hypersecretion relative to vehicle-injected controls on PND12 and 16 but not PND20. CXCR4 antagonists under development include small-molecule and short-peptide inhibitors. Antigen presentation by CD1 molecules and the generation of lipid-specific T cell immunity. The purpose of this study was to compare the Endo-GIA 30-2.0 mm with the Endo-GIA 30-2.5 mm vascular staple.

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Although the ethnic and clinical characteristics of the two samples were nearly identical, there was a wide variation in the frequency of ACM prescriptions between HK and BJ suggesting that socio-cultural and economical factors as well as traditions of psychiatric practice all played a role in determining the use of ACM. Interaction of cytomegalovirus with leukocytes from patients with mononucleosis due to cytomegalovirus. To critically evaluate these IASs on the basis of their relevant research outcomes. A problem of such an importance as health and future of the nation warrants the state institutes of power to be involved to solve it. For the other four cats, UVN resulted in a pattern of coactivation of the flexor and extensor neck muscles because of a phase change of the splenius capitis.

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Protein levels of PDGF-D were quantified by immunoblotting and immunohistochemistry. Quinupristin/dalfopristin at 0.25 x MIC and vancomycin at 0.5 x MIC separately as well as in combination were added to Trypticase Soy Broth tubes inoculated with a 24 h culture. ras mutations in endocrine tumors: mutation detection by polymerase chain reaction-single strand conformation polymorphism.

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Furthermore, preliminary evidence indicates a presynaptic location of NR2B in some rare cases. It is suggested that administration of lacidipine plus melatonin may enhance the beneficial effects of each drug in essential hypertension.

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External fixation for pelvic stabilization is an important component of the overall treatment of patients with high-energy pelvic fractures. Isolation of TSH-responsive human thyrocytes-analysis of various thyroid tumours. Pathogenesis of foot-and-mouth disease: clearance of the virus from the circulation of cattle and goats during experimental viraemia. Laboratory experiments and atmospheric modeling show that this phenomenon is explained by the efficient uptake of Fe on the ice particle surface.

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Central nervous system lesions were seen in only one of eight suppressed animals at sacrifice 25 days after infection, whereas definite lesions were present in eight of eight infected control animals. Luxatio erecta, or inferior dislocation of the glenohumeral joint, is an extremely uncommon variety of shoulder dislocation. Medical elastic compression stockings (GCSs) are one of the most widely used mechanical compression approaches to relieve venous disorders of the lower limb. A stepwise approach to evaluation of undernutrition and failure to thrive. Other groups have demonstrated that host immunoglobulins are taken up by the cysticerci by adsorptive endocytosis, degraded, and the amino acids incorporated into parasite proteins.

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Clustering of Candida infections in the neonatal intensive care unit: concurrent emergence of multiple strains simulating intermittent outbreaks. Morphologic and histochemical changes in the thyroid gland induced by single exposure to 2,4-DA Northern hybridization detects the expression of three similar brain RNAs approximately 3,900, 3,000, and 2,800 nucleotides in length. In sympathetic ganglia no NOS-immunoreactive neuronal cell bodies could be detected.

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Estrogens protect against hydrogen peroxide and arachidonic acid induced DNA damage. Isolation of the causative enterococcus had been achieved by direct inoculation of the resected valve into the culture medium in theatre.

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major GP63-1 has been reported to contain a glycosylphosphatidylinositol (GPI) membrane anchor while sequence analysis predicted that GP63-6 contained a different hydrophobic C-terminus that may act as a transmembrane region. Peroxynitrite is presumed to be an intermediate in this reaction as the hydroxylation and nitration profiles of authentic peroxynitrite showed similar pH dependence. The difference in prognosis is related in part to the stage of disease at presentation and the ability to undergo resectional surgery. Lamins, together with the lamin-associated proteins of the inner nuclear membrane, are structural proteins in the nucleus that mediate mechanical stress resistance.

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Fungi are a diverse group of eukaryotic organisms whose activities are intricately linked to the lives of human beings. No significant alteration of the IL-2Rp55 subunit occurred with therapy. Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits. Here, we show that after MI, the expression of pro-TRH is induced in the heart coordinately with the protease PC1, an important enzyme in TRH biosynthesis. The co-expression of human PKA with core and human signal peptide peptidase in yeast did not produce phosphorylated NLPs and led to a decreased accumulation of nonenveloped particles.

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Interference with interparietal growth in the human skull by the tectum synoticum posterior. To estimate the frequency and characteristic of sleep disorders and consumption of hypnotic drugs in a population attended by primary care physicians (PC). With reports of greater guantities of c-GMP in psoriatic tissues than in normal tissue, and with the correlation of c-GMP content of cells to proliferation, the effect of mycophenolic acid on cellular c-GMP was investigated.

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Information from 240 patients diagnosed with dermatitis herpetiformis was compiled from hospital records throughout Utah, as well as the sole private dermatopathologist in the state, and from the university referral center of the state. Quantitative structure-activity relationship (QSAR) models of the biological activity (K(i)) of 30 inhibitors of carbonic anhydrase (CA-II) were established using some of the following calculated quantum mechanical descriptors, dipole moment (mu), average polarizability (P), ionization potential (I), electron affinity (A), LUMO energy (epsilon(LUMO)), HOMO energy (epsilon(HOMO)), total energy at 0K (Te), entropy at 298K (S), electronegativity (chi), hardness (eta), electrophilicity (omega), and differences between HOMO and LUMO energies (epsilon(H)-epsilon(L)).

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Movement of tissue relative to fixed regions of interest can result in large variations in apparent T1, with consequent substantial errors in the measured temperature. Bypassing is only possible if the mother is mutant for any of the FIS-class genes, which encode Polycomb group chromatin-modifying factors. Resonance enhancement of electron collision rates for fluorinelike ions. Conversion of lysophospholipids to cyclic lysophosphatidic acid by phospholipase D.