Donaren is used to treat depression. It is thought to work by increasing the activity of serotonin in the brain. Donaren is an antidepressant.

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Molecular-dynamics simulations in systems of rare gases using Axilrod-Teller and exchange three-atom interactions. In addition to providing a conducting coat, it stabilises the tissue against deformations that might otherwise occur during drying, and reduces the extent of tissue shrinkage. More than half of new cancers are diagnosed in elderly patients, but data from randomized clinical trials do not represent the elderly population. Direct measurement of the association of a protein with a family of membrane receptors.

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The two main outcomes were: (1) cardiovascular disease hospitalizations with a discharge diagnosis of coronary (ICD-9-CM 410-414) or other cardiovascular diseases (ICD-9-CM 390-409, 415-448) documented by computerized hospitalization records and (2) death. GI is defined as the incremental area under the blood glucose curve of 50g carbohydrate of a test food expressed as a percentage of the area of the response to an equivalent amount of a reference food (glucose or white bread).

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Furthermore, there are no reported cases where the aorta was closed at the level of the subclavian artery with extra-anatomic bypass to restore blood flow to the lower half of the body. Studies using RT-PCR showed that in these latter species only totally spliced transcripts of PAP are present. The approach is applied to electric-conductivity measurements taken at River Thur, Switzerland, and five wells in the adjacent aquifer, but the method can also be applied to other time-varying natural tracers such as temperature. Patients were stratified on the basis of their neurologic level.

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The purpose of this review is to introduce not only recent clinical trials of PDT for centrally located early lung cancer, but also new applications of PDT for cases of peripheral-type, early-stage lung cancers. Negative margins should be the goal of the operation when achievable with partial pancreatectomy, but the risk of local recurrence is not high enough to mandate total pancreatectomy for microscopic positive margins.

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Furthermore, immunofluorescence studies indicate that the majority of endogenous p52 is colocalized with ASF/SF2 in the nucleoplasm of HeLa cells. Medical options in the treatment of generalised seizures in adults. Phase stability of fluid hard-sphere mixtures interacting through an attractive Yukawa tail.

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Interaction of ultraviolet-irradiated herpes simplex virus type 1 with BSC-1 cells. The pro-sequence displays extensive identity to corresponding regions of other structurally unrelated antibiotic peptides of bovine neutrophils recently cloned.

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It has been established during the past few years that interleukin(s)-1, -6, -11 (IL-1, IL-6, IL-11), and tumor necrosis factor (TNF) can stimulate osteoclast development and thereby the process of bone resorption. The effect of serotonin antibodies on the behavior of C57Bl/6 mice in an open field and on the level of monoamines in the brain structures

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Orotic acid synthesis could be controlled by an induction-suppression mechanism. We further demonstrate a direct interaction between FKBP22 and BiP, the major Hsp70 chaperone in the ER. We studied the therapeutic action of an angiostatic fragment of human thrombospondin 1 (named TSP1ang) on experimental glioma tumor growth. In many periodontal Ruffini endings, S-100beta-IR products were recognized in the cytoplasm of Schwann cells, but not in the axoplasm. Initiation and perpetuation of rat adjuvant arthritis is inhibited by the anti-CD2 monoclonal antibody (mAb) OX34.

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Future policy interventions to improve quality of care among Medicare patients with diabetes should especially target African-Americans. Strangulation colorectal obstruction was modeled in 60 Wistar rats. However, the models have been hampered by the lack of information concerning dyspepsia symptoms, the primary health outcome of the majority of patients seen in primary practice settings. The use of systemic antibiotics in seven community hospitals in Northern Israel. There was no significant effect on the apical GLUT2 component of absorption.

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Development of the mesencephalic trigeminal nucleus requires a paired homeodomain transcription factor, Drg11. These observations demonstrate that endogenous RA acts directly on chondrogenic cells to promote skeletal growth in both embryonic and growing periods, and it regulates the proper formation of cervical vertebrae.

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After reconstruction, all feet had improvement in their weightbearing posture. Randomized double-blind study conducted in selected medical centers in the Philippines from the first quarter of 1999 to March, 2001. The in situ detection of cells undergoing apoptosis is increasingly important in the analysis of injury and degeneration in the central nervous system. Since receptor occupancy cannot account for this phenomenon it is concluded that hCG is exerting a negative control on its own receptors.

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Even though the risk for both RD and an unfavourable result following retinal surgery may be smaller using contemporary surgical techniques, the present study indicates a substantial morbidity following cataract surgery, when a sufficiently long observation period is considered. Pertussis toxin by inducing IL-6 promotes the generation of IL-17-producing CD4 cells. The conception of the role of incompetent calf perforators for the development of leg ulcers advocated by Cockett and others represents a derailment on the way of evidence based medicine. Using this setup, lower protein concentration in the inner particle region was observed even after long equilibration times in protein solution. It is most important to get bacteriologic evidence from suspected patients of pulmonary tuberculosis.

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Model building by comparison: a combination of expert knowledge and computer automation. The foundation for this decision is multifactorial and continually changing as the values of the purchasers and health care consumers evolve.

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Low-molecular heparin Fraxiparine administered as a bolus makes safe and effective anticoagulation during haemodialysis possible and does not call for laboratory follow-up of the anti-Xa level. In contrast to a lesion from a patient with recurrent herpes simplex virus type 2, no message for IL-4 could be detected in any of the syphilis lesions, and 10 of 13 had no mRNA for IL-5 or IL-13. : To determine the association between retinal thickness and visual function in patients with retinitis pigmentosa (RP). Field-induced nonequilibrium periodic structures in nematic liquid crystals: Nonlinear study of the twist Frederiks transition. The presence of MR identifies high-risk patients in whom close out-patient follow-up is warranted, and who may benefit from aggressive adjunctive medical or surgical therapies.

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These injuries cost billions of dollars and expose hospitals and their staff to liability. Third, it allows for outcome-specific exposure effects, so that the specific signs that are affected by cocaine exposure can be identified.

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Moreover, the phosphotransfer reaction between CheA and AlgR was found to be affected by the presence of carbamoyl phosphate, acetyl phosphate, and salts of phosphoramidic acid, recently shown to act as small-molecular-weight phospho-donors in the process of phosphorylation of several response regulators. A total of 470 sealants were placed on permanent molars and premolars. Subsequent genotyping was performed using restriction fragment length polymorphism (RFLP) or microsatellite genotyping analysis, according to the type of VDR polymorphism. Understanding the process of adolescent development is crucial to engendering good compliance.

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It appears that thermoplastics may be the next major breakthrough in terms of a design for a temporary upper-extremity prosthesis. Recent evidence demonstrates that activin-responsive cell lines containing different subsets of these receptors are valuable models for dissecting functional relationships among receptor subtype, signal transduced, and response obtained.

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The same questionnaire was administered telephonically to a cross-section of 586 individuals aged between 18 and 64 years representative of the Autonomous Community of Madrid (Spain) on 2 occasions with an interval of 13 to 32 days. These data suggest that this combination of neuroendocrine hormones is not responsible for the postoperative hypercoagulable state. Development and in vivo evaluation of an implantable left ventricular assist system with an impedance based monitoring and control system.

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The initial clinical experience of using multi-colour fluorescence imaging has shown that the technique has the potential to reveal malignant tumour tissue, including non-invasive early carcinoma and also precancerous tissue. As the number of heart transplantation recipients continues to grow, more cardiac centres are performing heart transplantation and more anaesthetists need to be trained for this exciting and challenging field of anaesthesia.

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Analysis of dioxins and furans in environmental samples by GC-ion-trap MS/MS. In addition, anterior and posterior capsule opacification were assessed. Previously, functional polymorphisms of Hp, coded by the co-dominant alleles Hp1 and Hp2, have been variously associated with several infectious diseases, including malaria susceptibility. Functional significance of three basic N-terminal amino acids of alfalfa mosaic virus coat protein.

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Effect of stem cell factor, interleukin-6, nitric oxide and transforming growth factor-beta on the osteoclast differentiation induced by 1 alpha,25-(OH)2D3 in primary murine bone marrow cultures. All CT studies showed a target pattern with an intraluminal soft tissue mass, an eccentric mesentery, and a slightly dilated intussuscipiens. The first agent of its class licensed for use in panic disorder, paroxetine has been shown to be effective in reducing the number of panic attacks and preventing relapse.

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Activation of soluble guanylyl cyclase by the nitrovasodilator 3-morpholinosydnonimine involves formation of S-nitrosoglutathione. Considerably reduced centrifugation time without increased hemolysis: evaluation of the new BD Vacutainer SSTTMII Advance. Many of the people and events that have contributed to the success of the Proctor Foundation are presented in this brief essay. Anterior open bite with temporomandibular disorder treated with titanium screw anchorage: evaluation of morphological and functional improvement.

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Repeated sputum cultures yielded negative results for acid-fast bacilli, fungi, and other pathological organisms. The Helicobacter pylori protein HorB (encoded by HP0127) is a member of a paralogous family that includes the adhesins BabA, AlpA, AlpB, and HopZ, which contribute to adhesion to gastric epithelial cells. Status epilepticus is a medical emergency and is secondary to a range of insults to the central nervous system. reported on two patients with lissencephaly type I and short, sloping forehead, an atypical phenotype for Miller-Dieker syndrome, a more common lissencephaly syndrome.

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The simulations are used to determine the dependence of the adhesion area on the vesicle volume, the surface area, the bending rigidity, the adhesion energy per membrane area, and the adhesion potential range. These results should serve as a useful benchmark for epidemiologists concerned with the magnitude of exposure in historically dusty industrial tasks. Thus, these results suggest that a decreased cellular level of DNA Topo II and an overexpression of MRP gene may be responsible for the expression of an MDR phenotype in the T24/ADM9 cells and that such non-Pgp-mediated, atypical MDR may develop in bladder cancer treated with chemotherapy including ADM.

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The direct conversion of organic nitrogen into molecular nitrogen also can be achieved using the same catalyst. Development and application of polymerase chain reaction (PCR) tests for the detection of subgroup J avian leukosis virus.

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When comparing the neurochemical responses between the drugs at an equal level of behavioral activation, cocaine was more potent than d-amphetamine in increasing 5-HT in the PFC, while no differences were found in the PRC or EC or in the DA responses in all three cortical areas. Determination of exposure to cobalt and nickel in the atmosphere in the hard metal industry. This paper describes our experience at Mayo Clinic with a new technique for planning ventro-oralis posterior (VOP) ventral intermediate (ventrolateral) VIM (VL) thalamotomy procedures for selected patients with medically intractable tremor. Absolute blood myeloid DC (MDC) and plasmacytoid DC (PDC) numbers were decreased in ND and ED patients compared to age-matched controls. The improved recombinant form of the death ligand Apo2L/TRAIL (Apo2L/TRAIL.0) is not cytotoxic for normal human cells and is a good candidate for the therapy of multiple myeloma (MM), a B-cell neoplasia that remains incurable.

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Synthesis, structural characterization, and thermal stability of a new layered germanate structure, Na4Ge16O28(OH)12. 1 Infusion of isoprenaline into dorsal hand veins preconstricted with noradrenaline produced vasodilatation in four subjects out of five which was reversed by addition of propranolol. Use of monoclonal antibodies to identify serotypes of enterovirus isolates. These findings suggest that the Gli-1 transcription factor plays a key role in BCC development.

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The need for easily accessible computerised decision- and documentation-support in primary health care has been previously published. Densitometric and texture features were generated, and MACs were described on the basis of multivariate discriminant analysis. Accordingly, as a missed diagnosis can have disastrous consequences for the patient, hitherto the exclusion of phaeochromocytoma has typically entailed multiple and repeated tests which are time-consuming and costly.

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It has been shown that senescence is not any more delayed by cytokinin when the expression of the invertase inhibitor is elevated. The effectiveness of growth factor therapy in animal models and in limited human clinical trials has been realized. XNAT follows a threetiered architecture that includes a data archive, user interface, and middleware engine.

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Finally, the unusual charge distribution of the two-domain fragment of MAdCAM-1 is predicted to orient the molecule optimally for integrin binding on the top of its long mucin-like stalk. The ultrastructural modes of lymphatic and blood vessel invasions were studied comparatively in hamsters with squamous cell carcinoma (O-1N) that had a high potential for lymph node metastasis. Different meanings of respite: a study of parents, nurses and social workers caring for children with complex needs. Structure-odor relationships: using neural networks in the estimation of camphoraceous or fruity odors and olfactory thresholds of aliphatic alcohols. To assess whether flutamide (Drogenil), a pure androgen receptor blocking agent, improves survival in patients with pancreatic carcinoma and thus whether testosterone is a major growth factor for this tumour.

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Transitions in dental care coverage: a case study of patient satisfaction in managed care dental plans. Of the four patients with azotaemia, three showed definite improvement to normal levels while one stabilized.

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Using mouse cDNA for PTP beta 2 and PTP epsilon, which we have cloned recently, we attempted to locate the genes to mouse chromosomes. A case of incessant supraventricular tachycardia continuing despite AV block is reported. This well-planned initiative addresses the need to cut healthcare costs in Puerto Rico, but whether it will successfully meet the healthcare needs of beneficiaries in the long run is up for debate. This study evaluated the effectiveness of an escalating-dose regimen of trandolapril in subjects with stage 1 or stage 2 hypertension.

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An immunization strategy that targets both the virus and its CCR5 receptor has significantly inhibited SHIV(89.6P) infection and may serve as a novel strategy in the prevention of HIV transmission. Ultrasonographic findings of perivascular jugular vein diseases in cattle Apoptosis was induced in the spleen but not the thymus of mice administered 1 mg/kg AAL(R), correlating with levels of AAL(R)-phosphate (AFD(R)) in organ extracts.

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Biosynthesis of recombinant human pro-alpha 1(III) chains in a baculovirus expression system: production of disulphide-bonded and non-disulphide-bonded species containing full-length triple helices. In conclusion, the results found with agonists and antagonists are compatible with the view that a 5-HT1-like receptor is involved in 5-HT-induced direct relaxation of circular muscle of guinea-pig stomach fundus. The identification of myogenic cells in skeletal muscle, with emphasis on the use of tritiated thymidine autoradiography and desmin antibodies. Therefore, we assessed concomitant or sequential combinations of low/intermediate concentrations of alpha-IFN or beta-IFN (10, 50 and 100 IU/ml) with a low concentration (0.1 mM) of NaB on a human breast cancer cell line (MDA-MB231), which exhibited a moderate sensitivity to IFN. A similar conclusion regarding increasing multiple myeloma mortality rates in the elderly has been derived using the Strehler-Mildvan modification of the Gompertz relationship.

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One intensivist (A) reviewed the PAC data and recorded a diagnostic impression and therapeutic plan. Appearances were classified according to a physical model of the interaction between sound and collections of gas.