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Corticosterone, 18-OH-deoxycorticosterone, deoxycorticosterone and aldosterone secretion in tissue culture of foetal rat adrenals in the presence and the absence of ACTH. Quantification of apolipoprotein AI-containing lipoprotein particles in non-insulin-dependent diabetes mellitus. The alpha chain of the nascent polypeptide-associated complex functions as a transcriptional coactivator.

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Precision measurements of K and L transitions in xenon: Experiment and theory for the K,L, and M levels. The conformation of peptide thymosin alpha 1 in solution and in a membrane-like environment by circular dichroism and NMR spectroscopy. Further study of the biological functions of DARPP-32 may be helpful for understanding the mechanisms of MDR of gastric cancer cells and developing possible strategies to treat gastric cancer.

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This binding site was identified on the cyanogen bromide fragment alpha 1(I)CB6 of collagen type I, which also binds heparin. The Mo requirement of adults amounts to about 25 micrograms d-1. There was no difference in affinity for CEA among a murine (mT84.66), a mouse/human chimeric form (cT84.66) or a disulfide deleted version (delta SScT84.66) of this antibody. Performing these simulations assuming various anatomic and physiologic conditions an obstetrical-biomechanical data basis could be obtained, that was implemented in a PC-based expert system.

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In this experiment, artificial light and dark signals are provided in a measured sequence at an inappropriate time of year to induce breeding out of phase with environmental photoperiod. Photorhabdus and Xenorhabdus bacteria therefore engage in both pathogenic and mutualistic interactions with different invertebrate hosts as obligate components of their life cycle. A basic understanding of cell culture contamination is necessary to appreciate the need to develop and practice standardized cell culture procedures. An examination of these mutants demonstrated that CDT represents the previously described granulating cytotoxin in H. The study period was 1970-1980, when unemployment was low in Sweden.

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However, corrections in dietary habits do not appear to be consistent with current guidelines and recommendations. These findings could also be important for understanding the process of metastasis. This study was designed to evaluate the effect of HSCT on the patients with CML. In the First World War, horses were an integral part of warfare and while technological warfare was making its debut, conventional wisdom decreed that cavalry horses and pack animals had to be kept in good shape for any hope of victory. Here, we provide evidence that a class of compounds, seco-pregnane steroid glaucogenin C and its monosugar-glycoside cynatratoside A of Strobilanthes cusia and three new pantasugar-glycosides of glaucogenin C of Cynanchum paniculatum, are effective and selective inhibitors to alphavirus-like positive-strand RNA viruses including plant-infecting tobacco mosaic virus (TMV) and animal-infecting Sindbis virus (SINV), eastern equine encephalitis virus, and Getah virus, but not to other RNA or DNA viruses, yet they were not toxic to host cells.

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On the other hand, spiperone and ketanserin, 5-HT2 receptor antagonists, at doses of 3 mg/kg, potentiated the hypothermia and completely suppressed the hyperthermia and mortality caused by tryptophan in the pargyline-pretreated rats. Antioxidant effect of captopril is believed to be due to increase in enzymes of bodily antioxidant defense, such as glutathioneperoxidaze, glutathionereductaze, and elevation in blood levels of vitamin E and reduced glutathione. Tests of linear contrasts on the regression coefficients for time and region show an increase in the magnitude of the difference in the risk of all cause mortality and heart disease mortality between northern and southern regions of the province for the 1985-1989 and 1995-1999 time periods.

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holmesii response regulator BvgA(BH) could not substitute for its B. In addition, recombinant TARPP is not methylated by extracts from Carm1(-/-) cells, indicating that there is no redundancy in this pathway.

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The action of norepinephrine was blocked by propanolol while phenotolamine and haloperidol were relatively ineffective except at highest concentrations. Juvenile idiopathic arthritis (JIA) is the most common cause of chronic arthritis in children, with frequent involvement of the metacarpophalangeal joints (MCPJ). All viruses in the family Potyviridae which have been studied cytologically (currently 111) induce cylindrical inclusions in host cytoplasm. It is concluded that in case of acute aorte aortic dissection, the back-flow of blood should be checked at the time of femoral arterial cannulation, and whenever the back-flow is poor, some procedures should be added to increase distal blood flow. The normal spherodial morphology was destablized into a flattened structure after the in vitro treatment of either the resistant strain 08 or the sensitive strain Bizio.

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The elevated adrenocorticotropic hormone stimulates both the accumulation of precursor steroids in the impeded pathways and excessive steroid synthesis in other adrenal biosynthetic pathways unaffected by the enzyme deficiency. Results of the study are discussed in relationship to the field theory of carcinogenesis as developed for the lower female genital tract. The luminal surface possessed numerous microvilli and long cytoplasmic cell processes which appeared to surround material in the lumen. One cyst could not be visualized arthroscopically and probing of the ACL from the anterior portal resulted in drainage of the cyst. To investigate the effects of gelatin administration on post prandial homeostasis.

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Lysosomal acid hydrolases in established lymphoblastoid cell lines, transformed by Epstein-Barr virus, from patients with genetic lysosomal storage diseases. In order to develop a targeted adenovirus, it is therefore necessary both to ablate endogenous viral tropism and to introduce novel tropism.

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The potency increase did not translate into a reduction in IC50-values for the coagulation assay aPTT and TT, in contrast to the IC50-values for thrombin-induced platelet aggregation. Cellular variables in bronchoalveolar lavage fluids (BALF) in selected healthy pigs. Cerebrospinal fluid gamma-aminobutyric acid was elevated in almost all patients investigated. To determine the prevalence of gestational diabetes mellitus (GDM), glucose intolerance (GI) and macrosomia in a Latin Mexican population, using the one-step procedure proposed by the World Health Organization.

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The sample comprised two groups of subjects: residents (800,000-1,000,000 inhabitants) and all refugees and displaced persons temporarily residing in the Zagreb region (78,000-95,000 persons). Current research is also directed at methods to produce transgenic pigs. The molecules from the arylpropionic family of drugs: ibuprofen, flurbiprofen, ketoprofen and naproxen produced the linear relationship. Our recommendations are directed toward decreasing the incidence of head-down contact.

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The mean airborne concentration of arsenic around various types of joinery machines was in the range from 0.54 to 3.1 micrograms m-3. Effect of HIV-1 nef gene on the relationship of cells in bone marrow and peripheral blood in transgenic mice

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Twenty-four normotensive and 24 preeclamptic women who were similar in age, weight, and mean duration of gestation (35 weeks) were studied. Comparison of different cytologic qualifications of atypical squamous cells of undetermined significance with the frequency of significant cervical disease as documented by tissue biopsy. The model was used to determine the likely distributions of ion conductances in morphologically distinct parts of the MNCs: soma, primary dendrites and secondary dendrites. Nesiritide is US Food and Drug Administration-approved for the treatment of patients with acutely decompensated heart failure who suffer from symptoms at rest or with minimal exertion.

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The authors present the opinion that the mother, having been informed of the risks of vaginal versus abdominal delivery, should be allowed to play an active role in the critical management decisions. Pain of uncertain origin in the jaws should alert clinicians to the potential of metastatic disease in patients with a history of cancer and a bone scintigraphy should be done to rule out metastatic involvement. Surgical excision of solitary toxic thyroid nodules would appear to be the treatment of choice. Policy or educational interventions that seek to alter the situations and settings of underage drinking may be effective in reducing consumption of alcohol in adolescents.

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Here, in human cells, we show that human minichromosomes bearing V(D)J recombination signals are protected well over 100-fold from recombination if they are CpG methylated, providing a rational basis for the karyotypic stability in cells with high levels of V(D)J recombination activity. In contrast, chronic treatment with abecarnil failed to induce tolerance to its own anticonvulsant activity. Multiple early bile duct carcinoma associated with congenital choledochal cyst. We investigated the effects of PHT and the prodrug fosphenytoin in rabbits required to learn a discrimination and reversal of a classical eyeblink conditioning paradigm. The ratio of effect versus predicted effect were calculated for intravenous cyclosporine dosing.

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Therefore, our results suggest that UAER is a reliable index of the activity of the renin-angiotensin-aldosterone system in rats under conditions of low and high aldosterone secretion. Intrinsic properties of a Burridge-Knopoff model of an earthquake fault. Two-dimensional models in quantum field theory: Reduction to the free-particle case. Comparative effects of two dithiocarbamates disulfiram and thiram, on adrenal catecholamine content and on plasma dopamine-beta-hydroxylase activity.

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Enhanced degradation of trypsin-treated low density lipoprotein by fibroblasts from a patient with homozygous familial hypercholesterolemia. A plausible mechanism explaining these observations is proposed in this paper. A plasmid-human IL-10 construct (pMP6-hIL-10) complexed with cationic liposomes was administered by single intraperitoneal injection to healthy mice.

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Rapid convergence to the universal dissipation sequence in dynamical systems. It was concluded that cells from the epididymal fat pad from small rats can be isolated in a homogenous fraction that develops in culture into cells of identical morphology and function as adipocytes formed in vivo. Short- and long-term administration of pentagastrin to fasted and fed female rats did not affect the enzyme activity or enzyme protein level, except for a transient increase in enzyme activity but not in enzyme protein level 12 hours after administration to fasted fats. Pseudoaneurysm of superior mesentery artery branch after renal extracorporeal shock wave lithotripsy: case report and review.

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Achieving higher pathological complete response rates in HER-2-positive patients with induction chemotherapy without trastuzumab in operable breast cancer. Of 9 New Zealand White rabbits inoculated at multiple sc and im sites with a single dose of Herpesvirus saimiri (HVS), 2 developed malignant lymphomas 40-50 days post inoculation. Mutations in the actin binding motif alone did not abolish the activity of CR16 but the mutations in combination with deletion of N-terminal proline rich motif abolished the ability of CR16 to suppress the growth defect.

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Antimicrobial resistance among Gram-positive organisms continues to increase and has reached epidemic proportions in a number of countries and within medical centers worldwide. Pathological-morphological changes in the brain microcirculatory blood vessel in dog after global brain ischemia have been evaluated qualitatively. The metabolic capacity of the BAT, measured as total cytochrome oxidase activity, changes substantially with decreasing temperature of adaptation in all species studied, increasing twice, six times and almost twelve times in the mouse, rat and golden hamster, respectively. The anatomo-radiographic types had an interesting bimodal pattern: Among the benign types: a double fracture of the iliopubic ramus is dangerous for the bladder (1 case), and leads to a dysplastic acetabulum with time (1 case). Self-reported questionnaires were distributed in a cross-sectional study of 1,936 students in public junior high schools in Tokyo, Japan.

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To compare the quality of data recorded by a commercially available clinical information system (CIS) to other commonly used methods for obtaining large amounts of patient data. The investigation reported here was carried out to determine the oestrogen receptor status of metastatic and primary uveal melanomas. To evaluate modification in body weight and anthropometric indexes in women at the time of menopause. Hemoglobin test result variability and cost analysis of eight different analyzers during open heart surgery. Moreover, difficulties in determining the chemotherapeutic response have made accurate determination of the response rate virtually impossible for each trial.

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In high concentrations of fresh nonimmune human serum, Mycobacterium tuberculosis activates the alternative pathway of complement and binds C3 protein, resulting in enhanced phagocytosis by complement receptors on human alveolar macrophages. Oophorectomy diminishes both circulating estradiol concentration and basal release of NO to levels seen in male rabbits. Serum antibody responses to sheep hydatid cyst fluid (SHCF) and a purified Antigen 5 (Ag5) were examined in ELISA, immunoelectrophoresis (IEP) and immunoprecipitation (IP) to facilitate production of monoclonal antibodies (MAb) to E.

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Our results therefore provide a new perspective to the immunogenicity of the idiotypic protein in myeloma. In this study we tested the effect of introduction of FoxP3 into antigen non-specific polyclonal and antigen-specific monoclonal T cells on diabetes development in NOD mice. The highest specific activities obtained were 2750 nmol C2H4 formed . The results of clinical and biochemical investigations on a girl with all obligatory signs of Mauriac syndrome already in infancy were compared with the different hypotheses suggested in order to explain the pathogenesis of this disease. The strong correlations suggest that they may be important risk factors, contributing to the metastatic potential of the tumor.

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We study the interplay between motor programs and their timing in the brain by using precise pulses of transcranial magnetic stimulation (TMS) applied to the primary motor cortex. Mast cell differentiation in the marrow is activated as part of the body response to parasites. It is now well established that an array of CC and CXC chemokine receptors, in association with the CD4 molecule, can interact with the HIV-1 gp120 protein to facilitate viral fusion.

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In contrast, 3beta-hydroxy-5beta-cholest-7-en-6-one is metabolized to 14-deoxy-alpha-ecdysone and a variety of intermediates all lacking the 14-hydroxy group. Novelty seeking and the dopamine D4 receptor gene (DRD4) revisited in Asians: haplotype characterization and relevance of the 2-repeat allele. In addition, HNP-3 and a fragment of azurocidin were found in meconium, whereas the holoprotein azurocidin was detected in feces.

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Current possibilities in the treatment of severe stenosis of the major airways This finding could have implications for potential signaling functions of such a receptor molecule during pro-/pre-B cell development.

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Grafts of 6 mm in initial diameter implanted into the thoracic aortas of mongrel dogs for 3 months also could be dilated in vivo by inflating the PTA four to five times at 15 atm, as found in the vitro study. Mechanisms influencing the postnatal development of the eye, especially their relation to the grade of prematurity and neonatological therapeutical strategies, require further investigations. Binding of a ligand in the extracellular space to a transmembrane receptor constitutes the first crucial step for activation of a signaling pathway within the cell. The aim of the present study was to evaluate the association of contractures with an increase or reduction of non-spastic muscle overactivity due to severe cerebral damage.

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Cannabis, catecholamines, rapid eye movement sleep and aggressive behaviour. Memory of intraoperative events occurring during inhalation anesthesia was not demonstrated with the present methodology in young children. The CMA immunoserum added to culture medium with cysticerci limited the activities of the bladder worms. Antibody repertoire development in fetal and neonatal piglets: XIX.

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A study was made of the structural rearrangement of renal tissues in intravital nephrobiopsy specimens and of the functioning of the renin-angiotensin-aldosterone system and kallikrein-synthetic function in patients with mesangioproliferative (MSPGN) and membranous proliferative glomerulonephritis (MPGN). Finally, it proposes necessary steps by which this shortage can be decreased. Activity of arginine aminopeptidases and phosphatases in inflamed palatal mucosa in denture stomatitis: a histochemical and biochemical study.

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EMSA: a SAAM service for the estimation of population parameters based on model fits to identically replicated experiments. Our results give no indication that wet sulfate inputs are affecting northern red oak height growth across the atmospheric deposition gradient. The patient has no complications such as diabetes mellitus or hypercholesterolemia. A nurse residency program for competency development using human patient simulation.

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Two of these three criteria, however, would expose the physician to criminal prosecution. Clinical and pathological analysis of 100 cases of drug-induced liver injury Twenty eight patients presenting with cervico-brachial radiculopathy secondary to acute soft posterolateral disc herniation were reviewed. Pancreatic islet insulin secretion is increased after resistance exercise in rats. Influence of longer term left ventricular assist device support on valvular regurgitation.

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The improvement of urban air quality achieved by establishing more trees in towns and cities is also illustrated. Private practice refractive surgery center, Delft, The Netherlands. Spontaneous esophageal carcinoma and epithelial cell line of an adult rhesus monkey.

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This might indicate that genetic variations of the serotonin transporter could increase the risk for depression chronification via altering limbic neural activity on a preattentive level of emotion processing. Strains were identified as Mycobacterium tuberculosis complex, Mycobacterium avium complex, Mycobacterium fortuitum, Mycobacterium chelonae and Mycobacterium kansasii in less than 24 hours.

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Association between physical activity and urinary incontinence in a community-based elderly population aged 70 years and over. Effects of vestibular nerve section on sound-evoked myogenic potentials in the sternocleidomastoid muscle of monkeys. Four objects were homologous to the Ty1/ copia family of class I transposable elements, one of which was designated Retropop and interrupted one of the disease resistance genes.

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Independent stimulation of motility and the oxidative metabolic burst of human polymorphonuclear leukocytes. Five additional haplotypes showed higher estimated frequencies in the patients but the differences were not significant. We performed a retrospective chart review of 6 patients diagnosed with nephrogenic systemic fibrosis at our institution.

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Cotton-topped (CT) or white-lipped (WL) marmoset lymphocytes were transformed in vitro with herpesvirus papio (HVP) into permanently growing lymphoblastoid cell lines (LCL). Hemoglobin Bassett produces low pulse oximeter and co-oximeter readings.