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Genozym (Clomiphene)
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The antiproliferative activity of the partial antiestrogens, tamoxifen, nafoxidine and Genozym, and the pure antiestrogen, ICI 182,780, was determined. A randomized controlled trial of the effect of rosiglitazone and Genozym citrate versus Genozym citrate alone in overweight/obese women with polycystic ovary syndrome.

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The capacity to substantially degrade type IV collagen was demonstrated in every pleural sample. but also made it possible for many individual authors to directly publish their own information on the Internet, bypassing traditional publishers and established bibliographic systems. Effect of probenecid on breathing movements and cerebral clearance of prostaglandin E2 in fetal sheep. Expression of low-risk human papillomavirus has no effect on cyclin complexes. However, the sleep electroencephalogram (EEG) montage used in our study was different to that employed by previous researchers.

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We hypothesize that disturbance is propagated through multivariate systems through key variables that transform a disturbance and pass a reorganized disturbance effect to the next hierarchical level where the process repeats until ultimately affecting biota. Filaments deficient in cMyBP-C are fragmented by shear force well tolerated by the stable form.

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Routine second-trimester ultrasound for low risk pregnancies in a South African community. Programmed multichannel electric stimulation in the treatment of patients with diseases of the peripheral nervous system To produce full-length cDNA the two overlapping segments were either ligated or fused by polymerase chain reaction. Analysis by SDS/PAGE of these bands demonstrated that the NADH-induced NBT reduction band contained several polypeptides (PMP32, PMP61, PMP56 and PMP18, where PMP is peroxisomal membrane polypeptide and the number indicates molecular mass in kDa), while the NADPH-induced band was due exclusively to PMP29. Microsatellites or simple sequence repeats (SSRs) occur ubiquitously and show complex patterns in length, motif size and sequence.

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Randomly selected urban HMO enrollees were invited to be tested for HSV-2 antibody at a research clinic. To assess the variability of ultrasonographic measurements at different levels of the abdominal aorta. Deciphering the neurobiological consequences of cerebral cytokine expression in vivo represents an important research objective which has implications for our understanding of the pathogenesis and treatment of many significant neurological disorders. Significant increases of phosphoenolpyruvate concentration in the cytosol fraction and citrate concentration in the mitochondrial fraction were observed.

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Olfactory responses and field attraction of mosquitoes to volatiles from Limburger cheese and human foot odor. After collection of blood from a random sample of the children, vaccine was given twice to all children under 5 years of age.

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The aim of this study was to access the influence of several factors on local control (LC) and overall survival (OS) in patients with early breast cancer after breast-conserving therapy. Epidemiological evidence suggested that they might be the causative agent of hepatitis A. The serum concentration of albumin and creatinine, as well as the metabolic activity of hepatic microsomes towards pindolol, were not altered. If the homogeneity can not be improved, other methods of field matching have to be developed. To review the evolution of mitral valve repair and outline currently favored repair techniques.

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In bilaterally labyrinthectomized rats, the appearance of pERK1/2-immunoreactive neurons was eliminated in the VN. Therefore, electro-physiological recordings provide additional information to the neurological examination when the clinical relevance of a radiologically-suspected LSS needs to be confirmed.

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Jejunal intussusception in a Chinese 10-year-old boy affected by the blue rubber bleb nevus syndrome is presented and discussed. Negative transcriptional regulation of a positive regulator: the expression of malT, encoding the transcriptional activator of the maltose regulon of Escherichia coli, is negatively controlled by Mlc.

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The spacing effect depends on an encoding deficit, retrieval, and time in working memory: evidence from once-presented words. Amisulpride in the short-term treatment of depressive and physical symptoms in cancer patients during chemotherapies.

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Enhanced peripheral thrombogenicity after lung inflammation is mediated by platelet-leukocyte activation: role of P-selectin. The source of the soluble form of SSAO found in the blood serum is unknown. In Arabidopsis thaliana, the Toc159 family consists of four genes: atTOC159, atTOC132, atTOC120, and atTOC90. Despite the differences in heart rate variability, mean systolic blood pressure and its variability profiles were poorly affected by the suppression of heart rate variability.

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Sharp rise in sales of untaxed cigarettes in Canada threatens public health. The purpose of this study was to determine the concentration of 17 beta-estradiol and progesterone in cytosol, nucleic fraction and particulate fraction of term placentae of normal and hypertensive patients by radioimmunoassay. In this case, the Context practice condition seemed to be more transfer-appropriate.

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Variations in hospitalization rates for asthma among black and minority ethnic communities. Feline predatory behavior has no equivalent in man, and therefore its hypothalamic representation probably does not exist in the human brain. Clinical ethics is centrally concerned with the ethics of the encounter between the healthcare professional and the patient in clinical care settings. At the end of both the untreated and treated phases, subjects were given a graded maximal exercise test on a bicycle ergometer. The authors suggest that serologic screening should be offered to all first-degree relatives of patients with CD.

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One trap presented a yeast culture in sucrose solution, while the other contained sucrose solution as control. Changes in pulmonary mechanics after fiberoptic bronchoalveolar lavage in mechanically ventilated patients. hGH 177-191 caused a dose-related potentiation of glucose-induced insulin release, whereas the peptide by itself caused no stimulation of insulin release from the islets. Nucleotide sequence of the phage T5 DNA segment containing six tRNA genes. Antiproliferative effects and mechanism of action of SCH 56592 against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.

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This stable cardiac performance occurs at lower wall stress and thereby more advantageous energetic conditions. Adhesion formation after intraperitoneal and extraperitoneal implantation of polypropylene mesh. In vitro starch digestibility assays use fungal amyloglucosidase to provide this function. The proposed electrodes demonstrate satisfying selectivity for molybdate(VI) ion in the presence of a wide variety of anions other than iodide, and can be used in the pH range 5.0-7.0. In sum, nicotinate is catabolized to yield two CO2 molecules, two acetyl-CoA molecules, and ammonium.

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The cognitive interview: is its benefit affected by the level of witness emotion? Unexplained sudden death, including sudden infant death syndrome (SIDS), in the first and second years of life: case definition and guidelines for collection, analysis, and presentation of immunization safety data. A case series of 71 patients referred to a hospital-based occupational and environmental medicine clinic for occupational asthma. Idiopathic Parkinsonism with Lewy-type inclusions in cerebral cortex. The OLPs fail to differentiate properly is disconnected (disco) mutant embryos, where appropriate connections between the larval optic nerve and its targets in the brain are not formed.

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Barmer district of Rajasthan in Thar desert and hitherto a hypoendemic area for malaria came in the grip of a severe malaria epidemic during 1990. During indentation, the corneas were suspended by clamping the edges of the cornea, thus allowing depth-sensing measurement free from the complication of the backing substrate.

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The legal implications of healthcare communications: what every pain physician needs to know. The aim of this study was to determine the extent to which small-dose ketamine, when used in conjunction with remifentanil, has a morphine-sparing effect in the perioperative period.

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We report the successful outcome of combined intravenous heparin and nitroglycerine in a case of VMT followed by a limited resection of small bowel. Ultrasonic Doppler color flow mapping was performed from the abdominal surface to detect the urine jet phenomenon from the ureteral orifice in 25 healthy men and four healthy boys.

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During the study prostaglandins PGE and PGF2 alpha in serum and fatty acids in serum and erythrocyte membranes were measured. Ap4A may play an important role in kidney perfusion and, thus, in blood-pressure control. Development of effective hydrogen sulphide removing equipment using Thiobacillus sp.IW.

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We retrospectively examined 3 patients with CDL that were treated with endoscopic stenting. Utilizing cryogenic grips for dynamic tension testing of human placenta tissue. We studied the expression of candidate molecules for tissue injury in vasculitic neuropathies immunohistochemically, using samples obtained by nerve biopsy from seven patients with necrotizing angitis.

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It is usually assumed that host cells do not endogenously express the specific receptor under consideration. Significant decreases in the ratio of heart weight to body weight were observed in SHR treated with trandolapril and perindopril, whereas they were not observed with temocapril and enalapril. Determination of PAH sources in dated sediments from Green Bay, Wisconsin, by a chemical mass balance model. The utility of antihistone antibody screening in the diagnosis of drug-induced lupus erythematosus. Potent oral bisphosphonates are the mainstay of therapy for osteoporosis.

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The best model fitting for axial opacities gives a significant positive effect for both linear dose and linear age-related regression coefficients and a significant negative effect for an interaction between radiation dose and age. Concentration-response curves were generated for acetylcholine, calcium ionophore A23187, and sodium nitroprusside (SNP) in isolated phenylepherine-preconstricted pulmonary artery rings (10(-9) to 10(-6) mol/L) 4 hours after endotoxin (500 mg/kg intraperitoneal) or saline injection. A case of fatal varicella zoster infection with refractory abdominal pain as an early symptom.

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Comparison of molecularly imprinted solid-phase extraction (MISPE) with classical solid-phase extraction (SPE) for the detection of benzodiazepines in post-mortem hair samples. Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. Differential effects of monensin on asialoglycoprotein receptor function after short-term ethanol administration.

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Therefore, we studied to what extent the expression of each of the subunits contributes to the regulation of IL-12 production. To further our understanding of the evolution of avian Mhc genes at the genomic level, we screened a cosmid library made from a red-winged blackbird (Agelaius phoeniceus) with a blackbird cDNA probe and subcloned from one of the Mhc-containing cosmids a gene which we designate Agph-DAB1.

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Platelet-derived growth factor B-chain expression in the rat retina and optic nerve: distribution and changes after transection of the optic nerve. Management of acute massive upper gastrointestinal hemorrhage: a panel discussion. Histological modifications of the skeleton of birds during moulting

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Candida albicans is an asexual fungus and as such must rely on mechanisms other than sexual recombination to generate genetic diversity. Gastrimmune immunisation may be a therapeutic option for the treatment of colorectal cancer in combination with 5-FU/leucovorin. A fusion of the sur-5 protein to the green fluorescent protein containing a nuclear localization signal is demonstrated as a marker for genetic mosaic analysis in the nematode Caenorhabditis elegans. These new cell lines are being used to study chemotherapy resistance in prostate cancer.

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Mutation analysis of 3a revealed that C-terminal region (176 aa approximately 274 aa), including a potential calcium ATPase motif, was essential for induction of cell cycle arrest. Intrinsic fluorescence emission from the cornea at low temperatures: evidence of mitochondrial signals and their differing redox states in epithelial and endothelial sides. The results of this field study provide insight in critical periods associated with reproduction in male and female Common hamsters. How synapses change their strength in response to impinging neural activity is a fundamental issue for understanding how the brain molds its circuitry in response to behavioral experience. Precision measurement of the orthopositronium vacuum decay rate using the gas technique.

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The activity of eIF2 is controlled by changes in phosphorylation of the alpha subunit of this factor. The occurrence of these enzymes some authors connect with the metabolism of sulphated polysaccharides (DOGSON 1968, MARTIN et al. To test the therapeutic potential of PEDF, we constructed a replication-defective adenoviral vector capable of efficient transduction and expression of PEDF (Ad-PEDF) in PC-3 prostate carcinoma cells. Immunochemical and functional characterization of an agonist-like monoclonal antibody against the M2 acetylcholine receptor.

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Risks concerned with being paid were recognised by all children. Here, we report the X-ray crystal structure of the oestrogen receptor alpha (ERalpha) bound to an oestradiol derivative with a prosthetic group, ortho- trifluoromethlyphenylvinyl, which binds in a novel extended pocket in the ligand-binding domain. These results emphasize the role of extracellular structures in determining mechanical function of smooth muscle. Transbilayer phosphatidylethanolamine (PtdEtn) movements in the plasma membrane of Saccharomyces cerevisiae are regulated by an ATP-dependent, protein-mediated process(es).

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Schizophrenia as a long-term outcome of pregnancy, delivery, and perinatal complications: a 28-year follow-up of the 1966 north Finland general population birth cohort. The present study was designed to explore systematically the midbrain of unanesthetized, decerebrate anuran amphibians (bullfrogs), using chemical and electrical stimulation and midbrain transections to identify sites capable of exciting and inhibiting breathing. Recently, large conductance ion channel activity (100-1000 pS) was recorded from the nuclear envelope (NE) of various preparations and it was suggested that NPCs may be the source of this activity. This pneumonia is only a small fraction of all hospital cases of chest infection and pneumonia.

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Clinical efficacy of Velac, a new tretinoin and clindamycin phosphate gel in acne vulgaris. Receptors for this cytokine are composed of two subunits, alpha and beta, and are expressed in myeloid progenitors and mature mononuclear phagocytes, monocytes, eosinophils and neutrophils, as well as in other non-haematopoietic cells. Detection of autoantibodies to desmoplakin in a patient with oral erythema multiforme. Sleep spindle activity was investigated in 120 healthy subjects aged 3 months to 16 years in 12 age groups.

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Toward independence of the mentally disabled and encouragement of their social participation--establishment of a basic law for their aid and user movements Properties of N-terminal tails in G-protein coupled receptors: a statistical ponstil forte para dolores menstruales study. Several clinical studies have validated the accuracy and reliability of high-resolution, fat-suppressed, three-dimensional, spoiled gradient-recalled MR imaging in the assessment of articular cartilage defects of the knee. This hydroxylation is a saturable process, that is, the rate of metabolism fails to increase in proportion to the serum concentration. Membrane lipid composition protects Entamoeba histolytica from self-destruction by its pore-forming toxins.

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In the present study, we have shown that cocaine is significantly more potent in suppressing the firing rate of dopamine cells in the ventral tegmental area (VTA or A10) than in the substantia nigra pars compacta (SNC or A9). Two independent reviewers applied the study selection criteria, assessed methodological quality and extracted data. Atrial natriuretic peptide induces acrosomal exocytosis of human spermatozoa. These results suggest that bonding efficiency of denture base resin to relining resins was affected by immersion condition, which caused potential degradation virestat aciclovir suspension of the denture base resin. Of the 162 coded cultures tested, 105 were identified by the exoantigen test as H.

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