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The results showed that PTG tissues from all three donors could retain their structure and secretory function for more than 100 days in the nude mice. Our results indicate a potential role of CD95L in oxidative stress-mediated cell death, ischemia/reperfusion and other diseases with a disturbed redox balance. These results demonstrate that recipient T-cells, pDC, and NK cells contribute to the host barrier for establishing chimerism, implicate deletional tolerance as the mechanism for total body irradiation-based nonmyeloablative conditioning for BM transplantation, and show a beneficial effect of BM cells in preventing sensitization to MHC alloantigens.

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Recent evidence suggests, however, that CD95 mediates not only apoptosis but also diverse nonapoptotic functions depending on the tissue and the conditions. 5T4 oncotrophoblast glycoprotein: janus molecule in life and a novel potential target against tumors.

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A better knowledge of the pathogenesis of type 1 diabetes (IDDM) may open the road to the prevention of the diseases. These results suggest that human PSTI may have a beneficial effect on acute pancreatitis. Granulocyte-macrophage colony-forming-unit assay and liquid suspension culture of bone marrow and peripheral blood in newly diagnosed childhood acute lymphoblastic leukemia. We have studied the expression of the Rho GTPases in adult rat brain with in situ hybridization and Western blot analysis. A novel colon pouch and its comparison with a straight coloanal and colon J-pouch--anal anastomosis: preliminary results in pigs.

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Microvascular density was higher in tumors with strong CXCL5 expression, but the correlation with CXCL5 was not linear. The diagnosis was established on the basis of the disease marker--tick-borne migrating erythema and serological data obtained with the use of indirect immunofluorescence and Western blot. A case of histiocytosis X complicated by recurrent spontaneous pneumothorax Both the high-energy pulsed CO2 laser and dermabrasion can achieve comparable clinical improvement in the revision of surgical scars. Among proteins of the same family, the sequences in regions involved in cofactor binding are strongly conserved.

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The selectivity of the two antagonists was proved by the findings that CAM-1028, but not CAM-1481, inhibited gastric acid secretion evoked by CCK-8 or gastrin-17 (CCKB receptor assay) while CAM-1481, but not CAM-1028, inhibited the CCK-8-induced contraction of guinea-pig isolated gall bladder strips (CCKA receptor assay). The MBGS tended to have higher CS, and may be less influenced by photograph quality and bleb type, suggesting that bleb photographs may be best encoded for statistical analysis in clinical studies using this system. This new monolithic stationary phase was prepared by the in situ polymerization of DMAEA with butyl methacrylate and ethylene dimethacrylate, using a ternary porogenic solvent consisting of water, 1-propanol and 1,4-butanediol.

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However, the mechanisms of somatic gene expression in testes are poorly understood. Evaluation of the safety and immunogenicity of a new, heat-treated human rabies immune globulin using a sham, post-exposure prophylaxis of rabies.

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Neonatal morbidity, multiplicity, low birth weight, prematurity, intrauterine growth retardation, transfer to intensive care, and length of hospital stay. A new method for measuring membrane potentials with external electrodes. Growth promotion by homocysteine but not by homocysteic acid: a role for excessive growth in homocystinuria or proliferation in hyperhomocysteinemia? The neuroprotective effects of VIP have been shown to be mediated via astroglial-derived molecules.

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The authors provide an overview of the stem cell engineering field, highlighting challenges and solutions, and focusing on recent developments in therapeutic applications in areas such as autoimmunity, CNS lesions, bone and joint diseases, cancer and myocardial infarction. Many antigenic variants, however, failed to cluster with their respective prototype strains, suggesting that this portion of VP2 may be inappropriate for consistent molecular inference of serotype and for detailed study of enterovirus evolution. Exposure of U251 cells and LN-Z308 cells to 0.5 mM SNP resulted in significant cytotoxicity over a 72-hour period. This study demonstrates for the first time a high frequency of antibodies to HSV-induced antigens confined to subjects at high risk of developing head and neck squamous carcinoma and in patients with these malignancies as well as a correlation between the levels of these antibodies and clinical course after treatment.

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Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Diurnal variations have a major influence on exposure levels at sites nominally exposed to the same regional ozone distribution.

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Histamine receptors are involved in the development of inflammatory pain and hyperalgesia, and the use of antihistamines is advocated as an alternative for pain therapy and treatment of postoperative nausea and vomiting. Kinetic studies of allosteric catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa.

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The findings suggest that neutrophils play important roles in the host defense against mycobacterial infection. We conclude that presence of the RPE is required for the normal development of the eye in vivo. Mapping the gene for sex-linked anemia: an inherited defect of intestinal iron absorption in the mouse. We report 3 cases of pulmonary Langerhans cell granulomatosis combined with either rib, thyroid or hypothalamus involvement. Interrelationship between the generation of oxygen anion-radicals and the reduction of artificial acceptors and cytochrome P-450 by NADPH-cytochrome c reductase

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Viruses that agglutinate, or do not agglutinate, chicken red cells show identical binding to a Glycan Array of 264 oligosaccharides, binding exclusively to a subset of alpha2-6-sialylsaccharides. It is suggested that neurogenic myocardial damage is accompanied by discoordination in the energy processes regulation with uncoupling of the oxidative phosphorylation and by a decrease of the macroergic compounds synthesis. Synthesis of 1-ethyl-, 1-n-dodecyl-2-phenyl-3-(n-alkylthiomethyl)- and 1-ethyl-, 1-n-dodecyl-2-phenyl-3-(n-alkoxymethyl)imidazolium chlorides A biopsy specimen 30 months after Q-switched ruby laser therapy revealed a lentigo maligna melanoma.

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Improved methods for prevention of mother-to-child transmission of hepatitis B virus In contrast, the effect of QTL on serum total cholesterol on chromosome 4 (Npy-Spr) was maximal at 32 weeks of age. Collagenolytic activity of rabbit V2-carcinoma growing at multiple sites. Energy relaxation time between macroscopic quantum levels in a superconducting persistent-current qubit.

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Leukemia cell differentiation: cellular and molecular interactions of retinoids and vitamin D. During successive stages of development, new groups of ANF-immunoreactive cell bodies appeared. Effect of ACTH and hydrocortisone on the functional state and interaction of brain structures

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The chronic inflammatory response is an intermediary between the acute inflammatory process and glandular atrophy. In malignant insulinomas, besides a strong immunoreaction for c-myc and TGF alpha, activation of c-K-ras and overexpression of p53 protein were found.

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Throughout the SCN, particularly in its ventral portion, GFAP-like-immunoreactive (GFAP-LI) astroglial elements were found. FIV-PPR is able to productively infect feline peripheral blood leukocytes (PBLs) and a T lymphocyte cell line (MCH5-4), but not a feline astrocyte cell line (G355-5) or Crandell feline kidney cells (CrFK). Overexpression of cystatin alpha resulted in an increase of the amount of cyclin B, suggesting that cysteine proteinase cathepsins might be involved in the degradation of cyclin B.

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Peritoneal implantation of meningeal melanosis via ventriculoperitoneal shunt: a case report and review of the literature. exigua (Se301) cells to the Bombyx mori nucleopolyhedrovirus (BmNPV). Effects of endogenously activated transforming growth factor-beta on growth and differentiation of retinoic acid-treated HL-60 cells. IL6, aspirin, nonsteroidal anti-inflammatory drugs, and breast cancer risk in women living in the southwestern United States. Relationship between end-tidal and arterial carbon dioxide with laryngeal mask airways and endotracheal tubes in children.

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Compared to these new techniques, IRA had a lower incidence of postoperative fecal incontinence, and was one-stepped in the majority of the patients. Medical records and smears of bone marrow aspirates were reviewed to determine clinical features, laboratory test results, treatment, and outcome of this syndrome in cats. To improve the understanding of forelimb-hindlimb balance and its underlying temporal changes in relation to different head and neck positions.

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However, in metabolic labeling experiments with 14C-labeled mixed amino acids, a consistent decrease also was demonstrated in the biosynthesis of the same protein in the SV40 virus infected subclone, as compared to an uninfected sister subclone, during exponential growth. However, in ciliates a high degree of variation was found compared both to other eukaryotes and between the ciliate species. RT-PCR using primers specific for each of the 11 Sprr2 members demonstrated varying degrees of expression among the individual Sprr2 members in different tissues. A common property of allergens is their potential to generate type 2 cytokine responses.

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TTM injected into rats or incubated in vitro with serum does not remove Cu from ceruloplasmin. Changes in plasma endothelin-1 levels reflect clinical response to beta-blockade in chronic heart failure. In the direction of phosphorylation of fructose-6-phosphate (F6P), initial velocity double-reciprocal plots for both PPi and F6P were intersecting suggesting sequential addition of substrates. The purpose of this study was to characterize anisotropy in the triangle of Koch by relating electrophysiology with anatomy.

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The prevalence of vascular disease among 154 diabetic patients was analysed in relation to the serum concentrations of individual lipoproteins. This article includes a description of the method of dermabrasion and a discussion of the results obtained in various types of dermatologic conditions. The histology of lymph nodes disclosed inflammatory necrotizing granulomas, but acid-fast stain for M. Methanogenesis completely recovered in the dextrin/peptone-, glucose-, and acetate-fed cultures at all nitrate levels. Light microscopic immunocytochemistry indicated that the MCT2 transporter was abundant in glial limiting membranes, ependymocytes, and neuropil, particularly in the lacunosum molecular layer of hippocampus and the molecular layer of cerebellum.

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We previously demonstrated that mammalian sperm nuclei contain a nuclear matrix that organizes the DNA into loop domains in a manner similar to that of somatic cells. We have found in our Canary population an association between Alzheimer disease with exonic variants of ApoE gen with a strong modulation by the patients gender.

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In these biomes, the saprotrophic wood-decay fungi are the only organisms that can completely decompose woody plant litter. The simultaneous determination of ketamine and midazolam using high pressure liquid chromatography and UV detection (HPLC/UV) Efforts to achieve further decreases should focus on reducing risky behavior, promoting the use of effective contraceptive methods and improving the effectiveness with which all methods are used. Twenty-five of the exons of the two genes are almost identical in size, six of them contain conserved split codons, and the locations of the respective exon-intron junctions are identical or almost identical in the two genes.

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True community-acquired methicillin-resistant Staphylococcus aureus bacteremia. 5-fluorouracil (5-FU), thiotepa, methofrexate were repeatedly injected into the pelvic retroperitoneal space of 25 dogs and 24 patients respectively via cannulation.

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A simple assessment of peritoneal transport in stable continuous ambulatory peritoneal dialysis patients. SURGICAL IMPORTANCE OF A DERMOCARTILAGINOUS LIGAMENT IN BULBOUS NOSES. Ureterovaginal fistulas: treatment with preservation of the distal ureteral segment.

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Eighty-three hospitalized psychiatric adult patients were examined for the primary form of CVG. This interaction can initiate nitration and hydroxylation of aromatic molecules such as tyrosine residues and may thereby contribute to the biochemical and toxic effects of the molecules. These findings may have implications for the effect of these compounds on LDL in vivo. Purification of DNA complementary to the env gene of avian sarcoma virus and analysis of relationships among the env genes of avian leukosis-sarcoma viruses.

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Atom probe specimen preparation with a dual beam SEM/FIB miller. The diagnosis was made postmortem, based on histopathological findings. This study was designed to determine whether melatonin alters the release TNF, IL-6, and reactive oxygen intermediates by activated macrophages.

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Furthermore, the low transcriptional and translation responses of the MT gene to Cd stimuli in WF rats might explain the higher susceptibility of this rat strain to develop malignant lung tumors after chronic exposure to Cd via inhalation. To clarify the physiological significance of myosin isoform redistribution in cardiac adaptation process, we compared the kinetic property of the two cardiac myosin isoforms using in vitro motility assay techniques. All the articles from 1972 to 2005 that discussed a specific surgical therapy in BPPV were reviewed.

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The activation of JNK elevates the level of IRS-1 phospho-serine 307 and might play a role in insulin resistance after burn in rats. The possible relationship between the persistence of chromosomal aberrations and the development of malignancies are discussed in this paper. Nuclear modification in ovocytes in sturgeon during transformation to the spawning state following pituitary injection

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Several lines of evidence indicate that cholinergic basalis neurons play an important role in cortical activation. Generally, compounds discriminated by animals possess psychotropic effects in animals and humans. Thirteen derivatives of 6,7-methylenedioxy-1 (2H, 4H)-acridone were prepared. A new enzyme has been characterized in a cell-free extract of Bifidobacterium bifidum that catalysed the reversible phosphorolytic cleavage of beta-1,3-galacto-oligosaccharides. Time evolution of a charged oscillator with a time-dependent mass and frequency in a time-dependent electromagnetic field.

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The present experiment examines the relationship between SCN neuronal activity and the expression of overt circadian behavior in the Djungarian hamster (Phodopus sungorus). The results are discussed in terms of the significance of sexuality for general well-being during adolescence. These cells were seen on electron-microscopic study to have Langerhans granules in the cytoplasm, which led to a diagnosis of Langerhans-cell histiocytosis concomitant with multiple myeloma. Sensibility testing in patients with a lumbosacral radicular syndrome. The application of a digital whole body scanner to the dosimetry of intralymphatic 32P/131I Lipiodol.