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Invasive Aspergillosis in patients with acute leukemia: update on morbidity and mortality--SEIFEM-C Report. Characterization of sulphate transporters in isolated bovine articular chondrocytes. The method is examined by linearity and precision tests and is applicable to biological sample matrices like cell supernatants of human basophils enriched by Percoll-density gradient centrifugation and stimulated for mediator release by anti-IgE.

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Here we demonstrate that DNA ligase I and the large subunit of replication factor C (RF-C p140) have a homologous sequence of approximately 20 amino acids at their N-termini that functions as a replication factory targeting sequence (RFTS). They have also attempted to integrate the basic knowledge of Western medicine into the study and practice of Thai traditional medicine. The diagnosis is based on a visual investigation of CT images, which is a time-consuming and subjective procedure. (2) Real-time qRT-PCR was performed to detect the mRNA expression of VEGF-C and -D genes in 67 cases of primary breast infiltrating ductal carcinoma. In October 2003, a package containing ricin and a note threatening to poison water supplies was discovered in a South Carolina postal facility, becoming the first potential chemical terrorism event involving ricin in the United States.

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To evaluate the effects of aripiprazole for people with schizophrenia and schizophrenia-like psychoses. A point prevalence of CMV excretion in family homes was determined by sampling 106 children from 25 randomly selected homes. Liver tumors occurred in males of CBA strain 7-fold more frequently than in females.

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Report on the 2002 Pediatric Orthopaedic Society of North America Traveling Fellowship. In their totality, 5-LO products of arachidonic acid contribute to the impairment of the normal glomerular filtration and sieving functions that attend acute inflammatory injury in the renal glomerulus and to the subsequent progression of glomerular destruction. Asia 1 causes the second largest number of disease outbreaks in India.

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Infection in the stomal and/or main wound and subsequent complications were prevented. Linear regression analysis was performed on data from each of the 3 intervals as well as for pooled data from all 3 periods.

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Anomalies of the carotid artery are rare in clinical experience. Our results support no role for these antigens in immune complications of ASCT: PLT engraftment, requirement of PLT transfusions, and GVHD. The purpose of this study was to evaluate the utility of posttreatment total body iodine-131 (I-131) scans. Agreement between premortem and postmortem diagnoses in patients with acquired immunodeficiency syndrome observed at a Brazilian teaching hospital.

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Role of carbon fibre implants in osteochondral defects of the knee. Production of chemoattractant from cultured rabbit cervical explants at term pregnancy was also higher than that from nonpregnant explants. Biomechanical evaluation of intramedullary nail versus tension band fixation for transverse olecranon fractures. In some cases, small but significant differences were noted between the theoretical and observed molecular masses, suggesting that there exist still unknown modifications.

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Our study also reveals that the lambda-based screening system is a robust new tool for the genetic analysis of highly toxic recombinant products in E. Early development candidates are often selected for pre-clinical and clinical development based primarily on pharmacological and toxicological data. Reference lists were checked and we contacted experts in the field to identify further published and unpublished studies.

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This type of coping can also be used after a period of soft tissue healing when a healing abutment is employed. Six of the nine patients developed delayed traumatic intracerebral haematoma, two epidural haematoma and one subdural haematoma. Self-consistent kinetic calculations of helium rf glow discharges. Light scattering near a double critical point: Evidence for crossover behavior. We have recently demonstrated that NF-kappaB activation mediates the repression of autophagy in response to TNFa in three models of cancer cell lines.

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Comparison of the equilibrium constant in a zinc chlorin with those of the corresponding zinc bacteriochlorin (7,8-dihydrochlorin) and porphyrin (17,18-dedihydrochlorin) led to an increase in the saturation and flexibility of the tetrapyrrole pi-plane ligands making the central zinc more axial-ligated. Evidence for scaling in an interfacial growth instability: The solid case. During the first two weeks after release, prisoners in Washington State had 129 times the death rate from drug overdose, compared to other state residents--probably because they did not know how much less drug they could tolerate, after taking little or none of it in prison. Cerebral ischemia was induced, using the bilateral carotid artery occlusion method, for 60 min followed by reperfusion up to 120 min in gerbils.

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Autoaggregation was frequently encountered among intestinal lactobacilli isolated from weaned pigs. We have derived a novel approach to the derivation of these matrices that utilizes not only multiple sequence alignments, but also the associated evolutionary trees. Since the rotational behavior is induced on the basis of asymmetry of the basal ganglia output activity, there must be a marked difference between the GP ablation and the administration of D2 receptor blockade on the basal ganglia output activity, supporting a speculation that overactivity of the basal ganglia under dopamine depletion is not solely a result of the disinhibition from the inhibitory GP efferents. The purpose of the study was to assess the accuracy of a group of strabismologists applying the Hirschberg and Krimsky tests. Climate change and the marine ecosystem of the western Antarctic Peninsula.

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Histological studies showed a massive depletion of thymic cortex. These results suggest that the nature of the self-aspect from which persons recall their experiences determines whether mood-congruent or mood-incongruent recall occurs. Two unusual cases and further evidence that VIP is a humoral mediator. Adult sarcomas: a missed opportunity for sustained cooperative group translational and clinical research.

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Estrogen receptors (ER) have been mapped in the brainstem of the female sheep with immunocytochemistry. Eighty enterococci strains isolated from blood cultures, since 1989 to 1993 were studied.

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Isolation of the first crystalline D-penicillamine complex of iron and some remarks on relevant aspects of metal-chelating drugs as well as metabolism disorders. It has been proposed, on the basis of animal experiments, that medium-chain triglycerides (MCT) may exert more favorable effects on whole body metabolism of injured animals than long-chain triglycerides (LCT). pyriformis phagocytosed some Pseudomonas pigment-forming species (P. We consider cosmic microwave background (CMB) anisotropy in models with quintessence, taking into account isocurvature fluctuation.

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For the first time, FKBP51 expression, in particular gene expression and subcellular localization was described in bone marrow cells of non-neoplastic and neoplastic haematopoiesis grown in vivo. The incidence data in 1973-2002 were age standardized to the 2000 USA standard population and analyzed by the joinpoint regression. No association was found between the P1A2 polymorphism of GpIIIa and young women with stroke.

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Neurophysiological concepts as they pertain to muscles and motor control principles are reviewed. To investigate a possible mechanism for this hypomethylation, levels of hepatic metabolites and enzyme mRNAs involved in one-carbon metabolism were measured using HPLC with coulometric electrochemical detection and real-time RT-PCR, respectively. In addition to other expressing tissues, Ex-FABP, CAL beta and CAL gamma genes are highly transcribed in chondrocytes at late stages of chondrogenesis during endochondral bone formation and/or upon inflammatory stimulation. Alignments of the protein sequence of the dimeric thermophilic glycyl-tRNA synthetase (Gly-tRNA synthetase) derived from its gene with sequences of other dimeric Gly-tRNA synthetases revealed an atypical character of motif 1 in all these class 2 synthetases.

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Assessment of infant brain development with frequency-domain near-infrared spectroscopy. A dominant, gain-of-function mutant allele of PDR13 was isolated and shown to have the same phenotypic effects as when the gene is present on a 2microm plasmid. A highly efficient ruthenium-catalyzed rearrangement of alpha,beta-epoxyketones to 1,2-diketones.

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Here we show that loss of erbB signaling leads to changes in OL number and morphology, reduced myelin thickness, and slower conduction velocity in CNS axons. Regulation of arginase isoforms I and II by IL-4 in cultured murine peritoneal macrophages. Data from the 1999-2000 Bangladesh Demographic and Health Survey and from the Matlab Demographic Surveillance System area collected between 1978 and 2001 were analyzed to explain the lack of change in fertility and to examine relationships among contraceptive prevalence, the abortion ratio, desired fertility and total fertility. Once IE is suspected, further testing with blood cultures and echocardiography can confirm the diagnosis and lead to early treatment with bactericidal antibiotics and surgery when appropriate, thus reducing the morbidity and mortality of IE. Preventative measures, such as circuit charge dissipation, may reduce the potential for such damage when using PVC tubing.

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Administration of electrolyte paste is advantageous over water alone in restoring fluid, electrolyte, and acid base balance after fluid and electrolyte loss attributable to furosemide administration. MTT was used to test the toxicity of the two components of catechin. Caspases are activated during apoptosis and cleave specific proteins, resulting in the irreversible commitment to cell death. The second case occurred in a female aged 29, suffering from trichophytosis on her left arm. The transmission dynamics and morbidity associated with the major helminth infections (Ascaris lumbricoides, Trichuris trichiura and the hookworms) are dependent on the size of the worm burdens.

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Alterations in TSH-receptor in two transplantable rat thyroid tumors. 2-CdA is an active agent for patients with previously treated, advanced, indolent NHL and may result in lasting remissions. In normal skin, p16 and p21 were not detectable but significant expression of these proteins was detected in tumors. To compare the efficacy, safety, and tolerance of enalapril and nifedipine in hypertensive patients with non-insulin dependent diabetes. All substrates showed extensive neovascular and fibrous tissue ingrowth within 2-weeks post-transplantation.

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Additionally, growth of the mutant cells in the presence of this antiserum causes a reversal of the virus-resistant phenotype. Depressed mood and dietary fish intake: direct relationship or indirect relationship as a result of diet and lifestyle? Presence of sensorineural hearing loss as assessed by brainstem auditory evoked response. The peak of ornithine decarboxylase activity as a marker of G1 phase was at 10 hr, and subsequently the labeling index of proliferating cell nuclear antigen as a marker of S phase increased at 53 hr. The BiFC assay is based on the discoveries that two non-fluorescent fragments of a fluorescent protein can form a fluorescent complex and that the association of the fragments can be facilitated when they are fused to two proteins that interact with each other.

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Clinicians can adopt a number of different strategies to overcome the many barriers associated with routine delirium assessment in the ICU. Intraocular pressure, inflammation, clarity of the visual axis, visual acuity, refraction, complications, and retention of the prosthesis. Binding interactions of a new series of anthrapyrazoles (APs) with DNA were evaluated by electrospray ionization mass spectrometry (ESI-MS). The MCM LS C-terminal region also exhibits homology to other enzymes that have cobalamin-containing cofactors. Prognosis in cases of erythrocyte immunisation has improved continuously over the past decades.

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This was due to a greater amount of anticoagulant in the bag samples. No place like home: a history of nursing and home care in the U.S.

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Significant pulmonary regurgitation (PR) could result in right ventricular (RV) dysfunction, exercise intolerance, arrhythmia, and sudden death. In the diagnostics of intracardiac tumors transthoracic and transesophageal echocardiography provide the methods of choice to visualize quickly and noninvasively the extent, mobility, and origin of the tumor.

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The evolution of mammary cancer induced in virgin female IF mice with minimal doses of locally-acting methylcholanthrene. By what means does the rheumatic patient with gastrointestinal risks fare best?

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Practical problems must be discussed before such a vision can be further developed. To assess the effects of the interactions on free-running circadian rhythmicity, body temperature was measured by means of radio telemetry. Erythrocyte protoporphyrin concentrations in clinically normal cats and cats with lead toxicity. In general, however, CYP1A and CYP3A levels and related enzyme activities are usually reduced and CYP2C, CYP2A, and CYP2B are mostly unaltered.

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Several SA-responsive genes are regulated by basic/leucine zipper-type transcription factors of the TGA family. Rhinorrhea after neurotologic surgery may be indicative of a cerebrospinal fluid (CSF) leak or may be secondary to autonomic dysfunction as a result of injury to preganglionic parasympathetic fibers. These results suggest how heterochromatin proteins might be recruited to specific sites on DNA with resultant specific effects on gene expression.

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Epithelial cells in vivo form tight cell-cell associations that spatially separate distinct apical and basolateral domains. The tumor suppressor protein p53 and the adenoviral 12 S E1A oncoprotein are both known to elicit their biological effects mainly by regulating the transcription of important cellular genes. Rice UDP-glucose pyrophosphorylase1 is essential for pollen callose deposition and its cosuppression results in a new type of thermosensitive genic male sterility. Two basolateral sorting signals have been mapped to the cytoplasmic juxtamembrane region of the receptor, a dominant signal comprised of a polyproline core (667-PXXP) and a preceding basic residue (Arg662), and a consensus leucine-based signal (658-LL) responsible for residual sorting when the 667-PXXP signal is absent or defective. coli K88ab fimbriae to guinea pig erythrocyte membranes, as a possible model of the target host cell were studied.

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ET immunoreactivity was not related to duration of implant use or total number of bleeding days. The rate of yeast and mould colonization and the species of fungal isolates were essentially the same for both groups of patients. Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products. However, for a treatment to be effective in a wide-ranging manner, improvement in various life domains, such as social functioning, independent living, and employment, should also be found.

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Myths of isotretinoin therapy in patients with acne: a personal opinion. A 14:3:3 protein binding site was identified in the mature region of the (35)S-pPORA, which governed 14:3:3 protein- and Hsp70-mediated, Pchlide-independent plastid import. Epigenetic regulation of gene expression is implemented by a wide repertoire of histone and DNA modifying enzymes including the acetyltransferases and deacetylases, the methyltransferases and kinases among others.

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These data suggest that the proenkephalin transcript found in abundance in rat heart is the same form as found in the brain, and differs from the testis-type transcript. Although similar calculations have not been made for HBV-associated HCCs, it is likely that this is also the case for HCCs, since individuals with persistent HBV infection do not usually develop HCC until they are 45 or greater years old.

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Published data on the binding protein-dependent transport of histidine in membrane vesicles of Salmonella typhimurium were also used. The sensitivity of the cell cultures is certainly equal if not superior to that of the tongue of bovines. We describe a patient who developed acute colonic ischemia following ethylene glycol intoxication. Nicotinic acetylcholine receptors of the central nervous system of Drosophila. They completed self-report recovery and other mental health measures and their case workers completed the Health of the Nation Outcome Scales.

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In 35 patients, a circular stoma was created and in one a V flap was used. There is experimental evidence for a claim that the antioxidant functions of vitamins (E, C, and beta-carotene) may prevent restenosis post-PTCA. Two-dimensional analysis of hemodynamic changes in axial and random pattern flaps.

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In this short address, I explore the qualities that Franklin possessed in the medical realm. Serological evidence is presented for the existence of JC virus as a distinct entity before the use of simian virus 40-contaminated poliovirus vaccines and for the nonexistence of an animal reservoir for JC virus infection. Extending the hydrophobic domain of the short, cleaved Ncyt/Cexo signal of pre-provasopressin-neurophysin II and shortening that of the Nexo/Ccyt signal anchor of microsomal epoxide hydrolase resulted in a significant fraction of polypeptides inserting in the opposite orientation to that of the wild-type proteins.

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Our results suggest that cells expressing higher levels of PrP(C) have higher resistance to oxidative stress or copper toxicity but are more sensitive to PrP106-126 toxicity. Suminoe oysters, of the non-indigenous species Crassostrea rivularis (Gould), were introduced into France to test their ability to adapt to local conditions. Major complications of operative gynecologic laparoscopy in southern Taiwan: a follow-up study.

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This study documents the importance of genetic factors in a proportion of FTD patients with the age at onset of dementia in first-degree relatives being 11 years earlier than in the general population. Protein content was the most sensitive macromolecule affected by effluent. The model predicts the optimal monophasic duration and the first phase of a biphasic waveform to within 1 msec as tau s varies from 1.5 to 6 msec: for tau s equal to 1.5 msec, the optimal monophasic waveform duration and the optimal first phase of a biphasic waveform is 2 msec, for tau s equal to 3.0 msec, the optimal duration is 3 msec, and for tau s equal to 6 msec, the optimal duration is 4 msec. PatchXpress, an automated 16-channel parallel patch clamp system, was used to determine inhibition of human ether-a-go-go related gene (hERG) potassium channels by known blockers.

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These include four proline residues located in or near loop regions, and one alanine and one arginine located at helix regions in the predicted TaqI endonuclease secondary structure. After a single injection clozapine significantly suppressed REM sleep in a dose-related way, leaving slow wave sleep (SWS) unchanged.

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The termination defects of a few mutant RNAPs could be attributed to altered interactions with the NusA protein, but rho-dependent termination by most of the defective RNAPs was still stimulated normally by NusA. This assay assesses somatic recombination and mutational events. Achievement of such results would be possible, if the State Sickness Fund and the Ministry of Health would pay more attention to financial problems of interventional cardiology in Lithuania. Our results indicate that vasoconstricting prostanoids are released from the endothelium of the human umbilical vein at hyperoxia. To determine the fate of the atrioventricular endocardial cushions in cardiac development, we used staining methods for extracellular fibronectin, which is abundant in the endocardial cushions, and actin, which is abundant in the myocytes.

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Stress and anxiety evoke a similar physiological response to acute pain, highlighting the need for efficient cognitive management programmes. However, synergistic activation of the ZTA promoter was not observed when ZTA and C/EBPalpha were cotransfected together in either HeLa or DG75 cells.

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Some medico-legal problems confronting medico-legal examiners and general medical practitioners. In addition, we show that Mala s 1 binds to the phosphoinositides (PI) PI(3)P, PI(4)P, and PI(5)P, lipids possibly playing a role in the localization of Mala s 1 to the cell surface. It is also beneficial in studying the possible mechanisms and genes implicated in normal morphogenesis of cardiac chambers, septa and valves. Then, STM images were obtained in which the STM was operated in air at atmospheric pressure with a tip-to-substrate bias voltage of 250-1000 mV (sample positive) and the tunneling currents in the range of 10-20 pA by using etched tips of Pt/Ir, in constant current mode.

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The structure of lipid layers on the surface of aerosil is discussed. Randomized trials between behenoyl cytarabine and cytarabine in combination induction and consolidation therapy, and with or without ubenimex after maintenance/intensification therapy in adult acute myeloid leukemia. The in vitro and in vivo results were in good agreement in showing that GnRH-III is only a weak agonist of the endocrine activity of GnRH. Three nursing units characterized as at high risk had a pneumonia rate of 1.90 per 1000 patient days, as compared with a rate of 0.70 cases per 1000 patient days on the two other units.