Hipokinon comes as a tablet and elixir (liquid) to take by mouth. It usually is taken with or without food three or four times a day. Take Hipokinon at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Hipokinon exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Do not stop taking Hipokinon suddenly without talking with your doctor, especially if you are also taking other medications. Sudden stoppage can cause symptoms of Parkinson's disease to return.

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CHALN metastases correlate with poor prognosis and no long-term survival. Hand eczema in a prospectively-followed cohort of office-workers. bovis, while in groups exposed to lower doses, the time until antibody was detected increased as the challenge dose decreased.

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Four cases are reported and, using MEDLINE, the English and non-English literature from 1982 to 2002 is reviewed. Variability in heart rate was compared between 5 min of spontaneous and controlled breathing. Our clinical experience of some 300 adolescents with obesity between 9 and 18 years of age and their parents has convinced us that consideration of parenting styles is fundamental in the treatment of children and adolescents with obesity.

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Zinc is an essential trace element for many biological functions, including immune functions. Subjects were subdivided into 3 groups: 15 subjects Helicobacter pylori positive CagA-positive, 15 Helicobacter pylori positive CagA-negative and 15 controls Helicobacter pylori negative. The process of adaptation to the conditions of sleep in the laboratory during the 2nd and 3rd night was studied.

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In addition, our results show that treatment with Co-nano somehow activates cellular pathways of defense and repair mechanisms. Characterisation of secondary spermatocytes in the marbled newt (Triturus marmoratus). However, as the models become more specific, some sequences found by Pfam may be missed by the models in FPfam and some of the families represented in the test set are not present in FPfam. Intermediate myasthenia syndrome following acute organophosphates poisoning--an analysis of 21 cases.

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As rescue therapy plasmapheresis and added immunosuppression were often successful. Repetitive, low-dose tissue plasminogen activator for clearance of experimental vitreous hemorrhage. The effect of provocation on left ventricular (LV) outflow was studied by continuous-wave Doppler echocardiography in 103 nonselected, consecutively enrolled patients with LV hypertrophy (LVH), either due to pressure overload (97 patients) or hypertrophic cardiomyopathy (HCM, 6 patients). The brain hypothalamus coordinates extra-hypothalamic regions to maintain energy homeostasis through the regulation of food intake and energy expenditure.

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In thymic rudiments of all specimens examined, virus particles were seen in epithelial cytoplasm, budding from epithelial cell surfaces and in extracellular spaces. Redox state of the electron-transport carriers in cardiac mitochondria: a study by the method of low-temperature EPR spectroscopy

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The data enable the anisotropy of electrical polarisability deltaalpha to be determined. The need for a rapid separation in the second column is overcome by repeating analysis of a sample many times. The relationship of this finding to our earlier report of a deficit of DBH in post-mortem brains of schizophrenics is discussed.

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Among 699 isolates retrieved from those specimens evaluated, 5 from 25 HIV-seropositive patients and 1 isolate from a patient whose HIV status was unknown were shown to be consistent by phenotyping and by electrophoretic karyotyping with the European reference strain of C. E1AF transcription factor, a member of Ets family, is deregulated in many tumors and widely known to play critical roles in tumor metastasis via directly binding to the promoter of genes involved in tumor migration and invasion. Integral-equation approach to the surface structure of classical insulating liquids. A monoclonal anti-idiotypic antibody which was induced against carboxypeptidase A (CPA) showed the catalytic activity similar to the original antigen. Despite the growing interest in depression being managed as a chronic illness, this review identified only 17 observational studies of depression in primary care, most of which have included small sample sizes and been relatively short-term.

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Aberrant mucin receptor expression can contribute to increased cell growth and metastatic ability. In particular, the changes underlying monoclonal growth in the parathyroids of patients with II degree HPTH are not well understood.

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Effect of substitution of monovalent anions in external medium on the swimming pattern of Salmonella typhimurium. Improvement in exercise capacity was greatest in patients with the poorest preoperative exercise capacity and in men. The activity of some intracellular oxidative enzymes in the thyroid follicular epithelium of Xenopus laevis Daud. Furthermore, Id-1 enhanced nuclear translocation and the transcriptional activity of HIF-1alpha.

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Primary iliopsoas abscess successfully treated by ultrasonographically guided percutaneous drainage. To compare three methods of segmental lower colon resection for treatment of symptomatic intestinal endometriosis. A comprehensive surveillance system for occupational injuries to adolescents does not exist in Texas, as in most states. In our opinion, a combination of laparoscopic-guided needle biopsy and laparoscopic excisional biopsy is more reliable than simple biopsy alone for the diagnosis of cirrhosis in children with chronic liver disease. Magnocellular AVP neurons are initially stimulated while parvocellular CRH and AVP neurons are stimulated throughout the experiment.

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Airflow standardised lung sound intensity does not differ between normal and emphysematous subjects. (18)F-FDG small-animal PET mouse xenograft studies were reproducible with moderately low variability. The effect of iodine on lipid peroxidation and ultrastructure in the thyroids of BB/Wor rats. Recent contributions of radiology to the diagnosis of subacute and chronic gastritis

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Recent research in total hip arthroplasty has focused on attempts to decrease wear at the femoral head-acetabulum articulation, to limit the production of debris that is believed to lead to osteolysis and prosthetic loosening. The difference in growth rate (delta mu) between plasmid-free and plasmid-containing cells and the rate of plasmid segregation (R) were determined using a non-linear regression technique. Hydrostatic issues have been addressed by making pressure recordings at the level of the symphysis pubis.

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A high index of suspicion coupled with radiographic imaging is essential to make a timely diagnosis and guide therapeutic intervention. C-type natriuretic peptide in individuals with normal left ventricular systolic function. This article reports a case of a man with a mutation in the desmin gene suffering from cardiomyopathy and skeletal myopathy. Prognostic significance of albuminuria for the development of nephropathy.

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Respiratory mechanics during exercise in endurance-trained men and women. Toxic effects that are usually observed result from continued use of large dosages or withdrawal of therapy. All active treatments were significantly more effective than placebo in relieving nasal symptoms at each treatment week. Metastable states are identified which are associated with a narrow size distribution and a coverage dependent mean island size.

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Dorsal pancreatic rudiments were dissected on E13.5, separated from surrounding mesenchyme and cultured for 7 days without or with recombinant IGF2. Establishing a role for sphingolipids in renal injury and stress responses. The lower PPF to N-vinyl pyrrolidinone ratio samples gained a maximum compressive strength of 7.5 MPa initially and a compressive modulus of 134.0 MPa at 1 week. After pretreatment of mice daily with ginseng extract (GE) for 5 days, concomitant injections of MAP and GE suppressed the development of reverse tolerance to the effect of MAP, although GE itself did not affect the spontaneous motor activity of the naive mice.

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Size homoplasy in chloroplast microsatellites of wild perennial relatives of soybean (Glycine subgenus Glycine) The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are two widely used laboratory markers of inflammation.

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Clinical and pathological differences between mature and immature teratomas Quantum dynamics, metastable states, and contractive semigroups.

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Integration host factor is a sequence-specific, histone-like, multifunctional DNA-binding and -bending protein of Escherichia coli. This has important implications regarding the empiric treatment of lymphadenitis in children. Channels used by recreationists to gain information about water quality, the perception of water quality and resulting behaviour were investigated. Percutaneous absorption of methylprednisolone aceponate after single and multiple dermal application as ointment in male volunteers. Time to expand our horizons regarding real-life studies of self-management and psychosocial outcomes.

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At 8 weeks, in the spinal cord, white matter changes in cervical segments 1 and 2 consisted of prominent multifocal axonal swelling in the fasciculus gracilis nerve tracts. The production of anti-citrullinated peptide antibodies is closely associated with the presence of the HLA-DRB1 shared epitope, a known risk factor for development of RA, and the production may be influenced by environmental factors such as tobacco smoking.

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Variance of transmitted power in multichannel dissipative ergodic structures invariant under time reversal. In a single patient without hyperparathyroidism, a precipitous decrease in serum calcium was observed due to clodronate.

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We have already reported that TE-5 improved the reduction of trace element concentrations induced by TPN. As isolated plasmacytoma of the conjunctiva seems to be benign, treatment of such tumours should be conservative.

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Brain-derived neurotrophic factor (BDNF), Neuritin and Activity-regulated cytoskeleton-associated protein (Arc) belong to a subgroup of immediate early genes implicated in synaptic plasticity known as effector immediate early genes. In addition, five peptides spanning different lengths of the arginine-rich domain, each containing the tryptophan residue, and two C-terminal deletion mutants of Rev, Rev M9 delta 14 and Rev M11 delta 14, were examined. The PRECEDE-PROCEED model: application to planning a child pedestrian injury prevention program.

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Factors which may potentiate radiation retinopathy should be well known including, increased radiation dosage, increased fraction size, concomitant systemic vascular disease and use of chemotherapy. In the other hand, PMC were grown on T-75 flasks and microcarrier beads to investigate endothelin-1, nitric oxide and prostaglandin pathways in vitro. Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells. Anatomy and ethics: an exploration of some ethical dimensions of contemporary anatomy.

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Probability tables were constructed from the results of the present study. For some radionuclides, notably 239,240Pu, 241Am and 99Tc, the work has added significantly to the data that are presently available.

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Escherichia coli 781-55 and E2987-73 are the type strains for H44 and H55 antigens, respectively. The resulting model has a rich behaviour including multiple stable states and oscillations. Transurethral cystometry was a feasible examination technique in pigs.

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Secreted protein acidic and rich in cysteine (SPARC) is highly expressed in human gliomas and promotes glioma invasion. Histological sections were prepared and stained with hematoxylin and eosin or for tartrate-resistant acid phosphatase (TRAP) activity.

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Air conditions were similar but soil temperatures differed by treatments (9, 13, 18 and 21 degrees C) during the second growing period in the dasotrons. Promoter II and I.3 activities in breast cancer tissue, however, are strikingly increased. This study investigated the possibility that lateral judgments made by inexperienced listeners who did not receive feedback might be different than those reported for experienced listeners, especially when the ITD is longer than that occurring in nature, and therefore data from inexperienced listeners presented unnaturally long ITDs for the first time might be more consistent with the possible interpretation of the fMRI results. To describe the importance of a professional code of ethics and values in guiding and supporting the practice of nurses and to present the proposed Oncology Nursing Society (ONS) Statement of Core Values. Site-directed mutagenesis of either site lowers the reporter gene activity by tenfold to a basal level.

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On the basis of this new knowledge, the development of novel therapeutic strategies to circumvent this clinical side-effect of cancer treatment has already begun. An ex vivo synovial tissue culture system was established to investigate the functional properties of CRH at peripheral sites of inflammation. Treatment with monoclonal antibodies against GM-CSF abrogated tumor regression in GKO but not in BALB/c mice.

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Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB. Generalized multistructural calculation of the optical and generalized oscillator strengths for inner-shell excitations in N2. No elevations of 17 beta-estradiol serum levels were recorded at the lower dosages, whereas the increases of estrone serum levels were approximately tenfold over basal levels. Calcitonin was used to confirm its inhibitory activity of bone resorption in this model.

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This involved identifying eligible RCTs and extracting aggregate data from the abstracts or reports of these RCTs. In a retrospective review of 51 patients with benign obstruction of the hepatic IVC, hepatocellular carcinoma was detected in 15 patients coincidentally or during the follow-up period. The intrasubject variability of kinematic parameters was distinctly higher in the children. After subsequent hysterectomy the extent of thermal damage into the myometrium was assessed by light and electron microscopy.

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The suckling-induced release of OT was attenuated, but not abolished, by DCK, while PRL release was briefly stimulated by this agent. Male reproductive health is compromised with increased paternal age, due at least in part, to an increased frequency of de novo germline mutations. Twenty-eight cases of abdominal scar endometriosis from January, 1980 to December, 1993 are reported.

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Computations were validated by comparing simulation results with previously obtained in vitro particle image velocimetry (PIV) measurements. These findings together with previous results showing inhibition of sepsis in mice and dogs suggest that protein tyrosine kinase (PTK) blockers of the AG-556 family may be considered in the management of human autoimmune disorders such as multiple sclerosis (MS). A possible general role for LC8 in macromolecular assembly is discussed. Optical images were interpreted as correct in six of eight cases, with one error attributed to the age of the clot, and one small clot not seen.

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Magnetic resonance imaging (MRI) methods with shorter acquisition times are considered. Besides the use of adjuvants, the pDNA vector itself can be designed to maximize survival in nuclease-rich environments.

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The oblique branch of the supraorbital artery (OBSOA) most often anastomosed with either the transverse frontal artery or the frontal branch of the superficial temporal artery at the lateral orbital rim vertical line. Immunohistochemistry with TrkB, TrkA, and p75 antisera revealed that VGNs made TrkB and p75 proteins, but not TrkA protein.

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Embryos were harvested to see the effect of temperature variations of injected saline on neural tube formation. Results obtained using the recombinant yeast hybrid GAD67/65 were very similar to those obtained using 125I-labelled porcine GAD.

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Sequencing by tandem mass spectrometry, however, was unsuccessful due to fragmentation of the alkylating moiety from the peptide. Hypolipidemic effects of metformin in hyperprebetalipoproteinemia.

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Environmental tobacco smoke and middle ear disease in preschool-age children. Dispensary treatment as a method of active prevention of malignant tumors of the oral cavity

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Damage to the vascular endothelium of diabetic patients can be assessed by analysing blood samples for the number of circulating endothelial cells with mitochondrial DNA deletions. Subcellularly, AZ-LI was observed both in the nuclei and cytoplasm of labeled motoneurons. Mechanism of sensitization with chlorophyll and related compounds of the reaction of photoreduction of certain stains There were 48 different novel sounds, 32 of which were repeated, and about two-thirds of which represented familiar sound concepts. The enzymes protect the cells against toxicants by conjugating them to glutathione.