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Imidol (Imipramine)

Imidol a synthetic tricyclic derivative, antidepressant Imidol enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imidol has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. Check for active clinical trials using this agent.

Other names for this medication:
Imipramine, Tofranil, Antidep, Depramine, Depranil, Deprinol, Depsonil, Imidol, Imipramina, Impril, Janimine, Melipramin, Talpramin, Tolerade,

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Imidol is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain.

Imidol tablets are also used to treat enuresis (bedwetting) in children.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

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A systematic request for product monographs was made between 1999 and 2002 to manufacturers registering new medicines in Spain. Previous analysis of the angiotensin I-converting enzyme (ACE) gene in this laboratory showed that primary mesangial cells in culture are able to express ACE mRNA. Electrosmog as a health risk factor: sources of artificial electromagnetic fields, evaluation of health risk, prevention methods

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Another is directed roughly in the direction of the acyl transfer leaving group, and a third in the direction of the S2 site. The ob mRNA levels in the adipose tissue from Wistar fatty rats was unequivocally augmented and continued to rise in the process of obesity. Moreover, together with both regulatory and catalytic subunits, which constitute the PKA holoenzyme, a protein with a molecular mass of approximately 200 kDa was copurified, and results from gel-filtration chromatography showed that it was associated with a fraction of PKA.

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Application of burden of disease methods suggests that there has been progress along the epidemiological transition. Purification and characterization of galanin and scyliorhinin I from the hybrid sturgeon, Scaphirhynchus platorynchus x Scaphirhynchus albus (Acipenseriformes). A 58-year-old woman presented with typical cutaneous features of lichen planus (LP). Comparison of LC detection methods in the investigation of non-UV detectable organic impurities in a drug substance.

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When OspA antibody was administered to mice 48 h after tick attachment, spirochetes persisted in the nymphs and the mice were not protected despite the presence of circulating antibodies in the host as well as in the tick blood meal. Half of the slices not exposed to TSH initially were then incubated with buffer and half were exposed to 5-100 mU/ml TSH. Basement membrane was observed by electron microscopy at some sites beneath groups of epithelial cells, but did not extend continuously beneath these cells. Its occurrence is not linked with agriculture or irrigation but is closely related to other man/water contacts in the rivers. The psychiatric consultation-liaison program and posttraumatic stress disorder due to burns

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The antioxidant properties of aqueous extracts from the dinophycean flagellates Gymnodinium impudicum and Alexandrium affine and the raphidophycean flagellate Chattonella ovata were examined. In rabbits, epidural placement of freshly mixed cement causes slight thickening of the dura. These results suggest that endothelin does not play a direct role in the pathophysiology of renovascular hypertension. These results suggest that Claspin has properties of both a tumor suppressor and an oncogene. Severe sepsis due to severe falciparum malaria and leptospirosis co-infection treated with activated protein C.

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The factors that effect resectability, major morbidity, early mortality, and survival in advanced stage gastric adenocarcinoma patients are evaluated. GENERAL CONSIDERATIONS CONCERNING DRUG PARTICLE SIZE AND PARTICLE SIZE DETERMINATION. Correlational study designs, a small number of studies, a lack of clinical validation for many measures, and possible heterogeneity. It helps in making a diagnosis and developing a management plan.

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The clinical state of parodontium estimated by means of GI and PBI evaluating quality changes in the gum. A nonparallelism of inhibition of the three different steps of the secretory process depending, with respect to its extent,on time after pCPA-application (4-72 h) and on the concentration of pCPA (1-10(-5) to 1-10(-2) M) in the incubation medium was found.

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Diabetes has a high burden of illness both in life years lost and in disability through related co-morbidities. Investigations demonstrated that IAH is able to induce loss of intravascular volume, organ hypoperfusion, ischemic organ damage and multiple organ failure within 4 to 6h. These dynamic changes are assessed by acquiring a time series of images using a gradient-echo asymmetric-spin-echo sequence (GREASE), a technique in which two images are acquired for each excitation--one during the gradient echo, and one during the latter part of the spin echo.

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Molecular cloning and characterization of a human protein kinase that specifically activates c-Jun N-terminal kinase. Research has shown that the risk of disease transmission by bovine embryos is minimal therefore regulations are evolving to recognize this potential. Representation of objective similarity among three-dimensional shapes in the monkey. Effect of alcohol on Glasgow Coma Scale in head-injured patients. Quantitative EMG studies including concentric needle motor unit action potentials, interference pattern, macro-EMG and fiber density have allowed different measures to be made of the motor unit.

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Moreover, in our experimental conditions, depletion of intracellular levels of putrescine and spermidine by alpha-difluoromethylornithine (DFMO) delayed the onset of apoptosis by at least a day or so. A quantitative histological analysis of the dilated ureter of childhood. LCRF immunostaining was observed in villus tip enterocytes of the small intestine and was most prominent in the duodenal portion. These deficits seem to be unrelated to motor impairments because B(a)P had no effect on locomotor activity and motor coordination. General method for plasmid construction using homologous recombination.

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This study showed that bone marrow-derived mesenchymal stem cells cultured with rhBMP-2 and basic FGF act as a substitute for autograft in lumbar arthrodesis. In addition to membership in the same category, preoperational subjects required that both exemplars be typical before categorizing them together on the Sample-Match Task. It has become clear that environmental factors can be at the origin of such epigenetic changes.

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A 40-year-old woman with acute lymphoblastic leukemia had a visual disturbance OD. The cell fragments were bounded by a plasma membrane, had no nuclei and contained mitochondria and abundant rough endoplasmic reticulum (RER). These results suggest that LAT and NTAL contribute to the maintenance of Erk activation and survival through the membrane retention of the Ras-activating complex Grb2-Sos and, further, that the LAT-Gads-SLP-76-PLCgamma and LAT/NTAL-Grb2-Sos pathways are differentially required for degranulation and survival, respectively. Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride: evidence for a novel disulfide exchange reaction in a covalently cross-linked mutant. Five cases were right-sided endocarditis and two cases were left-sided.

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Clinical classification includes an analysis and categorization of the individual diseases. Motor co-ordinates in primate red nucleus: preferential relation to muscle activation versus kinematic variables.

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Uterine thermal balloon therapy for the treatment of menorrhagia: the first 300 patients from a multi-centre study. All four subjects belonged to a large, multigenerational Norwegian family and were known to carry a frame shift mutation in the TIMM8A gene. Pseudocholinesterase-activity reduction during cardiopulmonary bypass: the role of dilutional processes and pharmacological agents.

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Pacemaker patients with coronary artery disease and angina pectoris fare better with devices providing AV synchrony and rate increase on exercise provided the programmed upper rate is not excessive. Human trophoblast cell lines were examined for expression of MHC class II transcription factors and for activity of the IFN-gamma signaling pathway. KUNTZE) was found to inhibit release of beta-hexosaminidase from RBL-2H3 cells. These results suggest that decreased nNOS-cGMP system in DRG may play a role in the pathogenesis of diabetic sensory neuropathy. Expression of the p53 tumor suppressor gene induces differentiation and promotes induction of differentiation by 1,25-dihydroxycholecalciferol in leukemic U-937 cells.

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Adult prostate sarcoma diagnosed from tissue spontaneously excreted through the urethra. Pulmonary complications in inhalation injuries with associated cutaneous burn. Current anesthesia literature suggests using saline with an air bubble in the loss-of-resistance syringe. Cerbussowia cerruti Wilhelmi 1901, from the Tunisian Golf (Platyhelminths, marine Tricladida)

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Cryoablation techniques and/or equipment need to be improved in order to safely create more permanent lesions in this arrhythmia substrate. Screening versus design: confessions of an optimistic fence-sitter. SRC utilizes Cas to block gap junctional communication mediated by connexin43. Endometriosis: frequency and correlation between symptomatology and disease stage. Regulating effect of the hematopoiesis-inducing microenvironment on hematopoietic processes as affected by cytostatic drugs

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Triptolide down-regulates bcr-abl expression and induces apoptosis in chronic myelogenous leukemia cells. The use of impregnated curtains does not affect antibody responses against Plasmodium falciparum and complexity of infecting parasite populations in children from Burkina Faso. At the same time, the seasonality of homicide has decreased markedly.

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Fifty-eight all-night polygraphic sleep recordings were obtained on an unmedicated female bioplar (manic-depressive) patient who switched into and out of mania eight times. Self-association of the transactivator HBx protein of hepatitis B virus was investigated using the yeast two-hybrid system. Parathyroid hormone-related protein (PTHrP) as a regulating factor of endochondral bone formation.

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Immunoblot studies on purified laminin 5 subunits demonstrated that patient IgG bound alpha3 alone in 16 patients. There was a sharp task demarcation between RNs and CAs in the three less frequent task categories.

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We analyzed LD in two European flint maize populations, KW1265 x D146 (A x B) and D145 x KW1292 (C x D), under modified recurrent full-sib selection. Mandibular bone fluoride levels and occurrence of fluoride induced dental lesions in populations of wild red deer (Cervus elaphus) from Central Europe.

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The results of VAMP treatment (vincristin, amethopterin, 6-mercaptopurine, and prednisone) are better in children than in adults. Molecular cloning and characterization of a short type peptidoglycan recognition protein (CfPGRP-S1) cDNA from Zhikong scallop Chlamys farreri. Needle electromyography demonstrated irregular bursts of motor unit potentials that were identical to the pattern observed in hemifacial spasm. To test whether abnormal homocysteine metabolism is associated with syndrome X.

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Weight loss, body composition and risk factors for cardiovascular disease in obese children: long-term effects of two treatment strategies. Although feed requirements for work are generally low, feed quality can be so poor that animals are unable to eat enough to meet energy needs for work, and so lose weight during the work season. The pathologic findings showed bronchiolitis obliterans with or without organized pneumonia.

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The goal is to provide sufficient immunosuppression to retard rejection without causing undesirable side effects, including infection and neoplasms. BALB/K mice are usually resistant to infection with the intestinal nematode parasite Trichuris muris and exhibit a Th2 dominated (IL-5, IL-9) response. Further mutation of the A1:U72 base pair, which is conserved in virtually all eukaryotic initiator tRNAs, to G1:C72 in the C35 mutant background yielded tRNAs that were even more active in elongation. Effect of insulin incubation on lipid synthesis by isolated rat adipocytes. Preoperative physical therapy in primary total knee arthroplasty.

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Association between nonsyndromic cleft lip with or without cleft palate and the glutamic acid decarboxylase 67 gene in the Japanese population. A microcolonial test for the recognition of virulent mycobacteria. Additional evidence has been obtained to indicate that it is probably optically stereospecific for d-secondary alkyl sulphate esters with the ester sulphate group at C-2 and with a chain length of at least seven carbon atoms.

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Inter-volunteer variability was 2.4-3.4 times larger than within-volunteer variability. This stimulation contributes toward the development of masculine sexual behavior and mechanisms in the central nervous system that control copulatory reflexes. Thus anetoderma could be another cutaneous sign of the antiphospholipid syndrome.

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The two plasma expanders studied show a close inverse correlation between the alterations of blood flow velocities in the middle cerebral artery and systemic hemoglobin and hematocrit values. The adhesion properties of normal human dermal fibroblast (NHDF) cells on microcrystalline and ultrananocrystalline diamond (UNCD) surfaces were measured using atomic force microscopy. The cytoskeletal intermediate filament characteristics of normal, freshly isolated and subcultured canine retinal pigment epithelial (RPE) cells were studied using immunocytochemistry and immunoblotting techniques. These findings indicate that OA has associated systemic factors that influence corneal cell metabolism.

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3D-based computer-assisted manufacturing of individual models facilitated surgical planning of complex midfacial injuries. Primitive systems of innate immunity, such as the complement system, may play a role in this distinction.

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Normal bladder function in utero is essential to normal development of the entire fetus, and in utero modulation of bladder dysfunction may be feasible as our understanding and diagnostic acumen increase. Patients residing in the zone neighbouring the Chernobyl station developed more frequently cardiac failure. Two hundred twenty-eight male broiler chicks (Columbia x New Hampshire) were given feed amended with autoclaved culture material of Fusarium proliferatum containing fumonisin B1 (FB1) at 61, 193, and 546 ppm, fumonisin B2 (FB2) at 14, 38, and 98 ppm, and moniliformin at 66, 193, and 367 ppm in 3 separate feeding trials (amounts of toxin in each trial, respectively). Interfering with alphavbeta3 binding inhibits osteoclast-mediated bone resorption, and thus demonstrates the potential utility of alphavbeta3 antagonists for therapy of osteoporosis. Unique chemical reactivity of His-21 of CRM-197, a mutated diphtheria toxin.

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Circulating concentrations of leptin are exceedingly low during the acute stage of anorexia nervosa. In all preparations except for the somatic extract, the activity was characterized as cyanide-sensitive CuZn SOD. To evaluate the therapeutic effects of a GnRH agonist (GnRH-a), leuprolide acetate (LA) plus a pill containing ethinyl E2 plus cyproterone acetate (CPA) in a group of women with severe hirsutism who were unresponsive to oral contraceptive (OC) therapy. In foals, after intake of the first colostrum, globulin increased within 1 day in blood plasma, but remained at lower concentrations than those measured in mare plasma. One hundred fourteen patients 16 to 25 years of age were randomized to tonsillotomy (TT) with radiosurgery (RF) (Ellman International) or to cold tonsillectomy (TE).

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We used siRNAs to knock down the levels of TES, a focal adhesion protein, in HeLa cells. Effects of adult nutrition on female reproduction in a fruit-feeding butterfly: the role of fruit decay and dietary lipids. In order to achieve bone regeneration, osteogenic genes (mainly from the bone morphogenetic protein family) can be delivered either directly into the target tissue, or by using adult stem cells, which are later implanted into the target site. Psychological assessment showed a personality disorder with depressive and paranoid features in the mother. CD4 T cells isolated from allopurinol prevention tumor lysis syndrome pathophysiology the CD28-deficient mice can receive costimulatory activity from CD40L-induced B cells, demonstrating that the induced molecules can costimulate T cells by a CD28-independent mechanism.

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m-THPC-mediated photodynamic therapy of malignant gliomas: assessment of a new transfection strategy. This has proved successful in the management of persistent middle ear effusion despite numerous piroxicam pharmacy previous short- and intermediate-term tympanic membrane ventilation tubes.

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Insulin citoles medicine cabinet lispro did not alter the glycosylated haemoglobin values in the largest multicentre study, although the postprandial glucose concentrations were significantly lower. A total of 2961 subjects aged 50-74 years were invited by mail to perform a one-day immunochemical FOBT without any dietary restrictions and with a positive threshold put at 100 ng/ml. Plasma exchange is of proven efficacy in the treatment of thrombotic thrombocytopenic purpura (TTP).

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CuFe2O4/activated carbon magnetic adsorbents, which combined the adsorption features of activated carbon with the magnetic and the excellent catalytic properties of powdered CuFe2O4, were developed using a simple chemical coprecipitation procedure. However, the previously reported increased expression of CD38 and HLA-DR was not confirmed. The extent of wound enlargement immediately following wounding of the irradiated animals was decreased as compared to the controls. However signal intensity of stationary tissue were more suppressed with a shorter TR resulting in a larger signal difference to noise ratio of the flowing zopax tabs for guitar fluid. We also observed that inverted repeats recombined as efficiently as direct repeats.