Pre-treatment with dihydroergotamine and, to a lesser extent, Imigrane, attenuated this increase. -The evaluation of the effectiveness and tolerance of Imigrane in abortive treatment of migraine attacks (open multicenter trial). In this double-blind, randomized, crossover study, 16 adult migraineurs fulfilling International Headache Society (IHS) criteria for migraine with or without aura who had failed to receive adequate relief from triptans treated one migraine with each treatment: Imigrane 50 mg plus metoclopramide 10 mg or Imigrane 50 mg plus placebo to match metoclopramide.
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