Indophtal is used to relieve moderate to severe pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). Indophtal is also used to treat pain in the shoulder caused by bursitis (inflammation of a fluid-filled sac in the shoulder joint) and tendinitis (inflammation of the tissue that connects muscle to bone). Indophtal immediate-release capsules, suspension (liquid) and suppositories are also used to treat acute gouty arthritis (attacks of severe joint pain and swelling caused by a build-up of certain substances in the joints). Indophtal is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

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To develop appropriate research-based interventions, more data are needed on specific aspects of these demands. Selective dorsal rhizotomy for children with cerebral palsy: the Oswestry experience.

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Multilevel surface nano- and microstructuring via sequential photoswelling of dichromated gelatin. A case of polyarticular sepsis from group G streptococcus is described in a patient with rheumatoid disease and decubitus ulcers. COPD: criteria for diagnosis and classification of disease severity Unilateral corneal ectasia after laser in situ keratomileusis in a patient with uncomplicated photorefractive keratectomy in the fellow eye.

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Adjuvant-induced thymus-derived suppressor cells of cell-mediated tumour immunity. We provide scientists and clinicians with an introduction to the basic principles and methods of positron emission tomography (PET) and summarize the recent research and clinical applications of PET in the urological field.

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Non-secretory multiple myeloma presenting as primary plasma cell leukaemia. Ninety protein spots in the developing seeds are up-regulated and 19 individual proteins were identified, the majority of these are intermediates of seed storage synthesis and protein folding. An increased number of ASMA-positive cells was detected in fibrotic interstitium.

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In the present study, the cloning is described of murine NR4, a previously unrecognized receptor identified on the basis of sequence similarity with members of the hemopoietin receptor family. Ketorolac was no better than the other analgesics studied but was associated with a higher number of mild side effects.

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In the 3 cases there was necessity of practicing trans-scrotal orchiectomy, since they went later. Further investigations on the p-nitrophenylphosphatase activity of intact Ehrlich ascites tumor cells. The study of administration of the rest of the substances (CPS S-I, SPP, CS) to rats revealed that CPS S-I highly inhibited formation of stone in kidney. Comparative study of cyclosporin A, cyclosporin G, and the novel cyclosporin derivative IMM 125 in isolated glomeruli and cultured rat mesangial cells: a morphometric analysis.

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Subcutaneous alemtuzumab is more convenient and better tolerated but may be associated with some patients forming anti-alemtuzumab antibodies, particularly those patients who were previously untreated. While such trials may influence practice in an appropriate way, they must likewise be reviewed critically to ensure the validity of the results and generalizability to patients seen in a nontrial setting.

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Positive correlation of serum leptin with estradiol levels in patients with polycystic ovary syndrome. The EGFP-MBD-nls protein was used to follow DNA methylation in situ under physiological conditions. Levels of C-reactive protein and complement 4 fraction in hyperthermia secondary to microsurgical vascular decompression for trigeminal neuralgia The 22-kDa product represented the N-terminal 195 amino acids of the cilium adhesin preprotein, confirming that the hydrophobic leader signal sequence is not cleaved during translocation across the membrane.

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Although in addition to blood, increased brain and cerebrospinal fluid betaE levels are also associated with pain, the majority of studies have concerned blood betaE levels. These cases required bone reconstruction without suitable recipient vessels that existed near the defect. However, amidation of the CO2H-terminus does have a large effect on metabolic stability in the adrenal slice assay.

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The NOS immunoreactive presynaptic dendrite boutons were found both within and outside glomeruli and established both pre- and post-synaptic relationships with other elements. Bicalutamide monotherapy at 50 mg/day appears inferior to castration in overall objective and subjective response rates.

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Growth, spread, and extracellular localization of herpes simplex virus 1 in Vero cells in the presence of an anti-gD plaque inhibiting monoclonal antibody. In short stressed ewes the significant augmentation of mRNA encoding GnRH-R was detected in the preoptic area, entire hypothalamus, stalk/median eminence and anterior pituitary gland. The ATLS Courses have become widespread throughout our Country, which today is the fourth in the world for number of courses held every year. LE cell phenomenon: nuclear IgG deposits inhibit enzymatic cleavage of the nucleus of damaged cells and support its phagocytic clearance by PMN. The two children gradually gained weight and improved remaining in stable remission.

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Biological sequence databases are currently being re-engineered to make them more efficient and easier to use. PKC-mediation of the p53 U.V.-response was further ruled out by the reactivity of the activated p53 to C-terminal antibody PAb 421. It is often restricted to its most typical form-Chiari II syndrome. Administration of ACE inhibitors in the early postoperative period to patients with severe postcardiotomy dysfunction caused improvement in tissue perfusion with decreases in mortality, morbidity, and length of hospital stay. LL95 monoclonal antibody mimics functional effects of ZP3 on mouse sperm: evidence that the antigen recognized is not hexokinase.

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English-language literature published between 1966 and 2005 was reviewed. We report on an 82-year-old male with adrenal myelolipoma that had been incidentally discovered during evaluation for another condition.

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For a quickly relaxing component, an anomalous increase in the coefficient of self-diffusion with the time of diffusion took place. In the presence of SDS, marked quenching occurred in the fluorescence emission spectra with a blue shift of the maximum emission wavelength from 332 to 326 nm. These data suggest that Li administration not only blocks the adenyl cyclase-cAMP system in the renal cortex, but it may also interfere with a step distal to the formation of cAMP, since the phosphaturic effect of both PTH and cAMP was markedly diminished in Li-treated animals. To assess the effect of impact with a nonpenetrating captive bolt pistol in pigs by studying the resulting traumatic brain injury (TBI) and to compare the pathological changes with those found previously in the brains of sheep using a similar experimental paradigm.

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We evaluated the virulence of Pseudomonas aeruginosa carrying bla(IMP), a metallo-beta-lactamase gene, and the efficacy of ceftazidime, imipenem-cilastatin, and ciprofloxacin in the endogenous bacteremia model. The emotive and cognitive reactions in temporary pharmacological menopause Effects of photo-induced graft polymerization of 2-methacryloyloxyethyl phosphorylcholine on physical properties of cross-linked polyethylene in artificial hip joints. Several corticosteroid preparations were administered to rabbits, in different dosages and for different periods of time in an attempt to produce maximal effects. Steel factor appears important for the development of certain classes of IC, and IC-MY appear to be involved in the generation of electrical rhythmicity in the small intestine.

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The chemical action of gun powder gases on biological tissues in a point-blank shot This risk varies substantially according to type of alcoholic beverage: beer confers a larger risk than spirits, whereas moderate wine drinking does not increase the risk. Our experiences in treating patients with Hodgkin disease in the last decade Analysis of the concentrations of d-F and its main metabolite d-fenfluramine (d-NF) in brain excluded any pharmacokinetic tolerance.

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Randomized controlled trials (RCTs) reported conflicting results on the impact of high-dose chemotherapy (HDCT) and autologous stem cell transplantation in the first-line treatment of patients with aggressive non-Hodgkin lymphoma (NHL). Since the fibrates are drugs of choice in HLPIIb, we additionally evaluated the effect of fibrates on the cytokine levels. Our observations lend strong support to the hypothesis that anti-LHRH vaccine can be effectively used on the management of prostate carcinoma. In conclusion, these data suggest that bryostatin-1 is a potent antileukemic agent in vitro that may be potentially useful for clinical studies.

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Although extracellular signal-regulated kinase (ERK) is critical to iNOS expression, endotoxin/cytokine-stimulated phosphorylation of ERK1/2 was not significantly inhibited by baicalein. Breast milk levels of zinc and omega-6 polyunsaturated fatty acids and growth of healthy Chinese infants. Localization and characterization of the dimerization domain of holliday structure resolving endonuclease VII of phage T4. The inhibition of HDAC enzymes by HDAC inhibitors shifts the balance between the deacetylation activity of HDAC enzymes and the acetylation activity of histone acetyltransferases, resulting in hyperacetylation of core histones. Direct DNA sequencing showed no alteration of p53 gene exons 5-8 in any sample of 10 benign ameloblastomas and 1 metastasizing ameloblastoma.

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No change was shown in the control group between baseline and follow-up 1, and a decrease was shown in the total number of questions from follow-up 1 to 2. Systematic data collection was carried out by review of all medical records. Three-dimensional treatment planning, once considered a special procedure, is the standard of care for many patient presentations.

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Comparison of right- and left-sided pectoral implantation parameters with the Jewel active can cardiodefibrillator. Integrin receptor-targeted transfer peptides for efficient delivery of antisense oligodeoxynucleotides. In addition, the RNA transcription and replication of this virus are reviewed. These findings indicate that patients with liver cirrhosis have hyperfibrinolysis. While it is clear that the presence of glaucoma and use of beta-blockers correlate with vascular parameters, from this study it is not possible to distinguish pathogenic factors from pathologic results of disease or drug effects.

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Other analogues, such as dihydroxyphenylalanine, thioproline and pipecolic acid accelerated protein breakdown but probably indirectly via an inhibition of protein synthesis. To evaluate the value of transesophageal color Doppler echocardiography in the diagnosis of intrathoracic masses. The purpose of this study was to assess the acute systolic and diastolic effects of a nonstimulated muscle wrap in chronic heart failure induced by rapid ventricular pacing in canines. The objectives of this study were to investigate biomechanical effects of not only tumor sizes within the thoracic vertebral body but also its involvement of other spinal components on the probability of mechanical failures of the thoracic spine. A conceptual model is proposed by which disruption of these different genes leads to the development of acute leukemia.

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On the other hand, mRNA expression of p50/p105 and p65, subfamilies of NF-kappaB, was enhanced in primary cells isolated from some ATL patients. Overall, results suggest that the reliability of chart review diagnosis is comparable to that obtained from interviews of live patients when experienced raters are used and diagnostic base rates are high enough to produce stable estimates of reliability. A mutant defective in sboA showed significantly reduced growth on L-sorbose, indicating that the SboA enzyme is required for efficient growth on L-sorbose.

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A retrospective review over 3 years identified 20 women who were treated with single-agent intravenous PLD for recurrent ovarian carcinoma. EAM using a specific parameter setting proved highly effective at identifying the MDAI in MAT, even in patients with previous surgery and multiple re-entrant loops.

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In 21 patients, lung cancer was suspected preoperatively, based on radiographic findings of an ill-defined margin, pleural indentation and spicular radiation. Thus, the principle for staphylococci ELISA based on monodisperse magnetic beads is a way for rapid detection of staphylococci in milk and possibly also for detecting staphylococci by direct testing of other clinical specimens. Free energy profiles were obtained from molecular dynamics simulations of the reaction using umbrella sampling and weighted histogram analysis techniques. In general, the higher the water temperature, the faster the immune response of fish to the vaccine. It was possible for the patients to avoid surgical intervention in a number of complicated periapical endodontic situations by means of Nd:YAG laser-assisted sterilization.

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The prenatal identification of fetal compatibility in neonatal alloimmune thrombocytopenia using amniotic fluid and variable number of tandem repeat (VNTR) analysis. Five children had a favourable outcome, with a mean follow-up of 80 (29-121) months post-renal transplantation. Vps4 contains an N-terminal microtubule interacting and trafficking (MIT) domain, which has previously been shown to be required for recruitment to endosomes, and a single AAA ATPase domain, the activity of which is required for Vps4 function. Ultracentrifugation of serum samples allows detection of hepatitis C virus RNA in patients with occult hepatitis C. It is argued that felt empathy evokes cognitive and emotional processing conducive to important health-promoting responses.

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Electron-microscopic observations of normal coelomocytes from the earthworm, Lumbricus terrestris. Dioxin concentrations were measured as 0.050 and 0.075 pg TEQ.m(-3), corresponding to a daily intake between 0.007 and 0.01 pg TEQ. The effect of clozapine on the sleep pattern in the rat was studied after a single injection (2.5--20 mg/kg) and after daily administration for 11 consecutive days (2 X 20 mg/kg/day).

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Technical development in acquisition and postprocessing of spinal cord MRI is likely to increase in the near future our understanding of disease pathobiology through an increased ability to define the nature and location of spinal cord damage as well as through an accurate functional mapping of its activity, which might have an adaptive role in limiting the consequences of structural CNS injury due to MS. Biological and immunological aspects of hepatitis C virus infection in chimpanzees. As of April 6, 2004, no published reports have been found describing efficacy or safety with pediatric use of this reagent.

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After reading this article and taking this test, the reader should be able to: 1. The need for international guidelines concerning the off-label use of rFVIIa is outlined as well as the need for methods to control the efficacy of rFVIIa objectively. In this paper, the enzymatic methods for hepatocyte isolation in some mammalian species are reviewed, and methods for evaluating cell purification and assessment of cellular morphology and function are also examined.

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Phase properties of the quantized single-mode electromagnetic field. Indirect evidence indicates that at least 3 other affected Quarter Horse stallions have stood or are standing at stud in Australia. Using electrophoretic mobility shift assays, we studied the relative activity of the five major regulatory sites in the rat prodynorphin promoter. Products were easily amplified by PCR and digested with restriction endonucleases for beta thalassemia typing as well as for HLA-DQA1 gene typing. Verotoxins inhibit the growth of and induce apoptosis in human astrocytoma cells.

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Comparison of findings in plain radiography and conventional tomography with findings in plain radiography and magnetic resonance imaging of the upper cervical spine in consecutive patients with rheumatoid arthritis and with known or suspected abnormalities of the cervical spine. The 16S late mRNA from SV40 directs the synthesis of the major viral structural protein, VP1. Preserved obstacle avoidance during reaching in patients with left visual neglect.

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The QOL outcome supports the superiority of ET over the other two interventions in older people who have recently fallen. To study laser treatments of PWS with the diffusion approximation, FEM is an effective method to calculate the coagulation patterns within specific blood vessels.

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This finding reflects two critical weaknesses of the project--nontimely data and lack of information about the process of care. There is increasing competition to find a glucocorticoid formulation or analogue that enhances therapeutic effects while reducing adverse effects. The effect of knowledge to consent allows a more focused, relevant and modern approach to choice in health care. Levels of organochlorine contaminants were elevated to depths of 90 cm in the sediment, suggesting that the surface layer is a source of contaminants to the deeper sediment.

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The capillary rise of liquid in a cylinder bank is examined in order to study the capillary pressure variation perpendicular to the direction of the cylinders. Three different classes of proteins that regulate the GTP binding and GTP hydrolytic activities of the Ras family members have been identified.

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We have detected cytoplasmic anti-Golgi antibody (AGA) during a routine immunofluorescence test for detecting autoantibodies. A 45-year-old woman developed hypersensitivity to dapsone when this drug was used to treat corticoid-dependent asthma. In this study we compared the development of the rat embryonic ventral mesencephalon transplanted together or without striatal tissue into the cerebral cortex of adult rats. Proteoglycans that carry abundant chondroitin sulfate and keratan sulfate side-chains, most likely aggrecans, were detected by safranin O in the fibrocartilaginous zone of the condyle in parasagittal sections.

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Echocardiographic abnormalities, notably left ventricular hypertrophy, have been shown to be associated with adverse outcome in patients on dialysis. Microscopically, the tumor involved the submucosa and partly invaded the muscular layer. Minimum fragments of the heparin molecule able to produce the accumulation and change of the sulfation pattern of an antithrombotic heparan sulfate from endothelial cells.

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We experienced a girl diagnosed as having PNH with spontaneous recovery from pancytopenia, and analyzed the GPI-anchor expression on peripheral blood cells. The purpose of this report is to provide an illustrative case of spontaneous hepatic and renal hematomas that occurred during a pregnancy complicated by preeclampsia and the HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome. A contrast-enhanced MRI study performed immediately after therapy showed a good correlation of the size of an enhancing rim around the lesion with the 60 to 65 degrees C isotherm. The auditory cortex of the mouse: connections of the ultrasonic field.

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Current strategies for management of hypertensive renal disease. The specimen is from a new species of Komba, a genus previously known from early Miocene occurrences in western Kenya and northeastern Uganda.

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If IIS status is reversed early in adulthood, similar to the effects of another intervention that reduces adult mortality in Drosophila, dietary restriction (DR), there is a complete switch of subsequent mortality rate to that of flies chronically exposed to the new IIS regime. Veterans Affairs Palo Alto Health Care System, Palo Alto, California, United States. However, the results also indicate that novelty-induced running does not alter c-Fos induction in a phase-specific manner in the IGL. These include production of epidermal growth factor (EGF) receptors (EGFR) and their ligands which are important auto/paracrine regulation of lung tissue formation in health and tumor growth. Elimination of CD13-positive PBMCs removed productively in vitro- and in vivo-infected cells, as demonstrated by detection of infectious virus only in PBMC fractions containing CD13-positive cells.