Insup is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat heart failure. Insup is an ACE inhibitor and works by relaxing blood vessels so that blood can flow more easily. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to help protect the kidneys from harm due to diabetes.

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To evaluate the effects of genetic and environmental factors on the bone mass, we determined the bone mineral density (BMD) in the total body, the lumbar spine and in the femoral neck in 23 Japanese twin pairs including 21 monozygotic (MZ) pairs, applying dual-energy X-ray absorptiometry. Adult caregivers (eg, mother, father, grandparent) of dependent minors who require transfer assistance. V(D)J recombinase activity was measured in an array of human cell lines derived from hematopoietic malignancies representing various lineages and developmental stages. A thin cotton bedcover covered the mattress, electrodes, and conductive textile, and the participants were positioned on the mattress over the bedcover. Simultaneous intraluminal irradiation and hyperthermia treatment for esophageal carcinoma

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Although the number of thymocytes that survived irradiation remained low for several days post-irradiation, further colonization by donor cells was not possible, unless performed within 6 h after irradiation. Technology alone will not improve patient outcome or control costs.

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The adenoid tissue is an immunecompetent lymphoid organ, which has the capacity of reacting against numerous antigens. Symptomatic hyperekplexia is a relatively rare entity, but has been documented in various, mostly brainstem diseases. Induction of HSP60 and HSP70 in cholesteatoma epithelium may also be related to hyperproliferation and active differentiation of basal keratinocytes, which cause the accumulation of keratin debris, a characteristic feature of cholesteatoma. Local application of recombinant active-site inhibited human clotting factor VIIa reduces thrombus weight and improves patency in a rabbit venous thrombosis model. If the vaccination is given together with a suitable dose of long-acting androgen, contained in an adequate delivery system, the regimen may be used for the regulation of male fertility.

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TAP is the second cellular RNA binding protein shown to be directly involved in the export of its target RNA. Rev-erbA alpha and RVR are orphan nuclear receptors that function as dominant transcriptional silencers. We also outline previous hypotheses of the aetiology of venous ulceration, including arteriovenous microanastomoses, stasis and oedema. Mutation of prgZ decreased the sensitivity of donor cells to pheromone, whereas inactivation of the chromosomal E.

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Aplastic anemia, liver necrosis and hemorrhage in chickens after neonatal infection with infectious bursal agent For these reasons, alternatives to radical surgery have been sought. The survival of patients who underwent combined surgery and TACE was 38 and 17 months in the two gastrinoma cases, more than eight months in one gastrinoma case and more than 20 months in the insulinoma case (these 2 patients are still alive). Clinical and laboratory experience with chloramphenicol of Czechoslovak production

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Challenge exposure to aluminium welding with flux-coated electrodes, as well as with electrodes without flux, elicited marked asthmatic reactions. The outcome measure was the medication adherence rate registered in the electronic monitors. An approach to selecting pacing modes for specific abnormalities is outlined. Differential response in choice reaction time following apomorphine based on prior dopaminergic treatment.

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Social and cognitive approaches to depression: towards a new synthesis. If bone disease of prematurity is to be prevented, the amounts of calcium and phosphate must be adequate, as demonstrated by laboratory tests, the most important being calcium and phosphate in urine and alkaline phosphatase activity in serum. The blood level determinations of PAS and isoniazid with vanillin.

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Pipetting embryos is necessary for many protocols, from in vitro fertilization to collecting embryos prior to analyzing gene expression by microarrays. Current treatment regimens are associated with substantial side effects, especially hematologic and neuropsychiatric side effects, that can lead to nonadherence, dose reduction, and treatment discontinuation. Data collected included age, sex, time of symptom development, type of initial treatment, and response to GLO2 administration. HISTOCHEMICAL STUDIES ON GLYCOSIDASES OF THE RAT OVARY AND PLACENTA. Binding of avian testicular homogenate with rat follicle stimulating hormone and inhibition of the binding by hypophyseal extracts of lower vertebrates.

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We demonstrate that T-cadherin is enriched in a minor detergent-insoluble low-density membrane domain and co-distributes with caveolin, a marker of caveolae. Transcripts for the macrophage inflammatory protein-1 and tumor necrosis factor-alpha were first detected on day 21 postinfection, with higher levels in mice after development of the posttreatment meningoencephalitis, whereas granulocyte macrophage-colony stimulating factor was detected only in animals that developed posttreatment reaction. Atrioventricular (AV) canal motions and blood velocities of embryonic chicks at Hamburger and Hamilton (HH) stages 17, 21, and 25 were quantified using ultrasonography.

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The evaluation criteria for noncontact Er:YAG ablation were done. However, the molecular mechanisms are poorly understood at present, although the role of several signal transduction pathways have recently been implicated in regulation. Can cytokines prolong survival in ampullary neuroendocrine carcinomas?

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Incomplete relaxation of the left ventricle (LV) affects LV filling, but the subsequent effect on LV systolic function remains unclear. Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level.

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At any time following infection, a small percentage of the cells were positive for rat virus antigens as determined by immunofluorescene assay. Prophylactic oophorectomy in inherited breast/ovarian cancer families.

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Epidermal growth factor receptor (EGFR) in whole testis was measured, as were the activities of c-Src kinase, protein tyrosine kinase (PTK), mitogen-activated protein 2 kinase (MAP2K also termed as Erk2), protein kinase A (PKA), and protein kinase C (PKC). Rate coefficients for populating excited levels of Ne-like ions by inner-shell ionization of Na-like ions. Interestingly, although avirulent or heat-killed Listeria induced only minimal production of IL-12 by macrophages, the immunogenic combination of heat-killed bacteria and rIL-12 was highly stimulatory for IL-12 production.

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Differences on diagnostic validators (most importantly family history) further support the distinction of melancholic MDE between BP-II and MDD, and support DSM-IV classification. The style of application for psychotherapy--whether one family member is registering the family as a whole or the patient seeks help only for himself--makes the difference.

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Compartment syndrome in the leg requiring fasciotomy after bicillin injection in the thigh. This compound suppresses gonadal estrogen secretion prior to hormonal stimulation. permit to perform the dissection between the vagina and the urethra, the suture of the vaginal stump and the anastomosis between the neo-introitus vaginalis and the vagina under direct vision. These findings suggest that peptide ligand structure can induce conformational changes in the Kb heavy chain which alter the rates of cell surface beta2m exchange, and provide further evidence for peptide-dependent fluidity of the class I heavy chain. Assignments of several heme vibrational modes as well as iron-ligand stretching modes are made to serve as a basis for comparing the structure of the enzyme to that of other oxygen reductases.

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The amebacidic properties of some 2-nitrobenzofuran substituants A transient (9 days) treatment with rhBMP-2 abolished the rhTGF-beta2 response of HBMS cells on ALP activity. aeruginosa LPS acts indirectly through osteoblasts to induce bone resorption. For 23 patients, the described technique was used to treat concave alar rim deformity, whereas for 5 patients, who had thick and sebaceous skin, it was used to prevent weakness of the alar rim. Fibrinogen was measured in 5095 men and 4860 men aged 40-59 in a random population sample from 25 districts of Scotland recruited during 1984-87: the Scottish Heart Health Study.

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Cells releasing serotonin at maximal rates were investigated by transmission electron microscopy. The accumulation by oysters of polycyclic aromatic hydrocarbons (PAH) from coal dust entering the estuarine environment has been postulated in the vicinity of coal transfer operations. We report here the characterization of a new SAM maintenance mutant, sha1-1 (shoot apical meristem arrest 1-1), that shows a primary SAM-deficient phenotype at the adult stage. Erratum: Virtual photons and causality in the dynamics of a pair of two-level atoms tularensis, which causes the most severe form of tularaemia, is usually confined to North America.

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To examine the association of radiographic measures of heart size with mortality from coronary heart disease. Neither of these horses could be saved, despite intensive treatment. We now provide evidence suggesting that the MG formation may be a prerequisite for free radical-mediated apoptosis. The purpose of this randomized controlled trial was to examine the effects of balance exercises on proprioception.

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A survey of staff opinion using anonymous questionnaires was conducted simultaneously in five French psychiatric hospitals in January and February 1995. Finally, we indicate that SARS probably propagates in small-world networks associated with human contacts and that the biological nature of individuals and social group properties are factors more important than the heterogeneous rates of social contacts among individuals.

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The gel was suspended in a buffer containing 5-hydroxy-indole-3-acetic acid as an antioxidant and incubated for 2 min with L-cysteine and D-L-dopa at 37 degrees C. The effect of chronic retrovirus infection and immune dysfunction on the P-450-mediated activation of acetaminophen in mouse liver microsomes.

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These findings demonstrate that histamine plays a potential role in the induction of airway remodeling mediated by the induction of lung fibroblasts proliferation and CTGF expression. CANCER OF THE RECTUM IN THE RECORDS OF THE INSTITUTE OF ONCOLOGY AND OF THE 2D SURGICAL CLINIC IN KRACOV, 1952-1961 This study examined the construct validity of the African-American and Hispanic versions of the Oucher Scale as measures of pain in 104 children ages 3 to 12 years old.

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In the developing brain, the expression of VEGF receptors in the perineural capillary plexus and in capillary sprouts which have invaded the neuro-ectoderm correlated with endothelial cell proliferation and brain angiogenesis. The flap, which is half the height of the defect, is elevated and inset to cover the defect.

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Serum HLA-A9 antigens were found by immunoprecipitation and gel electrophoresis to consist of a 45,000 m.w. A variant subline of Chinese hamster cells (line CHO) was isolated that had increased resistance to detachment from the substratum. Sixteen patients with stage III idiopathic macular holes underwent pars plana vitrectomy, removal of the posterior hyaloid, peeling of fine epiretinal sheets along the edges of the holes, and fluid-gas exchange.

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Immunization of common marmosets with Epstein-Barr virus (EBV) envelope glycoprotein gp340: effect on viral shedding following EBV challenge. Determination of gene usage by differential polymerase chain reaction product hybridization. We used 25 premature newborns of corresponding gestational age and normal prenatal Doppler sonographic findings as a control group. Our results establish that inhibition of GSK-3 abrogates NFkappaB binding to its target gene promoters through an epigenetic mechanism, enhances apoptosis in CLL B cells ex vivo and identifies GSK-3 as a potential therapeutic target in the treatment of CLL.

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The treatment of violence and victimization in intimate relationships. Ultrastructurally, the underlying feature in all livers was proliferation of smooth endoplasmic reticulum (SER) displaying species variation. Hypothermia was found to attenuate nitroglycerin-induced vasodilation. The effect of antibiotic 6734-21 on the viruses of variolovaccine, Herpes simplex, influenza and classical avian plague was studied on various experimental models.

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Withdrawal of differentiation inhibitory activity/leukemia inhibitory factor up-regulates D-type cyclins and cyclin-dependent kinase inhibitors in mouse embryonic stem cells. Optimal space-time coverage and exploration costs in groundwater monitoring networks. Discarded ProFile and ProTaper nickel-titanium rotary instruments, with unknown history of clinical use, were obtained from graduate endodontic clinics at Ohio State University and University of Texas Health Science Center at Houston Dental Branch. A 53-year-old man, who was known to have situs inversus totalis all of his life, had acute myocardial infarction complicated by partial rupture of the posterior papillary muscle causing mitral regurgitation and pulmonary edema.

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Stability of dressed states against radiative decay in strongly coupled bound-continuum transitions. Infectious prion diseases may be acquired, sporadic or inherited in their aetiology. Treatment immediately after injury with each of these agonists resulted in a dose-dependent attenuation of the injury-induced decrease in compound action potential amplitude. Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices.

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Since oxidative damage represents one of the earliest pathological changes in Alzheimer disease, it is likely that aberrant redox activity is among the earliest changes in the transition to the disease state. This novel CaSO4/CaPO4 composite holds promise for clinical applications where a strong, injectable, slower-resorbing, and biocompatible bone graft substitute would be advantageous. These patients showed no other history of exposure to possible transmission routes for blood-borne hepatitis viruses. Loading of glucose in vivo or chronic administration of antidiuretic hormone in vivo did not cause the changes in AC or PDE observed after sodium loading. The genome-associated, specific RNA binding proteins of avian and mammalian type C viruses.

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We aimed to quantify tsunami mortality and compare approaches to mortality assessment in the emergency context in Aceh, Indonesia, where the impact of the 2004 tsunami was greatest. Any patient with an abnormal Papanicolaou smear should undergo colposcopic evaluation.

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We summarize important clinical, pathological and diagnostic features of benign intrascrotal lesions, including paratesticular lesions (adenomatoid tumors, fibrous pseudotumors, cystadenomas, spermatoceles, hydroceles, varicoceles and hernias) and intratesticular lesions (tunica albuginea cysts, testicular simple cysts, epidermoid cysts, cystic ectasia of the rete testis, intratesticular varicocele, adrenal rest tumors and splenogonadal fusion). Primary endpoints-viability and purity-were assessed with the trypan blue viability assay and component counting with a hemocytometer.

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Response of the isolated muscle tissue of frog species to the successive effects of subtoxic and toxic chloral hydrate solutions After functional MRI was performed during the motor task of hand grasp-release movements, the hand motor function was assessed. Decisions to get HIV tested and to accept antiretroviral therapies among gay/bisexual men: implications for secondary prevention efforts.

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Antenatal diagnosis by ultrasound by visualisation of vasa praevia may be difficult by transvaginal sonography alone due to an unfavourable angle of insonation. They were found in several patients autopsied with GM1-gangliosidosis and neuronal ceroid-lipofuscinosis. Molecular and cellular mechanisms of action of angiotensin II (AT1) receptors in vascular smooth muscle. GPR54 desensitization by the high-dose metastin 45-54 infusion was associated with compromised pituitary response to a bolus GnRH injection (0.3 microg). This study is the first to show reduction of active pulmonary vasoconstriction by PGI2 aerosol.

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The Src homology regions 2 and 3, mysterious associates with protein tyrosine kinases Decreased cerebral blood flow (CBF) and cerebral ischemia occurring immediately after subarachnoid hemorrhage (SAH) may be caused by acute microvascular constriction. developed the Defense Style Questionnaire (DSQ), a self-questionnaire that aims at empirically measuring conscious derivatives of defense mechanisms. Temporally linear domain growth in the segregation of binary fluids.

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We found an association between higher hospital volumes and lower rates of mortality and hip dislocation. In three patients, severe adhesions from previous surgeries were removed prior to insertion of the laparoscopic tools. Studies show that under natural conditions trichloroethylene can be anaerobically degraded to dichloroethylene, vinyl chloride, and ethylene. The abnormality of an increased pulsatility index in the superior mesenteric artery velocity waveforms of small-for-gestational-age fetuses suggests greater vascular resistance and an overall reduction in visceral perfusion. Secular trends in time from HIV seroconversion to an NHL diagnosis was estimated using Cox models from data pooled from the 22 seroconverter cohorts in the CASCADE collaboration for three periods (pre-1997, 1997-1998, 1999-2002), adjusting for age at seroconversion, exposure category and sex.

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The aim of the present study was to obtain insight into the reasoning of the caregivers who had reported problems when dealing with older people with dementia and aggressiveness and those who did not relative to their respective video-recorded interactions with these residents. A number of surgical procedures have proved successful in the treatment of stable fractures (e.g. For the smallest masker frequency spacing detection of a high-frequency signal seemed to be improved in the presence of envelope beats, while detection of a low-frequency signal seemed to be degraded by envelope beats. The effect of image processing does not greatly influence diagnostic performance in chest radiography.

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Polymorphic Alu insertions in six Brazilian African-derived populations. Bounds to density-dependent quantities of D-dimensional many-particle systems in position and momentum spaces: Applications to atomic systems. Identifying clinically meaningful improvement in rehabilitation of lower-limb amputees. The erythrocyte composition of the peripheral blood in tobacco smokers Loss of heterozygosity on chromosome 11q23 is observed at high frequency in human nonsmall cell lung carcinomas (NSCLCs), suggesting the presence of a tumor suppressor gene.

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We measured the modulation transfer function (MTF) by using the methods of measuring pre-sampling MTF, and used Fourier transform of image data of the square wave chart. Systemic acquired resistance (SAR) is usually described as a phenomenon whereby localized inoculation with a necrotizing pathogen renders a plant more resistant to subsequent pathogen infection. Unusual benign myxoid nerve sheath lesion: myxoid palisaded encapsulated neuroma (PEN) or nerve sheath myxoma with PEN/PEN-like features? Despite the growing trend toward the use of the in situ bypass, CRI may represent a circumstance where deeply placed grafts should be used preferentially. Serum estradiol (E2) and FSH levels were controlled at the end of the estrogen, placebo, and wash-out periods.