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Patients with chronic heart failure (CHF) are hemodynamically characterized by increased vasoconstriction and a reduced vasodilator response to exercise. Stability of the mutant proteins was determined from thermal-denaturation curves.

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Superficial spreading melanoma arising in a longstanding melanocytic nevus on the sole. These changes were significantly attenuated in the diabetic group treated with ICEI. Improvement in the outcome of rejection with pentoxifylline in renal transplantation: a randomized controlled trial.

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Hypertension and concomitant diseases: a guide for evidence-based therapy. More recent treatment strategies offer patients many options and have increased rates of locoregional control. The chromosomal fragment containing a sequence complementary to the probe appeared to be conserved in B. Microvasculature of the human fetal laryngeal anterior commissure. Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor.

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Here we describe the spatial organization of conserved neutralization epitopes on gp120, using epitope maps in conjunction with the X-ray crystal structure of a ternary complex that includes a gp120 core, CD4 and a neutralizing antibody. Activation of transcription in vitro by recruitment of the yeast RNA polymerase II holoenzyme. Evaluation of CBHP could help identify (in)effective factors and elements of community programmes and thus improve future planning.

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After infection with the early SV40 mutant tsA58, no DNA replication was detected at the restrictive temperature (41 degrees C) and no significant late RNA complementary to the plus (L) strand was found, in either the cytoplasm or nuclei of infected cells. In this study, we used the Porsolt swim test to assess the effects of prenatal cocaine and alcohol exposures on stress-related behavior. Electrophysiological and morphological heterogeneity of neurons in slices of rat suprachiasmatic nucleus.

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HzRV was detected primarily in the Mississippi populations and to a lesser extent in Iowa and Georgia, but none in Maryland, Missouri, and Texas populations. The other embryonic cercaria were selected according to the modified parameter of Chen and Bier (1972). Tolerance to the bronchodilator response of formoterol has not been observed in long term clinical trials.

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Department of Obstetrics and Gynecology, University of Naples, Naples, Italy. To our knowledge, this represents the youngest instance of an isolated lesion of the nail plate without involvement of glabrous skin, caused by C. Intranuclear tubular structures observed in the cells of an alveolar cell carcinoma of the lung.

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Buffering processes in a boreal dissolved organic carbon-rich stream during experimental acidification. Erythropoietin: biochemical characteristics, biologic effects, indications and results of use in hematology In vitro activity of a novel diaminopyrimidine compound, iclaprim, against Chlamydia trachomatis and C. Articular cartilage repair using allogeneic perichondrocyte-seeded biodegradable porous polylactic acid (PLA): a tissue-engineering study. However, little is known about how nicotine might effect cognitive/behavioral inhibition.

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The results supported a receptor model in which the fifth transmembrane domain is alpha-helical, with residues Val197, Ser200, Cys201, and Ser204 exposed in the binding pocket. The nasal epithelial cell profile associated with nasal eosinophilia in asthmatics may differ from that observed in non-asthmatic nasal eosinophilia. The aberration measurement and the corrector control provide instrument alignments stable enough for materials science investigations. External radiotherapy boost was used in one patient not receiving brachytherapy (total dose up to 64.80 Gy).

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Goat V1r-expressing ORNs are categorized into two types situated in different areas of the epithelium. Observation by light microscopy revealed that vacuoles originate in a perinuclear position, increasing in number and size until cell degeneration and lysis occur after 48 h.

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To assess the diagnostic value of the combination of computed tomography and angiography in patients with blunt thoracic trauma and suspicion of aortic injury. Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1. HEADACHES AND THE SIGNIFICANCE OF LYSERGIC ACID DERIVATIVES IN THEIR TREATMENT The higher basal plasma luteinizing hormone concentration in the nephrotic group supports this conclusion.(ABSTRACT TRUNCATED AT 250 WORDS)

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hCG, HPL and PGH) are equally distributed within and between term placentae. The effects of ACTH4-10 versus placebo in the memory of symptomatic geriatric volunteers. The incidence of adverse events and the number of failed extubations were recorded after removal of the ETT. The metabolic syndrome (MS) was defined according to the modified National Cholesterol Education Program (NCEP) ATP III criteria.

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Various psychosocial factors, particularly cancer-related concerns and depression, appear to be related to preoperative and postoperative VEGF level in patients with newly diagnosed colorectal cancer. Occupational exposure to polychlorinated dibenzo-p-dioxins and dibenzofurans in a magnesium production plant. Clinicians should be aware of the frequent and occasionally bizarre complications of CSF shunting.

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The pharmacological actions of gamma-mangostin on 5-HT receptors were also investigated by using contractile response of vascular smooth muscle, platelet aggregation and radioligand binding studies. Prevalence of bands other than 160 and 130 kDa in pemphigus sera (a multicenter immunoblotting study). Metacercariae isolated from cyprinoid fishes in Khon Kaen District by digestion technic.

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Gantry tilt scanning was performed to avoid artifacts from dental structures and transverse images reconstructed from oblique images by gantry tilt scanning using a technique of multiplanar reconstruction (MPR) . It is suggested that the above syndromes be regarded as early unspecific signs of development of vibronoise pathology during the early stages of its development.

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In most natural allopolyploids harboring a relatively balanced ratio of homeologs, one homeolog was expressed preferentially, but in the majority of plants, low levels of transcription could be detected from the other homeolog. This technique has the potential to become a viable option for fistula-in-ano surgery. In addition, for 4 of the 5 noncovalent structures we found a docking within 2 A RMS of the experimental structure within the top 20 dockings as ranked by energy. V-src kinase shifts the cadherin-based cell adhesion from the strong to the weak state and beta catenin is not required for the shift.

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The evidence does not support advising patients that epidural labor analgesia increases the risk of cesarean delivery. Array-Comparative Genomic Hybridization (aCGH) is a powerful high throughput technology for detecting chromosomal copy number aberrations (CNAs) in cancer, aiming at identifying related critical genes from the affected genomic regions.

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Cardiovascular evaluation in Turner syndrome: utility of MR imaging. Conservation and covariance in PH domain sequences: physicochemical profile and information theoretical analysis of XLA-causing mutations in the Btk PH domain.

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8-Arylflavones were obtained from commercially available chrysin via two different synthetic pathways. In contrast, inhibitory vagal inputs or superfusion with citrate, an inhibitory metabolic modifier, revert preexisting expiratory-inspiratory discharges into a phase-coupled inspiratory pattern. Relationship between dietary fatty acid, selenium, and degenerative cardiomyopathy. Further study is needed in larger populations to confirm these findings, and if confirmed, to determine the reasons that patients fail to achieve lipid goals.

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A chromatin immunoprecipitation assay combined with real-time PCR analysis was used to analyze protein-DNA interactions at approximately 500-bp intervals across the first 60,000 bp of the EBV genome. A study of condylar movement by bilateral simultaneous videofluorography. Unexpectedly, melanocyte stem cells independent of the c-Kit signal were maintained in the skin of the SLF transgenic mice. The MAb reacted with single, paired, and Maltese cross forms of B.

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Cytogenetic analysis of a human embryonal rhabdomyosarcoma revealed a near-diploid karyotype with structural chromosome aberrations not involving the typical rearrangements of rhabdomyosarcomas, plus a large number of double minutes. It is also recognised that reducing inappropriate FFP usage will play a role in improved patient safety. The first step of the lipase-catalyzed hydrolysis of insoluble long chain triglycerides is the adsorption of the enzyme to the interface. Presence of PCV DNA was detected in cells and supernatant by PCR, expression of viral proteins by an indirect immune fluorescence assay.

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The polarized situation between Th1 and Th2 cells is established to be important in animal models and human autoimmune diseases. Collection and storage of leukocyte depleted whole blood in autologous blood predeposit in elective surgery programs. A constituent of the unsaponifiable portion of animal tissue lipids (lambda max.

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Each wound was rated for level of injury and was mapped according to the location of the wound on the body. This study aims to evaluate the dose dependent effect of nicotine on bone regeneration using a rabbit model of mandibular distraction osteogenesis.

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Type 2 diabetes in children and adolescents: screening, diagnosis, and management. Formal analysis of alternative strategies and well-designed clinical studies are needed before an optimal policy for caring for mothers and infants can be identified. In a study of the aetiopathogenesis of primary hyperlipoproteinaemias, which has not yet been elucidated, we paid attention to the heparin-activated lipolytic enzymes. Effects of androgen administration in men with the AIDS wasting syndrome. However, the physiological role of takeout and its putative link to JH remain unknown.

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Penicillium marneffei is a thermally dimorphic opportunistic human pathogen with a saprophytic filamentous hyphal form at 25 degrees C and a pathogenic unicellular yeast form at 37 degrees C. Infection of PCV1 was observed with 293, Hela and Chang liver cells, infection with PCV2 only in Rd cells. Habituation-like decrements in transmission along the normal and lesion-induced temporodentate pathways in the rat. Taken together, these data demonstrate that nitric oxide is an important mediator of acetaminophen-induced hepatotoxicity. Serotonin (5-HT1A-receptor) agonist-induced collecting duct vacuolation and renal papillary necrosis in the rat.

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In terms of efficacy the holmium laser procedures appear to be similarly effective to TURP in relieving the symptoms of benign prostatic hyperplasia. Type-1 long-QT syndrome (LQTS) is caused by loss-of-function mutations in the KCNQ1-encoded I(Ks) cardiac potassium channel. Cyclosporin A selectively reduces the functional expression of Kir2.1 potassium channels in Xenopus oocytes.

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The ADM (Aide au diagnostic Medical) project was started 15 years ago and was the first telematic project for physicians in France using the MINITEL terminal. 12-month-old animals were decreased, including superoxide dismutase (SOD), catalase, and glutathione reductase (GSSG-Rd). High positivity of anti-BPI antibodies were seen even among the youngest CF patients, before the development of clinical signs of CF, indicating that formation of ANCA might be a very early event in the disease.

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It was not possible to determine a pattern of severity of EIPH in horses with more than one endoscopy. Column separation of viral capsid antigen (VCA)-positive cells from VCA-negative cells in an Epstein-Barr virus (EBV)-producing lymphoid line,.

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Characterization of unmyelinated axons uniting epidermal and dermal immune cells in primate and murine skin. The molecular structures of both domains have recently been elucidated. The first objective of this study was to evaluate the hypothesis that cholinergic projections to the SCN are only present in nocturnal species.

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Plasma renin and angiotensin II concentration increases were dose-dependent. TLR2-mediated survival of Staphylococcus aureus in macrophages: a novel bacterial strategy against host innate immunity. We have previously shown that the type I IFN IFN alpha induces the expression of the cyclin-dependent kinase inhibitor p21WAF1 and inhibits the cell cycle of the human prostate adenocarcinoma cell line, DU145, that carries mutations in the tumor suppressor gene products p53 and pRB.

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The value of peritoneal cytology in the staging of ovarian cancer To differentiate, over a 5-year period, non-compliant (NC) from compliant (C) consumers of psychotropic drugs according to their demographic characteristics and views on: their faith in the prescriber, the effects of consumption, opinion of family and friends and information received. All mutations could be confirmed by restriction enzyme digestion of PCR amplicons.

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Responses of atropinized or plexus-free muscle to electrical stimulation were also not potentiated by PGE1. Biotransformation of acrolein in rat: excretion of mercapturic acids after inhalation and intraperitoneal injection. Fibroblastic cells from rat skin and lung did not accumulate triglycerides when exposed to VLDL and heparin. Post-kala-azar dermal leishmaniasis is a dermatosis which was described during the first quarter of this century.

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Eosinophilia was observed in peripheral blood and in the cerebrospinal fluid. We examined whether the T102C polymorphism of the serotonin receptor 2A gene (HTR2A) moderated the influence of childhood or adolescence parental socioeconomic status (SES) on adulthood temperament trait harm avoidance (HA) in a population-based sample of 1246 healthy Finnish men and women, who were 24-39 years of age in the last follow-up phase.

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Longitudinal analyses support the idea that methamphetamine is used by gay men to mask feelings of discomfort and to enhance sensations as well as sexual pleasure. Its product (previously termed transmembrane protein 76, or TMEM76) has little sequence similarity to other proteins of known function, although it is well conserved among all species. Activity of Escherichia coli DNA-glycosylases on DNA damaged by methylating and ethylating agents and influence of 3-substituted adenine derivatives. We demonstrate that Ep-CAM expression is targeted to the lateral domain of epithelial cells of the human fetal pancreas, and that it mediates calcium-independent cell-cell adhesion. This functional property elicits the oncogenic activation of chimeric proteins arising from translocation of the SAM domain of TEL to coding regions of the betaPDGF receptor, Abl, JAK2 protein kinase and the AML1 transcription factor.

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Suture-ligation of the bleeding site delayed healing when compared with simple compression. significantly lower for patients treated on-demand compared with either of the general practitioner-controlled intermittent treatment strategies. Treating MCD diet-fed mice with DGAT2 ASO for 4 and 8 weeks decreased hepatic steatosis, but increased hepatic free fatty acids, cytochrome P4502E1, markers of lipid peroxidation/oxidant stress, lobular necroinflammation, and fibrosis. Dysphagia caused by ossification of the anterior longitudinal ligament associated with diffuse idiopathic skeletal hyperostosis: report of 2 cases Manual volumetry confirms that preterm infants at term-equivalent age have reduced thalamic and lentiform volumes compared with controls.

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Poly(A)-binding-protein-mediated regulation of hDcp2 decapping in vitro. In the observational phase, each participant served protocol-specific meals and snacks at predetermined times. This was accompanied by the inhibition of nuclear NF-kappaB binding activity and NF-kappaB transcriptional activation. By using magnetic resonance imaging, we analyzed the position of the femoral head in 21 hips of 21 infants with developmental dislocation.

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Collateralization and the response to obstruction of epicardial coronary arteries. Antibody titers gradually decreased after inoculation and rose from PID 21 or 28 and were between 1:160 and 1:640 on PID 63. Voltametric investigations showed a significant effect of pH on electrochemically measured cadmium content in the culture media.

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Our results show that this sub-domain dimerizes at very high concentration but is neither required for yeast viability, nor for incorporation of two TAF(II)5 molecules within TFIID and for the assembly of this complex. An evaluation of the effects of renal artery stenting in renovascular hypertension. Results are presented which illustrate the behaviour of a lamprey out of water. The tumor in case 2 was incidentally found at laparoscopic cholecystectomy.

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This study was designed to find a group of affected patients and study their clinical characteristics and immunologic responses to Histoplasma antigens. Oral dosing of rats with OM-89 results in the appearance of specific OM-89 antibodies of the IgG2a isotype: possible significance in the treatment of rheumatoid arthritis. To study the effect of sumatriptan, an agonist of enteric neuronal 5HT1p receptors, on interdigestive motility in man.

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