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High-performance liquid chromatography-fluorescence assay of pyruvic acid to determine cysteine conjugate beta-lyase activity: application to S-1,2-dichlorovinyl-L-cysteine and S-2-benzothiazolyl-L-cysteine. CXCR4 is required by a nonprimate lentivirus: heterologous expression of feline immunodeficiency virus in human, rodent, and feline cells. affect, rules, and goals inferred about an interpersonal situation) than concrete cues (i.e. Although the basic morphological patterns observed in the layers constituting the cyst walls were similar in all species examined, the thickness of each layer was apparently different.

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CCK-, secretin-, and cholinergic-independent pancreatic fluid hypersecretion in protease inhibitor-treated rats. Unmethylated CpG oligodeoxynucleotides (CpG ODNs) activate immune responses in a TLR9-dependent manner. This case highlights the need for routine electron microscopy in native renal biopsies, where the differential diagnosis is wide and varied and the light and immunofluorescence microscopic findings may be non specific. Bradykinin-mediated metabolic effects in isolated perfused rat hearts.

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Detection of depolarization-induced coated vesicles within presynaptic terminals in cat sympathetic ganglia maintained under a low temperature. Lymphocyte counts returned to preinfection levels in the blood of animals which recovered, but death from theileriosis was characteristically accompanied by a persistent and severe lymphocytopenia.

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Available evidence suggests that outcomes, including pain severity, general health and functional status, and disability are more significantly improved after this approach than after isolated medical or surgical interventions. Effects of chronic exercise on blood pressure in Dahl salt-sensitive rats. The physician should distinguish between excessive gas (which indicates excessive gas production) and feelings of bloating (which are usually unrelated to excessive gas production). In contrast, virus binding to alphavbeta6 including the beta8 cytodomain (alphavbeta6/8) was lower than that of the wild-type integrin, and this binding did not lead to infection. Limited progress has been made in understanding the pathophysiologic mechanism involved in the interaction.

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Human prostate carcinoma cells (PC3, DU145, LNCaP), colon cancer cells (HT29) and human microvascular endothelial cells (HMEC-1) were transfected in vitro with constitutively driven CMV/iNOS or hOC/iNOS plasmid DNA by cationic lipid vector. Toluene vapor produced robust, concentration-dependent, discriminative stimulus effects, with concentrations of 4000 ppm and higher producing full substitution. pHi was significantly higher during ECC with hypothermia (T1) than at baseline (T0).

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The phosphorylated protein found in extracts of these human interferon-treated hybrid cells was of mouse origin. To our knowledge, this is the first time that this phenomenon has been reported. These experiments show that seminal plasma can elicit expression of a range of inflammatory cytokines and chemokines in reproductive tract epithelia, and implicate the ectocervix as the primary site of responsiveness, with gene-specific differences in the kinetics and site-restrictedness of the response.

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Suplatast tosilate can inhibit IL-4 production and suppress IgE synthesis in vitro. Attenuation of influenza A virus mRNA levels by promoter mutations. The radial forearm flap has proved to be a reliable free flap for intraoral reconstruction after major head and neck ablative surgery for cancer.

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Some previously published data concerning the spatial distributions of dendritic spines are re-examined. Hypercytokinemia is suspected to be the underlying mechanism for the clinical and laboratory findings in patients with FEL, although the relationship to the vascular pathology is unclear. Favorable functional results can be achieved by IOL implantation in children with cataracts.

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The authors illustrate the case of a young asymptomatic patient with constantly high levels of CPK, who was later affected by Central Core Disease (CCD), a rare hereditary slow progressing myopathy strictly related to MH. Sexual dimorphism in the mouse hypothalamic-pituitary-adrenal axis function after endotoxin and insulin stresses during development. However, comparison with age-matched controls showed that, even 24 months post-lesion, the density of 5-HT innervation remained abnormally low. Characteristics of novel monofilament sutures prepared by conjugate spinning. A descriptive correlational survey was conducted and data were collected by using a structured questionnaire.

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This case illustrates the need to think of inherited thrombophilia as a primary cause. A review of the literature indicates that nine well-documented cases of extrarenal Wilms tumor have previously been described. These findings indicate that gravitropic curvature is not necessarily permanent, and that the root retains some commitment to its equilibrium orientation prior to gravitropic stimulation. Further study revealed that JNK was activated and that NF-kappa B was inhibited in Nox4/P22 cotransfected osteoclasts. Pulsed-field-gradient NMR techniques are demonstrated for measurements of time-dependent gas diffusion.

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The inductors-solenoids are fixed tangentially on the chest by means of the jacket. Postural reactions were quantified by measuring electromyographic activity of the triceps surae and anterior tibialis muscles. Tumorlets tended to be multiple and bilateral but were absent in 9 patients with multifocal disease, including 4 of 10 with bilateral tumors. Patients completed questionnaires pre-operatively to record expenses during the previous three months and health status immediately prior to surgery.

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Cystic metastatic intracerebral neuroblastoma has not been described. The osmo- and galofility is inherent in all the investigated strains. Although microorganisms are degrading the contaminants in bioremediation processes, soil animals can also have important--while usually an indirect--role in these processes. Effects of simulated acid rain on growth rate in a spruce-living spider. Pathogenetically, docetaxel may evoke a lupus-like eruption through its proapoptotic effects on replicating cells, which could in turn provoke the release of nucleosomes postulated to be target antigens in LE.

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Results were analysed in relation to the concentration of LH and prolactin in the peripheral circulation. All CD patients who received at least 8 doses of infliximab at the University of Pittsburgh infusion center were included in an analysis to determine the need for dose intensification. Following the recent mapping of CD40 to chromosome 20q we sought to determine its position relative to 20q deletions. A similar, acquired condition is occasionally seen, associated with malignancies or as an autoimmune process.

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In addition to the 19 reported and characterized aflatoxin pathway genes and the four sugar utilization genes in this cluster, we report here the identification of six newly identified genes which are putatively involved in aflatoxin formation. Study of the effect of cAMP on the mitotic regimen in the esophageal epithelium of tumor-bearing mice Pharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. The clinical, histopathological, immunochemical, and immunocytochemical features of leiomyomas (LM) and leiomyosarcomas (LMS) were investigated by a panel of monoclonal antibodies specific for some differentiation markers of SM tissue (SM myosin and alpha-actin, desmin, and SM22) and for markers of non-muscle tissue (vimentin and non-muscle myosin). Site-directed mutagenesis was used to examine the role of domain II, loop 2 residues, 368RRPFNIGI375, of Bacillus thuringiensis insecticidal protein CryIAb.

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The method consists of adsorbing the viruses to silicon dioxide (SiO2) in the presence of 0.5 mM AlCl3 and adjustment of the pH to 3.5. Increased culture confluence impairs migration and is related to an upregulation of TIMP-3. Intrathecal injection of either 10 nmol of calcitonin gene-related peptide 8-37 or 26.6 nmol of morphine induced significant bilateral increases in hindpaw withdrawal latency, which were more pronounced with the morphine. Inflight SAS, perceptual illusions, and ocular changes are of more importance. Allergenic plant and pollen atlases for pollen characteristics, allergy texts for procedures and overviews, and relevant reviews from the English medical literature (1985 to present).

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With these changes the ureter is in line with the camera and we may have a good access to the pelvis, making the distal dissection of the ureter easier. These clinical aspects are underlain by complex cellular mecanisms which are essentially located inside the conjunctiva.

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Distinguishing this from a true hypopyon is important because the treatment and prognosis are very different for the two conditions. We conclude that iodothyronines, glucocorticoids, and GH act directly on human hepatocytes to regulate the expression of CYP3A4, and these effects appear to be exerted at a pretranslational level. Transformation of skin fibroblast cells of a cystinotic patient by simian virus 40: evidence for an establishment of a permanent cell clone which retains the original metabolism defect.

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There was significant visual improvement with pleoptic treatment in one amblyopic hypermetropic patient. The effect of Serum Thymic Factor (FTS) on neuromuscular transmission has been studied in vivo by electromyographic assay. This tRNA(Tyr) was unable to suppress the UAG codon, indicating that nucleotide modifications in the anticodon of tRNA(Tyr) have either stimulating (i.e., psi 35) or inhibitory (i.e., Q34) effects on suppressor activity.

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Several new molecules are being studied in the treatment of the COPD, for which the fight for the final suspension of the tobacco use is one of the determining elements. In the present investigation, computational and experimental methods were employed to address a number of fundamental issues related to the representation and structural organization of spoken words in the mental lexicon and to lay the groundwork for a model of spoken word recognition. Effect of cholesterol on the formation of micellar complexes between bovine A-I apolipoprotein and L-alpha-dimyristoylphosphatidylcholine. Anterior pituitary cells defective in the cell-autonomous factor, df, undergo cell lineage specification but not expansion.

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Acetylsalicylic acid inhibits monocyte adhesion to endothelial cells by an antioxidative mechanism. Influence of bladder contractility on short-term outcomes of high-power potassium-titanyl-phosphate photoselective vaporization of the prostate. Photosensitivity lasting less than 24 h and nausea coinciding with peak skin PpIX fluorescence occurred at 20 and 40 mg/kg doses. A model for the structure of the P domains in the subtilisin-like prohormone convertases. Although the differences in FFE separation of the endocytic compartments as seen in HRP uptake were striking, the minor changes seen within the lysosomal system were more subtle, as depicted in the protease profiles.

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Inactivation of p53 in a human ovarian cancer cell line increases the sensitivity to paclitaxel by inducing G2/M arrest and apoptosis. While it has long been documented that nicotine contained in tobacco leaves gives rise to major public health problems it has also been observed that this alkaloid can have beneficial effects.

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A 46-year-old patient presented with adult onset discoloration of the dentition following prolonged minocycline therapy. Des-gamma-carboxyprothrombin (PIVKA II) and plasma vitamin K1 in newborns and their mothers.

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The bacterial gene ubiC encodes chorismate pyruvate-lyase, an enzyme which converts chorismate to 4-hydroxybenzoate and which is not normally present in plants. Second, we demonstrate that the induction of DSBs or chromosome-type aberrations by AraC in human lymphocytes is inhibited by cycloheximide (CHM), an inhibitor of protein synthesis. Chimpanzees were more sensitive to the concave deformation than to the convex deformation. These strains share unique amino acid residues at positions 222A, 256I, and 294I, which are not present in other less virulent strains. Studies were conducted to characterize 18 isolates of Campylobacter spp.

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Large round granular dense bodies of an unknown nature can be observed inside and outside the nucleus. Wear fragments were seen as irregularly shaped flakes, splinters and polyhedral structures ranging from 1 to 100 microns in size.

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She presented approximately 24 h post-ingestion with a serum APAP level of 130 micrograms/ml. These data indicate that gliclazide, aside from either a direct antioxidant action or an effect on insulin or glucose levels, may ameliorate diabetic endothelial cell dysfunction. DNA immunization induces systemic humoral and cellular immune responses to the antigen encoded by cDNA in a plasmid DNA.

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Mechanism of rapid-phase insulin response to elevation of portal glucose concentration. Portal pressure indices are not however used routinely as predictors of survival. TESTICULAR DYSGENESIS WITH INTERSEXUAL EXTERNAL GENITALIA AND MALE CHROMOSOMAL PATTERN OF 46/XY

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Gomortega appears to have no embryological autapomorphies, but further comparison with Atherospermataceae is required. The addition of the single-phase genotyping step avoids the need for the re-amplification and cloning of PCR products, while providing its own controls for the detection of contamination and allelic drop-out.

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Improper use of natural resources and short-term economic objectives have resulted in severe environmental degradation in a fairly short time frame and the degradation has now reached a level where the health and well being of the coastal populations are threatened. Post-transcriptional regulation of the Brn-3b transcription factor in differentiating neuroblastoma cells. Prophages (45-60 kbp) are integrated in the bacterial chromosome, and they are UV- or mitomycin-inducible. Gomez-Lopez-Hernandez syndrome is a very rare genetic disorder with a distinct phenotype (OMIM 601853).

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This paper describes the utility of the theory of mental economics (Freud, 1900) in explaining the phenomena that occur in the functional and organic psychoses. No plaque morphology or temperature sensitive mutants were selected for in the NJ culture, and we were unable to detect the presence of either a defective or defective interfering virus population. Recent advances in research methods and technologies have resulted in an explosion of information and knowledge about cancers and their treatment. Medical artwork was used to aid the reporting of circumcision status. Cutaneous melanoma: a population-based epidemiology report with 989 patients in Hong Kong.

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The mean-squared displacement correlation with time lag had slopes with values of unity for simple HA solutions and for synovial fluid from an individual who genetically lacked lubricin, in contrast to slopes with values less than unity (alpha approximately 0.6) for normal synovial fluid. On admission, the animal was unconscious and remained so for 2 days. African blacks account for the majority of the reported SMA cases. The main integrin receptor in the mesangium is the alpha 1 beta 1 integrin. Although LTA4 hydrolase, a final-step key enzyme to produce LTB4, is located in glomerular mesangial cells, as well as in leukocytes, platelets, and endothelial cells, its precise distribution in the kidney other than in mesangial cells remains unknown.

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This paper briefly reviews the changing epidemiology of dengue, discusses some of the factors responsible for the recent resurgence, and reviews the current options for reversing the trend of emergent disease. Direct class-II composite restorations demonstrated extensive microleakage at their dentin cavosurface margins. Enterosgel was used in 89 patients with different stages of renal failure treated surgically and medically. In addition, strategies for successful implementation of IIPs were outlined.

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In fast motor units, the maximal contractile output increased with potentiation and was reduced with fatigue, and the optimal frequency decreased and increased, respectively. To find out the impact of hepatic diseases on care activity at national and autonomous region level, and in a tertiary hospital with a Hepatology Department. Recently, it was hypothesized that acute or cumulative suppression of non-REM sleep intensity might be related to the therapeutic effects of antidepressants.

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The developed triple column EOP was incorporated within a micro-fluidic chip (5.0 x 2.0 x 0.4 cm) integrated with a second single 10 x 0.1 mm column EOP, for combined sample injection and simple on-chip micro-flow analysis. The receptor of the virus is localised on endothelial cells and that could explain purpuric lesions and ulcerations observed. This report illustrates that genitofemoral neuralgia can result from laparoscopic inguinal herniorrhaphy and offers a management strategy for this pain syndrome. Radio-telemetric recordings in a sublethal model showed that the nonsurvivors remained hemodynamically stable until approximately 1 h before death, when heart rate and blood pressure fell rapidly. 35S-rhINV(1-585) is also cross-linked to form a high-molecular-weight product.

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Although these bodies are not viral elements, it is surmised that they may be virus associated and consequently possibly related to the etiology of this tumor. Use of a simulator with CT option in radiotherapy of macular degeneration. Muscimol-stimulated Cl(-)conductance in synaptoneurosomes returned to normal 48 h after pentylenetetrazole administration.

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Pneumoviruses, which are viruses of the family Paramyxoviridae, subfamily Pneumovirinae, are pathogens that infect the respiratory tract of their host species. Sequencing analysis led to the identification of three mutations: a transversion C-to-A creating a stop codon (Y98X), an A insertion at position 460 (460insA), and a C deletion (1114delC).