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The use of both state-of-the-art and emerging glycosylation technologies has led to significant advances in this field, allowing the clinical exploration of carbohydrate-based antigens in the treatment of cancer. Survival of premenopausal women with breast carcinoma: effects of menstrual timing of surgery. Both isoforms of S100 interact with intact caldesmon and its C-terminal deletion mutant 606C (residues 606-756) with apparent Kd of 0.2-0.6 microM thus indicating that the S100-binding site is located in the C-terminal domain of caldesmon.

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These results provide strong evidence for the influence of the male on gene transcription in the female and contribute a molecular basis for the classical histological observation that the maturation of females is male dependent. In contrast, we found that within the hippocampus delta/theta power alternated in parallel with fast oscillations above 16 Hz during non-rapid-eye-movement sleep (positive correlations). A tumor in the paracolpium is very rare and generally only discovered by chance.

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These differences were considered to be accounted for by the high blood pressure and the structural change of arterial wall in the hypertensive patients. Recordings of GiA cells, initially using minimal surgery, revealed that many had low levels of spontaneous activity and responded vigorously to noxious stimuli applied to any part of the body surface. A single oral 20 mg/kg dose of ibuprofen was administered, and blood samples were obtained at 15, 30, 45, 60, 120, 240, and 360 minutes after the dose was administered. Beginning with the theoretical premise that pain stimuli are liable to perturb the ordinary dynamical state of the brain, we hypothesized that individuals in pain may experience impaired information processing. The effects of formoterol, a long-acting beta 2-adrenoceptor agonist, on mucociliary activity.

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Tele-ophthalmology consultations were carried out with three ophthalmologists working in a specialist eye clinic in Townsville, 900 km away. Longitudinal data from the New Hope Project--an experimental evaluation of a work-based antipoverty program in Milwaukee, Wisconsin--was used to explore concurrent and lagged associations of nonstandard schedules and variable shifts with parental psychological well-being, regularity of family mealtimes, and child well-being among low-income families. Pairs of active sites are linked through a flexible polypeptide loop which probably mediates the structural changes giving rise to cooperative effects. The magnitude of the fixed separation distance may explain how chromosome segregation is kept in close register with cell growth and the initiation mass for DNA replication.

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The effects of the different diets on weight, the ratio of fat to body weight and free fatty acids were observed. Measurement of select transition strengths and autoionizing lifetimes in atomic oxygen.

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The level of physical growth and development, function of immune system, intelligence were chosen as the health-response indexes of children. No improvement of liver histology was observed in any of the treated patients. Elicitation and inhibition of competitive fighting in food deprived mice. Computations on metric maps in mammals: getting oriented and choosing a multi-destination route.

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Once inside the cell, the porphyrin ring of heme is degraded by heme degrading monooxygenases, leading to the formation of free iron for use by the bacterium as a nutrient source. Autonomic nervous system activity and ascorbic acid content in the blood plasma.

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In one case 56 days after infection herpesvirus-like particles were observed by electron microscopy in the tumorous gonads and liver. Information regarding the response of brain cells to infection with herpes simplex virus (HSV)-1 is needed for a complete understanding of viral neuropathogenesis. Many viruses, including coronaviruses, induce host translational shutoff, while maintaining synthesis of their own gene products. S-100 protein was localized in granular cells of adult GCT but not in the granular cells of congenital epulis. A synthetic peptide corresponding to amino acids 9-30 of the extracellular domain of the follitropin (FSH) receptor specifically binds FSH.

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The transphenoidal approach to the pituitary gland is emerging as the safest and most efficacious procedure for the management of pituitary tumors. Modulation of drug metabolizing enzymes in guinea pig liver by high intakes of ascorbic acid. HNF-3 protein activates while p53 represses AFP transcription through sequence-specific binding within the previously identified AFP developmental repressor domain. In animals and humans, inhibition of nitric oxide (NO) production has widespread effects.

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The same processes that produce sex differences can also produce individual differences among males. Our purpose was to present information about open surgical biopsy. Actin polymerization was assessed by measuring F-actin content using NBD phallacidin staining and fluorescence activated cell scanner analysis.

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It is considered to be a product of a duplicated complement component C4 gene, but without functional activity. Reduction in muscle mass (sarcopenic obesity) is an important determinant of physical function and metabolic rate. Microalbuminuria (MA) is a strong predictor of cardiovascular disease, but its causes are incompletely understood. ON HYGIENIC CONDITIONS OF THE SEACOAST OF SARDINIA BETWEEN CAPE TEULADA AND CAPE ALTANO Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from isolated peripheral blood mononuclear cells.

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The aim of this study was to examine the trend of hospitalisation amongst the elderly in urban China and analyse the main socio-economic factors which are affecting the use of inpatient care. TI90 did not affect VD3 metabolism or the number and affinity of VD3 receptors (VDR) in HL-60 cells. Dysphagia in the second or third decade of life may suggest eosinophilic esophagitis.

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We formulate a two-phase paradigm of autoimmunity associated with systemic lupus erythematosus, the archetypal autoimmune disease. The patients were divided into three categories according to the characteristics of the cyst (calcified, alive and dead cyst). Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. She presented with a palpable abdominal mass, multiple bezoars in the bowel, and paper excretion in the feces before admitting intentional ingestion of toilet-paper balls. The family physician must be involved in the follow-up of ambulatory surgery

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In vivo transient assays of the site directed mutant promoters using firefly luciferase as a reporter showed that an AT-rich sequence, ACAAATA, in the GC-rich promoter sequence is not required for transcription. Evaluation of a hospital-based community liaison pharmacy service in Northern Ireland.

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On the other hand TNF-alpha had a similar effect only when given intraperitoneally but not by peroral route. Controlled clinical comparison of Isolator and BACTEC 9240 Aerobic/F resin bottle for detection of bloodstream infections. The two patients with long-term follow-up (56-60 mo) have remained clinically stable without evidence of local or distant recurrence. In the absence of steroids or in the presence of 17beta estradiol, or a combination of 17beta estradiol and progesterone, SP inhibited the GnRH-induced LH release.

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While CL was significantly higher in subjects with periodontitis, there was no difference in hydrogen peroxide production between the patients and the controls, indicating that the hyperreactivity is related to the generation of other oxygen species than H2O2 and/or to processes in the outer cell membrane. A role for natural killer cells in the immunopathogenesis of multiple sclerosis. Chromobacterium violaceum presents a distinctive phenotypic characteristic, the production of a deep violet pigment named violacein. Finishing diamonds are preferred for gross finishing of adjusted porcelain. (b) To examine assault/event characteristics, personal, parental, and environmental factors associated with the retaliatory attitudes of adolescents who have been assaulted.

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The characteristics of kidney involvement in a female patient with systemic lupus erythematosus and the antiphospholipid syndrome This paper presents a mathematical model for the learning of accurate human arm movements. Testosterone (T) as a compound for treatment of T deficiency has been available for almost 70 years, but the pharmaceutical formulations have been less than ideal. Young and older adults demonstrated comparable abilities in the use of contextual information in each modality, but older adults, regardless of hearing status, had more difficulty with fast presentation of auditory speech stimuli than young adults.

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Transposon mutagenesis and subcloning of one of the selected genome fragments have led to the identification of three enzymatic activities: a monooxygenase activity encoded by a 3-kb PstI-EcoRI fragment and an epoxystyrene isomerase activity and an epoxystyrene reductase activity encoded by a 2.3-kb BamHI fragment. To present the results of a multi-institutional prospective study of speech and swallowing function before and after soft tissue reconstruction of the oral cavity and oropharynx, and to compare 3 methods of reconstruction with respect to speech and swallowing function: primary closure, distal myocutaneous flap, and microvascular free flap. Heightened awareness of being overweight may enhance the provision of weight reduction care. The present possibilities of the therapy of type 2 diabetes are presented.

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Angiosarcoma involving the gastrointestinal tract: a series of primary and metastatic cases. Remarkably, we found that p60-specific Th1 clones mediate significant protection against L.

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On the basis of clinical, easily discovered, signs the essential differential diagnosis and specific diagnostic techniques (electromyography, electroneurography, angiography, computotumography) and their indications are outlined. The cuffed oropharyngeal airway, a novel adjunct to the management of difficult airways. The findings appear to indicate that the prevalence of allergic contact dermatitis is higher in older patients and that contact dermatitis tends to occur on the extremities in older patients than younger patients. This brief review is devoted to the histopathological characterization of 2 such sclerosing lesions of the breast: radial scars and sclerosing nipple adenomas. Analysis of variation in mouse TPMT genotype, expression and activity.

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Dome-shaped gold nanoparticles (with an average diameter of 10.5 nm) are grown on H-terminated Si(100) substrates by simple techniques involving electro- and electroless deposition from a 0.05 mM AuCl3 and 0.1 M NaClO4 solution. Outcomes for patients undergoing one or more total hip and knee arthroplasties. After surgical and/or conservative treatment, 28 patients (pts) with GBM underwent FDG and MET PET on average 12.7 months after the diagnosis had been established.

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MRI was performed and radiographs were obtained with six-month intervals from the time of diagnosis up to two years in nine hips (eight patients). A baculovirus mutant defective in PKIP, a protein which interacts with a virus-encoded protein kinase. This inhibition is reversible if the compound is applied in the dark but becomes irreversible after irradiation with white light.

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Many trace elements act as antioxidants or are able not only to regulate the host immune response but also to alter the viral genome. In this study 22 different protein constructs, with different characteristics regarding pI and solubility, were successfully purified by the laboratory robot. Antiepidermal growth factor receptor has shown promising antitumor activity in nonsmall cell lung cancer patients with a mild toxicity profile. Mesenchyme cells from Mf1lacZ embryos differentiate poorly into cartilage in micromass culture and do not respond to added BMP2 and TGFbeta1. Furthermore, MRS imaging may prove to be a useful tool for studying the response to medical treatment and the pathophysiologic basis of epilepsy.

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In this study, 101 patients with mild essential hypertension were randomly assigned to an 8-week period of monotherapy with enalapril 10 mg a day or indapamide 2.5 mg a day. All these microcirculatory parameters significantly increased after nifedipine treatment while both systolic and diastolic pressures decreased. We first characterized the functional cytoarchitecture of an organotypic co-culture model of rat dorsal root ganglia and spinal cord.

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This implies that RA stimulates proliferation differently than other hyperplasiogens, and hence may induce irritation and growth stimulation through another mechanism. Tuberous sclerosis complex (TSC) is often associated with intractable epilepsy.

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The prefrontal cortex and working memory: physiology and brain imaging. This is a tribute to the success of the Burma Trachoma Control Program and demonstrates the need for such a program to remain an integral part of public health care and community health services to further diminish the prevalence of this condition. Recently, early application of nasal mask ventilation (NPPV) on patients with TB seq has prohibited acute exacerbation of chronic respiratory failure. The membrane-spanning domains of SCAP and HMG-CoA reductase confer sterol sensitivity upon the functional activities of the two molecules.

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40 speech-anxious subjects were asked to deliver four speeches during the experiment. In addition, c-fos response to acute cocaine administration, in contrast to wild-type mice, is absent in D2R-/- mutants. The transforming DNA integrates into the plastid genome by homologous recombination via plastid targeting sequences. Cardiac troponin I (cTnI) measured after heart surgery has been associated with operative mortality. This high-throughput method has the advantage that it directly measures cyclooxygenase activity and requires little enzyme.

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In contrast, the CD4-binding domain is thought to induce neutralizing antibodies that are group specific and capable of neutralizing all isolates of HIV-1. These results point to a model in which lipid molecules located on the transmembrane surface of a membrane protein (the annular lipid molecules), by playing a dominant role in the interaction between a membrane protein and the surrounding lipid bilayer, could effectively buffer the membrane protein from changes in the properties of the bulk lipid bilayer. The purpose of this study was to investigate how the heart rate and diurnal heart rate pattern change when dogs become pregnant or lactate.

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TGF-beta isoforms and gangliosides were found to differentially stimulate HGF production by these cells. Updates in Pediatric Urology: Highlights of the American Academy of Pediatrics Section on Urology Annual Meeting, October 7-9, 2006, Atlanta, GA.

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The results are discussed in the context of prohibitin interactions with mitochondrial AAA-proteases and we suggest two possible interaction interfaces between the BAP32:BAP37 building block and the protease. The radiologic and pathologic features of this cerebellar lesion are reviewed, including the newly reported presence of vascular contrast enhancement within the mass. In coculture, these heterologous cells communicate by means of gap junctions.

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The association constants and the numbers of binding sites for both subtypes were determined as a function of ionic strength. In conclusion, DHA-As tended to suppress the reperfusion-induced arrhythmias in rat hearts. Osteoporosis is often cited as a contraindication for pedicle screw fixation. Double excitation of helium by electron impact: A distorted-wave polarized-orbital approach.