Miodar is used to treat and prevent certain types of serious, life-threatening ventricular arrhythmias (a certain type of abnormal heart rhythm when other medications did not help or could not be tolerated. Miodar is in a class of medications called antiarrhythmics. It works by relaxing overactive heart muscles.

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The recent identification of numerous skeletal muscle proteins and of the codifying genes made possible a new classification of a large group of muscular dystrophies. Retinal capillaries showed marked changes: localized narrowing, constriction, bead-like features, caliber irregularity and occlusion. A number of 3-keto bile acids were synthesized by the selective oxidation of bile acid methyl esters with silver carbonate-Celite in refluxing toluene. These findings suggest that central nonunion may be associated with delayed expression of osteoblast related genes in the central region of the forming fusion mass. Treatment of unresectable stage III non-small-cell lung carcinomas

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The middle and lower lobes were resected and lymph node dissection was performed. Appropriate gastric resection with lymph node dissection for early gastric cancer. No statistically significant differences were found between the patients with schizophrenia and the control patients without neuropsychiatric disease for the densities of any of the markers, while both groups exhibited fewer lesions than did the control group with Alzheimer disease. To investigate the effect of commercial race training on right ventricular (RV) and tricuspid valve function in an untrained group of National Hunt Thoroughbreds (TB).

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US and UK versions of the EQ-5D preference weights: does choice of preference weights make a difference? Further study is necessary to evaluate the real benefit of this surgical procedure over the functional outcome of ICH. Therefore, it is an ideal candidate for making inferences about the mean response in a log-regression model. Effect of process variables on the microcapsule size distribution. The expressed EGFP was extractable from cocoons through a simple procedure with neutral pH buffer solution.

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Photoisomerization efficiency in UV-absorbing visual pigments: protein-directed isomerization of an unprotonated retinal Schiff base. The computational results have further been used to analyze the spectra measured in methanol and to explain the remarkable red shift of one CD band when trifluoroethanol is used as a solvent instead of methanol. Furthermore attempts were made to define the influence of factors important in experimental and water respect.

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Drugs are divided into 6 classes, according to their action on: 1) signal-transduction systems, 2) other components of plasmatic membranes, 3) intracellularly, 4) gene therapy, 5) extracellularly, 6) invasive agents. This article addresses the clinical issues relevant to mental health workers when evaluating children of diverse cultures who live in conditions of persistent poverty. An initial experiment was conducted to test the utility of a monocular switch procedure as a method of rapidly introducing a visual perturbation. A long stenosis beginning at the origin of the artery predisposes to restenosis, but repeat dilatation often produces lasting benefit.

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This chapter depicts three different approaches for the use of biocatalysts in production processes: non-chiral synthesis, asymmetric synthesis, and racemic and dynamic resolution. Alpha-1-antitrypsin deficiency with pulmonary emphysema, cirrhosis of the liver and cholangiocarcinoma

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Arthroscopic-assisted lateral ligamentous reconstruction in combined ankle and subtalar instability. WT may be detected by its attenuated ultrasound pattern versus a non-attenuated pattern for RT by IVUS. Our analysis suggests that these structural elements might also contribute to rejection of other mischarged aa-tRNAs formed in vivo that are not involved in peptide elongation. The yield of each of the two products strongly depends on the reaction conditions employed.

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The pregnancy rates and outcomes in the three groups were compared. Scanning electron microscopy showed that adhesion between coatings and the titanium substrate was close.

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The findings also suggest that remoxipride may have a therapeutic effect on negative symptoms of schizophrenia. The strategy for molecular analysis was to amplify the coding regions of the long wavelength-sensitive (L) and middle wavelength-sensitive (M) cone opsin genes and the upstream locus control region by polymerase chain reaction, and to examine these fragments for mutations by direct sequencing. Ciliary neurotrophic factor (CNTF) and glial cell-line-derived neurotrophic factor (GDNF) at a high concentration, yielded statistically significant improvements in rat outer segment survival times. Alpha2C(AS) infusions did not reduce the ability of UK14,304 to inhibit forskolin-stimulated cAMP accumulation.

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It is concluded that disturbances in blood flow and TcPO2 occur early in diabetes, and are consequences of poor glycemic control. Interestingly, activation of PKA abrogates the inhibitory effect of Rab13 on the recruitment of vasodilator-stimulated phosphoprotein, ZO-1, and claudin1 to cell-cell junctions. One to three weeks after a complete transection of the spinal cord at a low thoracic level, rats were given either intrathecal injections of serotonin (5 mM, 15 microL) or intraperitoneal injections of quipazine (400-600 microg/kg). Strong-potential Born-approximation electron-capture cross sections for realistic atomic potentials.

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Nicotinamide adenine dinucleotide-specific glutamate dehydrogenase of Neurospora. The use of SPECT-CT allowed exact localisation of the lymph node fragments in three-dimensional space and the regeneration of the lymph node fragments was documented histologically. Direct head or orofacial injury was therefore not a prognostic indicator.

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Effective single-particle potential for photoabsorption of open-shell atoms. Simulated titrations of magnetic susceptibility show a sensitivity to the model chosen indicating the usefulness of future experiments in this area. The sensitivity to the inhibition by synthetic capsaicins remarkably differed between NDH-1 and NDH-2, supporting the notion that the sensitivity against capsaicin inhibition correlates well with the presence of an energy coupling site in the enzyme (Yagi, T. Using this method, it is possible to treat opacities that eventually might occur at the level of the visual axis on the optic faces of polymethylmethacrylate intraocular lenses (IOLs) if safety parameters (perfect focusing, use of additional lenses, and slight and continuous movement of the focal point of the laser) are followed. Liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry applications with methanol gradients.

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In thoracic aortic pseudoaneurysm repair, a temporary bypass between the right axillary artery and left external iliac artery was generally adopted. Addis Ababa Tuberculosis Demonstration and Training Center, Ethiopia. Prolonged use of this drug, however, has been associated with the subsequent development of AML and, up to November 1987, 16 cases of acute leukemia following razoxane treatment have been reported.

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Midpoint potentials of plant-type ferredoxins from a range of sources were measured by redox titrations combined with electron-paramagnetic-resonance spectroscopy. MRI can be helpful in identifying the lipomatous nature of the mass, but the findings can be inconsistent due to variable maturity of fat cells and the mesenchymal content of the tumor. The fluoride concentration in the drinking water of towns in the Transvaal, Orange Free State and Natal. It is argued here that although there is reason to doubt that data subjected only to NHST have been subjected to sufficient analysis, the search for clear answers to well-formulated questions derived from substantive hypotheses is well served by NHST.

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To gain insight into cadherin-2 role in the formation of these structures, we have used several markers to analyze zebrafish embryos injected with a specific cadherin-2 antisense morpholino oligonucleotide (cdh2MO). Degradation of the matrix was observed between the chondrocytic columns accompanied by degeneration and disappearance of chondrocytes. Evaluation of 50-mer oligonucleotide arrays for detecting microbial populations in environmental samples. Eye movements and target fixation during dragonfly prey-interception flights.

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She had varices at the terminal ileum and adhesion between the ovary and the ileum end. the tumor decreased 1.5-3 times after 12 daily injections of lysates from 15 million epimastigotes. We are reporting a patient with a relatively large pineoblastoma, who was treated with a combination of nonresective treatment modalities.

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For those few polyps that cannot be endoscopically managed, laparoscopic techniques provide a safe and attractive option. Differences in pathogenicity and antigenicity among hog cholera virus strains. It is concluded that this type of nephroblastoma, resembling a renal adenocarcinoma, should be borne in mind with a view to an optimal postoperative treatment. As a consequence infarction of the head of the caudate nucleus without neurological compromise was observed on follow-up CT scans.

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Validated portable pediatric vision screening in the Alaska Bush. Healthcare profiles: similarities and differences with respect to case and disease management The aim of the study was to investigate the orocecal transit time (OCTT) and the presence of small intestinal bacterial overgrowth (SIBO). All patients were treated with GKR without severe adverse effects, and all but 1 patient received subsequent chemotherapy shortly after GKR.

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The approximate molecular weight of the activator was estimated as 400,000 by gel filtration. Investigation of the mitochondrial genome in patients with atypical motor neuron disease. These observations suggest that these tissue types are defective in their capability for bioactivation of DCE.

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Transverse twist flap for lip reconstruction in patient with lentigo maligna of the labial mucosa. Information model of systemic organization of human mental functions: new approach to the problem of artificial intelligence

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Cell therapeutic technologies of a new generation: preconditions and problems of realization Our results show that the Net TCF is part of the biological response to hypoxia, adding a new component to an important pathological and physiological process. Major adjustments in the technique included: transfixing of the peritoneum with 4 stay sutures prior to opening, suturing the peritoneum to the seromuscular coat of the colon, eversion of the end of the colon and joining of adjacent skin to the rim of the colon. Hypoxanthine, xanthine, guanine, xanthosine, guanosine and adenosine are ineffective. The mere introduction of the project might have led to other changes affecting dental caries, such as improved oral hygiene and better dietary habits.

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In this article, we identify the binding sites in the P1 and P2 promoter regions of c-myc for the intercalating antibiotics actinomycin D and elsamicin A. aeruginosa infection led to an inverse correlation between lung function parameters and levels of IgG3 and IgG4. Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro. Most research facilities have developed training programs to meet these requirements but may not have developed ways of assessing the effectiveness of these programs.

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Abnormal distribution of Fc gamma receptor type IIa polymorphisms in Korean patients with systemic lupus erythematosus. Inflammation is a recognized risk factor for the vulnerable atherosclerotic plaque. We report a case of spontaneous multivessel coronary vasospasm leading to anterior myocardial infarction and cardiogenic shock in the setting of treatment with methylphenidate and withdrawal from beta-blockers and calcium channel-antagonists.

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Adaptive mechanisms of the noradrenergic cyclic AMP generating system in the limbic forebrain of the rat: adaptation to persistent changes in the availability of norepinephrine (NE). Whether these manifestations are anatomically circumscribed or widespread will depend upon the route by which autonomic infection is acquired as well as the character of interaction between the virus and the infected autonomic neuron. Role of cholinergic mechanisms of the ventrolateral preoptico-anterior hypothalamic area in regulation of sleep and wakefulness states in pigeons A cytological study of the lysogenization of Shigella dysenteriae with P1 and P2 bacteriophages. Withdrawal symptom severity was assessed on a daily basis by means of the Short Opiate Withdrawal Scale.

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Variation in the guanylate kinase isozymes was detected in a small population of orangutans. This indicated that the distribution of antiviral IgG antibodies in serum and CSF normally follows the distribution of total IgG.

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We used both the direct capillary and indirect agarose dropiet methods and, as the source of antigens, viable tumor cells and 3 M KCl-solubilized extracts. epidermidis showed increases of up to 64 times the original MIC. Household expenditure on confectionery was associated with caries only among children from the manual group. Rayleigh matches were measured before and after 30 min adaptation to monochromatic light of 520, 550, 580 or 620 nm. Based on available data, the new European guidelines for the management of bleeding in the trauma patient do deliver a number of sound recommendations.

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In this observation in the community setting, a strategy of primary angioplasty in patients with high-risk myocardial infarction was not better than thrombolysis in terms of mortality or recurrent infarction, but was associated with less angina at 1 year. 50 patients (43 men) were randomly allocated treatment with subcutaneous rhGH (2 IU daily) or placebo for a minimum of 12 weeks. In order to clarify the mechanism of mesangial cell dysfunction in diabetes, we examined the activities of protein kinase C (PKC) and mitogen-activated protein kinase (MAPK), important kinases in various cellular functions, and also evaluated the isoenzymes of PKC in mesangial cells cultured under high glucose conditions. Persistent cloaca is only rarely associated with UPIIIA mutation. Degradation of poly(lactic-co-glycolic acid) microspheres: effect of copolymer composition.

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The protocol includes the following procedures: collecting and developmentally staging Drosophila pupae, dissecting fly eyes at defined stages of development, immunostaining of retina and preparing visual system samples (i.e., retina and optic lobe) for confocal microscopy. Intracellular growth hormone has been demonstrated in human mammary carcinoma cells by using an unlabeled antibody enzyme technic with horseradish peroxidase and antihorseradish peroxidase complex. Due to the uniformity of the search, the optimality of the statistics, and the exponential increase of the splitting frequency of the niches, OMOEA uses a deterministic search without blindness or stochasticity. We prospectively obtained 124 samples of urine from 122 children younger than 1 year of age for routine clinical indications from the emergency department at Yale-New Haven Hospital.

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The voxel projection algorithm does not suffer from artifacts associated with the nearest neighbor algorithm. It is often clinically noted that peripheral nerve transections in infants and very young children seem to show better functional recovery after nerve repair compared with adult patients. Researchers create genetically modified bugs to fight malaria, Chagas, and other diseases.

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Of the enzymes involved in triglyceride synthesis from fatty acid in lipid micelle membranes, only acyl-CoA synthetase was inhibited by calcium ion, the apparent Ki value of calcium ion being 4.2 X 10(-4) M. Multivariate logistic regression for familial aggregation in age at disease onset.

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Toll-like receptor 2 (TLR2) contributes to host response in pneumococcal meningitis by enhancing bacterial clearing and downmodulating inflammation. Implications for structure and function of tetanus toxin receptors and potential pathophysiological significance. A comparative study of pre-operative procedures to assess cervical invasion by endometrial carcinoma. Since the neuropeptide Ang II is able to repress PN-1 synthesis in cultured Schwann cells, loss of neuronal contact might decrease their responsiveness to Ang II, thus resulting in PN-1 up-regulation by default. Histopathological changes in rat pancreas after fasting and cassava feeding.

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It is therefore possible to grow the wires in two steps: to fabricate an axial heterostructure (at 420 degrees C), and then cover it by a shell (at 390 degrees C). The changes in atrial volume in response to a given pressure load are also more pronounced in the absence of calcium or following the addition of the calcium blocker.

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The protocol is for the in-gel digestion of both silver and Coomassie-stained protein spots or bands and can be followed by MALDI-MS or LC-MS/MS analysis to identify proteins at sensitivities better than a few femtomoles of protein starting material. We examined this phenomenon in a sample of 291 trios for five genes previously associated with ADHD (HTR1B, SNAP-25, DRD5, DAT1, and BDNF).