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Transmission in the pathway of reciprocal Ia inhibition to motoneurones and its control during the tonic stretch reflex. We have cloned and analysed the sequence of a putative histidine kinase, two-component gene (CaHK1) from Candida albicans. Role of human liver lipogenesis and reesterification in triglycerides secretion and in FFA reesterification.

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Ligand binding also changes the conformation of the ligand binding domain (LBD), allowing interaction with coregulators via LxxLL motifs. AFF-1 ectopic expression results in fusion of cells that normally do not fuse in C. A PTH/PTHrP receptor N terminus modified by deletion of the nonhomologous E2 domain transferred weak PTHrP interaction to the PTH2 receptor.

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A very curious type of asthenia or the therapeutic avatars of an undetected bilharzia They found that ablation of the GGTase-I-encoding gene in cells destined to produce lung tumors driven by oncogenic K-Ras resulted in delayed onset and decreased severity of disease, validating in a genetic model the theory that GGTase-I is a good target for anti-cancer drug development.

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Carbohydrate metabolism abnormalities are a major aggravating risk factor in cirrhosis. They were confirmed post mortem by histology and immunohistology. Prognostic value of human telomerase reverse transcriptase gene expression in oral carcinogenesis. These results indicate that the fidelity of nucleolar readouts is controlled by regulatory proteins of the nucleolar chromatin.

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Exact tests of associated hypotheses and unbiased estimates of genotype effects were from an animal model. This was due to the presence of more resistant lymphoid cells and activation of lymphocytopoiesis proper. MNS16A has been investigated as a potential risk factor and/or prognostic marker for malignant glioma in a cohort of 352 patients (205 glioblastoma, 147 anaplastic gliomas) and 305 controls. Periodic and turbulent behavior of solitary structures in distributed active media.

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Stimulus-dependent oscillatory activity in the lateral geniculate body of the cat. In posthemorrhagic patients, the cortisol/insulin index drastically elevated and remained high within 14 days. In a subsequent experiment IBV was recovered from the caecal lymph nodes and faeces of one of five birds 14 weeks after infection with a commercial vaccine but no virus was isolated from the trachea, kidneys, duodenum, bursa, ovaries or testes of any of the five birds at this time. The preclinical evidence for a potential influence of calcium channel blockers (CCBs) on carcinogenesis is discussed in the light of a broad database from rodent carcinogenicity studies as well as literature data.

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It is hypothesized that these stress effects on the course and outcome of psoriasis are caused by neuroendocrine modulation of immune functions. The economic burden of complications during percutaneous coronary intervention. Planned preventative maintenance (PPM), quality control (QC) checks and breakdown all contribute to the down-time of a radiotherapy treatment machine. Of 84 specimens requested for anti-Ro antibody, 76 were collected and tested with the EUROLINE test kits and eight were excluded due to inadequacy. Comparative studies between the non-fibrin-selective streptokinase and fibrin-selective recombinant t-PA (rt-PA) have shown a difference in efficacy for early coronary artery recanalization, whereas the GUSTO trial has established that clinical benefit in patients with acute myocardial infarction is indeed correlated with the rapidity and frequency of sustained recanalization and that effective thrombolysis requires adequate anticoagulation.(ABSTRACT TRUNCATED AT 250 WORDS)

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Severe craniofacial injury may cause intractable oronasal bleeding, which is refractory to conventional treatments. Three auxiliary proteins of apparent molecular masses of 18, 38 and 43 kDa are invariably associated with the nine tRNA synthetase components of the complex. Increased serum N-acetyl-beta-D-glucosaminidase and alpha-D-mannosidase activities in obese subjects. The congenital tumors are similar in location and pathology to astrocytomas of the cord in older children. Extensive studies for infectious causes of diarrhea were negative, and no patient responded to antibiotic therapy.

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Within three months of treatment, we found that HGV RNA was transiently cleared in 6/7 patients, but the rate of long-term favorable response was very low (1/7). In addition, the most common diseases (such as cancer, coronary heart disease, dementia, diabetes mellitus, hypertension and osteoporosis), the drugs usually prescribed to treat them, and the adverse nutritional reactions that occur in older patients are summarized. A case-control study was conducted on groups of lambs from 122 Western Australian sheep flocks. Here we show that while myeloma cells secrete IgA2m(2) predominantly as H(2)L(2), CHO cells secrete H(2)L and H(2) in addition to fully assembled H(2)L(2). Resolution of the Ba (6pjndj)1 and (6pjndj)3 autoionizing states and their mixing with the (6pjns1/2)1 and (6pjngj)3 states.

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Splenic sympathetic response to endotoxin is blunted in the fetal alcohol-exposed rat: role of nitric oxide. Fresh produce is the major source of vitamin C in the human diet yet only limited information is available concerning its route(s) of synthesis in plants.

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The effects of several inflammatory mediators on the patency of the Eustachian tube were evaluated in 15 mongrel dogs. In both developing and industrialised countries the use of safe and simple procedures for appropriate periods, particular attention to drug prescription patterns and selection of appropriate aims and modes of therapy, including non-invasive methods, may minimise the risks of paediatric intensive care. Genetic studies suggest that WIGGUM acts on a similar process but in a separate pathway than the CLAVATA1 and CLAVATA3 genes in meristem size regulation, and reveal interactions with other genes affecting meristem structure and identity. The highly metastatic MDA-MB-435 cells express substantial levels of this receptor, whereas MDA-MB-231 and MCF-7 cells do not.

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To identify the causes of acute headache presenting to the emergency department (ED), assess the adequacy of history, examination, and investigation, and determine which clinical features are predictive of secondary headache. Intra-articular bupivacaine plus adrenaline for arthroscopic surgery of the knee.

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Metastases can develop later from what appears primarily a benign, as well as a malignant, type. Synthetic peptide ISCOM vaccines are few because of the difficulty in incorporation of these peptides into ISCOMs. Methodological problems of prospective natural trials are discussed. HB-EGF transcripts were detected in RNA isolated from 15 of the 22 tissues obtained from adult pigs, which is consistent with the ability of diphtheria toxin to affect many body tissues.

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The pH of the dissolution medium and the flow rate were related to the in vitro dissolution rate. Seventeen of these 20 patients developed the full pattern of severe myoclonic epilepsy in infancy (SMEI). There was a statistically significant loss of p75NTR immunopositive fine nerve fibres in the epidermis of lesional psoriatic skin and a statistically significant loss of p75NTR immunopositive fine nerve fibres in the dermis in both non-lesional and lesional psoriatic skin. We show that SUMO-1 modification appears to be dependant on the correct subcellular compartmentalisation of target proteins.

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A single exercise session did not alter the plasma lipoprotein or vitamin E status. Salinomycin (SAL), an ionophorous polyether antibiotic with growth promoter properties in pigs, has proved to be effective in controlling swine dysentery, porcine intestinal adenomatosis, and porcine haemorrhagic enteropathy. The determination of relationships among and the identification of potyviruses with polyclonal antibodies does not always lead to a proper conclusion.

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Efavirenz induces a striking and generalized increase of HDL-cholesterol in HIV-infected patients. The commonly used catecholamines: receptor and clinical profile, indications and dosages.

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AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis. Muscle fiber formation requires the sequential expression of myogenic regulatory factors (MRFs) such as MyoD and myogenin. The development of asymmetric Morita-Baylis-Hillman (MBH) reactions has evolved dramatically over the past few years, parallel to the emerging concept of bifunctional organocatalysis. Degradation of collagen also results in peptide fragments of various lengths which are excreted in the urine.

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Two mutations have been found in this gene that are potential markers for haemochromatosis. Three LD5 antibodies raised against rabbits showed cross-reaction. The advantage of measuring spontaneous growth hormone (GH) secretion compared with the insulin tolerance test in the diagnosis of GH deficiency in young adults. Expression of mucin antigens in human cancers and its relationship with malignancy potential.

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This review describes these varied aspects of GABAA receptor research with special emphasis on contemporary cellular and molecular discoveries. We found that the mutated p53 gene correlated with increased resistance to DNA-damaging agents but the sensitivity to anti-microtubule agents was independent of the mutation, suggesting a clinical significance of the status of p53 gene in astrocytic tumours and a rational application of anti-microtubule agents to the patients with p53-mutated astrocytic tumours. Greater standardization in the reporting of review methods may assist with future efforts to summarize studies of the relationship between physical environments and physical activity. The test involved ethanol fixation of microcultures of bovine rotavirus-infected BSC-1 cells and reacetion with bovine antirotavirus serum, followed by 125I-labeled rabbit anti-bovine immunoglobulin G.

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Ocular responses to horizontal table velocity steps in darkness exhibited a direction-specific asymmetry in UVN rats. Serum angiotensin converting enzyme (ACE) activity in sarcoidosis

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The article outlines types of water migration in the absence of gravity. These enzymes represent a superfamily of hydrolases which are likely to have arisen by divergent evolution. A graded diagnostic scale permits detection of a category of subsyndromal delirium which occurs in many ICU patients, and which is associated with adverse outcome. Preservation of mitochondrial volume homeostasis at the early stages of age-related synaptic deterioration.

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Due to the lack of studies with long-term follow up, it is unclear whether these effects are stable after stopping propranolol. This decreased conversion rate results in decreasing the length of operation time and postoperative and total hospital stay.

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They recommend that ultrasound screening should be carried out by an orthopaedist in order to further shorten diagnosis and treatment times. Alendronate treatment maintained all parameters of bone turnover at control (nonovariectomized) levels and prevented the bone loss in a dose-dependent manner. A number of the new therapeutic agents marketed in 2003 have important advantages over older medications. Because Ito is markedly prolonged at low temperatures it is suggested that it can be responsible for the early repolarization wave (J wave) observed in the ECG of subjects submitted to hypothermia. The sensitivity of the models to their various parameters is examined.

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Under the Food, Drug, and Cosmetic Act, efficacy must be demonstrated by evidence consisting of adequate and well-controlled investigations to show that a drug is safe and effective for its intended use. Postoperative administration of TPN supplemented with Gln and rhGH in patients after portal hypertension surgery improves immune function, modulates inflammatory response, prevents the intestinal mucous membrane from atrophy and preserves intestinal integrity.

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Fibreoptic bronchoscopy showed marked diffuse mucosal thickening with highly conspicuous vascular plexuses. The experiment further demonstrated that the VV sinus expands rapidly against back pressure, a critical character to consider in venous prosthesis design. It is suggested that a condition in Australian lambs characterised by hairiness of the birth coat and poor viability is due to foetal infection with a mucosal disease virus.

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Juxtagonadal mesonephric glomeruli in fetuses of 11 to 21 weeks of gestation. Private practice, Vernon, British Columbia, Canada, and scanning electron microscope laboratory, Mastel Precision, Rapid City, South Dakota, USA. After stimulation of epidermal hyperplasia, MT-null and normal mice showed significantly reduced levels of zinc.

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To perform a retrospective review of laryngeal/hypopharyngeal carcinomas treated with concurrent chemotherapy and intensity-modulated radiotherapy (IMRT). Findings in vivo of Sarcoptes scabiei with incident light microscopy.

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Semi-structured interviews were conducted with these respondents as well as with 30 veterinarians, 27 extension officers and 19 animal health assistants/agricultural officers, and the 7 key respondents that they identified. Localization of tyrosine-phosphorylated proteins in cultured mouse dorsal root ganglion neurons. Imperfect pitchfork bifurcation with weak noise and an application to superfluid turbulence in liquid helium. An increase of procoagulant activity was demonstrated for bags A and C.

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Thirty healthy subjects (15 smokers and 15 nonsmokers) of both sexes were studied. G protein-coupled receptors (GPCRs) constitute a large superfamily involved in various types of signal transduction pathways, and play an important role in coordinating the activation and migration of leukocytes to sites of infection and inflammation.

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Preradiotherapy (pre-RT) and postradiotherapy (post-RT) MR sialographic images of the major salivary ducts (parotid and submandibular) were compared. Thus, Bfl-1/A1 transduction could be an interesting tool to obtain myeloma cell lines from primary samples and to favour the in vitro generation of antibody-secreting, long-lived normal PC. pylori infection and the ulcer stage were investigated by endoscopy every 6 months. This signaling pathway may be crucial for the control of B-cell differentiation and antibody response and has implications for the regulation of other POZ/zinc finger transcription factors in other tissues. The U-shaped metal device was used in place of the Velcro straps or ear bars routinely used for frame positioning in which the distance from the frame base to the top of the head must always be measured to avoid collisions with the localizer box.

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Electroacoustic admittance was measured around the resonance frequency of a 27 MHz quartz resonator in parallel with microbalance measurements. Interferon gamma immunotherapy for generalized verrucosis in the setting of chronic immunodeficiency. Lysosomal storage diseases (LSDs) are monogenic disorders of metabolism caused by deficiency of hydrolytic enzymes. The results were compared with similar anaylses performed on juvenile and adult human pancreases before and after islet isolation and on intact and dispersed neonatal rat and adult rat pancreas. Immunoblot and immunocytochemical analyses showed that neither the precursor nor the mature form of the PPCA gene product was present in the cultured cells.

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Siderophore-mediated iron uptake in Saccharomyces cerevisiae: the SIT1 gene encodes a ferrioxamine B permease that belongs to the major facilitator superfamily. The use of hydrocortisone suspension in nasal allergic and infectious conditions. The first of the three articles in this series (1) expounded the case for a broader approach to research design in nursing. Only the fetal common carotid artery has constant pulsatility and resistance indices during gestation.

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The problem is non-linear, but the algorithm is algebraic and does not require initial parameter estimates. MH susceptibility (MHS) is assessed by pharmacological tests performed on muscle strips. Pet-keeping in early childhood and airway, nose and skin symptoms later in life. Impact of immunosuppression caused by HIV infection on the replication of hepatitis C virus.