Nexe reduces the amount of acid your stomach makes.

It's used for heartburn, acid reflux and gastro-oesophageal reflux disease (GORD) - GORD is when you keep getting acid reflux. It's also taken to prevent and treat stomach ulcers.

Sometimes, Nexe is taken for a rare illness caused by a tumour in the pancreas or gut called Zollinger-Ellison syndrome.

Nexe also comes mixed with naproxen, a medicine that reduces inflammation and pain in joints and muscles.

Nexe comes as capsules, tablets, granules and as a liquid.

All types of Nexe are available on prescription. You can also buy the lowest-strength 20mg tablets and capsules from pharmacies.

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Oxytocin is believed to attenuate the response of the hypothalamic-pituitary-adrenal axis to stress and to be anxiolytic. Compliance with the chemoprophylaxis among our inmates is inadequate although it matches similar studies that have been carried out on the prison population. Proteinase inhibitor 6 cannot be secreted, which suggests it is a new type of cellular serpin. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The CST provides a nondestructive and efficient means of identifying and isolating E cells from mixed populations.

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Although the dimensional analysis method for solving dose calculation problems is gaining acceptance with nurse educators, many inconsistencies in teaching methodologies remain that can be confusing to both students and practicing nurses. We performed a retrospective review of 161 patients who underwent hysterectomy for uterine leiomyoma between January 1994 and December 1994 and between July 1995 and April 1996. We investigated the role of human CRM1 (hCRM1) (exportin 1) in the function of Rex protein encoded by human T-cell leukemia virus type 1.

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The optimisation of a synthetic strategy towards the ABC segment of the cytotoxic macrolide spirastrellolide A is reported, together with its application to the synthesis of two diastereomeric C(1)-C(22) fragments for stereochemical correlation purposes with a putative spirastrellolide degradation product. This contrasts with the normal blood picture, where most gamma delta T cells express V delta 2 conformational epitopes.

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Effects of luteinizing hormone-releasing hormone agonist on bladder carcinogenesis in male rats This article provides an overview of the general approach to fever in the returned traveller, including identification of common causes and management. Estrogen could greatly improve activities of GG and stimulate the expression of ERalpha. A large number of respondents selected the worst or a poor treatment option for the chronic pain vignettes.

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Photograft polymerization of SS-Na was verified by further reduction of fluorine atomic content and the appearance of new sulfur and sodium atomic peaks on ESCA survey spectra, and that of PEG-Ac was verified by further reduction of fluorine atomic content and increase of atomic percent ratio of O/C from ESCA survey spectra as well as appearance of a new ester peak on high resolution ESCA C 1s spectra. Relevant publications usually use the scientific method, appropriate control groups, blinded reading, prospective design, and other study elements. The following variables were measured: helping, empathy, altruism, morality, attribution of responsibility, cognitive readiness to help, willingness to help, social desirability, and abstract thinking.

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Although its application in this field is just at an incipient stage, the use of MIPs in the design of new drug delivery systems (DDS) and devices useful in closely related fields, such as diagnostic sensors, is receiving increasing attention. In addition, changes in employment, disability status, productivity, and hours worked per week of patients in clinical remission and patients not in clinical remission were compared.

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The influence of temperature (20-85 degrees C) on the functional properties of native and UV modified SOD has been studied. Buccolingual and mesiodistal diameters were determined on the teeth of 202 Paraguayan Lengua Indians, 100 skeletal Blacks, 206 living South African Blacks and 125 living South African caucasoids. Moreover, the lack of TG staining in typical apoptotic bodies may account for a perturbation of the cross-linked apoptotic envelope that may be an important determinant in the development of immune response in ulcerative colitis.

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These tissues give reliable and sensitive indications of industrial pollution in the forest ecosystems. Many case-control association studies have been performed to see if BDNF could serve as a useful clinical diagnostic biomarker for schizophrenia or bipolar disorder, but results have been equivocal.

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The ability of tetrapeptides, but not tripeptide vinyl sulfones, to act as substrates for the proteasome suggests there could be a minimal length requirement for hydrolysis by the proteasome. Syndromic surveillance for measleslike illnesses in a managed care setting. We used a two-stage procedure (screening and clinical interviews) and the same procedure was repeated after a 1-year follow-up. This function can be very helpful in determining patient separation and posterior source-to-skin distance (SSD) and also in the setting up of abutting and preplanned ports. This study was undertaken to investigate the relation between dietary fat composition and adiposity in adult men.

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As lung injury occurred, tidal volume increased and airway pressure waveform changed. The removal of N-alkylpurines was similar in the active MT I gene region in Cdr200T1 and the silent MT I gene region in the parental cells, and the expression of these genes was determined by Northern assay. The clinical features of each of the three type 2 infections are described in detail. We described the hepatic dysfunction found in 10 cases out of 32 women with typhoid fever during pregnancy.

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Early onset sarcoidosis is a granulomatous disease which is characterized by synovitis, polyarthritis, skin and eye involvement. The results of these studies are eagerly awaited and it is anticipated that epothilones may become an important treatment option in patients with breast cancer. Further studies are to be carried out in order to identify more accurately this link and to extend the study to other fungi. The 5-HT-containing neuronal terminals of the brain stem hypothetically mediate the cortisol level decrease after levodopa intake because these cells contain an important fraction of amino acid decarboxylase.

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Gel analysis of the fertile donor proteome maps revealed excellent reproducibility as well as very low intra-donor and inter-donor variability in the presence of protein spots. The aim of this article is to explain the current status of deinstitutionalisation and of community care development in the UK. This technique is well suited to unilateral and bilateral combinations of obturator, inguinal, and femoral hernias. Amongst other regulatory elements, Puckered, a Drosophila MAPK phosphatase, is involved in a negative feedback loop that controls JNK signaling activity. Computational analysis of the available crystal structures of redox protein complexes reveals features of the binding site that favor fast dissociation.

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To evaluate a new method for rapid and efficient assessment of capillary morphology. The proportion of patients needing dose increases to maintain cyclosporine trough levels within the desired range was significantly higher in the Sandimmune group during the first 3 months of the study, whereas the number of patients needing dose reductions was similar in both groups throughout the study period.

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Orthopoxvirus DNA: strain differentiation by electrophoresis of restriction endonuclease fragmented virion DNA. Following genotoxic stress, p53 occupancy increased whereas DeltaNp63alpha occupancy decreased at the majority of binding sites examined. Critics and proposals aimed to a reform of the system are discussed. This study demonstrates a wide range of normal coronary sinus ostium diameters, morphology, and anatomic relationships with surrounding structures, with no demonstrable correlation to the presence or absence of dual AV node physiology or AV nodal reentrant tachycardia. As they aged, men and women gained less weight in proportion to their levels of sustained vigorous activity.

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During the early phase of infection, few but significant and reproducible differences were observed. In 25 internal carotid artery stenoses, reduction of the intrastenotic lumen contrasted by blood density signals and color Doppler signals on longitudinal and transverse views was assessed for correlative evaluation. All animals demonstrated adhesions between the posterior and lateral surfaces of the heart and pericardium. A case of renal cell carcinoma with lung metastasis and local recurrence effectively treated with nephrectomy and UFT

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Abnormal distribution of O-alkyl groups in the neutral glycerolipids from human hepatocellular carcinomas. Eight rats were trained to press a bar on a second-order schedule of reinforcement and tested in the presence and absence of the second-order stimulus. Microglial cells, the resident phagocytes of the central nervous system (CNS), are hematopoietic-derived myeloid cells and express the triggering receptor expressed on myeloid cells 2 (TREM2), an innate immune receptor. The sub-epithelial band-like collagenous deposit may be the result of fibroblastic production with autoimmune stimulation.

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Subjectively, those treated with ACTH gel were pleased with the results and reported more favourably on the injections than those receiving placebo. Both epitope mapping and other in vitro selection techniques produce short polypeptides that tightly and specifically bind to any of a wide range of macromolecular targets.

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The current experiments demonstrate that compilation of a simple noun phrase (NP) yields word class effects in picture-word interference experiments in the same time frame as that generally observed for semantic processing. Enhancement of muscle regeneration in the rat gastrocnemius muscle by low energy laser irradiation. Hemangiomas and hemangiosarcomas are rare, naturally developing tumors of blood vessels. To examine the relationship between depression and psychosocial functioning up to 5 years after traumatic brain injury (TBI).

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The porins-mediated increase in interleukin transcripts did not require de novo protein synthesis, and it was because of the enhanced half-life of IL-1 and IL-6 mRNAs, rather an increased rate of gene transcription. Ethics of placebo-controlled trials of zidovudine to prevent the perinatal transmission of HIV in the Third World. However, only at the lower concentration chromate net uptake was rapidly replaced by net efflux presumably due to toxic effects. Evidence suggests that UVB-induced immunosuppression is mediated in part by immunosuppressive and immunoregulatory cytokines. It is suggested that such nonlinear responses of the phase transformations may arise from synergistic effects of bond instability, localized excitations, enhanced diffusivity, or thermal equilibrium in reactions.

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Cutaneous side effects associated with interferon-alpha therapy: a review. There is no evidence for the development of tolerance with this schedule, which allows for a 17-hour nitrate withdrawal period. The results demonstrate the utility of LLNA data for interpretation in the context of quantitative structure-activity relationships, the limited number of variables, inter-test reproducibility and quantitative end point, lending themselves to mathematical interpretations. A randomized, double-blind, placebo-controlled, dose-ranging study of dofetilide in patients with inducible sustained ventricular tachyarrhythmias.

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Determination of the maternal mortality ratio and the main causes of maternal death. Tumor size and palpable tumor remain unquestionable factors of bad prognosis. This study focuses on the injury rates for natural grass and AstroTurf surfaces and the risk factors of game position and type of play.

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Histologic examination of the eyelid lesion revealed an angiofibroma, which was an unusual initial site of involvement in tuberous sclerosis. The weight increase was significantly larger in the group of corneas exposed to 5.0 mg/ml as compared to 3.0 mg/ml.

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An unusual manifestation of osteo-articular, tendinous and nervous involvement secondary to tophaceous gout of the hand. The purpose of this study was to learn how women experiencing preterm labor come to know a health deviation exists, and what they do when faced with such a problem. The patterns of plasma concentrations of hGH, ACTH, LH and FSH during gestation indicate a maximum of secretion at mid-gestation followed by a progressive decrease of these concentrations until term.

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The class I and class II antigens resemble their mammalian counterparts in the encoded protein structure. Polymyalgia rheumatica preceding small-vessel vasculitis: changed spots or misdiagnosis? To effectively address the persisting problem of social exclusion of persons with psychiatric disabilities, new conceptual tools are needed. Cloning and sequence analysis of the gene encoding L-lactate dehydrogenase from Lactococcus lactis: evolutionary relationships between 21 different LDH enzymes.

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Based on a self-designed questionnaire to evaluate the quality of life on 582 subjects. To determine the effect of instillation of normal saline before suctioning on oxygen saturation, heart rate, and blood pressure in patients with pulmonary infections. Antioxidant defence mechanism of the skin against UV irradiation: study of the role of catalase using acatalasaemia fibroblasts. The objective of this study is to determine if the plant sterol esters (PSE) in capsule form (1.3 grams of PSE/day) lowered plasma cholesterol levels and lipid ratios in free-living hypercholesterolemic subjects during a 4-week intervention period. Here we present a systematic comparison of our results with those obtained with use of other physics-based potentials by previous authors.

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Selective regression of cells expressing mouse cytoskeleton-associated protein 2 transcript by trans-splicing ribozyme. Infection of chickens (trial 1) and turkeys (trial 2) with K5054 resulted in little evidence of MG lesions.

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Plasma alpha-galactosidase A:properties and comparisons with tissue alpha-galactosidases. Theories of pathogenesis of external endometriosis are briefly reviewed. Stimulated and unstimulated saliva were compared as between individuals with selective immunoglobulin A deficiency (IgAd), common variable immunodeficiency (CVI) and immunocompetent individuals. Localization of parathyroid hormone-related protein mRNA expression in breast cancer and metastatic lesions by in situ hybridization. Thirty-two patients were followed prospectively with neuropsychological examinations at 3, 6, and 12 months after SAH.

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For heavy-charged particles, both most promising techniques, the distal edge tracking (DET) and the 3-dimensional scanning (3D) technique can be optimized. To examine the occurrence of polycystic ovaries (PCO) in women with gestational diabetes mellitus (GDM). Mosaic trisomy 16 ascertained through amniocentesis: evaluation of 11 new cases. Remission and relapse in schizophrenia: the Madras Longitudinal Study.

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The data suggest that the MetJ binding site on the aptamer is distinct from that of the natural DNA target, the 8-base pair Met box. Both peptides are processed from the recently identified Ala-Pro-Gly-Trp-amide prohormone, which is expressed in the neurons of the anterior lobe of the right cerebral ganglion.

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Within the therapeutic range (0.3-1.0 mmole/l Li), agreement was sufficient for venous and less satisfactory for capillary blood (mean differences, FES minus ISE: -0.03 and -0.11 mmole/l Li). It was found that, for most subjects in the group, astigmatism changed in the with-the-rule direction, the mean change being -0.036 DC at axis 176 deg for each dioptre of accommodation response. The specific changes that occur in the mesophyll could be diagnosed as inactivation of a carbon fixing enzyme as well as damage of the electron transport system.

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There is no evidence about whether penicillin prophylaxis is effective or ineffective against bacterial endocarditis in people at risk who are about to undergo an invasive dental procedure. The information gleaned permitted subsequent volunteer patients to be treated by a minimally invasive route. Both forms of dietary cyanides, however, had no adverse effect on bone development. Finally, we have found that the down-regulation of HAS isozyme expression (by transfecting cells with HAS1/HAS2/HAS3-specific small interfering RNAs) not only inhibits HRG-mediated HAS phosphorylation/activation and HA production but also impairs CD44-specific Cdc42-PAK1/filamin signaling, cytoskeleton activation and tumor cell behaviors. The purpose of the current study was to investigate the roles of combined selenium and iodine deficiency in bone development as a possible experimental model of Kashin-Beck osteoarthropathy.

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More than 12000 persons responded in 1987/88 and more than 7000 people in 1996/97. All these tumors have been previously screened for p53 mutations. Antitenascin-C monoclonal antibody radioimmunotherapy for malignant glioma patients.

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There were no recurrence after arthroplastic treatment and in localized lesions. Increasingly, blood centers worldwide are turning toward the ISO (International Organization for Standardization) 9000 Quality System Standards to meet regulatory demands of public authorities, competitive demands within their industry, and cost requirements from their customers. These data indicate that upregulated VEGF-A levels are most likely induced by enhanced HIF-1 binding to VEGF-A promoter, possibly contributing to elevated serum VEGF-A levels in CF.

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Univariate and multivariate analyses compared potential risk factors for injecting equipment sharing. The percent distribution of individual types of fibres was estimated as related to the calves age and diet.

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Contemporaneous chronic rejection of multiple allografts with principal pancreatic involvement in modified multivisceral transplantation. The only endogenous unconjugated steroids detected in the adjoining cortex were corticosterone and cortisol while in tumour tissue these were present in lesser amounts. Fifty-two patients were included in the study, and 44 completed the two 6-week periods of treatment. The central artery had a constant anastomosis with the opposite central artery in the inferior transverse third of the forehead. The systematic approach described categorizes health surveillance procedures into occupational or non-occupational, risk-based or unfocused, and as primary, secondary or tertiary preventive measures.

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Heparin coating of the cardiopulmonary bypass circuit reduces the activation of the terminal part of the complement cascade. Trichinelliasis in the wild and domestic animals of Kamchatka Province Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens. In the present work, we monitored the activity of the GAL10 gene promoter in different Ras-cAMP genetic backgrounds. After surgery, it was proven to be mycotic aneurysm related to Escherichia Coli sepsis.

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The majority of adolescents aged 12-17 years did not engage in multiple health-risk behaviors. Technical demands of the operation and two valves at risk have delayed acceptance. Short-chain fatty acids inhibit intestinal trefoil factor gene expression in colon cancer cells.

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The authors have shown that microvessel density and VEGF levels are independent prognostic markers of survival in fibrillary low-grade astrocytoma. Alternative access sites such as port insertion above the level of bar placement or left-sided and/or bilateral thoracoscopy may not be necessary. Superoxide anion as a mediator of drug-induced oxidative hemolysis. The C-terminal SH3 domain was used to affinity select peptides with the consensus, PXPPXRXSSL, from a library of X6PXXPX6 peptides. The program converged when the user ranked the same set of parameters as the best in three consecutive steps.

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Intracellular motility: myosin and tropomyosin in actin cable flow. The original study used a double-blind procedure to randomly assign 139 patients with histologically proven, unresectable pancreatic cancer to receive either an alcohol or a saline block. The absence of any changes in the succinic dehydrogenase and cytochromoxidase activity in the tissue of the skeletal muscles permitted to suppose that increase of the oxidative processes occurred primarily in the organs bearing a great functional load (the thyroid gland, liver, skeletal muscle, etc.). Substantial progress has been reported in the treatment of patients with alcoholism in the United States.