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Relaxation in the subcritical pitchfork bifurcation: From critical to Gaussian scaling. The practical aspects are delineated and a precise guide to postmenopausal oestrogen therapy presented. Cocaine increased DA and 5-HT to an equal extent in the PFC and PRC but induced a predominant 5-HT response in the EC. Similarly the addition of tetrodotoxin to the muscle bath had no effect on the ability of adenosine to produce its inhibitory response. cerevisiae npl3Delta strains, but its arginine-glycine-rich C terminus can fully substitute for that of ScNpl3 and also directs methylation-sensitive association with ScNpl3.

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Tumor-suppressive activities by chemokines introduced into OV-HM cells using fiber-mutant adenovirus vectors. Megakaryoblastic acute leukemia: identification by the ultrastructural demonstration of platelet peroxidase. In various countries all over the world, the congenital malformations are among the leading causes of infant mortality and children disability. We performed a literature search of the MedLINE and Cochrane databases since 1966 to 2006 using 8 keywords for articles of literature reviews or randomized controlled trials investigating physical training before and after hip and knee arthroplasty.

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In contrast, there were 6 femoral heads with osteonecrosis and 4 with ossification disturbance in Group C. How to evaluate intraexaminer reliability using an interexaminer reliability study design. Our results demonstrate that secreted FGFR mutants are uniquely effective as dominant-negative agents in vivo, and suggest that related soluble receptor isoforms expressed in wild-type mouse embryos may help regulate FGF activity during normal development. Transition from insulin U-40 to insulin U-100: the Belgian experience PHARMACOLOGICAL ACTIVITY OF 1-, 2-, AND 3-HYDROXYPROMAZINE AND 7-METHOXYCHLORPROMAZINE.

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Extracellular nucleotides regulate ion transport, mucociliary clearance as well as inflammatory properties of the airway epithelium by acting on P2 receptors. Most of the terminal stem-loop could be removed with little effect on the binding.

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Unlike other G protein-coupled receptors, the TSHR undergoes posttranslational cleavage of its ectodomain, leading to the existence of several forms of the receptor on the plasma membrane. Dimensional changes, gel layer evolution and drug release studies in hydrophilic matrices loaded with drugs of different solubility. The effect of fluoridation on the occurrence of hidden caries in clinically sound occlusal surfaces. We propose an automated approach that mathematically simulates the cell cycle process with the aim to describe the best estimation of the model. Postoperative complications occurred in 16 patients, and 10 of these complications were infectious.

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Intensive care unit of the Hamburg-Eppendorf University Medical Center, Hamburg, Germany. Intensive physical activity of high-class athletes leads to increase of blood coagulation expressed in shortening of the thromboelastogram r and K intervals and increased activity of the proth rombin complex according to Quick, and increased activity of factors II, VII, X, XIII, and fibrinolysis. Cases of traumatic ruptured globe after incisional corneal refractive surgery were collected from ophthalmologists and from peer-reviewed and other ophthalmic literature. Water quality assessment in the Aznalcollar area was attempted using multivariate methods based on heavy metal concentrations in red swamp crayfish (Procamburus clarkii).

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It should also receive almost antenatal care and care at delivery. Knee mechanics were assessed by measuring patellar tendon forces, gastrocnemius forces, knee flexor and extensor EMGs, and hindlimb kinematics before and 5, 7, and 9 days following ACL transection in six experimental and two sham-operated animals.

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Sporadic MERRF/MELAS overlap syndrome associated with the 3243 tRNA(Leu(UUR)) mutation of mitochondrial DNA. Structure prediction of cyclic peptides is important to evaluate possible conformations prior to synthesis. The functional significance of such a unique structure has not previously been established.

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During three months in 10-day courses they were given alternately 1 placebo tablet or 160 mg propranolol retard in one dose daily. This technique was successfully applied to the determination of inositol phosphatide turnover by AlF4-stimulation in a small amount (5.10(5)-1.10(6) cells) of cultured retinal capillary pericytes. In the current study, we investigated by atomic force microscopy and Kelvin-probe force microscopy how the increased level of cholesterol disrupts the assembly of an efficient film. Chemical aspects of derivatization and various alkylation (arylation) reagents and reaction procedures are described. The average number of codes logged before and after the start of the eighty-hour workweek were 407.3 and 455.3, respectively, for the junior residents compared with 501.2 and 480.6 for the senior residents.

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These disorders include hypertrophic cardiomyopathy, dilated cardiomyopathy and restrictive cardiomyopathy. Distribution of the pressure-regulated operons in deep-sea bacteria.

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This article reviews the factors associated with the prognosis of treatment with removable partial dentures. The effect of L-dopa and propranolol on human CSF cyclic nucleotides. Site-directed mutagenesis has shown that ligand recognition in the human P2Y(1)receptor involves individual residues of both the TMs (3, 5, 6, and 7), as well as EL 2 and 3.

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Among the fifteen cellular genes studied in cultured mouse C127 cells, vanadium (as 10 microM sodium vanadate) increased levels of mRNA of the actin and c-Ha-ras to four times control values. Longevity of spotted cucumber beetles was slightly shorter than longevity of banded cucumber beetles. Infectious diseases most often cited as causes of the plague include influenza, epidemic typhus, typhoid fever, bubonic plague, smallpox, and measles. Using the chaperonin 60 (Cpn60) gene identification method with reverse checkerboard hybridization and chemiluminescent detection, we identified correctly each of 12 S. The extent to which drugs exhibiting weakly acid or basic properties are ionized depends on their ionization potential (pKa) and the pH of their milieu.

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. Such a dichotomy has been criticized as being too reductionistic.

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Influence of weight and distribution of adipose tissue in functional hyperandrogenism Frequently bacterial pneumonias appear difficult to distinguish from Pneumocystis carinii pneumonia or other opportunistic lung infections, because of their atypical clinical and radiologic presentations. The scarcity of data on medical treatment with RU486, glucose 50 per cent, KCL, and actinomycin-D make proper evaluation impossible. In the human placenta, mononuclear cytotrophoblasts aggregate and fuse to form a multinucleated syncytiotrophoblast. Increased feeding efficiency in TLR4 mutant mice was associated with lower mass and lower expression of uncoupling protein 1 gene in brown adipose tissue.

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Taken together, these data show that LAG-3 has no transducing activity involved in NK cytotoxicity, ruling out the existence of a specific mode of natural killing defined by this molecule in humans. Thus, human, rat, and mouse 11beta-HSD1 have dual enzyme activities like the recently described 7alpha-hydroxysteroid dehydrogenase/11beta-hydroxysteroid dehydrogenase from hamster liver, but differ fundamentally from the latter in that 7beta-OH rather than 7alpha-OH dehydrogenase constitutes the second activity.

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Congenital hypodontia of maxillary lateral incisors in association with coloboma of the iris and hypomaturation type of amelogenesis imperfecta in a large kindred. The microalbumin urine test provides an early indication of the development of diabetic complications. Saturation labeling of cell surface antigens on HeLa cells on cover slips is obtained with the final sphere concentration of 10(14) DSS-marker/cm3 within 20 min. Androst-4-enedione (A), dihydrotestosterone (DHT) and 5alpha-androstanedione (5alpha-A) formation were measured by high-performance liquid chromatography coupled to a Flo-one HP radioactivity detector. The biological significance of a partial proteolysis of the plasma membrane proteins and the resulting soluble isoforms are discussed.

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Employing a mouse model of hyperoxic lung injury, a monoclonal anti-CD40 ligand (L) antibody (MR1), which disrupts CD40-CD40L interactions, was tested for the ability to reduce pulmonary injury. Multiphoton excitation and decay processes in xenon: Off-breakdown and breakdown emission at densities up to 1.4 x 10(2)1 atoms cm-3. The authors investigated knowledge, attitudes, and beliefs about mental illness and providers held by a group of deaf adults. The management of the chronically discharging ear requiring radical mastoidectomy.

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Adherence to published guidelines and improved education of surgeons are essential to the delivery of cost-effective medical practice. uPA levels in both stromal and epithelial cells were significantly correlated with those for uPAR. Differential display and cloning of messenger RNAs from human breast cancer versus mammary epithelial cells. She also has had lactose intolerance and a compression fracture without trauma.

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Limited information exists comparing the post-operative complication rate of laparoscopic or open abdominal surgeries in children with sickle cell disease (SCD). Potential benefits must be balanced against the risks of plasma pooling, while the increased costs will require comparison with other strategies such as quarantining of plasma. Despite these additional data on RER it is still uncertain whether its acceleration can prevent gastric ulceration or if its impairment leads to gastric ulceration.

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The systemic volume of distribution of the cationized 4D5 antibody was 11-fold greater than that of the native antibody. Nevertheless, close co-operation between oncological and oral health units is emphasised because many studies have shown that the oral cavity is indeed an important source of bacteraemia.

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To identify the characteristics of cytokine production from peripheral blood mononuclear cells (PBMCs) in response to lipopolysaccharide (LPS) in patients with subarachnoid hemorrhage (SAH). By contrast, neurons in the posterior horns did not show significant difference in their size. We report a case of aortoduodenal fistula 5 years after uncomplicated endovascular abdominal aortic aneurysm repair. We wanted to evaluate prospectively the feasibility of sonographic and Doppler assessment of the inferior mesenteric artery (IMA) and to provide data on its normal morphological and hemodynamic characteristics.

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These results show how a subtle chemical change of a peptide immunogen modifies the reactivity of the elicited antibodies in an unrelated manner from the peptide MHC II binding ability and T cell stimulating capacity. Preoperative diagnosis and surgical management of neuroendocrine gastroenteropancreatic tumors: general recommendations by a consensus workshop. After adjustment for disease severity, ICU and post-ICU mortality rates are higher in elderly patients than in younger populations. The percentage of the vertical division increased with progress in the stage of development, concurrently with the decrease of the population of horizontal divisions.

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mf should serve as an excellent source of material for genomic and proteomic studies designed to analyze the role of the parasite in influencing the immune response of the mosquito. The animals were evaluated at 6 and 12 weeks postureteroureterostomy with retrograde pyelography and differential creatinine clearances. Agitation scores in the postanaesthesia care unit were significantly higher in the ketorolac group, but this had no effect on the late variables of behaviour studied. Since the gastritis, gastric ulcers, atrophic gastritis, and intestinal metaplasia that developed in Mongolian gerbils were similar to those observed in humans, this model may be useful to study the therapy of gastric ulcer and, with a longer observation period, to confirm a possible relationship between H.

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Functional images were collected every 30 seconds by using a gradient echo pulse sequence. The results of this study in human coronary VSMCs indicate that angiotensin II and the AT1 receptor may be involved in the development of coronary artery disease in man. Signaling through a G Protein-coupled receptor and its corresponding G protein follows a stoichiometrically limited model.

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Complement activation in experimental and human temporal lobe epilepsy. Quantitative assessment of radiation-induced lung changes by computerized optical densitometry of routine chest x-rays. Use of the electrocorticogram (EcoG) in planning lesionectomies is a controversial subject at present. Nitric oxide synthase inhibitors modulate nerve growth factor-mediated regulation of amyloid precursor protein expression in PC12 cells.

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We found that preS/S proteins only become transactivationally active when truncated at the carboxy terminal end. To determine whether bone scan, magnetic resonance imaging (MRI), or somatostatin receptor scintigraphy (SRS) is best for identifying bone metastases in patients with gastrinomas, as well as their frequency and location, whether their detection affects management, and what patient subgroups should be examined. Physiologic function in the central nervous system can be measured using evoked potentials. Keratoacanthoma as a postoperative complication of skin cancer excision.

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Furthermore, a toluidine blue staining procedure is described for glycol methacrylate (GMA)-embedded material, which can be used if larger sections are needed. The changed epidemiology of hepatitis A infection in Scandinavia. Predictive values and ROC curves were used to assess the accuracy of FibroTest results. Sex refers to the anatomical or chromosomal categories of male and female.

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We have now used this system to explore the suggestion made by others that a negative feedback may exist between matrix mineralization on the one hand and the synthesis of alkaline phosphatase and bone matrix collagen on the other by analyzing the synthesis of these proteins and the levels of their mRNAs in mineralizing and nonmineralizing cultures. Insulin-like growth factors (IGF)-I and -II are present in milk of a number of mammalian species. Both enzymes proteolytically activated prothrombin to meizothrombin(desF1)-like molecules, while the activation cleavage seemed to occur at a site (Tyr(316)-Ile(317)) that is four residues proximal to the canonical Xa cleavage site (Arg(320)-Ile(321)). We have previously shown in the human cell line UAC that stomatin concentrates preferentially in plasma membrane folds and protrusions. The purpose of this study was to determine the site of MBP action on steroidogenesis in vitro using mouse Leydig tumor cells (MLTC-1).

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Adult-onset personality disorders, however, were also associated with significant impairment. The results demonstrate that adenosine A2a receptors increase, and adenosine A1 receptors decrease, the production of NO by human and porcine arterial endothelial cells. PYY and GLP-1 contribute to feedback inhibition from the canine ileum and colon. To date, however, the contribution of BCL-X(L) and STAT5 to the transforming phenotype in CML is still unclear. Change in the cleavage site of synthetic substrates of SsoII restriction endonucleases upon introduction of non-nucleotide inserts in the recognition segment

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Prevalence of markers for human immunodeficiency, hepatitis B and hepatitis C viruses in maxillofacial and oral surgery patients at Medunsa. Distinct mechanisms for trans-mediated mobilization of cellular RNAs by the LINE-1 reverse transcriptase. Each test improved diagnosis or timing of infection but no single test was ideal. Since the initial biochemical identification and description of the lipolysis stimulated receptor, several reports have been published by our group that provide circumstantial evidence for its role in vivo for the clearance of triglyceride-rich lipid particles. Increasing use of CT for evaluating neurologic disease may expose patients to considerable levels of ionizing radiation.

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Veterinary Management System (VMS): Innovative Veterinary Management Systems Ltd. Tax stimulated transcription through NF-kappaB and the cyclic AMP-responsive element-like sequence in the HTLV-1 promoter. Although N-nucleotide addition by TdT plays a critical role in the generation of a diverse repertoire of Ag receptor genes, the mechanism by which TdT acts remains unclear. Based on these results, the following hypothesis is formulated for the mechanism of intracellular ROS generation by treatment with 1: 1 taken into the target cells is reduced specifically by intracellular reductants such as NAD(P)H.

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How do mutated oncogenes and tumor suppressor genes cause cancer? Phacoemulsification surgery with polymethylmethacrylate IOL implantation with continuous curvilinear capsulorrhexis was performed. Restriction digests of YACs containing the CAG repeat sequence of the SCA1 gene were used as positive controls. Special notice was drawn in Polish studies on hemostasis disorders in acute experimental pancreatitis (AEP), and resulting clinical implications (possibility of thrombotic-embolic complications leading to hemorrhagic defects associated with coagulation factors consumption). Small intestinal transit and digestibility of lactitol in Wistar rats.

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The effect of sodium ion on antinociception and opiate binding in vivo. We show here that the serine/threonine kinase LKB1, previously implicated in the establishment of epithelial polarity and control of cell growth, is required for axon specification during neuronal polarization in the mammalian cerebral cortex. Patients underwent a routine ocular examination including slitlamp examination and a dilated fundus examination.

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The key secondary outcome was a verbal memory score, averaging performance on four measures of verbal memory. Sodium nitroprusside, a donor of nitric oxide, almost completely inhibits the generation of 1 alpha,25-(OH)2D3-induced osteoclast at high concentration (100 microM), but it significantly enhances the osteoclast generation at low concentrations (3 microM). The mucosal PGE2 content was decreased by SC-560 at 2 hr but recovered 8 hr later, and this recovery of PGE2 was attenuated by both atropine and rofecoxib but not omeprazole. EUS can best identify insulinoma, while for the differential diagnosis of cystic neoplastic lesions data provided by radial EUS are not sufficient.

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These results suggest that intranasal immunization with plasmid DNA-lipid complexes may represent a generic immunization strategy against pathogens transmitted across the genito-rectal and other mucosal surfaces. NSAIDs are used less by orthopedic surgeons than rheumatologists in our centre. Relatively fewer liver transplantations are performed both in the case of accepted indications such as primary biliary cirrhosis and acute liver failure, and for more arguable indications like post viral cirrhosis and alcoholic liver disease.

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Costimulatory signals are required for activation of immune cells, but it is not known whether they contribute to other biological systems. The remission rate after primary chemotherapy with anthracyclines (7 of 16) may be higher than in recurrent tumor (2 of 14).

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ON THE STANDARDIZATION OF HEMOGLOBINOMETRY IN POLAND FOLLOWING THE DIRECTIVES OF THE STANDARDIZATION COMMITTEE To search for correlations between intima-media thickness (IMT) and high titer of AECA in patients with systemic lupus erythematosus (SLE). A case of distal ectopic pregnancy involved the endocervical canal, and prompt diagnosis and treatment allowed the preservation of fertility.