Onapil is used alone or in combination with other medications to control certain types of seizures. It is also used to relieve panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Onapil is in a class of medications called benzodiazepines. It works by decreasing abnormal electrical activity in the brain.

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High signal intensity on T2WI around the tumor suggested that edema was greater and more extensive than in metastatic tumors and was seen even in the corpus callosum. The spatial transition from highly admixed to nearly pure native populations was abrupt, suggesting either cryptic barriers to dispersal or locally rapid displacement of natives by an advancing hybrid swarm.

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A single episode of neonatal seizures permanently alters glutamatergic synapses. As most of the studies on the regulation of renal 25-hydroxycholecalciferol-1-hydroxylase (25-HCC-1-hydroxylase) activity have been done in marginally-vitamin D-deficient animals and as it is known that vitamin D administration suppresses the specific activity of the 25-HCC-1-hydroxylase, it was decided to study the effect of dietary calcium on the activity of 25-HCC-1-hydroxylase and on Ca absorption in vitamin D-replete chicks.

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Similar to study I, nicotine replacement significantly suppressed number of cigarettes smoked, number of puffs, and carbon monoxide boost and increased latency to smoking, but there were almost no significant differences between the two nicotine doses. Tin-electroplating increased the bond strength of metal-ceramic gold alloy (Au,Pd,Pt) to a level comparable to the nickel-chromium alloy, but had a harmful effect on type IV gold alloy. Psychoanalytic conditions for realizing childhood daydreams exemplified by Heinrich Schliemann

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Character of changes of phospholipid bilayers microviscosity as affected by these compounds depends on their concentration in the solution. Doppler investigation of the fetal venous circulation may play an important role in monitoring the redistribution and may help to determine the optimal time for delivery.

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However, no direct evidence of the distinct roles of the TR isoforms has been shown. We have determined the primary structures of two human proteins with strong sequence similarity to the carboxyl-terminal domain of LBR and sterol reductases. Assuming sufficient gene transfer of CD in situ, CD/5-FC with TRAIL may be useful for the therapy of tumors resistant to TRAIL.

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A simple method for inference on an overall effect in meta-analysis. However, differences between the two types could be detected at an earlier stage of the infection.

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Recent technological innovations, specifically the introduction of a pooled internal standard, even further improve the quantification accuracy and statistical confidence of this method. These HRQoL measures can be used in future clinical trials to assess the effects of interventions postpartum.

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Role of cerebral phlebitis in acute encephalitis in children: anatomoclinical study Modeling of adsorption equilibrium for supercritical fluid mixtures, with as few parameters as possible, is important in applications of the technology of supercritical fluid adsorption. Mutating Ser-1034 to an unphosphorylatable Ala led to increased catalytic activity of ASK1 and enhanced proapoptotic function of ASK1. As bicarbonate is a buffer ion, the accurate measurement of intracellular pH (pHi) in duct cells is an important technique for studying the mechanisms of bicarbonate transport. Augmentation of the patellar ligament with a bone-patellar tendon-bone inlay allograft.

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Specific inhibition of human immunodeficiency virus type 1 replication by antisense oligonucleotides: an in vitro model for treatment. Exposure of human umbilical vein endothelial cells to Ang II elicited a rapid phosphorylation of Akt and FoxO1, a known target of Akt signaling. Age, gender, performance status, tumor stage, body mass index, serum creatinine levels, hemoglobin levels, white blood cell counts, and platelet counts were evaluated univariately and multivariately using logistic regression. However, these issues need not stand in the way of the development of innovative preventive approaches to the treatment of schizophrenia and other psychotic disorders. Our approach offers a novel methodology for determining the behavioral context of EEG in real time, and has potential application in automatic sleep-wake staging and in neural prosthetic applications for movement disorders and epileptic seizures.

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The repeated doses provided plasma concentrations above the minimal inhibitory concentration for Streptococcus zooepidemicus, S equi, Actinobacillus equuli and Rhodococcus equi isolated from the respiratory tract of horses. The plasmid is able to exist and to provide for exhibition of these properties both in autonomous and integrated state.

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Progressive neurological dysfunction was noted in those in whom the diagnosis was made late in the disease. A moderate decrease of triglyceride and total lipids develops in parallel with this, whereas free fatty acids considerably increase. The amount of hemoptysis was bleeding of 25-50 ml within 24 hr in 8 patients, recurrent blood-tinged sputum in 6, and bleeding of 100 ml or more per 24 hr in 5. Average International Prostate Symptom Score decreased from 19.2 to 3.7 at 6 weeks and it remained improved at 2 years (average 3.5).

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A conspicuous structural peculiarity was multiple fingerprint-like structures of the rough-surfaced endoplasmic reticulum (RER). This neurotoxin is stable in the medium at room temperature for several hours and withstands boiling. The in vivo performance of iv RF coils was demonstrated in a porcine animal model. Subcutaneous interstitial fluid pressure and arm volume in lymphoedema.

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Femoroacetabular impingement has been recently described as a common cause of hip pain and labral tears in young adults. Four related genes have been described in mammals (LYL-1, TAL-2, NSCL1, and NSCL2), all of which exhibit a high degree of sequence similarity to SCL/TAL-1 in the bHLH domain and two of which (LYL-1 and TAL-2) have also been implicated in the pathogenesis of T-cell acute lymphoblastic leukemia. Heparin is capable of solubilizing a subset of collagen-tailed (A12) acetylcholinesterase (AChE) molecules from skeletal basal lamina (Rossi, S. Recently, there has been a great deal of interest in the use of lentiviruses for gene transfer because they infect nondividing cells.

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Our findings also confirmed that the alkaline comet assay and nuclear deformations in addition to micronucleus test on fish erythrocytes in vivo are useful tools in determining the potential genotoxicity of commercial herbicides. Proportional hazards regression analyses that controlled for demographic and social characteristics, as well as reproductive attitudes, confirmed this cohort effect (hazard ratios, 1.5-2.6). The disorganization of scroll waves into chaotic behavior is thought to be the mechanism of ventricular fibrillation, which lethality is widely known. Does cyclic GMP mediate the slow excitatory synaptic potential in sympathetic ganglia? Cloning and sequencing of the Sphingomonas (Pseudomonas) paucimobilis gene essential for the O demethylation of vanillate and syringate.

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Hirudin possesses three disulfide bridges forming the structure of core cyclic peptides, which binds to the catalytic site of thrombin so as to inhibit the catalysis of thrombin. Structure-function relationships of peptide fragments of gastrin and cholecystokinin. Additionally, the upright posture of women presents these tissues with a greater mechanical challenge than in other species. A guanine nucleobase important for catalysis by the VS ribozyme. These data may lead to the use of these signaling molecules as targets to develop more effective chemopreventive agents with fewer side effects to control UV-induced skin cancer.

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Interscalene regional anesthesia in the prevention of autonomic hyperreflexia in a quadriplegic patient undergoing shoulder surgery. By IEM, employing specific antiserums for each virus, porcine rotavirus was found to be antigenically related to these 2 viruses, but not to the reovirus type 3. Treatment is aimed at reducing symptoms during relapse and prolonging the duration of remissions.

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Placental membranes were sent for bacteriological study after delivery in all patients. The duplications were completely linked and associated with the disease (lod score of 20.77 at zero recombination). Two of these genes, lydA and lydB of the dar operon, are 330 and 444 bp in length, respectively, with the stop codon of lydA overlapping the start codon of lydB. Cyclosporin A (CyA) has been used in steroid-dependent and steroid-resistant nephrotic syndrome (NS) with the aim to prolong or to induce remission, respectively. The maximum adhesive strength of the apatite layer to the specimen was significantly higher than that to the commercially available artificial bone, HAPEX.

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Combination chemotherapy with adriamycin and cyclophosphamide (with or without radiation therapy) for carcinoma of the lung. Due to the enormous number of these loci, we recommend careful analysis and cautious interpretation of studies of genetic markers, including microsatellites and single nucleotide polymorphisms (SNPs), as false positive and negative results are likely due to limited statistical power, multiple hypothesis testing, population stratification, or non-representative population sampling. Karyometric analysis was performed in a static cytometer using Feulgen-stained sections.

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We examined the effects of access modifications to home entrances of people with physical disabilities on their reported community outings. An enteroendocrine cell (EEC) line demonstrated a similar expression pattern of TLRs as primary cells.

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In some years, compounds of the silage caused strongly elevated plasma concentrations of acetoacetate after feeding. These results indicate that this mathematical model can be a valuable analytical tool to characterize, optimize, and further develop diagnostic measurement schemes that use venous occlusion approaches. Group differences in scalar and vector astigmatism were compared by using analysis of variance methods. Because several members of this pathway are conserved among eukaryotes, it is likely that a RAD53-related kinase will function downstream of the human ATM gene product and play an important role in the mammalian response to DNA damage.

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Age peculiarities of changes in the contractile function of isolated rat hearts during prolonged perfusion. magnesium sulfate reduces intra- and postoperative analgesic requirements in patients with almost identical levels of surgical stimulus. Further studies are needed to clarify if the administration of sevoflurane is safe in this population of patients.

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A retrospective review of a prospectively collected database was conducted of the records of all patients who underwent a pancreaticoduodenectomy for pancreatic adenocarcinoma between September 1991 and April 2005. Most reports on basilar artery (BA) occlusive disease have retrospectively described single cases or small patient series. This accumulation may be closely linked to radiation-induced lung injury. Some neurons in the cortex and ventral hypothalamus transiently expressed GABA-immunoreactivity on day E17. After successful hemostasis, the next goal is to prevent rebleeding.

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Evidence from our laboratory regarding the occurence of type C viruses in these patients is predominantly negative. Injections were also placed in two regions of the frontal lobe that were labeled by a parabelt injection in the same case. Among them, beta2 glycoprotein I (beta2GPI) is the most important. We found that HPK1 interacted with Crk and CrkL adaptor proteins in vitro and in vivo and that the proline-rich motifs within HPK1 were involved in the differential interaction of HPK1 with the Crk proteins and Grb2. We report the case of a young adult patient with a situs inversus and additional complex congenital malformations of the heart who underwent several prior palliative interventions, a biventricular repair being impossible.

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These data suggest that in the CNS the 2B10 antigen is expressed specifically on oligodendrocytes. Posttreatment of colchicine did not prevent the development of cerulein-induced pancreatitis. Neuropeptide Y antibody attenuates 2-deoxy-D-glucose induced feeding in rats.

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The effect of GH on bone was gender dependent, but not BMD dependent. This is an interim report of a personal evolution from staged correction of the bilateral cleft nasal deformity to synchronous repair of the nose and the lip and premaxillary-maxillary clefts. Rapid fabrication of microfluidic devices in poly(dimethylsiloxane) by photocopying. When a high salt concentration was used to decrease host cell protein synthesis in infected cells, polypeptides IV and (to a lesser extent) I were synthesized in relatively greater amounts than other cellular polypeptides, as were the viral polypeptides.

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Further study is indicated to determine the appropriate management and long term prognosis of patients with this lesion. Manipulation of the infectious bronchitis coronavirus genome for vaccine development and analysis of the accessory proteins. Bone mineral density in feline mucopolysaccharidosis VI measured using dual-energy X-ray absorptiometry. We also found that the difference in relapse risk between antidepressants and placebo was greater with the extension design.

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Trypsin treatment of the EBV-receptor colum abolished its ability to retain VCA-positive cells. Ophthalmic examinations including baseline and 6-month macular edema index values of patients by Heidelberg Retinal Tomography (HRT) macular module were done. Modelling of stomatal conductance and ozone flux of Norway spruce: comparison with field data.

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Low fat and complex carbohydrate diet along with regular aerobic exercise may help reduce abdominal obesity, improve insulin sensitivity and HDL cholesterol levels. If this system would be used worldwide, it would be a big leap in the management of GTN where results can be compared among different centers and large multicenter trials would be possible.

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It is well established that axons regulate Schwann cell phenotype. Fifty three patients, 18 of whom entered the study twice, were enrolled.

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In most of these cases either amphetamine or ecstasy had been used. Using TPN, gallbladder dimensions exceeded reference values without causing clinical complications. Especially with regard to withholding or withdrawing treatment from incompetent patients, more guidelines should be developed. Dexamethasone (Dex), cadmium (Cd), mercury (Hg), or zinc (Zn) increased (three- to fourfold) MT protein in the astrocytes, whereas methyl mercury, lead, and interleukin-1 and -6 were ineffective. Capacity of patients to mount recall immunological responses was measured by skin testing with two fungal antigens and three bacterial antigens.

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Expression of interferons-alpha and -gamma in testicular interstitial tissue and spermatogonia of the rat. An ultrastructural study of chronic cadmium chloride-induced neuropathy. Field trials of nivaquine, camoquin and resochin against human malaria. A structured questionnaire was designed to collect the reasons for affected births.

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The CT scans were reviewed for evidence of adrenal involvement by radiologists blinded to clinical findings. To review the results from the Veterans Affairs Cooperative Study on Glycemic Control and Complications in NIDDM (VACSDM) and to discuss the implications of the results from this feasibility trial. Those transfectants activated with IFN-gamma and LPS appeared highly resistant to NO-induced cell death detected within 24 h after stimulation, although their NO production was similar to those of parental RAW264 and neomycin control-transfected cells. Variance in the level of carer distress was accounted for by sleep disruptions, hallucinations and mood-related depressive features in patients and carer gender.

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Statistical analysis of 2 proportions with paired data: the McNemar test Physicians missed most cues and concerns and adopted behaviors that discouraged disclosure.

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The increase in reactivity of the tissue to enzyme hydrolysis paralleled the increase in dilution of formocresol. Rapid quantification of carotenoids and fat in Atlantic Salmon (Salmo salar L.) by Raman spectroscopy and chemometrics. The social security crisis: a European phenomenon, from the Atlantic to the Ural To counteract the detrimental effects of enhanced sympathetic activation on the heart, beta-blockade appears to be the proper choice.

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Estimated skin exposure as an indicator for comparing radiovisiography (RVG) versus conventional Ektaspeed Plus dental radiography. Vital pulpotomy in the primary dentition: attitudes and practices of community dental staff in Wales. We offer proposals that are based on the limited data available on the transmission and control of S.

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Intense study of the physical chemistry and cell biology of folding have greatly aided our understanding of the mechanisms normally employed. Our data show that, contrary to expectation and prior conclusions, the translocation of substrate-receptor complexes across the NPC in either direction occurs in the absence of NTP hydrolysis and is thus energy independent. Liquid chromatography/electrospray mass spectrometry is one of the rapidly developing techniques with which mass of large hydrophilic polymers such as proteins and nucleic acids can be determined precisely. The purpose of this study was to analyze management and clinical outcomes from a cohort of patients suffering colorectal injuries.

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For gamma-CD, the 1:2 species dominates, the other two being also present. Recently, HHV-8 was reported to be a possible etiologic agent of Kikuchi disease. Messenger RNA levels for the angiotensinogen and renin genes were quantified by RNAase protection assay in several tissues. MR imaging and pathologic findings correlated well in the chronic model. In the other patients the laboratory data were uncharacteristic.

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Reasons for not reporting victimizations to the police: do they vary for physical and sexual incidents? These findings suggest 99mTc-ECD and 99mTc-HMPAO have a different mechanisms of accumulation in the meningioma. Twenty-two newly diagnosed cases with hyperthyroidism were included in the study.

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Low and medium maternal mortality rate regions were found in northern and northwestern Mexico. Association between HIV-1 infection and miscarriage: a retrospective study. It does not require installation and can be directly Java-webstarted from http://3d-alignment.eu/metannogen/. We report three cases of Russell-Silver syndrome, all of which had dental anomalies.

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Sequence of b cytochromes relative to ubiquinone in the electron transport chain of Escherichia coli. The various biochemical processes which may contribute to cause these vascular lesions in obesity are discussed by the author and the various resulting clinical findings are described.