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Wistar rats subjected to chronic L-NAME treatment (40 mg/kg per day for 4 weeks) were used. And it was revealed that the active components were not only high moleculer substances but low molecular ones. Serum lipids in experimental atherosclerosis in guinea pigs treated with protein hydrolysate The best-fitting genetic model was the mixed codominant model, with a heritability of 0.32 and an allele frequency of 0.18 for high SBP level.

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Shedding of CD44 from MCT cells could be induced with crosslinking of anti-CD44 mAbs or with PMA stimulation. typhi DeltaompB strain carrying the ompC-lacZ fusions showed that both S. Since January 1988 until February 2002, 44 partial nephrectomies have been carried out in our unit because of renal tumors in 43 patients. In the primary OB cells, both ERalpha and beta mRNA were transcribed during the 25-day culture, but expression of ERalpha mRNA was much stronger than that of ERbeta mRNA. Introducing common European list will enable to collect reliable epidemiological data concerning occupational diseases (what can be useful in designing prophylaxis programmes) and will allow avoiding insurance problems arising from work-connected migration (according to the principle of free movement of workers).

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This defect was further pronounced when the cleavage site mutation between protease and RT was overexpressed as a consequence of an additional mutation that interfered with frameshifting. The effect on hearing conservation was evaluated according to ABR threshold. The picture that is emerging is that the programming of plant development may involve this supracellular network for the effective delivery of one form of information molecule. Transcriptome analysis of wound-specific early inducible genes showed that AtHEMA2 and AtFC1 were coinduced with hemoproteins outside plastids, which are related to defense responses. Incubation of slices with either light-inactivated MnTBAP or light-inactivated MnTMPyP had no effect on induction of LTP.

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At higher compression forces the crushing strength reached a constant level. Airborne fungal colony-forming units in outdoor and indoor environments in Yokohama, Japan. We investigated its possible involvement in the multidrug resistance phenotype (MDR) by analysing its level in two variants of CEM cells, namely S-CEM and R-CEM, normally sensitive or resistant to chemical apoptosis, respectively. It is thus appropriate to review the most important of these studies in light of the major issues that still impede widespread clinical use of cell therapy.

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Many products claimed to relieve respiratory symptoms and reduce toxins, with four herb-only products advertised for smoking cessation. For cells expressing activated RhoB, CXCR2 colocalized with Rab4, a marker for the rapid recycling pathway, and with the mannose-6-phosphate receptor, which traffics between the trans-Golgi network and endosomes. Endothelial-dependent dilator function was determined by the topical application of acetylcholine (ACh). The prevalence of abnormal aortic stiffness increases steeply with advancing age in the community, especially in the presence of obesity or diabetes. 19-channel eyes-closed EEG from 20 healthy males before and after 5 minutes of chewing the two gum types in random sequence was source modeled in the frequency domain using the FFT-Dipole-Approximation.

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Varicella recurrence complicated by pneumonia after liver transplantation for APECED. This study demonstrates that during hypothermic cardiopulmonary bypass, systemic vascular resistance under alpha-stat acid-base management is higher than under pH-stat management. Functional expression of human golgi CMP-sialic acid transporter in the Golgi complex of a transporter-deficient Chinese hamster ovary cell mutant.

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Difficulties of correlating acute symptoms and the effectiveness of mask use with serum thiocyanate are discussed. Diffuse Malign Mesotheliomas (DMM) has a low background prevalence. Different digital medical images have been printed on paper with a continuous ink jet printer, and the quality has been evaluated.

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Digital subtraction ventriculography in imaging the interventricular septum of the heart The method shows separation of neomycin B from seven potential related substances reported in the European Pharmacopoeia and several other unknown impurities. We have previously identified TGSGP as a gene specific to the Trypanosoma brucei gambiense subspecies. Tamoxifen is metabolized to reactive intermediates by endometrial tissue, and tamoxifen therapy-induced DNA adducts have been found in human endometrium. This indicates that the f2-sweep DPOAE phase delay is composed of a greater proportion of the filter response time at the site of DPOAE generation than the f1-sweep delay.

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The effect of IGF-I on phosphorylation of PI, a substrate of phosphatidylinositol 3-kinase (PI 3-kinase) or protein kinase B (AKT), was also examined in H9C2 cardiac muscle cells. Ectopic expression of both pMADS3 and FBP6, as occurrs in the petunia homeotic mutant blind, phenocopies the pMADS3 single overexpresser plants, indicating that there is no additive effect of concerted expression. The model was defined by recordings of cortical EEGs, maze performance, and behavioral observations. SOME OBSERVATIONS ON THE USE OF BAYER 1420, A NEW INTRAVENOUS ANESTHETIC

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Whether changes in left ventricular mass (LVM) in clinical practice predict survival and cardiovascular events in these patients is still unknown. Oxidative stress affects numerous intracellular macromolecules, and may result in cell death unless precisely regulated. It has long been acknowledged that pain is a subjective, multifaceted phenomenon which is influenced by many factors such as past experience and culture. Here, we report that somites of Myf-5-deficient mice lack the expression of FGF-4 and FGF-6 while TGF beta-2 is expressed normally. A retrospective review of medical records of patients treated between 1974 and 2002 was undertaken to identify factors associated with patient outcomes.

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Principles of management of adolescents with spina bifida in the ambulatory setting. Breast cancer survivors experience many demands of illness across the physical, psychological, social, and spiritual domains.

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A 3-week-old boy presenting with a cutaneous hemangioma and gastrointestinal bleeding was found to have gastrointestinal hemangiomatosis involving the entire small bowel diagnosed by exploratory laparotomy. A retrospective analysis was performed in order to evaluate prognostic factors and treatment-related outcome in patients with uterine papillary serous carcinoma (UPSC). The present study determined if KA lesions alter the suppressive effects of the antipsychotic drugs, haloperidol and clozapine, on spontaneous and amphetamine-elicited locomotor behavior.

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Although large changes in coupling properties are easily detected, subtle changes are often overlooked. Because it has been postulated that the cAMP-mediated regulation of energy balance in hepatocytes and adipocytes is channeled at least in part through the CCAAT/enhancer binding protein (C/EBP) family of transcription factors, we tested the hypothesis that C/EBP isoforms could be expressed in mouse cortical astrocytes and that their level of expression could be regulated by VIP, by the VIP-related neuropeptide pituitary adenylate cyclase-activating peptide (PACAP), or by NA. Brain CT showed brain swelling, predominantly in the posterior fossa, and bilateral subdural effusion. All H5N1 viruses, including the human isolate bound to Sia2-3Gal-containing receptors but not to Sia2-6Gal-containing receptors.

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The child underwent heminephrectomy and is currently doing well. after baseline measurement (day 1), subjects were randomized to 1 of 4 groups. Both proteins were found to be mitochondrial in human and rat islet cells and in many rat organs.

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In 4 cases of bone tumor in which extensive bone defects resulted from removal of the tumorous focus, vascular pedicle free fibular transplantation was performed using microsurgical techniques together with filling the defects with iliac bone. Implant-retained prosthetics represent a safe and effective treatment option. Specific features in the architectonics and structure of the mesodermal large vessels and their connection to the suprachoroidal capillaries for provision of adequate gas exchange are shown.

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Persistence of three-frequency quasiperiodicity under large perturbations. Second, bivariate latent growth models indicated that individual differences in personality change were substantially associated with change in peer and family relationships. In many katydids, the male feeds his mate with a large gelatinous spermatophore. Many-year experience gained by the authors permitted them formulate two causes of this rather poor state of the art: 1) no screening programs for the early detection of gastric cancer and 2) under-valuation of the frequency of endophytic (infiltrative) forms of gastric tumors and of potentialities of modern x-ray examination in the diagnosis thereof.

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Particularly productivity losses due to premature death represent a considerable burden to the Swiss society. The interaction between the high molecular weight NAD derivatives and enzymes are also discussed. Study of the effect of myxovirus and adenovirus infections on the level of serum immunoglobulins in infants aged 1-36 months

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No correlation was found between the percentage cells with FcR and CR and phagocytosis and clinical progression of neoplasma. This effect was attributed to an increase in free cytosolic calcium levels in pancreatic acinar cells.

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A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Previously, we established that alpha1(I)-CB7 (cyanogen bromide peptide 7), which lies within residues 552 to 822 of collagen, contains a major binding site for c-CAP(alpha1(I)-CB7 has been renumbered to account for an additional triplet recently identified at residue 613 (P.

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Injection of ANG I into the SFO also induced Fos-immunoreactivity (Fos-ir) in the AV3V region and in the vasopressin neurons of the supraoptic and paraventricular nuclei (SON and PVN). It was shown that absorption spectra of high spin cytochrome c and pK of transition from low to high spin form depend on the nature of adsorbent surface. A number of new initiatives and technologies now present the radiology community with the unique opportunity to fundamentally change the radiology report from free to structured text. The accumulation of apoptotic material is associated with a reduction in interleukin-10 in the spleen but an increase in interferon-gamma production in both the spleen and the atherosclerotic arteries. 125I-IGF-I cross linking indicated that IGFBP-4 overexpression reduced IGF access to the type-1 IGF receptor tenfold.

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This behavior provides a powerful tool for absolute-phase measurements. Sixteen clinical factors with a three-grade scale were used to evaluate complete denture prostheses in 320 patients.

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Rats were injected with bacterial lipopolysaccharide (LPS), and expression of the inducible isoform of NOS (iNOS), AS, and AL was analyzed. The expression of the CA1 and CA2 genes in the notochord in the tailed species, downregulation in the tailless species, upregulation in interspecific hybrids, and dependence on HNF-3beta activity is consistent with a role of these genes in development of the ascidian notochord. Quantitative sensory examination in human epidural anaesthesia and analgesia: effects of lidocaine. Clear phase differences were identified among the four cardiovascular variables studied. The structure of an unknown biomarker was shown to be different from the proposed 1a by gas chromatographic and mass spectrometric comparison.

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The data from this study demonstrate that anistreplase is a very valuable thrombolytic agent. Functional expression of human 5-HT1A receptors and differential coupling to second messengers in CHO cells.

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Extending acquired immunodeficiency syndrome (AIDS) case surveillance systems to include confidential (name-based) reporting of human immunodeficiency virus (HIV) infections provides data representing recent HIV transmission patterns. The balance of the bladder body was separated between muscle and mucosa and was analyzed for superoxide dismutase (SOD) and catalase (CAT) activities. Controlling for mental health in earnings equations: what do we gain and what do we lose? When known mutation carriers are removed from the group, no indication of further linkage to BRCA1 or BRCA2 is seen. The relationship of GTL to minimal change disease (MCD) and idiopathic focal segmental glomerulosclerosis (FSGS) has been disputed.

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Serum samples taken from patients at intervals during their stay in the hospital and at followup approximately four weeks later were tested by enzyme immunoassay for the presence of whole venom and therapeutic antivenom. These results suggest that our fluorescein operative microscope system is highly effective in surgery for malignant glioma.

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The results of our comparative analysis between the FSV and the FSC approaches indicate that the calibration patterns of VOC are highly sensitive to changes in injection volume or injection-related conditions. Proper repair of DNA damage is critical for protecting genomic stability, cellular viability and suppression of tumorigenesis.

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However, the laboratory finding of susceptibility to an antiviral material may not relate to its clinical effectiveness. It can be used to transform yeast cells from various stages of growth and storage. Furthermore we find that the crossover from antipersistent to persistent behavior is accompanied by a change in the type of volatility distribution. These results indicate that transgenic rice with significantly enhanced drought resistance and without yield penalty can be generated by over-expressing OsLEA3-1 gene with appropriate promoters and following a bipartite (stress and non-stress) in-field screening protocol.

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At 4W, the bony trabeculae were up to 3 times thicker than control trabeculae. Polychlorinated biphenyls, polycyclic aromatic hydrocarbons and molecular markers. The unfolding pathway for Apo Escherichia coli aspartate aminotransferase is dependent on the choice of denaturant. A similar amount of interferon-gamma and interleukin-10 induced by L.

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Therapeutic application of organ electrodermal diagnostics for pain. If the nerve growth factor (60 ng/ml) was added with the toxin to culture media, the effect of diphtheria toxin was seen to decrease and the neurite outgrowth was compared with control. In the follow-up the mediastinal image never appeared normal and the heart shadow was enlarged.

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In these experiments, the selectivity in the solubilization of individual PAHs parallels that of toluene extraction, although the yield is lower than the latter and varies with the soil sample. Fitness levels of American youth have shown a marked decline in the last decade, according to recent studies. The T-cell repertoire in PBMC was polyclonal and did not reflect the immune response in the graft. In all of our models, stable polymorphism of imprinting status is possible and mean fitness can decrease over time. A total of 367 primary-care practices (MediPlus, IMS Health) in Germany in the second year of the HealthCare Structural Reform Act were studied.

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A desensitization-type of neuromuscular block produced at pressure after neostigmine infusion could also be partially reversed by decompression. Each of the methods can be tailored to optimize resolution of a particular protein under a variety of conditions. A 24.7 kb segment of the cosmid clone pUKG047 containing a Sau3AI-partial fragment from the centromere region of Saccharomyces cerevisiae chromosome XI was sequenced and analysed. Aortic proinflammatory and profibrotic markers were determined by both quantitative reverse-transcription polymerase chain reaction analysis after 10 weeks of diabetes and immunohistochemical analysis after 10 and 20 weeks of diabetes. The PI-3 kinase inhibitor LY294002 had little effect alone but enhanced the response of most HDAC inhibitors as did the raf inhibitor GW5074.

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This is an effective, simple, comfortable, and inexpensive scalp dressing, which our patients have found to be very acceptable. The private practice radiology community relies on academic radiology departments to (1) do research and make advances in imaging science, (2) justify reimbursement for those advances, and (3) train new generations of radiologists. Fifteen out of 23 laboratories responded to the questionnaire and 12/23 completed the entire study. Detection of hepatitis B virus cccDNA in liver tissues of patients with hepatocellular carcinoma

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Endothelial cells and the axons of the neurohypophysis appeared weakly immunopositive or immunonegative depending on the fixative. Three successive surveys (January 1992, May 1994 and May 1996) about HIV screening policies among medical chiefs of all prenatal care and abortion departments of South Eastern France. To examine whether there are socioeconomic gradients in the incidence, prevalence, treatment, and follow up of patients with heart failure in primary care. To study this, we have made sequential deletions from the N termini of the gamma subunit isoforms and studied the interactions with alpha and beta subunits, both by two-hybrid analysis and by co-immunoprecipitation. SELEX provides high-affinity compounds for multiple targets in a mixture and might allow a means for dissecting complex biological systems.

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We conclude that the administration of UFT as an adjuvant therapy prolonged the overall survival and disease-free survival rates of patients after the resection of NSCLC in a small study performed at a single institution. Collisional-radiative and average-ion hybrid models for atomic processes in high-Z plasmas. Temperature variations altered active stress, but did not alter connective tissue properties or the Maxwell SEC stiffness. DBA/1 mice were pretreated with an immunodominant peptide, p245-270, from bovine type II collagen (bCII) and were subsequently immunized with whole bCII for the induction of arthritis.

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for variables which are commonly used as confounders or effect modifiers. This technique can be of value both in reoperating on an old saphenous vein graft implanted for infrainguinal limb revascularization and in harvesting fresh saphenous vein in which an unexpected short-segment stenosis has been encountered. Later, Cx43 expressing fibroblasts are observed, and the related Cx43 label increases over the 30 d observation period, even though fibroblast numbers decline after 12 d. Insulin receptor substrate-4 (IRS-4) is a scaffold protein that mediates the actions of insulin-like growth factor-I (IGF-I). Effect of test compounds on the aggregation and culmination of the slime mold Dictyostelium discoideum.

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The enzyme was strongly inhibited by monoiodoacetic acid, but not by diisopropylfluorophosphate, suggesting that it is a cysteine protease. The aim of this study was to determine the pharmacokinetic parameters of platinum after administration of oxaliplatin in cancer patients with severe hepatic impairment due to extended metastases into the liver.

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On the basis of these findings and recent crystallographic studies on cytochrome c oxidases, we discuss the possible roles of the conserved aromatic amino acid residues in subunit I of the heme-copper terminal oxidases. Strategies for the control of Cryptosporidium parvum infection in calves. Further examination of the relationship between anxiety sensitivity and depression: the mediating role of experiential avoidance and difficulties engaging in goal-directed behavior when distressed. Three K88ab binding proteins, of 67, 63 and 48 kDa, were identified on solubilized erythrocyte membranes and were recovered mainly in a detergent phase, suggesting a possible integral localization of the receptors.

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In order to elucidate the etiology of the loose shoulder, biochemical characteristics of deltoid and major pectoral muscles and skin collagen from patients with loose shoulder have been investigated. Intermediates in the conversion of procollagen to collagen were isolated from radioactively labeled chick cranial bones by ion-exchange chromatography.