Sitran nasal products are used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light). Sitran is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels around the brain, stopping pain signals from being sent to the brain, and blocking the release of natural substances that cause pain, nausea, and other symptoms of migraine. Sitran does not prevent migraine attacks or reduce the number of headaches you have.

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The results of this study showed that the majority of small valvular regurgitations disappear after light exercise. These findings suggest that MP was a teratogen when injected into the yolk sacs of developing embryos. Ninety-five patients were randomized in a 12-week, double-blind, placebo-controlled trial of sertraline, a serotonin-selective re-uptake inhibitor.

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Lower respiratory tract infections following cardiac arrest and cardiopulmonary resuscitation. We investigated the influence of timing of promethazine administration on postoperative pain outcomes.

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These different PBN locations receive inputs from the visceral and gustatory regions of the NST. There was no significant difference between the study and control eyes in the ERG amplitude or the implicit times of the a and b waves. This study was undertaken to determine the prevalence of visual hallucinations in patients with macular degeneration, describe such hallucinations phenomenologically, and possibly determine factors predisposing to their development. Do we have to use an inefficient method for the evaluation of our health care system? Relation of vitamin A and carotene contents in the organism to the presence of proteins in food

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The investigations focus on variables related to substance abuse such as self-image, social nexus, and perceptions of illicit substances. In line with this, CXCR3 is expressed preferentially in Th1 cells and in lymphoid organs of the IL-10(-/-) mouse that develops chronic colitis. Radiologic procedures are extremely valuable in the diagnostic work-up of many cancers but are limited for screening purposes to a few diseases.

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Cytochrome P450 4F12 (CYP4F12) was originally cloned from human liver and small intestine. Consequently, activation of the inhibiting GABA-ergic system should reduce anxiety and general motor activity and dim memory, whereas GABA-inhibitors should cause a contrary effect in relation to alarmed behavior. Long-term functional outcome and satisfaction after radial forearm free flap reconstructions of intraoral malignancy resections. Next we studied the effect of a reduction in site 1 affinity on cell proliferation. Intraparenchymal anesthesia infiltration during transjugular intrahepatic portosystemic shunting.

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Approaches for an explanation of the differentiating effect of all trans retinoic acid in acute promyelocytic leukemia. In contrast to fraction SX and fraction D, developed primarily to enhance immunity and suppress tumor development and growth, has essentially no effect on SBP under the conditions examined. The N3 potentials were noted at intensities of 80 dB nHL or greater. Effects of controlled mutations on the N- and C-terminal extensions of chick lens beta B1 crystallin. Laparoscopic management of small bowel incarceration caused by a broad ligament defect: report of a case.

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Helicobacter pylori in cirrhotic patients with peptic ulcer disease: a prospective, case controlled study. Neuronal expression of Fas-associated death domain protein and caspase-8 in the perinidal parenchyma of cerebral arteriovenous malformations. The third complementarity determining regions of heavy chain variable regions (CDRH3) confer the fine specificities of antibodies.

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The free energy, enthalpy and entropy changes for the closing reaction are 0 kcal x mol(-1), -11 kcal x mol(-1) and -0.037 kcal x mol(-1) x K(-1) at 300 degrees K respectively. Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages.

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Gastric residual volumes (GRVs), obtained by aspiration from a nasogastric tube, are widely used to evaluate feeding tolerance and gastric emptying, but controversy exists about what constitutes the true GRV (diet formula or digestive juice) and how it should affect management. Improved adiabatic calculation of muonic-hydrogen-atom cross sections. During the development of a solid phase extraction procedure for the chromatographic determination of eight antihypertensive compounds, lack of linearity and reproducibility was observed only for candesartan cilexetil. Humans are continuously exposed to a wide variety of xenobiotics either voluntarily or from environmental exposure. Chordae tendineae rupture in dogs with degenerative mitral valve disease: prevalence, survival, and prognostic factors (114 cases, 2001-2006).

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The polymerase chain reaction method (PCR) appears to be more sensitive and can be easily applicable to epidemiologic studies. We found that changes in clinical outcomes were predominantly dependent on comparative turn around time or CABG patient volume.

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We observe a similar relationship between structural complexity and activity in a comparison of two catalytic RNAs (ribozyme ligases), raising the possibility of a general relationship between the complexity of RNA structures and their functional activity. Investigation of causative agents of bovine respiratory tract disease in a beef cow-calf herd with an early weaning program. Surgical outcomes of cataract extractions performed by residents using phacoemulsification. Using an outcomes-based approach to identify candidates for risk stratification after exercise treadmill testing. Currently used antiplatelet drugs, including aspirin and ticlopidine, are effective against certain but not all of the many endogenous platelet activators.

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Effect of exercise on blood oxidant/antioxidant markers in standardbred horses: comparison between treadmill and race track tests. There were two missense mutations that altered the cleavage region of the signal peptide, seven missense mutations in exon 2, which codes for the conserved portion of the protein, one nonsense mutation in exon 2, and three nonsense mutations in exon 3.

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Undereating and undernutrition in old age: integrating bio-psychosocial aspects. Superficial femoral vein as vascular graft in surgical therapy of mycotic aneurysm of the common iliac artery Genotypic correlation between six common beta-thalassemia mutations and the XmnI polymorphism in the Moroccan population. Three viewing orientations (15, 45, or 90 deg elevation angle) were implemented in the perspective projection.

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The de-endothelialized rat carotid arterial graft: a versatile experimental model for the investigation of arterial thrombosis. Inhibition of deoxyribonucleic acid synthesis and replicon elongation in mammalian cells-exposed to methyl methanesulfonate. The author describes the principles of diagnosis, prophylaxis and correction of the disorders in blood coagulation, fibrinolysis and kinogenesis in this pathology. Preclinical pharmacokinetics and interspecies scaling of ragaglitazar, a novel biliary excreted PPAR dual activator.

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Docking of ATP to Ca-ATPase: considering protein domain motions. To discover whether the absence of this protein alters bone development, we monitored this event in the annexin-A1 null mice in comparison with littermate wild-type controls.

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Several platelet agonists have well-defined receptors at the platelet membrane of which a number are single polypeptides with 7 hydrophobic transmembrane domains. Thrombogenicity and procoagulant activity of human mesothelial cells. The results also indicate that apoptosis was altered by the expression of p53, bcl-2, ER, and PR.

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An unusual case of deafness with speech impairment: lesson in diagnosis and management. Vascular endothelial growth factor: molecular and biological aspects.

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The power patterns of the spine and hips were also significantly altered, particularly in subjects with a positive straight leg raise sign. Efficient integration of a realistic two-dimensional cardiac tissue model by domain decomposition. Initial investigations reveal that alpha-thrombin is a more potent inhibitor of 125I-PPACK-thrombin binding than PPACK-thrombin.

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The changes found were compared with the levels measured in a group of 10 healthy calves. Converging evidence that self-esteem serves an anxiety-buffering function. Our results emphasize the need for valve design changes, preoperative education about the sound, and inclusion of routine hearing tests into the preoperative workup. The whole colon was mobilized, a Foley-catheter introduced into coecum preferably through the appendicular stump or alternatively a terminal ileotomy and a scavenger tube was introduced into the left colon proximal to the obstruction. An international study is currently in progress to formally study the incidence, risk factors, treatment strategies and outcomes of stroke in children.

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RORA results are compared and contrasted with results from other base flow separation techniques. The results showed that birth interval was negatively correlated with sibship size, positively correlated with maternal age, and uncorrelated with paternal age.

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In contrast, all pigs inoculated with the virulent strain became progressively depressed and incoordinated, and were killed between days 6 and 9. The presenting signs were a tender, enlarged abdomen, depression and weakness. 2-Ethoxyethanol and 2-butoxyethanol were selected because they are among the most commonly used ethelyne glycol ethers, but little is known about their individual toxicity. Electron correlations in the double-excited helium isoelectronic sequence. The observation that the PA 382-384 mutant exhibits an increased thermal and proteolytic stability suggests that this mutant could be employed to solve the three-dimensional (3D) structure of human CK2 alpha and to overcome difficulties in crystallizing the native form.

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Overlapping EGFR antibody epitopes were determined based on a fluorescent competitive binding assay. A man (46 years-old) was admitted to the intensive care unit (ICU) with a history that eight hours before he had voluntarily drank 100 ml of malathion. To investigate how many people with schizophrenia are being treated by general practitioners (GPs) and what the associations are between GP characteristics and the number of patients with schizophrenia in their practice.

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Hence, examination of the long-term adaptation of HA to the four antibodies could reveal the strategy of the molecular evolution of HA. We report a patient with dilatation of the ascending aorta diagnosed at the age of 10 who presented acute aortic dissection and rupture after a 13-year period of follow-up. Confirmation of diagnosis ought to be the important information concerning future life style, work etc. By Western blot, the 6-His-tagged protein had a molecular weight slightly larger than native apoF. In this paper, I propose a method to estimate exposure prevalence when data are available only from a series of cases and an estimate of the relative risk for the exposure is available from published studies.

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Myelin was removed by phagocytosing cells at 8-14 d after the lesion, as demonstrated by electron microscopy. The prevalence for current smoking in the NA-AION patients was compared to the corresponding race-, gender-, age-, and period-matched subgroup of the U.S. Dendritic cell maturation and TCR affinity-based selection mechanisms control the recruitment and effective propagation of preferred antigen-specific Th cell cohorts in local lymphoid tissue. Expression of matrix metalloproteinases by human plasma cells and B lymphocytes. No maternal or developmental effects were observed in rats given 10 or 30 mg/kg/day or in rabbits given 15 or 50 mg/kg/day of PDC.

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The presence of osteopontin (OPN), which is one of the abundant proteins in bone matrix, is required for the effects of mechanical stress on bone, as we have reported that OPN-null (OPN-/-) mice showed resistance to unloading-induced bone loss. Early surgery brings longer remissions than in other types of bronchopulmonary cancer. Schizophrenic subjects demonstrated significantly less left frontal activation and greater left temporal activation than comparison subjects during a word fluency task. Transplantation of bone marrow-derived stem cells: a promising therapy for stroke. Gender differences in health care-seeking behavior for sexually transmitted diseases: a population-based study in Nairobi, Kenya.

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Site-directed random mutagenesis of the Ser130 codon yielded no other mutant with replacement of Ser130 besides Ser130Gly that produced ampicillin-clavulanate resistance. 12 schizophrenics each received 25 mg of ACTH for three days puring the maximum chlorpromazine dosage. Also in view of the possible side effects of muscle paralysis, our results question the usefulness of generalized administration of neuromuscular blocking drugs in mechanically ventilated patients. During the 7-8 year period, 17 children had died and 12 had migrated. We report a unique case of a squamous cell carcinoma of the larynx presenting as a large pseudolaryngocoele, arising through a thyroid cartilage defect.

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All the non-functional mutants, except two for which the mutant proteins were undetectable on immunoblots, showed interference of normal secretion. Since atrial flutter frequently occurs after Mustard and Senning operations in which suture lines are similar as for creating the lateral tunnel in TCPC we postulated that our technique for creating the intercaval tunnel without prosthetic material might prevent atrial flutter.

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Gravel, mascara, high explosives, and older tattoos responded best with total clearance after 2-5 treatments. In summary, it is concluded from the immunocytochemical data presented here that the association of OPN and OC with mineralized regions of the extracellular matrices of bone and cartilage and the accumulation of these proteins at tissue surfaces and interfaces are consistent with the hypotheses that they play a role in the extracellular mineralization process per se and/or that they may mediate cell adhesion and dynamics. Among female patients, a significant decrease in estradiol, total and free testosterone and an increase in FSH and SHBG was found. PCP was analysed in post-shift urine samples of 189 painters and 148 bricklayers by gas chromatography and electron capture detection (GC-ECD).

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Furthermore, results provided the first evidence that there is an endothelium-dependent cross talk between alpha1-adrenergic and angiotensin II receptors in smooth muscle of rabbit aorta. An audit of gunshot injuries was conducted at the University College Hospital to determine the pattern of injuries. Lysis of feline lymphoma cells by complement-dependent antibodies in feline leukemia virus contact cats.

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Males of a substrain of Munich-Wistar rats (MWF/Ztm), selected for their large number of superficial glomeruli, develop spontaneous proteinuria with age, whereas females of this strain have a normal urinary protein excretion rate. This study evaluated the effectiveness of a technology-based psychoeducational intervention for family caregivers of dementia patients. A Technique for Freezing Goat Semen and Results of a Small Breeding Trial. Molecular methods recently have shown that anamorphic species such as members of Malassezia or Tilletiopsis should be included in this group.

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Taken together these results suggest that the PDZ domain, particularly the B region, of LIMK1 has a specific function to localize the protein in the cytoplasm. Low dietary intakes and tissue levels of long-chain (LC) n-3 PUFA in South Asian populations have been linked to high-risk abnormalities in the MetS.

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Anchoring of nematic liquid crystals on terraced silicon surfaces. Low concentration antibiotics sterilise venous-tissue without affecting smooth muscle cell viability. Ten per cent of all new cases of AIDS in the United States are in persons older than 50 years.

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The rapid growth of the human fetal adrenal gland, which is primarily a reflection of the growth of the unique fetal zone, is regulated by ACTH acting indirectly to stimulate the expression of locally produced growth factors, of which IGF-II and bFGF appear to play key roles. An epidemiological and environmental approach is the appropriate starting point to understanding preterm labour. The RNA preparations from regenerating liver tissues collected at various intervals following partial hepatectomy, and from normal liver samples of BALB/c mice, were hybridized to 3H-DNA complementary to 60 to 70S RNA of an endogenous, N-tropic virus, released spontaneously from BALB/c mouse cells in culture. Corticosteroids reverse the inhibition of Na-glucose cotransport in the chronically inflamed rabbit ileum. In the remaining two cases, a normal visual outcome at 5 years was associated with visual abnormalities at 5 months but these had already normalised by the age of 1 year.

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The uterus and fallopian tubes represent a functionally united peristaltic pump under the endocrine control of ipsilateral ovary. Upon evaluation of six compounds (5-7, 9, 10, and 13) for inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation (1 microg/ear) in mice, four saccharide fatty acid esters, 5-7 and 9, exhibited potent anti-inflammatory activity, with ID50 values of 0.46-0.79 mg per ear. An r value of 0.7 or greater was considered evidence of colinearity. The recent data on the processes of aggregation, budding and maturation are summarized here. Unlike other RGS proteins such as RGS9, RGS-GAIP, and Sst2p, which have been reported to be largely membrane-associated, a majority of cellular RGS4 is found as a soluble protein in the cytoplasm.

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Hence, there is growing interest in how to best tailor and individualize the treatment of hypertension according to the circadian BP pattern of each patient. As to the animals models to study Parenteral Nutrition, we could make the next classifications and sum it up: (1) Animal models to study the parenteral via of administration. GC-MS of metal chelates has been shown to be useful in studies of Cr and Se metabolism and for the determination of a number of other metals.

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Initial therapy consisted of multiagent chemotherapy and vulvar, pelvis and groin irradiation. Emergence of bidirectional accessory pathway conduction in adulthood. Changes in polyamine levels and protein synthesis rate during rat liver carcinogenesis induced by 4-dimethylaminoazobenzene.