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Kivexa (Abacavir)
+ BONUS
 
Abacavir

Kivexa is a drug used as part of antiretroviral therapy (ART). It is manufactured by ViiV Healthcare. The FDA approved Kivexa late in 1998. Generic versions have been approved under PEPFAR. Kivexa is a type of drug called a nucleoside analog reverse transcriptase inhibitor, or nuke. These drugs block the reverse transcriptase enzyme. This enzyme changes HIV’s genetic material (RNA) into the form of DNA. This has to occur before HIV’s genetic code gets inserted into an infected cell’s own genetic codes.

Other names for this medication:
Abacavir, Abalam, Epzicom, Kivexa, Abamune, Virol, Ziagen,

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Kivexa is used along with other medications to treat human immunodeficiency virus (HIV) infection. Kivexa is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Although Kivexa does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer. Taking these medications along with practicing safer sex and making other lifestyle changes may decrease the risk of transmitting (spreading) the HIV virus to other people.

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The RNA of mouse hepatitis virus, a coronavirus, was isolated from the virus released early in the infection and analyzed by sucrose gradient sedimentation and electrophoresis. Replacement of endogenous phospholipids in rat plasma lipoproteins during intravenous infusion of an artificial lipid emulsion. Cultured blastocyst outgrowths are a model for implantation events of the trophoblast/placenta lineage and endoderm/yolk sac lineage.

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Bevacizumab, a humanized monoclonal antibody to vascular endothelial growth factor (VEGF), has been given via intravitreal injection as an off-label therapy for both neovascular age-related macular degeneration and for macular edema secondary to retinal vascular disease. Comparison of different nuclear DNA markers for estimating intraspecific genetic diversity in plants.

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Three other patients could not be treated with the stent because deployment was not possible after correct positioning of the delivery system. Although one of these agents, calcitriol, has repeatedly demonstrated antiproliferative properties against cancer of the prostate, breast, colon, and lung, the antineoplastic activity of calcitriol requires superphysiologic levels. Health benefits from reducing indoor air pollution from household solid fuel use in China--three abatement scenarios. FeLV epidemiology in Los Angeles cats: Appraisal of detection methods.

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Distribution of the alpha7 nicotinic acetylcholine receptor subunit in the developing chick cerebellum. This study examined the antiparkinsonian activity of the hydroalcohol extract of Ilex paraguariensis in models of protection against cerebral injury induced by MPTP and reversal of the catatonia induced by reserpine in mice.

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The purpose of this preliminary study was to evaluate the usefulness of power Doppler sonography in differentiating metastatic from nonmetastatic cervical lymph nodes in patients with cancer. Glycoprotein (Gp)IIb/IIIa molecules have been immunoprecipitated from platelets and leukocytes of cattle, goat, horse, human, sheep and swine using specific monoclonal antibodies.

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Deregulation of cyclin B1 was seen with a sublethal dose of cisplatin. Reverse transcriptase and real-time PCR were used to evaluate the KDR mRNA expression levels in 222 tissue samples (106 tumor tissues, 106 matched normal tissues obtained from the same patients with lung cancer, and 10 normal lung specimens from individuals without lung cancer). However, more aggressive treatment, including craniofacial resection, should be considered in IP with SD, which is associated with a high rate of recurrence and malignant transformation. The animals were euthanized at week 4 post-surgery and block biopsies of the defect sites were collected for histologic and histometric analysis. CHO1-depleted cells reached a late stage of cytokinesis but fused back to form binucleate cells because of the absence of the midbody matrix in the middle of the intercellular bridge.

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Increased vascular O-.2 is likely secondary to a PKC-mediated activation of a membrane-associated NAD(P)H-dependent oxidase. Outside a clinical trial, postoperative radiotherapy (30 x 2 Gy) remains the standard adjuvant therapy for most patients. Chromosomally normal gametes can result in abnormal embryos manifested by arrested development and unexplained infertility. Hyperdiagnosis of myocardial infarctions as shown by analysis of hospital mortality

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Human adiaspiromycosis: cicatricial lesions in mediastinal lymph nodes Pretreatment with antibody to corticotropin-releasing factor via the intracerebroventricular route abolished the increases in corticosterone induced by intracerebroventricularly administered aFGF, but not those induced by intravenous injection of aFGF. Between January 1992 and December 1995, eight patients with cervical carcinoma IA2 or IB1 underwent laparoscopic radical hysterectomy at China Medical College Hospital, Taichung, Taiwan, R.O.C. We describe the radiological and laboratory work used to bioengineer a new laryngeal mask prototype, the intubating laryngeal mask airway (ILMA). We performed a MEDLINE search of studies published between 1966 and September 2005 and a retrospective cohort study in children aged 0 to 16 years.

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Our findings suggest that maternal leptin concentration during pregnancy is not an accurate indicator of fetal growth. The authors examined 66 patients with ischemic heart disease and concomitant cervico-thoracic osteochondrosis and 22 patients without osteochondrosis. In the given case, however, the unchanged FCECG in the above patients reflected the impairment of stimulation spreading in the left ventricular myocardium rather than the lack of its hypertrophy. Synthesis, isolation, and characterization of the adduct formed in the reaction of p-hydroxyphenylacetaldehyde with the amino headgroup of phosphatidylethanolamine and phosphatidylserine.

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Antisera to the 43-, 42-, and 22-kDa OMPs, but not the preimmune sera, significantly reduced V. Synapses of multiple sets of glutamatergic and GABAergic afferents subdivide the surface of cortical neurones and are often co-aligned on the dendritic domain. Free radical generation at the solid/liquid interface in iron containing minerals. Circulating levels of testosterone (T), estrone (E1) and 17-hydroxyprogesterone (17-OHP) were altered while serum concentrations of androstenedione (A), dehydroepiandrosterone (DHA), dehydroepiandrosterone sulfate (DS) and urinary 17-ketosteroids (17-KS) were not. Second, nuclear machineries for the synthesis and processing of RNA and DNA are associated with an insoluble nuclear structure, called nuclear matrix.

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Connective tissue bands and muscular slips draping or enclosing this neurovascular bundle have been reported, however, which may produce clinical symptoms of nerve compression and vascular changes. Fifteen mated bitches were used to study the effects of prostaglandin F(2alpha) on ovarian endocrine function during the early and midluteal phase. Nursing care across the service delivery continuum is essential for patients undergoing simultaneous kidney pancreas transplantation. The influence of candesartan and PD123319 on responses to angiotensin II in the hindquarters vascular bed of the rat. All four proteins have intra-chain thioesters located within their highest molecular mass polypeptides.

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Effect of various exposure scenarios on the biological monitoring of organic solvents in alveolar air. Two studies were conducted in western Canada to evaluate the impact of antiparasitic treatment on weight gain and reproductive performance in beef replacement heifers from weaning to first breeding.

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Surgical treatment of concomitant chronic ankle instability and longitudinal rupture of the peroneus brevis tendon. Physical mechanisms and biological significance of supramolecular protein self-assembly. On the other hand, the ambulation-increasing effect of ketamine (12.5 mg/kg, s.c.) was significantly suppressed by ceruletide (0.01 mg/kg, i.p.), alpha-methyl-p-tyrosine (100 and 300 mg/kg, i.p.

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Serum cholesterol and lipoprotein concentrations in mothers during and after prolonged exclusive lactation. The purpose of this report is to review the presumable pathophysiology and the clinical and radiographic features as well as the pitfalls in diagnosing postarthroscopic osteonecrosis of the knee.

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Mutation of Arg to Lys (alpha R209K) or His (alpha R209H) at position 209 shifted the EC50 for ACh slightly from 5 microM to 12 microM and increased the normalized maximal channel activity 8.5- and 3.2-fold, respectively. Occurrence of carcinogenic amino-alpha-carbolines in some environmental samples. Inhibition of TRAIL-induced activation of NFkappaB augments apoptosis induction by TRAIL and attenuates apoptosis resistance.

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The prognostic value of the inducibility of en-TNF by colorectal tumor cells from colorectal cancer patients who received curative operation at Dukes Stage C was confirmed. The distance between the caudal aspect of the lateral crus and alar skin margin was less than 6.7 mm on average for the anterior 15 mm of the lateral crus. Resistance of transmissible spongiform encephalopathy agents to decontamination.

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Interstitial laser coagulation in the management of lower urinary tract symptoms suggestive of bladder outlet obstruction from benign prostatic hyperplasia: long-term follow-up. Adsorbates were assayed after incubation periods of up to 26 hours using specific ELISAs. The dependence between the increase of cathepsin B activity and the FIGO stage of the disease was observed only for serous and endometrioid type of ovarian carcinomas. The retina of all 3 SARDS-affected eyes had numerous (34, 61, and 70) apoptotic nuclei per section that were overwhelmingly located in the outer nuclear layer.

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We report a case of a laparoscopically performed modified bilateral retroperitoneal lymph node dissection for clinical stage 1 testicular cancer. The numbers of labeling errors were again assessed in 2,421 consecutive plain radiographs over a 2-week period. Administration of estrogen, testosterone, and dexamethasone to immature female rats did not alter NTBP capacity of affinity. The etiology, and hence most effective treatment, of cerebral vasospasm remains unknown, thus this devastating sequela to subarachnoid hemorrhage continues to be responsible for significant morbidity and mortality.

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Veralipride is a substituted benzamide which is used for the treatment of menopausal hot flushes. Progressing reduction of graft density was found in relation to healthy bone density. Our results demonstrate the high sensitivity, specificity and reproducibility of this technique, and its usefulness for rapid laboratory diagnosis of invasive aspergillosis.

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