Larus is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (e.g., chest pain, heart attack, or stroke) that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel problems in patients with risk factors for heart problems.

Larus belongs to the group of medicines called HMG-CoA reductase inhibitors, or statins. It works by blocking an enzyme that is needed by the body to make cholesterol, and this reduces the amount of cholesterol in the blood.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet

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Natural genetic transformation of Pseudomonas stutzeri in a non-sterile soil. Intracoronary dipyridamole reduces the incidence of acute coronary vessel occlusion in percutaneous transluminal coronary angioplasty--a prospective randomized study The virus was regularly detected in the blood of the animals by the method of co-cultivation of leukocytes and human embryo fibroblasts for 70 days (the observation period).

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The primary outcome measure was retinal reattachment after primary vitrectomy without any reoperations at 6 months. Genetic structure and variability were investigated in several Hawaiian populations of D.

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In contrast to other samples, the UHMWPE evaluated did not show any kind of cavitation or cracks, and this might be an indicator for a positive development. When the dura mater was opened, the anterior view of the pons and medulla with corresponding cranial nerves and vasculature was encountered.

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Effectiveness of RF capacitive hyperthermia combined with radiotherapy for stages III and IV oro-hypopharyngeal cancers: a nonrandomized comparison between thermoradiotherapy and radiotherapy. Light adaptation after bleaching visual pigment produces a reduction in the deduced rise of phosphodiesterase activity for all flashes. Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.

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The quartz crystal microbalance (QCM) may give a direct response signal which characterizes the binding event between a sensitive layer, immobilized onto the surface transducer, and the analysis to be detected. Our studies suggest that upregulation of CRK13 leads to hypersensitive response-associated cell death, and induces defense against pathogens by causing increased accumulation of salicylic acid. Pretreatment with 0.5 mug/ml/day of BrdU inhibited the ACTH-induced differentiation of cortical cells as well as the secretion of corticosterone and 18-OH-deoxycorticosterone (18-OHDOC). If targeted screening were to be considered, the group most likely to benefit would be recently arrived migrants from Indochina.

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Severe cases seem to develop primarily among patients in regular haemodialysis therapy at exposure. Twenty-five patients undergoing PMBC were enrolled in this study. Moreover, the postsynaptic population responses increased in number and suggested strong repetitive firing. Two different murine sarcoma virus isolates have homologous genome sequences: implication for their origin. Our data suggest that high t-PA circulating levels in liver disease could be related not only to the reduced t-PA clearance as a consequence of liver injury but also to hemodynamic changes.

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Additionally alterations of synthesis of collagen fibers and ground substance by fibroblasts with histiocyte-like features contribute to a further gradual decrease of the growths. The associations of linear alkyl benzenes with the bulk properties of sediments from the River Mersey Estuary.

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It is possible that LHRBI induced enhanced synthesis and/or secretion of progesterone by the ovarian follicles thus suggesting a role for LHRBI in ovarian function. After resection of the brain metastases, with no evidence of additional metastases, the patient underwent left radical nephrectomy and tumor venous thrombectomy.

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Melanoma susceptibility and cell cycle genes in Xiphophorus hybrids. Similarly, the introduction of 3D mapping systems has enhanced our understanding of arrhythmia mechanisms and allowed for integration of electrophysiologic and anatomically guided ablation. The concept of blood flow directly from the left ventricular chamber into the myocardium is not a new one, and recent studies have found the potential for this application in human hearts.

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Furthermore, the serum lipid (triglycerides, total cholesterol and phospholipids) concentrations were also significantly decreased. Charting the progression in semantic dementia: implications for the organisation of semantic memory. In conclusion, specifically determined ASC concentration sensitively reflects oxidative stress in tissues.

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Delineation of the common critical region in Williams syndrome and clinical correlation of growth, heart defects, ethnicity, and parental origin. Although the pathological diagnosis of a pilocytic astrocytoma would not justify radiotherapy, local field radiotherapy was added mainly because of the unexpectedly rapid tumor progression during the interval between the two surgical procedures. Because these injuries are relatively uncommon, the amount of clinical data available to guide treatment decisions is limited.

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There is also a tight age-dependent and spatial regulation of the molecules in the various cerebellar neurons. The present study was designed to determine circulating ADMA levels and endothelium-dependent, NO mediated vasodilation in a rat model of congestive heart failure (CHF).

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Treatment of leucopenia with pure Astragalus preparation--an analysis of 115 leucopenic cases The DeltaNDeltaC156S mutant may provide a valuable tool for the analysis of VEGF-C effects mediated selectively via VEGFR-3. ICC improved to 0.90 for HVA and 0.91 for MHPG when the average of the first 2 days was examined against the average of the last 2 days.

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In the Stockholm area, co-circulation of genotypes A, C and D at different times was found. Comparison of solvation-effect methods for the simulation of peptide interactions with a hydrophobic surface. Using human 19 K cDNA microarrays, we show that 1757 genes are exclusively regulated by TGF-beta in A549 cells in contrast to 733 genes exclusively regulated in HPL1D cells.

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Furthermore, immunostaining studies indicate that, at least in clinically affected hamsters, astrocytes are the first site of this glycation process. This study examined the correlates of injection drug use (IDU) in a community sample of psychostimulant users. Under shear stress, neutrophils attached equivalently to wild-type and 6 CR P-selectin and nearly as well to 5 CR P-selectin.

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In clinical dentistry, the sounds (clicking) and noises (grating) produced by the temporomandibular joints (TMJ) usually signify dysfunction or disease of the mandibular locomotor system. The hydration forces that operate on the microscopic scale of individual amino acid side chains, implied by the small angle scattering data, could have significant effects on the early stages of protein folding, on ligand binding, and on other intermolecular interactions. Computed tomography features of cerebral spread of malignant melanoma. This study analyzes the cellular sites of altered IGF-I and IGFBP-expression in large bowel of rats with experimental colitis. Self-reported dental health and dental appearance were associated with satisfaction with pain management, quality of care, access to care, and overall satisfaction.

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From these three techniques the CIAP monitoring via the bladder has excellent agreement with the current standard of intermittent bladder pressure measurement. Psychophysical experiments were conducted on normally sighted human subjects, who were required to walk through a maze which included a series of obstacles, while their visual input was restricted to information from a pixelized vision simulator. A water-soluble polysaccharide extracted from leaves of the Meliaceae Cedrela tubiflora was separated into neutral and acidic polysaccharide fractions. To investigate the mechanism whereby Nrf2 contributes to the susceptibility to autoimmune diseases, we generated nrf2-/-lpr/lpr mice.

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Radiofrequency ablation of accessory pathways: a 14 year experience at the Tel Aviv Medical Center in 508 patients. By means of chemical methods and immunodiffusion technique it has been shown that low density lipoproteins incorporate into the structure of fibrin clot formed both in purified systems and in the blood plasma. During the mitochondrial biogenesis that accompanies phenotypic adaptation, the stoichiometric relationships between functional elements are preserved through shared sensitivities of respiratory genes to specific transcription factors. A plate-screening protocol was developed with improved thermostability as a selection criterion. Coronary heart disease risk factors in women: focus on gender differences.

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Distribution of amino derivatives of phenothiazine in the animal body. The role of bipolar prostheses and total hip replacement is uncertain. Functional versus standardized assessment procedures: implications for educational programming.

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Finally, all three smokeless tobacco extracts activated the alternative pathway since significantly elevated levels of the cleavage fragments iC3b and Bb were detected in extract-treated serum. We examined MRI abnormalities and language function in young patients with infarctions apparently confined to the basal ganglia to establish whether impaired performance was attributable to basal ganglia damage per se or to additional cerebral abnormalities. The purpose of this study was to report the varied radiological and dermatological manifestations of our patients affected with NBCCS and to present this rare syndrome as a differential diagnosis of skeletal anomalies. On each occasion, insulin dose, amount of food, and type of food were consistent for all 3 BGCs.

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Several studies concerning anemia prevalence were carried out in Brazil with pregnant women and children aged less than 5 years, restricted mainly to northeast and southeast regions of the country. Coral record of equatorial sea-surface temperatures during the penultimate deglaciation at huon peninsula In contrast, specialized progenitors do not contribute to adult beta cells, not even during acute beta cell regeneration. Its benefit was estimated as high as 8.71/10 in average by parents. In the final group, the infusion of urokinase was delayed for 3 h.

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Unlike analogs bearing hydrocarbon substituents at C-4, the resulting dihydropyridinium metabolite did not undergo further oxidation to the pyridinium compound but rather underwent hydrolytic cleavage. Is higher contrast-enhancement on post-contrast CT image enough to make the differential diagnosis between AML and RCC? Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Asthma is characterized by bronchial hyperresponsiveness (BHR), bronchial mucosa inflammation and airway epithelial damage.

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Reporting this case might encourage forensic practitioners having experience of a similar case to respond through this journal. Relationship between flushing pressure and nitric oxide production in preserved lungs. Prenatal DEX decreased the concentration of nonsedimentable proteins in ELF and decreased the inhibition of surface activity by these proteins.

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While the crystal orientation of matrix Nd2Fe14B grains was analyzed by nanobeam electron diffraction, precipitates of a few tens of nanometers at grain boundaries were identified to be alpha-Fe by energy-dispersive X-ray spectroscopy. One of these benzamides, CTPB (N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide), was discovered as a potent activator of the p300 HAT activity. Anticancer neuroimmunomodulation by pineal hormones other than melatonin: preliminary phase II study of the pineal indole 5-methoxytryptophol in association with low-dose IL-2 and melatonin.

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A mechanism for the initiation and progression of cancer on the cellular level is outlined. PACAP (10 nmol/L) induced a net rise in catecholamine release by adrenal slices. Leptin is differentially expressed at different adipose tissue sites, a situation which is even more pronounced in children.

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Experiments are described which aim to combine a protective cover with the enamel. The complement system is vital for protecting individuals against N. Neutrophils are the initial responders to bacterial infection or other inflammatory stimuli and comprise a key component of the innate immune response. Unlike most cell types examined, nonpermissive Chinese hamster ovary (CHO) cells readily underwent apoptosis upon infection with vaccinia virus (VV).

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The clinical literature on the use of noninvasive imaging to assess myocardial viability has evolved from predicting improvement in regional LV function to predicting patient-related outcomes, including heart failure symptom improvement and survival after revascularization. Southern Africa is good place to research role of fetal malnutrition in chronic diseases. The existing procedures for isolation of DNA are time consuming and range from several hours to few days.

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Since a number of hepatitis A transmission episodes have been described with such preparations during the past 10 years, their continued use seems to be questionable unless additional virus removal or inactivation steps are introduced to prevent the transmission of nonenveloped viruses. Sodium hypochlorite and ozone solution were used for sanitation of the abdominal cavity and intestinal lavage, and the intestinal anastomosis was coated with Ozonide (ozonized oil). Regulation of ammonia-dependent de novo purine biosynthesis was similar to that of glutamine-dependent purine biosynthesis. A description of methods and techniques, and a summary of clinical observations and applications in critically-ill patients are also included. Use of formed and injection molded parts provides for low-cost manufacturing, in contrast to the precision welded alternative designs.

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Therapeutic potential of arsenic trioxide with or without interferon-alpha for relapsed/refractory adult T-cell leukemia/lymphoma. Changes in the proteins of the outer segments of retinal rods in rats with tapeto-retinal dystrophies This anatomical cadaver study was intended to incrementally determine the precise relationship between the alar rim skin margin and the caudal aspect of the lateral crus of the nose.

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Hemoglobin (Hb) occurs in circulating red blood cells, neural tissue, and body wall muscle tissue of the nemertean worm, Cerebratulus lacteus. Investigations with drugs which inhibit synthesis of macromolecules has suggested that liver neoplasia may be accompanied by changes in response which may make the tumor less sensitive or more sensitive to regulation than the tissue of origin. Effect of para-aminobenzoic acid on the development of rat embryos when applied to pregnant females The potential for serious consequences from misinterpreting normal responses to the rapid adrenocorticotropin test. For these reasons the concept of reducing hospital stays with a concomitant reduction in hospital cost is very attractive.

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Blood glucose, tissue lipid peroxidation and plasma vitamin C were measured. A highly sensitive solid state (19)F-NMR strategy is described to determine the orientation and dynamics of membrane-associated peptides from specific fluorine labels. Future research and development should particularly address the needs of the aphasic population whose needs were not found to be met by currently available communication aids. Computer simulation results were obtained for a number of interesting cases.

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Assessment of patients in the emergency department who sustain blunt abdominal trauma represents a significant diagnostic challenge. There were 34 multidrug-resistant isolates which were resistant to oxacillin, ampicillin, cefazolin, cefmetazole, imipenem, and gentamicin.

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We recently cloned and characterized a novel low-affinity, high capacity plasma membrane monoamine transporter (PMAT) that is strongly expressed in the human brain and efficiently transports 5-HT and dopamine (DA). Increase in CPD photolyase activity functions effectively to prevent growth inhibition caused by UVB radiation.

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Cultured cerebellar granule neurons died with the characteristics of apoptotic death in the presence of superoxide anion or singlet oxygen. No differences were found between the structural characteristics of mesenteric resistance arteries of first (pressurized diameter approximately 350 microns), second (approximately 270 microns) or third (approximately 200 microns) order vessels isolated from normotensive rats and rats that had been treated with L-NAME.

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Whereas the mechanisms of these effects have not been studied in detail, changes in extracellular amino acid concentrations and certain anabolic hormones such as insulin are important mediators of these actions. On the effect of lung filtering and cardiac pressure on the standard properties of ultrasound contrast agent. Evaluation of the biocompatibility of a new method for heparin coating of a cardiopulmonary bypass circuit. Our unadorned atrial fibrillation: the challenge of new enigmas. Cyclosporin-responsive keratoconjunctivitis in the cat and horse.