Nefazan is an antiplatelet medicine, or blood thinner. It makes your blood flow through your veins more easily.

This means that your blood will be less likely to make a dangerous blood clot.

Taking Nefazan helps prevent blood clots if you have an increased risk of having them.

Your risk is higher if you have or have had:

• a heart attack
• unstable angina
• a stroke or "mini-stroke" (transient ischaemic attack or TIA)
• peripheral arterial disease
• an operation on your heart or blood vessels, such as a coronary stent insertion

Nefazan comes as tablets and is only available on prescription.

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Dendritic nanoparticles-the impact of ligand cross-linking on nanocore stability. The control system design allows both the pressure setpoint and hysteresis to be adjusted to overcome the difficulties inherent in differential pressure-activated, fixed resistance, open-loop shunts. Hyaluronan has delayed onset of efficacy but its benefit for pain may be longer lasting.

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However, the molecular mechanism of the Tax-induced NFkappaB activation remains unknown. Authors summarize both specific and non-specific signs of the pancreatic pseudoaneurysm obtained from duplex scan. canis immune sera, whereas the antigens from the other isolates showed only weak reactions with homologous and heterologous immune sera. Controversy over the efficacy of many topical wound treatments, particularly growth factors, is common, with many clinical practitioners still confused as to the real value of these agents. However, important objectives such as access to health care and avoiding impoverishment due to direct health care payments should be recognised from the start so that steady progress towards effective universal coverage can be planned and achieved.

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Quantification is based on the use of an internal standard with same chemical structure as the analyte but labeled with a stable isotope. PYY concentrations were significantly higher in CT subjects than in AN or control subjects. Numerous recent reports have described limitations in the quality of cardiopulmonary resuscitation. During a 1-year period, 438 women undergoing cesarean delivery were randomized into groups with and without approximation of Camper fascia with absorbable suture during closure of the abdominal incision.

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Endoscopy is commonly performed to evaluate symptoms of dyspepsia, especially in older patients after 45 years or with alarm symptoms. Electromagnetic pulses induce fluctuations in blood pressure in rats. To determine whether metal fragments can be shaken loose from phaco needles during surgery and embed in the iris.

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235 obese outpatients, aged 18-65 y with a body mass index (BMI) within the range 27-40 kg/m2. Programmed cell death: the influence of CD40, CD95 (Fas or Apo-I) and their ligands.

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Hepatitis B immunisation coverage of infants born to chronic carrier mothers in Victoria. We present here an infant who developed this complication of pulmonary barotrauma during cardiopulmonary resuscitative efforts. Sperm parameters (volume, liquefaction time, pH, viscosity, sperm count, motility, viability, and morphology).

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Adjunctive decompression gastrostomy has been a popular alternative to nasogastric suction in the care for general surgical patients suffering from postoperative ileus--avoiding discomfort and adverse sequelae of nasogastric tubes. Overprotection on the part of family and friends may facilitate psychosocial adjustment in the early months after an acute myocardial infarction rather than lead to cardiac invalidism. On the other hand, the great distances that separate individual groups of Evens and Evenks from each other might have led to preferential mating with geographic neighbors rather than with linguistically related peoples. The histological c-KIT markup is an easy and reliable method that can detect whether a desmoid tumor is sensitive to additional treatment with a tyrosine-kinase receptor inhibitor. It was found that aggregated mouse IgG (as well as IgGl) could stimulate the proliferation of the T cell hybridoma (T2D4) and other Fc gamma RII expressing T cells.

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Identification of FMO(GS-OX1) provides a molecular tool for breeding of Brassica vegetable crops with increased levels of this important GSL, which has implications for production of functional foods enriched with the cancer-preventive sulforaphane. A penetrating keratoplasty was performed, but rapidly failed because of corneal vascularization.

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Using Lentiviral vectors carrying the HGF transgene, we transduced SK-OV-3 and NIH:OVCAR-3 ovarian carcinoma cell lines to obtain stable autocrine and paracrine HGF receptor activation. A relationship between the life quality of the dysphonic individual and the vocal perception of listeners was not observed. NON-CORONARY INTERVENTIONS: Valvuloplasty remained the most frequent non-coronary intervention in Europe during 1994 with a total of 2622 mitral. The development of progressive, severe skin changes (purpura fulminans) is a serious complication of septicaemia, particularly meningococcal septicaemia.

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The structure of negative emotions in a clinical sample of children and adolescents. Cell viability assays represent an important technology in modern cell biology, drug discovery and biotechnology, where currently there is a high demand for simple, sensitive and cost-effective screening methods.

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A longitudinal study was made with 22-month follow-up in a Single Regeneration Budget area, and matched control area in South Manchester. Metabolites M-5 to M-8 were identified as monohydroxylated derivatives of ABT-378. Fast-ion data are acquired with a time resolution of approximately 1 ms, spatial resolution of approximately 5 cm, and energy resolution of approximately 10 keV.

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Parents planning a home birth need specific information beyond that which typically is covered in childbirth preparation classes geared for hospital couples. immitis larvae (both L3 and microfilariae), individual infected mosquitoes, pools of 30 mosquitoes (including a single infected mosquito), infected mosquitoes stored desiccated at room temperature for 7 mo, and whole blood from a dog infected with D. Growth of Pakistani children in relation to the 1990 growth standards. Cloning and characterization of Syrian hamster testosterone 7 alpha-hydroxylase, CYP2A9.

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The best chemical extractant for predicting plant metal concentrations was 0.1m CaCl(2). Urinary furosemide excretion and diuretic effects of the agent (urine volume and urinary sodium) were significantly greater at 12 am than at 12 pm in the sham-operated group of rats. The authors examined 6880 incident reports filed by physicians and nurses for three years at a national university hospital in Japan and evaluated the lag time between each incident and the submission of a report. Inefficacy of plasma perfusion in thrombotic thrombocytopenic purpura and early relapse after plasmapheresis In unc-25 mutants the GABAergic neurons have normal axonal trajectories and synaptic connectivity, and the size and shape of synaptic vesicles are normal.

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However, the appearance of ultrastructurally abnormal blasts in chronic lymphocytic leukemia cultures suggests that NaIO4 also stimulates the transformation of an abnormal subpopulation of lymphocytes. A unified model for functional and statistical epistasis and its application in quantitative trait Loci analysis. Viscosupplementation with hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee. In acute liver failure, an osmotic disturbance in the astrocyte, in combination with an alteration of cerebral blood flow results in overt brain edema and intracranial hypertension.

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Histologic examination shows interface dermatitis and keratinocyte necrosis in addition to acantolysis. alpha3beta1 and alpha6beta4 integrins were found in membrane projections of the migrating basal cells and also in suprabasal cell layers, suggesting their combined role in binding laminin-5. Viruses were given via intramuscular injection, and clinical response and immune function modulation were analyzed. This article provides a commentary on the progression of research over the last six decades into the neurobehavioral outcomes of children treated for intracranial tumors. The first branch of fistula penetrated into middle part of hyoid bone, and the second branch penetrated into the left cornu minor region.

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It was found that daily injections of ACTH-zinc-phosphate (5 un./100 g) to intact albino rats for 14 days result in a disturbance of the hepatocytes ultrastructure. This strain was used as the host for the subsequent introduction of fedl mutant alleles propagated on a second vector. All of the anions, except malate, were found to be conducted through the channel.

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Peristomal pyoderma gangrenosum after colectomy for Crohn disease. Their causes include hypertension, moyamoya disease, infection, systemic lupus erythematosis, and flow-related saccular aneurysms. The effects of intravenous arginine-vasopressin (AVP) on the endocochlear potential (EP) and systemic blood pressure (BP) were examined in the guinea pig. Removing rectal foreign bodies: is the ventouse gender specific? Frequency, characteristics and consequences of falls in a cohort of institutionalized elderly patients

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Nasopharyngeal tumor initially manifested as myofascial pain dysfunction syndrome. These measurements are consistent with previous work suggesting that good readers have reduced interhemispheric connectivity and are better at processing rapidly changing visual and auditory stimuli. For a comprehensive understanding of the possible differences in genomic DNA between nasopharyngeal carcinoma drug-resistant and drug-sensitive cells, we analyzed the genomic DNA of a nasopharyngeal carcinoma drug-resistant cell line CNE2/DDP and its parent cell line CNE2 with CGH.

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An impact of heatwaves on mortality was apparent in Vienna, although not as pronounced as in France and south-western Europe. After carbamazepine discontinuation, levels of IgA and IgM increased until reaching normal values over 3 years. secondary data analysis, we conducted stepwise linear regression equation modeling to determine which factors were significant predictors of sexual risk among various subgroups of bisexual Latino men. These were thought to be attributable to variations in measured mass distributions between amino acids and the corresponding precursors and to differences in the sensitivity of the exchange coefficients to mass distributions. The anterior cruciate ligament (ACL) was reconstructed by using treated porcine patellar tendon grafts or controls of untreated porcine grafts or allografts in 20 rhesus monkeys.

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No lethality was observed in animals infected with small doses of aerosol preparations. Site-specific genomic (SSG) and random domain-localized (RDL) mutagenesis in yeast. Young adult male Syrian hamsters were given intraperitoneal injections of 50 mg dibutyryl cyclic AMP twice daily for a period of three days.

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The staining was blocked by cholera toxin, which is specific for GM1, indicating that GM1 itself was the target antigen. We have identified a previously undescribed protein that we have named lacryglobin. Between September 1982-December 2004, 3,211 primary kidney transplant procedures were performed at The Ohio State University. Environmental oestrogens (TEXB-alpha) are separated from endogenous oestrogens (TEXB-beta), and the combined oestrogenic effect is determined from its proliferative effect (E-Screen assay). Moreover, no basic scientific investigations have been conducted to determine whether the success of an endoscopic arthrodesis is comparable to that of a conventional open procedure.

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Changes in coronary resistance and ventricular function resulting from acutely induced anemia and the effect thereon of coronary stenosis. Implementation of a quality system for the examination of occupational diseases. The functional significance of masticatory muscle direction was estimated using a mechanical model in two murid rodents: the Japanese field mouse (Apodemus speciosus) and the gray red-backed vole (Clethrionomys rufocanus). Each disease is the result of mutations within any of 10 specific structural proteins (keratins, laminins, collagens, integrins) within the basilar keratinocyte or the skin basement membrane zone.

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The rhesus monkey analogue of human lymphocyte antigen-G is expressed primarily in villous syncytiotrophoblasts. Instability in a multimode free-electron laser: Effects of electron energy drift. The CDS1 gene encoding CDP-diacylglycerol synthase in Saccharomyces cerevisiae is essential for cell growth. This study unveils new mechanisms by which cytokines play a role in the pathogenesis of CHF, thus underscoring the importance of targeting cytokines in heart failure.

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The aims of this study were to evaluate the extracolonic findings identified in patients undergoing minimal preparation abdomino-pelvic CT in place of barium enema or colonoscopy for the detection of possible colorectal carcinoma. Efficient solution-phase synthesis of multiple O-phosphoseryl-containing peptides related to casein and statherin. The effect of number of film layers was investigated in silages produced in wrapped big bales. Neonatal jaundice and molecular mutations in glucose-6-phosphate dehydrogenase deficient newborn infants.

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Remote substituents influence both the thermodynamics and kinetics of zinc binding to tris-pyridyl methanol derivatives. In our experience, the risks associated with fetal megalosomia were rather limited, but this is not a reason to minimize beyond measure the problem we are talking about.

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Many retrospective studies have been conducted to persuade us that a conservative transfusion trigger is a safe and prudent practice, but retrospective studies are not what we need. The data revealed that processing of vSAgs at either position 169-172 or 192-195 was sufficient for vSAg7 activation, and explain how vSAgs that lack some PC recognition sites can be activated by proteolytic processing. A reliable age for diagnosis using ERG is considered to be 1.5 years.

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Achievements and perspectives in the control of diseases of the nervous system Although, gene transfer techniques are believed to offer great therapeutic options for the future, the clinical data available today regarding this method are very limited and are derived from studies in patients with peripheral arterial disease. Correlation between salpingoscopic and laparoscopic staging in the assessment of the distal fallopian tube.

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To evaluate the effects of these compounds on metabolic enzymes, male Sprague-Dawley rats received daily oral doses for 4 days, and liver microsomes were prepared on day 5. Each of the cities was then randomly separated intervention and control community of 500,000 population.

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The ants that live in the swollen thorns (domatia) of Acacia drepanolobium are staple foods for patas monkeys (Erythrocebus patas). The content of a protein inhibitor of the cyclic nucleotides phosphodiesterase (PDE) in different retinal preparations as well as its distribution in the subfractions of rod outer segments (ROS) was studied.

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Novel drug delivery system of hollow mesoporous silica nanocapsules with thin shells: preparation and fluorescein isothiocyanate (FITC) release kinetics. A carcinoid syndrome is typically diagnosed in elderly patients, median age at diagnosis was 60 years in two large series. When the inhibition of gap junction was prevented by tolbutamide, neither ET-1 nor carbenoxolone were able to increase the levels of GLUT-1, GLUT-3, type I hexokinase or type II hexokinase, indicating that these events are closely related to gap junctions. Reaction norms with different shapes may be observed in various parts of the wing: the major effect is found between the basis and the tip of the wing, but in a similar way in the two species.

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E2F-1 suppresses extracellular signal-regulated kinase (ERK) phosphorylation through PAC1 and causes cancer cell death by apoptosis following treatment with a chemotherapeutic agent N-4-hydroxyphenylretinamide (4-HPR). On the glass covered with silver nanowires, high quality surface enhanced Raman scattering (SERS) spectra of sudan II (C18H16N2O) with enhancement factors of 10(5) were obtained.

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Hyperthermia may decrease the development of telangiectasia after radiotherapy. The TPA measurement may be a useful addition to previously reported cyst fluid markers to aid in preoperative differential diagnosis. Using P-element mutagenesis, we have isolated a mutant deficient in DSP1 functions.

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The configural properties of surfaces (surface contours) may play an important role in determining, for example, slant responses to a disparity gradient, and the marked anisotropy in favour of slant around a horizontal axis. Increased plasma amyloid beta protein 1-42 levels in Down syndrome. Concentrations of Cd and Zn were within current UK limits for potentially toxic elements in soils amended with sewage sludge. After 2 days of work with NMP, 10 of the 12 involved workers displayed acute irritant contact dermatitis of the hands.

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The results show that in elevated carbon dioxide, photosynthesis is restricted by the rate of end product synthesis. Absorption enhancers have been investigated since the 1960s, in order to assist the transfer of drugs across the paracellular space in the intestinal epithelium. Although antisera react strongly against homologous virus-like particles, there is evidence of some cross-reactivity.

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Measurement of myocardial infarct size by electron beam computed tomography: a comparison with 99mTc sestamibi. In conclusion, we show high expression of inhibin alpha subunit in zona reticularis of normal and hyperplastic adrenal glands as well as strong expression in virilizing adenomas. Species-specificity in localization of the cells containing certain biologically active substances is noticed both along the length of the tract and with respect to its epithelial layer. The relaxivity values of the variable conjugation constructs indicated that the conformation of the highly conjugated polymers was consistent with an extended conformation. An additional benefit of the survey meter method is the ability to clean rooms promptly for reoccupancy.

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Further, DWI rearrest data for 274 participants were available for analysis. Nasal provocations were performed with extracts of histamine, Dermatophagoides pteronyssinus (Dp) and mixed grass pollen (Mg) in patients with perennial and seasonal allergic rhinitis and in healthy subjects. After in vitro activation, CD8 T cells rapidly express effector molecules and cease their expression when the antigen is removed. Our results led us to postulate that the strong interaction taking place between virally incorporated ICAM-1 and cell surface-activated LFA-1 markedly enhances the efficiency of virus binding and entry, thus favoring greater infection by ICAM-1-bearing HIV-1 particles.

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Persistence of Pneumocystis carinii after effective treatment of P. This finding supports our previous report that the integration of oncornavirus proviral DNA is restricted to specific sites in the host cell DNA and suggests a specific mechanism for integration. The gold standard in the diagnosis of vasovagal syncope is in recent years the head up tilt test. Both EGF-R and EC-R were immunoprecipitated from lysates of overexpressing cells with antibodies against the extracellular domain of EGF-R. 63 of 68 consecutive patients who met criteria for acute cholecystitis were randomly assigned OC (31 patients) or LC (32 patients).

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Detection with tandem mass spectrometric techniques on a triple quadrupole instrument is feasible, and yields informative spectra devoid of coeluting interferences. Numerical efficiency scores were lower for the viscous material, indicating that such a measure is bolus dependent. Control of speech disorders with so-called speech adjustment instruments To determine the differences in complications and nursing care for patients receiving different pharmacological therapies after placement of an intracoronary stent.

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These results suggest that the XPC protein plays a critical role in initiating the cisplatin DNA damaging treatment-mediated signal transduction process, resulting in activation of the p53 pathway and cell cycle arrest that allow DNA repair and apoptosis to take place. trifolii strains RtTA1 and ANU843 and very weakly active in a mutant of strain ANU843 that lacks the regulatory nodD gene. Intracarotid dopamine infusion does not prevent acclimatization to hypoxia.

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Adequacy of state capacity to address noncommunicable disease clusters in the era of environmental public health tracking. These processes appear perpendicular to the ependymal surface and end in contact with the basal membrane of hypothalamic capillaries.

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These mutants were constructed and the proteins were over-expressed in E. RESPONSES OF COLD- AND WARM-ADAPTED DOGS TO INFUSED NOREPINEPHRINE AND ACUTE BODY COOLING. Intelligent, impedance-regulated, pulsed coagulation in a porcine renal artery model. Historically, sexual arousal has usually referred to a central physiological state, but there has been much less agreement on its relation to motivation, emotion, and - for males - penile erection and ejaculation. Does random pattern skin flap supply adequate circulation to the underlying muscle through musculocutaneous perforators by reverse flow?

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Effect of cholinergic antagonists on sympathetic ganglionic transmission of vasomotor reflexes from the carotid baroreceptors and chemoreceptors of the dog. The participation, if any, of the purinergic system in the physiology of the pineal gland is still far from being characterized.