Nifedipine is used alone or in combination with other drugs to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used for certain types of chest pain (angina). It may help increase your ability to exercise and decrease the frequency of chest pain attacks. It should not be used to treat chest pain when it occurs. Use other medications (e. g. , sublingual nitroglycerin) to relieve attacks of chest pain as directed by your doctor. Consult your doctor or pharmacist for more details. This medication is known as a calcium channel blocker. It works by relaxing and widening blood vessels so blood can flow more easily. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat certain blood circulation disorders (Raynaud's syndrome).

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Using proton magnetic resonance spectroscopic imaging, we studied the cerebellum of 9 patients with cerebellar degeneration and of 9 age-matched normal control subjects. The possibility of late untoward consequences, such as aneurysm formation, perforation, and accelerated vascular disease, is of significant concern. Ammonium perchlorate effects on thyroid function and growth in bobwhite quail chicks. Experiments were also carried out with different cell-cycle populations obtained after mitotic selection (V79) or after serum stimulation of plateau-phase cells (Widr). The double chitin-binding domain organization of Ag-Aper1 suggests that each protein molecule is able to link two chitin polymer chains.

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We investigated the influence of stimulus notation and processing speed on this bilateral redundancy gain (B-RG) in number comparison. Biographical data, tumour characteristics, treatment and outcome from 190 patients with thyroid carcinoma from 1970 to 2000 were reviewed retrospectively. In vivo intraperitoneal concordant xenotransplantation of APA encapsulated rat islets reversed the diabetic state of streptozotocin diabetic mice for a longer period, than APPH islet grafts.

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There was not a significant difference in the mean distance between hometown and practice location for physicians from nonmetro hometowns compared to those from metro hometowns. However these amino acids did not show a concentration-dependency. Camelpox virus (CaPV) bovine herpesvirus-1 (BHV-1), vesicular stomatitis virus (VSV) and border disease virus (BDV) could be propagated in these cells.

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Moreover, some forms of hyperthyroidism occur exclusively during this period. We used a computer-based prediction algorithm to identify probable coiled-coil segments at the N-termini of G protein alpha, beta and gamma subunits. To describe the composition and role of the data safety and monitoring board (DSMB) for the National Institute of Mental Health (NIMH) Collaborative HIV/STD Prevention Trial. Results of tests for discriminating the native protein conformations from large sets of decoy proteins, show that the new continuous distance- and orientation-dependent potentials present significantly improved performance. Thirty-eight patients who underwent the operation of aortocoronary shunting showed an improvement of the contractile capacity of the myocardium, and a longer survival as compared with those treated medically.

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Collecting efficiencies of filter papers for sampling lead fume. CM1 immunoreactivity was absent in the nervous system of caspase-3-deficient mouse embryos and in neurons cultured from caspase-3-deficient mice.

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Data were collected from inpatient notes and incident reports of patients admitted to hospitals over a 6-year period. Rheumatic mitral valve stenosis is associated with impaired flow-mediated dilatation. Differential cross sections for secondary electron production by proton impact. The results suggest that a decrease in venous resistance mediated through a beta-adrenergic mechanism is important in increasing venous return, whereas an increase in venous resistance mediated through an alpha-adrenergic mechanism is responsible for a decrease in venous return.

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The question then becomes one of whether TRL are directly or indirectly involved in atherogenesis. Galvanic stimulation induced a body sway not significantly different from the control group suggesting that the patients selected for cochlear implantation, and with an otherwise reduced postural control, are sensitive to electrical stimulation of the vestibular nerve. An acute animal model has been developed in the chinchilla for the study of perilymphatic fistulas.

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To evaluate the effects of combined treatment of glutamine (Gln) and recombinant human growth hormone(rhGH) on intestinal barrier function following portal hypertension surgery. Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Removal of the entire C1qr2s2 did not occur when C1 INH preparations were first neutralized by the addition of purified activated C1s. The chromosomal genotypes of 277 isolates of 16 serotypes of Streptococcus agalactiae were characterized by analysis of electrophoretically demonstrable allele profiles at 12 metabolic enzyme loci.

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Auditory scene analysis by European starlings (Sturnus vulgaris): perceptual segregation of tone sequences. Cytogenetic analysis was performed using a trypsin-Giemsa banding technique.

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We also show that ssDNA manifests slower and distinct translocation kinetics in comparison to dsDNA. Cataracts are common in Mali, where there are 60,000 people awaiting surgery for blindness caused by cataracts.

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More than 60,000 cases of viral hepatitis are reported to the U.S. Microsurgical technique to improve the insertion of totally implantable arterial device (TIAD) in presence of hepatic artery anomalies.

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Reasons for not taking such a conservative approach are the possibilities of malignancy and the risk of recurrence. Serum IgG, IgA, IgM, Complement C3 assay and cell mediated immunity (CMI) tests were performed in 33 patients of empyema thoracis, and 14 healthy age matched controls. Difficulties inherent in all of these steps to adult life are magnified by chronic ill health.

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Angiotensin II receptor blockers represent a class of effective and well-tolerated orally active antihypertensive drugs in the general hypertensive population and in diabetic patients. We propose that miR398 is a key factor in copper homeostasis in plants and regulates the stability of mRNAs of major copper proteins under copper-limited conditions.

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The variables used as predictors were year of prostatectomy, type of admission (planned, emergency), location of the hospital (rural, metropolitan), type of procedure (TURP, open), and teaching status of the hospital. Neither BrdU nor GFAP inmunostaining revealed significant differences between the two groups, suggesting that adult cell generation, i.e., increases in the number of glial elements, has no significant role in the changes detected in the number of Nissl-stained sections. The variational formulation permits a more flexible local control of contrast adjustment and attachment to data. The dural sinuses were viewed on MRV images for the presence of filling defects. To study the relationship between the expression of glutathione S-transferase-pi (GST-pi) in operative specimens and chemoresistance in patients with ovarian cancer.

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Polyacrylamide gel electrophoresis of the partially purified transhydrogenase in the presence of sodium dodecyl sulphate showed major increases in protein-stained bands corresponding to between 70 000 and 54 000 daltons. A dedicated research residency can increase the rate of trainees ultimately choosing academic careers, but there are significant risks for these trainees that they will not be able to sufficiently accommodate both clinical and research training roles.

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Cellular responses in both prokaryotes and eukaryotes to high temperature include the synthesis of a set of highly conserved proteins known as the heat shock proteins. To determine the effects of mechanical devices for pelvic organ prolapse. This paper describes the results of a two year project to design a model curriculum of health care informatics for Dutch higher professional education. A human endogenous long terminal repeat provides a polyadenylation signal to a novel, alternatively spliced transcript in normal placenta. The cumulative patency rate of AFs was improved, and early failure rates were reduced when compared with the preceding institutional experience.

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Our study objectives were to assess this accuracy and compare the percentage time within therapeutic range (PTWTR) based on HAT data to that obtained with testing through an anticoagulation clinic service (ACS). Effects of PBMC-derived histamine-releasing factors on histamine release from human skin and lung mast cells. To establish the sensitivity, specificity, positive (PPV) and negative predictive value (NPV) of serum S-100 beta protein (sSB) in patients with malignant melanoma (MM), based on its concentration in the peripheral blood and the likelihood ratio (LR) for the whole group of patients with MM, as well as for each separate clinical stage. Commentary on the results of the economic survey of veterinary practice in Atlantic Canada - A reply.

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Patients with suspected AVN were examined using either radiographs or radiographs and MRI. Plasma concentrations of cortisol (CORT) and corticosteroid binding globulin (CBG) were determined. CT scans of the chest do not add clinically useful information to the standard chest radiographs in the initial assessment of sarcoidosis in patients presenting with the typical standard radiological patterns.

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The anatomy of the bronchial arteries was studied, with special reference to their preservation during the radical dissection of the upper mediastinum lymph nodes. However, cells containing a precise endogenous gene replacement of SIC1 with SIC1-0P (all nine phosphorylation sites mutated) were fully viable. Antibiotic potentiation of host defence mechanisms may be of potential clinical importance in the outcome of infections.

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The UGIE procedures were categorized as appropriate or inappropriate based on GFHGNP recommendations, and diagnostic efficiency was compared in the 2 groups with the chi2 test followed by multivariate logistic regression analysis. Orthotopic liver transplantation restores the expected correlation of serum leptin with measures of body fat mass within the treatment group.

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These studies suggest that the organization of cytoplasmic microtubules may participate in the shape-related regulation of cell function. Primary care providers need practical methods for managing patients who screen positive for at-risk drinking. A quantitative assessment of the role of the chaperonin proteins in protein folding in vivo.

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However, the simple design offers the potential to perform experiments under more controlled conditions than larger and, consequently, more complex model ecosystems, while maintaining relatively high ecologic realism compared with standard laboratory tests. Retrospective chart review of patients with histologically diagnosed grade 2/3-VIN who had at least one year of follow-up. Biphasic kinetics of colchicines-tubulin interaction has been explained in light of the variation in the residues around the drug-binding site on beta-tubulin. Since then, a meager number of products have ripened while the rest have turned sour. The in vitro growth rates of control cells and wild-type p53-modified cells were similar in the absence of cisplatin.

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We propose a new edge-driven stochastic prior image model and obtain the maximum a posteriori (MAP) estimate under this model. Endocrine and metabolic changes in neonatal calves in response to growth hormone and long-R3-insulin-like growth factor-I administration. anthracis adapts very quickly to the intracellular environment, and our analyses identified metabolic pathways that appear to be important to the bacterium during intracellular growth, as well as individual genes that show significant induction in vivo. Comparison of natural estrogen removal efficiency in the conventional activated sludge process and the oxidation ditch process. Higher than normal levels of host cell DNA damage are therefore anticipated, and they have indeed been observed in the case of alkylation damage, together with an inefficiency in the capacity of relevant enzymes to repair this damaged DNA.

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L-arginine therapy, which could augment urethral smooth muscle relaxation by increasing NO production, may be useful for partially restoring the urethral relaxation mechanism in DM. One aspect, detrusor contraction strength during voiding, can be measured by the isovolumetric detrusor pressure attained if flow is interrupted mechanically (a stop test). Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.

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Under captopril, the PRA rose significantly, whereas there was no unequivocal change in the excretion of renal prostaglandins. Apart from oral drug treatment, drug therapy in acne vulgaris comprises topical treatment with agents with a primarily keratolytic action (e.g. It is not uncommon in a system of job-sharing in which several members of the health service (surgeons, physiotherapists, social workers, general practitioners) must co-ordinate their work, for the patient--if he does not involve himself--to fall by the wayside.

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The three-dimensional structure of the N-terminal domain of an archaeal TFIIB, which has high sequence homology with eucaryal analogues, is strikingly similar to that of the C-terminal zinc ribbon of the eucaryal transcription elongation factor TFIIB. Low concentration of 5HPETE, which is thought to be produced during cell activation, had minimal effect on cytosolic free calcium by itself but dose-dependently augmented FMLP-stimulated increase in cytosolic free calcium in the presence or absence of extracellular calcium without converting to LTB4.

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Different tissues and plant parts, showed notable differences in their percentage distribution. Immunosuppressive therapy for idiopathic membranous glomerulopathy The workshops emphasized active learning using role-play to provide skills in educational planning, teaching styles, evaluation, and feedback.

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However, the influence on platelet function is not fully explained. Overexpression of myristoylated TGF-betaRI and TGF-betaRII cytoplasmic tails caused constitutive nuclear translocation of a green-fluorescent-protein-Smad2 construct in COS-1 cells, and constitutive activation of a PAI-1 reporter plasmid in mink lung cells. The application of capillary electrophoresis and of reversed-phase liquid chromatography coupled to electrospray mass spectrometry is presented for the analysis of microcystins isolated from toxic strains of Microcystis aeruginosa.

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At a higher integration level the development of organ anlagen in vitro has been employed in assays for developmental toxicity. With this method, both suggestive and autosuggestive procedures are used for anxiolysis, relaxation, sedation and analgesia of the patient.

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When symptoms and signs are more profound hospital admission is indicated. Genome assembly and contig automatic annotation data are also available in the same working environment.

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The role of the plain X-ray in the assessment of prostatic symptoms. Most previous studies have investigated the neurochemical bases of social behavior and aggression independently, as opposed to how these behaviors are regulated in concert.

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Demyelination of nerve fibers in pathogenesis of peripheral nervous system diseases Locomotor activity-inhibiting, anticonvulsant, muscle relaxant, analgesic, and antimicrobial properties of 2-methyl-3-pyridinium-acetylamino-4(3H)-quinazolinone chloride (1), 2-methyl-3-(4-methylpyridinium)acetylamino-4(3H)-quinazolinone chloride (2), 2-methyl-3-(4-ethylpyridinium)acetylamino-4(3H)-quinazolinone chloride (3), 2-methyl-3-(3-carboxamidopyridinium)acetylamino-4(3H)-quinazolinon e chloride (4), and 2-methyl-3-(4-carboxamidopyridinium)-acetylamino-4(3H)- quinazolinone chloride (5) were investigated. The wall movement greatly increases the number of particle-wall and particle-particle forces at the Coulomb criterion. Part III--Teachers and parents response to a mobile dental system at school. How can the autonomy of the patients be respected under these circumstances?

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No observed response followed chemotherapy with doxorubicin and carboplatin. In all brains, including controls, vascular endothelial cells and residual blood plasma were weakly stained.

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The potential role of basic fibroblast growth factor (bFGF) as a mediator of cell-cell interactions in the growth and development of the testis was examined. In vivo characterization of the Nkx2.1 promoter/enhancer elements in transgenic mice. In patients with PSX, cataract surgery induced similar endothelial cell changes without increased endothelial cell loss postoperatively. Substance P and Octopus salivary gland-specific TK, oct-TK-I, completely failed to activate oct-TKRPR, whereas a Substance P analog containing a C-terminal Arg-NH2 exhibited equipotent activation of oct-TKRPs.

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Only six newborns had unstable hips to a degree requiring treatment. Preoperative chemotherapy for colorectal liver metastases: impact on hepatic histology and postoperative outcome. Conversely, histamine N-methyltransferase, the other important enzyme inactivating histamine, is a cytosolic protein that can convert histamine only in the intracellular space of cells. Sclerosing hemangioma does not appear to have been implicated previously in this connection. Continuous hypopharyngeal pH measurements in spontaneously breathing anesthetized outpatients: laryngeal mask airway versus tracheal intubation.

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Color Doppler sonographic analysis of uterine and ovarian artery blood flow in women with polycystic ovary syndrome. Common respiratory viruses were also screened from nasopharyngeal suction samples by antigen detection EIA. Thus, memories will often contain some small errors and occasionally some large errors.

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Furthermore, an adrenergic component in the activation of the PCKC cAMP system is indicated by the effects of certain catecholamines on influenza virus yield. The isotope contents of TMV, B3, and B6 which appear in given intervals after inoculation in newly infected leaf cultured in nutrient containing N(15)H(4) have been compared. It is suggested that sheep rather than human bacterial strains should be used in antibody studies of ovine periodontitis. We evaluated the effects of paternal smoking on testicular function, sperm fertilizing capacity, embryonic development, and blastocyst capacity for implantation.

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The mutations introduced had complex effects on virulence, including antagonistic epistasis and trade-offs for virulence towards different pvr2 alleles. We present clinicopathological and cytological findings of a well-defined breast mass in a patient with history of primary renal carcinoid tumor. These data are consistent with the conventional view of myelin-reactive T-cells as pathological effector cells. To explore the significance of osteocyte apoptosis in steroid-induced osteonecrosis of the femoral head. Hydrophilic substituents on the anilino nitrogen abolish agonist activity or produce antagonists of CCK.