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Virustat (Acyclovir)
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Acyclovir

Virustat is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection. It can be taken by mouth, applied as a cream, or injected.Common side effects include nausea and diarrhea. Potentially serious side effects include kidney problems and low platelets. Greater care is recommended in those with poor liver or kidney function. It is generally considered safe for use in pregnancy with no harm having been observed. It appears to be safe during breastfeeding. Virustat is a nucleoside analogue that mimics guanosine. It works by decreasing the production of the virus's DNA.Virustat was patented in 1974, and approved for medical use in 1981. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. It is available as a generic medication and is marketed under many brand names worldwide. The wholesale cost as of 2014 to 2016 was between US$0.03 and US$0.12 for a typical dose by mouth. The cost of a typical course of treatment in the United States is less than US$25. In 2016 it was the 195th most prescribed medication in the United States with more than 3 million prescriptions.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Ophthalmic Virustat is used to treat an infection of the eye caused by herpes simplex virus. Virustat is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the eye.

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La Crosse virus (LACV), family Bunyaviridae, is a mosquito-borne virus recognized as a major cause of pediatric encephalitis in North America with 70-130 symptomatic cases each year. Flow cytometry has become the preferred technique by which critical clinical evaluations are made such as CD4 counts and aneuploid analyses. Isolation and characterization of two chitinase-encoding genes (cts1, cts2) from the fungus Coccidioides immitis. For this purpose, telephone counseling interventions have considerable potential.

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This highly interactive clinical workstation now allows the clinicians at a large primary care practice (30,000 ambulatory visits per year) to use online information resources and fully electronic patient records during all patient encounters. Three juvenile sheep underwent implantation of a new annuloplasty system into the posterior mitral annulus without tissue annulus plication. Good tolerability and safety of the study drug was confirmed during the active run-in phase of the ADVANCE study.

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An alternative premedication and induction regime for cats with a decreased cardio-vascular reserve. Effects of lung volume on lung and chest wall mechanics in rats. Beta-cell hypersecretion and not reduced hepatic insulin extraction is the main cause of hyperinsulinemia in obese nondiabetic subjects. Quantitatively, there was a significant 2- to 3-fold increase in type II collagen and aggrecan expression beginning at day 5 of culture and the difference was maintained through 10 days of cultures. In all cases, the 1.5-Mb size of the HNPP deletion was confirmed by EcoRI dosage analysis using a CMT1A-REP probe.

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This plan simultaneously expands access to care and aims to contain health care costs. A Bayesian model of AFLP marker evolution and phylogenetic inference. Multiple analyses of variance in SPSS version 11.5 was used in the comparison of the scores obtained from the instrument. Importantly, a role for alloreactive natural killer cells in mediating GvL without GvHD has emerged in patient studies of MHC haplotype-mismatched alloHSCT. FNA cytology of collagenous spherulosis: recognizing a benign breast lesion.

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Regulation of COX-2 mediated signaling by alpha3 type IV noncollagenous domain in tumor angiogenesis. Direct addition of tri-iodothyronine to the incubation medium had no effect on mitochondrial incorporation. The reported correlations probably represent an underestimation of the true strength of the association because of a greater loss to follow-up among subjects with higher blood pressure and the effects of antihypertensive medication in adulthood. Long-term nasogastric feeding and complications of acute gastric ulcer in two elderly patients

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Ashkenazi community is not unwilling to participate in genetic research. Rabbit bones in culture produce specific collagenase and neutral metallo-proteinase activity in latent forms that can be activated by either 4-aminophenylmercuric acetate or trypsin. A new task was developed in which memory for the content of events could be assessed in conjunction with memory for both source and temporal information. p53-Independent ceramide formation in human glioma cells during gamma-radiation-induced apoptosis. All subjects showed a significant increase in gaze slip on the first day of their mission, suggesting that increased vestibular suppression was occurring.

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The distribution of herpes simplex virus (HSV) subtypes within the population, correlation of HSV culture result with duration of disease and prescribing habits of doctors were also examined. We concluded that TCD is valuable in detecting arterial stenosis in SCD and will lead to consideration of these patients for intensive therapy, such as bone marrow transplantation (BMT) or transfusion regimes.

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Structural analysis of the BRM2 gene involved in melanin biosynthesis of the Japanese pear pathotype of Alternaria alternata suggested that this gene encodes 1,3,8-trihydroxynaphthalene reductase. A phylogenetic analysis of 18S rDNA-sequence data aligned by secondary structure constraints, or a subset of the data corresponding to all nucleotides found in the helices, provide unambiguous evidence supporting monophyly of Sarcocystis.

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A series of 19 children with congenital nasal dermoid cyst or fistulas admitted in our department between 1978 and 1992 was reviewed in a retrospective study. Using the PLant-ATmosphere INteraction (PLATIN) model, the significance of the aforementioned meteorological parameters on ozone uptake is examined. Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation. These data indicate that correction of emotional activity in stutterers should be made at early periods of their life. The method is applied and the spectra are calculated for various different cases.

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Intragastric CCl4 inhibited the activity of and lowered the levels of the major components of the hepatic monoohygenase enzyme system in one-month rats. Thus, unawareness may have different forms such as anosognosia, neglect, and alexithymia or unawareness of emotions. We investigated whether artificial surfactant modified pulmonary fibrosis following the intratracheal administration of bleomycin (BLM 3.75 mg/kg) in rats.

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Ability of humans to smell geosmin, 2-MIB and nonadienal in indoor air when using contaminated drinking water. Clinicopathologic features of primary and metastatic neoplastic disease of the liver in dogs.

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Selected patients may benefit from intravenous prostanoids, although their efficacy is unconstant. Actinic keratosis is an early in situ squamous cell carcinoma: a proposal for reclassification. Intrarenal arteriosclerosis and impairment of kidney function in NIDDM subjects.

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